Laura K Hanson

Summary

Affiliation: Eastern Virginia Medical School
Country: USA

Publications

  1. ncbi request reprint Characterization and regulation of essential murine cytomegalovirus genes m142 and m143
    Laura K Hanson
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Virology 334:166-77. 2005
  2. pmc Murine cytomegalovirus US22 protein pM140 protects its binding partner, pM141, from proteasome-dependent but ubiquitin-independent degradation
    Lisa L Bolin
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, 700 W Olney Rd, P O Box 1980, Norfolk, VA 23501, USA
    J Virol 84:2164-8. 2010
  3. pmc Murine cytomegalovirus capsid assembly is dependent on US22 family gene M140 in infected macrophages
    Laura K Hanson
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    J Virol 83:7449-56. 2009
  4. pmc Complex formation among murine cytomegalovirus US22 proteins encoded by genes M139, M140, and M141
    Zaruhi Karabekian
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, 700 W Olney Rd, Norfolk, VA 23507, USA
    J Virol 79:3525-35. 2005
  5. pmc Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals
    Margaret J Wortman
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, 700 W, Olney Road, Norfolk, VA 23507, USA
    BMC Mol Biol 11:81. 2010
  6. pmc Double-stranded RNA binding by a heterodimeric complex of murine cytomegalovirus m142 and m143 proteins
    Stephanie J Child
    Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, MS C2 023, Seattle, WA 98109 1024, USA
    J Virol 80:10173-80. 2006

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Characterization and regulation of essential murine cytomegalovirus genes m142 and m143
    Laura K Hanson
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Virology 334:166-77. 2005
    ..This failure to transactivate, along with their essential nature, makes m142 and m143 unique among the immediate-early genes of the US22 gene family...
  2. pmc Murine cytomegalovirus US22 protein pM140 protects its binding partner, pM141, from proteasome-dependent but ubiquitin-independent degradation
    Lisa L Bolin
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, 700 W Olney Rd, P O Box 1980, Norfolk, VA 23501, USA
    J Virol 84:2164-8. 2010
    ..The M140 protein thus contains multiple domains that collectively confer a structure necessary to function in virion assembly in macrophages...
  3. pmc Murine cytomegalovirus capsid assembly is dependent on US22 family gene M140 in infected macrophages
    Laura K Hanson
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    J Virol 83:7449-56. 2009
    ..It appears, therefore, that pM140 indirectly influences MCMV capsid formation in differentiated macrophages by regulating the stability of viral structural proteins...
  4. pmc Complex formation among murine cytomegalovirus US22 proteins encoded by genes M139, M140, and M141
    Zaruhi Karabekian
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, 700 W Olney Rd, Norfolk, VA 23507, USA
    J Virol 79:3525-35. 2005
    ..Thus, complexing of these nonessential, early MCMV proteins likely confers a function(s) independent of each individual protein and important for optimal replication of MCMV in its natural host...
  5. pmc Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals
    Margaret J Wortman
    Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, 700 W, Olney Road, Norfolk, VA 23507, USA
    BMC Mol Biol 11:81. 2010
    ..The distinct but related roles of PurĪ± suggest a need for expression regulated differently depending on intracellular and external signals...
  6. pmc Double-stranded RNA binding by a heterodimeric complex of murine cytomegalovirus m142 and m143 proteins
    Stephanie J Child
    Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, MS C2 023, Seattle, WA 98109 1024, USA
    J Virol 80:10173-80. 2006
    ..However, unlike other well-studied examples, the MCMV proteins appear to act in a heterodimeric complex...