Research Topics
| Seth A EisenSummaryCountry: USA Publications
| Collaborators
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Detail Information
Publications
Co-twin control study of relationships among combat exposure, combat-related PTSD, and other mental disordersKarestan C Koenen
Women s Health Sciences Division, National Center for PTSD, VA Boston Healthcare System, Boston, Massachusetts 02114, USA
J Trauma Stress 16:433-8. 2003..We conclude C-PTSD comorbidity persists after controlling for shared vulnerability. Combat exposure is directly and indirectly, through C-PTSD, associated with increased risk for other mental disorders...- Gulf War veterans' health: medical evaluation of a U.S. cohortSeth A Eisen
Veterans Affairs Medical Center, Washington University School of Medicine, St Louis, Missouri 63106, USA
Ann Intern Med 142:881-90. 2005..United States military personnel reported various symptoms after deployment to the Persian Gulf during the 1991 Gulf War. However, the symptoms' long-term prevalence and association with deployment remain controversial... - Association between exposure to childhood and lifetime traumatic events and lifetime pathological gambling in a twin cohortJeffrey F Scherrer
Department of Psychiatry, Washington University School of Medicine, and Research Service, St Louis Veterans Affairs Medical Center, St Louis, Missouri 63110, USA
J Nerv Ment Dis 195:72-8. 2007..These associations are partially accounted for by psychiatric covariates and genetic and family environmental factors... - Posttraumatic stress disorder; combat exposure; and nicotine dependence, alcohol dependence, and major depression in male twinsJeffrey F Scherrer
St Louis Veterans Affairs Medical Center, Research Service, St Louis, MO 63106, USA
Compr Psychiatry 49:297-304. 2008..These findings suggest comorbid PTSD may represent a genetically mediated vulnerability to psychopathology after trauma... - Chronic multisymptom illness complex in Gulf War I veterans 10 years laterMelvin S Blanchard
Medical and Research Services, St Louis Veterans Affairs Medical Center, St Louis, MO 63106, USA
Am J Epidemiol 163:66-75. 2006..It is likely to be a common, persistent problem among veterans returning from the current Gulf War... - Genetic and environmental contributions to nicotine, alcohol and cannabis dependence in male twinsHong Xian
Research Service, St Louis Veterans Affairs Medical Center VAMC, St Louis, MO 63106, USA
Addiction 103:1391-8. 2008..To compute the common and specific genetic and environmental contributions to nicotine dependence (ND) alcohol dependence (AD) and cannabis dependence (CD)... - Nicotine dependence subtypes: association with smoking history, diagnostic criteria and psychiatric disorders in 5440 regular smokers from the Vietnam Era Twin RegistryHong Xian
Research Service, St Louis Veterans Affairs Medical Center, 915 North Grand Boulevard, St Louis, MO 63106, USA
Addict Behav 32:137-47. 2007..Empirically derived subtypes of nicotine dependence are mostly characterized by increasing severity. Suggestions for refinement of nicotine dependence diagnostic criteria are discussed... - Effect of genes, environment, and lifetime co-occurring disorders on health-related quality of life in problem and pathological gamblersJeffrey F Scherrer
Research Service, St Louis Veterans Affairs Medical Center, St Louis, Missouri 63106, USA
Arch Gen Psychiatry 62:677-83. 2005..Although these consequences and correlates have been reported, little is known about the health-related functional impairment associated with gambling... - Differential etiology of posttraumatic stress disorder with conduct disorder and major depression in male veteransQiang Fu
Department of Community Health, Saint Louis University School of Public Health, St Louis, Missouri 63104, USA
Biol Psychiatry 62:1088-94. 2007..Epidemiologic studies reveal that posttraumatic stress disorder (PTSD) is highly comorbid with both conduct disorder and major depression in men. The genetic and environmental etiology of this comorbidity has not been examined... - Course of pathological gambling symptoms and reliability of the Lifetime Gambling History measureCarolyn E Sartor
Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, United States
Psychiatry Res 152:55-61. 2007..Evidence is also provided for the utility of the LGH in assessing lifetime pathological gambling symptoms... - Heritability of SF-36 among middle-age, middle-class, male-male twinsJames C Romeis
Comparative Aging and Health Status Laboratory, Department of Health Management and Policy, School of Public Health, Saint Louis University, St Louis, MO 63104 1314, USA
Med Care 43:1147-54. 2005.... - Genetic vulnerability and phenotypic expression of depression and risk for ischemic heart disease in the Vietnam era twin study of agingHong Xian
Research Service, St Louis Veterans Affairs Medical Center, St Louis, Missouri 63103, USA
Psychosom Med 72:370-5. 2010..To determine if depression contributes to incident heart disease after accounting for genetic, behavioral, and medical factors associated with both conditions... - Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin designJulia D Grant
Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, St Louis, MO 63110, USA
Psychol Med 36:109-18. 2006..Early alcohol use is associated with abuse and dependence of licit and illicit substances later in life. The role of genetic and environmental factors in this association is not conclusive... - Genetic and environmental contributions to pathological gambling symptoms in a 10-year follow-upHong Xian
Research Service, St Louis Veterans Affairs Medical Center, St Louis, Missouri 63106, USA
Twin Res Hum Genet 10:174-9. 2007..This may reflect the changed social-cultural environment between 1992 and 2002, characterized by increasing access to legalized gambling... - Factors associated with pathological gambling at 10-year follow-up in a national sample of middle-aged menJeffrey F Scherrer
Research Service, Veterans Affairs Medical Center, St Louis, MO 63106, USA
Addiction 102:970-8. 2007..Co-twin analyses accounted for familial contributions to past-year gambling problems... - Latent class typology of nicotine withdrawal: genetic contributions and association with failed smoking cessation and psychiatric disordersHong Xian
Department of Internal Medicine, Division of General Medical Sciences, Washington University School of Medicine, St Louis, MO, USA
Psychol Med 35:409-19. 2005..However, relatively little is known about how to characterize the severity of withdrawal, including whether withdrawal subtypes exist in male smokers. If so, do these subtypes represent quantitative or qualitative differences?.. - TNF-? antagonist use and risk of hospitalization for infection in a national cohort of veterans with rheumatoid arthritisMichael A Lane
Washington University, St Louis, Missouri, USA
Medicine (Baltimore) 90:139-45. 2011..We conclude that patients with RA who are treated with TNF-? antagonists are at higher risk for hospitalization for infection than those treated with other DMARDs. Prednisone use is also a risk factor for hospitalization for infection... - Genetic studies of pathological gambling: a review of methodology and analyses of data from the Vietnam Era Twin RegistryKamini R Shah
St Louis Veterans Affairs Medical Center, Washington University School of Medicine, 915 North Grand Boulevard, St Louis, MO 63106, USA
J Gambl Stud 21:179-203. 2005.... - Depression increases risk of incident myocardial infarction among Veterans Administration patients with rheumatoid arthritisJeffrey F Scherrer
Research Service, St Louis Veterans Affairs Medical Center, St Louis, MO 63106, USA
Gen Hosp Psychiatry 31:353-9. 2009..This study evaluates whether depression is a risk factor for incident myocardial infarction (MI) in Department of Veterans Affairs (VA) patients with rheumatoid arthritis (RA) between 30 and 79 years of age... - Shared genetic risk of major depression, alcohol dependence, and marijuana dependence: contribution of antisocial personality disorder in menQiang Fu
Missouri Alcoholism Research Center at Washington University, Department of Psychiatry, Washington University School of Medicine, 40 N Kingshighway Blvd, Suite 2, St Louis, MO 63108, USA
Arch Gen Psychiatry 59:1125-32. 2002..We examined the contribution of genetic effects associated with ASPD to the comorbidity of MD and substance use disorders... - Risk of non-melanoma skin cancer in a national cohort of veterans with rheumatoid arthritisWassila Amari
Department of Medicine, Division of Rheumatology, Washington University School of Medicine, St Louis, MO 63110, USA
Rheumatology (Oxford) 50:1431-9. 2011..To determine the incidence of and risk factors for non-melanoma skin cancer (NMSC) in a national cohort of veterans with RA... - The heritability of failed smoking cessation and nicotine withdrawal in twins who smoked and attempted to quitHong Xian
Research Service, St Louis, MO 63106, USA
Nicotine Tob Res 5:245-54. 2003..The risk of experiencing nicotine withdrawal after a quit attempt was related partly to genetic vulnerability; lifetime risk for both failed cessation and nicotine withdrawal was related partly to genetic factors that were correlated... - Herpes zoster risk factors in a national cohort of veterans with rheumatoid arthritisJay R McDonald
St Louis Veterans Affairs Medical Center, St Louis, Missouri 63106, USA
Clin Infect Dis 48:1364-71. 2009..Herpes zoster occurs more commonly in patients taking immunosuppressive medications, although the risk associated with different medications is poorly understood... - Late prevalence of respiratory symptoms and pulmonary function abnormalities in Gulf War I VeteransJoel B Karlinsky
Department of Veterans Affairs Medical Center and Division of Pulmonary Medicine, Boston University School of Medicine, Boston, Mass, USA
Arch Intern Med 164:2488-91. 2004..Published reports have documented an increased prevalence of self-reported respiratory symptoms among servicemen deployed during the 1990-1991 Gulf War. We evaluated whether this deployment resulted in long-term adverse respiratory effects... - Health of US veterans of 1991 Gulf War: a follow-up survey in 10 yearsHan K Kang
Department of Veterans Affairs, Environmental Epidemiology Service, Washington DC 20420, USA
J Occup Environ Med 51:401-10. 2009..To assess periodically the health status of a cohort of 1991 Gulf War veterans by comparing various health outcomes with those of their military peers who were not deployed to the Gulf... - Is trauma a causal agent of psychopathologic symptoms in posttraumatic stress disorder? Findings from identical twins discordant for combat exposureMark W Gilbertson
Department of Research Service, Manchester VA Medical Center, 718 Smyth Rd, Manchester, NH 03104, USA
J Clin Psychiatry 71:1324-30. 2010..The current study tests this hypothesis... - Does marijuana use have residual adverse effects on self-reported health measures, socio-demographics and quality of life? A monozygotic co-twin control study in menSeth A Eisen
Research and Medical Service, St Louis VAMC and Department of Internal Medicine, Washington University School of Medicine, St Louis 63106, USA
Addiction 97:1137-44. 2002..To assess the effects of former heavy marijuana use on selected aspects of health... - Mental health of US Gulf War veterans 10 years after the warRosemary Toomey
Toomey, Psychology Department, Boston University, 648 Beacon Street, 6th Floor, Boston, MA 02215, USA
Br J Psychiatry 190:385-93. 2007..Gulf War veterans reported multiple psychological symptoms immediately after the war; the temporal course of these symptoms remains unclear... - Common genetic risk of major depression and nicotine dependence: the contribution of antisocial traits in a United States veteran male twin cohortQiang Fu
Department of Community Health, St Louis University School of Public Health, St Louis, Missouri 63104, United States of America
Twin Res Hum Genet 10:470-8. 2007.... - Spouses of Persian Gulf War I veterans: medical evaluation of a U.S. cohortSeth A Eisen
Medical Service, St. Louis Veterans Affairs Medical Center, St. Louis, MO 63106. USA
Mil Med 171:613-8. 2006..We conclude that, 10 years after GW I, the general physical health of spouses of GW I DV is similar to that of spouses of NDV... - A twin registry study of the relationship between posttraumatic stress disorder and nicotine dependence in menKarestan C Koenen
Department of Society, Human Development, and Health, Harvard School of Public Health, 677 Huntington Avenue, Kresge 613, Boston, MA 02115, USA
Arch Gen Psychiatry 62:1258-65. 2005..Recent studies indicate a strong association between posttraumatic stress disorder (PTSD) and nicotine dependence (ND). However, the explanation for the association remains unclear... - A high risk twin study of combat-related PTSD comorbidityKarestan C Koenen
Women s Health Sciences Division 116B 3, National Center for PTSD, VA Boston Healthcare System, MA 02130, USA
Twin Res 6:218-26. 2003.... - Common genetic liability to major depression and posttraumatic stress disorder in menKarestan C Koenen
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, United States
J Affect Disord 105:109-15. 2008..The degree to which a common genetic liability explains the etiology of the MD-PTSD association has not been quantified and has important implications for research and prevention... - Pretrauma cognitive ability and risk for posttraumatic stress disorder: a twin studyWilliam S Kremen
Department of Psychiatry and Center for Behavioral Genomics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Arch Gen Psychiatry 64:361-8. 2007..Cognitive deficits are associated with posttraumatic stress disorder (PTSD), but whether such deficits reflect sequelae or risk factors is not fully resolved... - A twin study of depression symptoms, hypertension, and heart disease in middle-aged menJeffrey F Scherrer
School of Public Health, St Louis University Health Sciences Center, Missouri, USA
Psychosom Med 65:548-57. 2003..We utilized a twin design to test whether there are common genetic and environmental risk factors underlying depression symptoms, hypertension and heart disease... - Leflunomide use during the first 33 months after food and drug administration approval: experience with a national cohort of 3,325 patientsChokkalingam Siva
St. Louis VAMC (151C) and Washington University School of Medicine, 915 North Grand, St. Louis, MO 63106, USA
Arthritis Rheum 49:745-51. 2003..CONCLUSION: LEF is relatively safe in clinical practice. The VA's national databases provide an excellent, inexpensive resource for postmarketing evaluation of rheumatologic medications... - A twin study of sexual behavior in menMichael J Lyons
Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
Arch Sex Behav 33:129-36. 2004..The data suggest that the observed association between age of initiation of sexual relations and having multiple partners is due to genetic influences common to both behaviors... - A twin registry study of familial and individual risk factors for trauma exposure and posttraumatic stress disorderKarestan C Koenen
Division of Epidemiology, Mailman School of Public Health, Columbia University, PH-18-EPI, 600 West 168th Street, New York, New York 10032, USA
J Nerv Ment Dis 190:209-18. 2002..Results suggest the association of familial psychopathology and PTSD may be mediated by increased risk of traumatic exposure and by preexisting psychopathology... - Lifetime and 12-month prevalence of psychiatric disorders in 8,169 male Vietnam War era veteransSeth A Eisen
Research and Medical Service, Department of Veteran Affairs Medical Center, St. Louis, MO 63106, USA
Mil Med 169:896-902. 2004.... - Shared genetic contributions to pathological gambling and major depression in menMarc N Potenza
Department of Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, New Haven, CT 06519, USA
Arch Gen Psychiatry 62:1015-21. 2005..Although pathological gambling (PG) and major depression (MD) frequently co-occur, little is known regarding the relative contributions of environmental and genetic factors to the codevelopment of the disorders... - Juvenile conduct disorder as a risk factor for trauma exposure and posttraumatic stress disorderKarestan C Koenen
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
J Trauma Stress 18:23-32. 2005..The findings suggest CD increases risk for trauma exposure and PTSD among male veterans through direct and indirect mechanisms. Veterans who have a history of CD are at high risk for trauma exposure and development of PTSD... - Posttraumatic stress disorder and late-onset smoking in the Vietnam era twin registryKarestan C Koenen
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, and The Miriam Hospital, Providence, RI, USA
J Consult Clin Psychol 74:186-90. 2006..If replicated, these results identify PTSD as a risk factor for smoking that should lead to early tobacco control treatment in this population... - Genes, environment, and time: the Vietnam Era Twin Study of Aging (VETSA)William S Kremen
Department of Psychiatry, University of California-San Diego, San Diego, CA, USA
Twin Res Hum Genet 9:1009-22. 2006.... - A twin study of the neuropsychological consequences of stimulant abuseRosemary Toomey
Department of Psychiatry, Massachusetts Mental Health Center, Harvard Medical School, 02129, USA
Arch Gen Psychiatry 60:303-10. 2003..Previous studies document neuropsychological deficits associated with stimulant abuse, but findings are inconsistent...