B P Nathan

Summary

Affiliation: Eastern Illinois University
Country: USA

Publications

  1. ncbi request reprint Apolipoprotein E is upregulated in olfactory bulb glia following peripheral receptor lesion in mice
    B P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, Illinois 61920, USA
    Exp Neurol 172:128-36. 2001
  2. ncbi request reprint Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Brain Res 928:96-105. 2002
  3. ncbi request reprint Olfactory function in apoE knockout mice
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Behav Brain Res 150:1-7. 2004
  4. ncbi request reprint Delayed olfactory nerve regeneration in ApoE-deficient mice
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Brain Res 1041:87-94. 2005
  5. ncbi request reprint Estradiol replacement increases the low-density lipoprotein receptor related protein (LRP) in the mouse brain
    Xiangying Cheng
    Center for Alzheimer s Disease and Related Disorders, Department of Neurology, Southern Illinois University School of Medicine, P O Box 19643, Springfield, IL 62794 9643, USA
    Neurosci Lett 417:50-4. 2007
  6. pmc The distribution of apolipoprotein E in mouse olfactory epithelium
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Brain Res 1137:78-83. 2007
  7. ncbi request reprint Estradiol regulation of astroglia and apolipoprotein E: an important role in neuronal regeneration
    Robert G Struble
    Department of Neurology and Center for Alzheimer Disease, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    Exp Gerontol 42:54-63. 2007
  8. pmc Impact of apoE deficiency during synaptic remodeling in the mouse olfactory bulb
    Ikemefuna Nwosu
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, United States
    Neurosci Lett 441:282-5. 2008
  9. ncbi request reprint Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, Charleston, Illinois 61920, USA
    Endocrinology 145:3065-73. 2004
  10. ncbi request reprint Apolipoprotein E may be a critical factor in hormone therapy neuroprotection
    Robert G Struble
    Center for Alzheimer s Disease and Related Disorders, Department of Neurology, Southern Illinois University School of Medicine, P O Box 19643, Springfield, IL 62794 9643, USA
    Front Biosci 13:5387-405. 2008

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Apolipoprotein E is upregulated in olfactory bulb glia following peripheral receptor lesion in mice
    B P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, Illinois 61920, USA
    Exp Neurol 172:128-36. 2001
    ..The association of apoE genotype with dementing illnesses may represent a diminished ability to support a lifetime of nerve regeneration...
  2. ncbi request reprint Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Brain Res 928:96-105. 2002
    ..These data suggest a potential mechanism whereby apoE4 may play a role in regenerative failure and accelerate the development of AD...
  3. ncbi request reprint Olfactory function in apoE knockout mice
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Behav Brain Res 150:1-7. 2004
    ..These data demonstrate that apoE deficiency in apoE KO mice leads to a deficit in olfactory function, suggesting an important role for apoE in the olfactory system...
  4. ncbi request reprint Delayed olfactory nerve regeneration in ApoE-deficient mice
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Brain Res 1041:87-94. 2005
    ..Together, these results show that olfactory nerve regeneration is significantly slower in KO mice as compared to WT mice, suggesting apoE facilitates olfactory nerve regeneration...
  5. ncbi request reprint Estradiol replacement increases the low-density lipoprotein receptor related protein (LRP) in the mouse brain
    Xiangying Cheng
    Center for Alzheimer s Disease and Related Disorders, Department of Neurology, Southern Illinois University School of Medicine, P O Box 19643, Springfield, IL 62794 9643, USA
    Neurosci Lett 417:50-4. 2007
    ..In contrast, E2 treatment decreased LDL-r protein expression in olfactory bulb. HT modification of both apoE and LRP could have wide-spread effects on cellular function given LRP's manifold signaling functions...
  6. pmc The distribution of apolipoprotein E in mouse olfactory epithelium
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, USA
    Brain Res 1137:78-83. 2007
    ....
  7. ncbi request reprint Estradiol regulation of astroglia and apolipoprotein E: an important role in neuronal regeneration
    Robert G Struble
    Department of Neurology and Center for Alzheimer Disease, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    Exp Gerontol 42:54-63. 2007
    ..Moreover, the role of glial-derived proteins in neuroprotection should not be ignored...
  8. pmc Impact of apoE deficiency during synaptic remodeling in the mouse olfactory bulb
    Ikemefuna Nwosu
    Department of Biological Sciences, Eastern Illinois University, 600 Lincoln Avenue, Charleston, IL 61920, United States
    Neurosci Lett 441:282-5. 2008
    ..The data indicate that apoE deficiency in KO mice is associated with a delayed recovery of the glomerular area and a slower recovery in Syn concentration in the OB...
  9. ncbi request reprint Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons
    Britto P Nathan
    Department of Biological Sciences, Eastern Illinois University, Charleston, Illinois 61920, USA
    Endocrinology 145:3065-73. 2004
    ..The effects of ERT on chronic neurological diseases may vary with ApoE genotype. The clinical use of ERT may require ApoE genotyping for optimal efficacy...
  10. ncbi request reprint Apolipoprotein E may be a critical factor in hormone therapy neuroprotection
    Robert G Struble
    Center for Alzheimer s Disease and Related Disorders, Department of Neurology, Southern Illinois University School of Medicine, P O Box 19643, Springfield, IL 62794 9643, USA
    Front Biosci 13:5387-405. 2008
    ..Future studies of HT should evaluate the effects of apoE genotype and production estradiol on neuroprotection...
  11. ncbi request reprint Time course of response to estradiol replacement in ovariectomized mice: brain apolipoprotein E and synaptophysin transiently increase and glial fibrillary acidic protein is suppressed
    Mary E McAsey
    Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794 9672, USA
    Exp Neurol 197:197-205. 2006
    ..These observations suggest that estradiol is able to suppress reactive gliosis. In addition, E2 replacement in OVX mice is associated with transiently higher levels of apoE and synaptophysin...