Roger Gosden

Summary

Affiliation: Eastern Virginia Medical School
Country: USA

Publications

  1. ncbi request reprint Fertility after intact ovary transplantation
    Xiang Wang
    Laboratory of Experimental Surgery, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Quebec H2L 4M1, Canada
    Nature 415:385. 2002
  2. ncbi request reprint Rare congenital disorders, imprinted genes, and assisted reproductive technology
    Roger Gosden
    The Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Lancet 361:1975-7. 2003
  3. ncbi request reprint Preservation of fertility in nature and ART
    Roger Gosden
    Department of Obstetrics and Gynecology, McGill University, Montreal, Canada
    Reproduction 123:3-11. 2002
  4. ncbi request reprint Current perspective on primordial follicle cryopreservation and culture for reproductive medicine
    Roger G Gosden
    Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
    Hum Reprod Update 8:105-10. 2002
  5. ncbi request reprint Germline stem cells in the postnatal ovary: is the ovary more like a testis?
    Roger G Gosden
    The Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, 601 Colley Avenue, Norfolk, VA 23507, USA
    Hum Reprod Update 10:193-5. 2004
  6. ncbi request reprint Should ICSI be the treatment of choice for all cases of in-vitro conception? No, not in light of the scientific data
    Sergio Oehninger
    The Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, VA, USA
    Hum Reprod 17:2237-42. 2002
  7. ncbi request reprint Transplantation of intact rat gonads using vascular anastomosis: effects of cryopreservation, ischaemia and genotype
    Hang Yin
    Department of Obstetrics and Gynecology, McGill University, Royal Victoria Hospital, Montreal, QC H3A 1A1, Canada
    Hum Reprod 18:1165-72. 2003
  8. ncbi request reprint Murine homologues of the Drosophila gustavus gene are expressed in ovarian granulosa cells
    Yan Xing
    Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
    Reproduction 131:905-15. 2006
  9. ncbi request reprint Continuous loss of oocytes throughout meiotic prophase in the normal mouse ovary
    Kelly A McClellan
    Department of Biology, McGill University, H3A 1B1, Montreal, Quebec, Canada
    Dev Biol 258:334-48. 2003
  10. pmc Comparative maturation of cynomolgus monkey oocytes in vivo and in vitro
    Hang Yin
    The Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynaecology Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Reprod Biol Endocrinol 4:14. 2006

Detail Information

Publications21

  1. ncbi request reprint Fertility after intact ovary transplantation
    Xiang Wang
    Laboratory of Experimental Surgery, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Quebec H2L 4M1, Canada
    Nature 415:385. 2002
    ..Here we describe the successful transplantation in rats of ovaries, fallopian tubes and the upper segment of the uterus en bloc after storage in liquid nitrogen...
  2. ncbi request reprint Rare congenital disorders, imprinted genes, and assisted reproductive technology
    Roger Gosden
    The Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Lancet 361:1975-7. 2003
    ..In general, the incidence of abnormalities at birth is reassuringly low and children develop normally. Nevertheless, it is important to monitor the safety of ARTs as clinical protocols evolve and new technologies emerge...
  3. ncbi request reprint Preservation of fertility in nature and ART
    Roger Gosden
    Department of Obstetrics and Gynecology, McGill University, Montreal, Canada
    Reproduction 123:3-11. 2002
    ....
  4. ncbi request reprint Current perspective on primordial follicle cryopreservation and culture for reproductive medicine
    Roger G Gosden
    Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
    Hum Reprod Update 8:105-10. 2002
    ..Achievement of this goal for the larger and more slowly developing follicles from human and farm animal ovaries is still a remote possibility...
  5. ncbi request reprint Germline stem cells in the postnatal ovary: is the ovary more like a testis?
    Roger G Gosden
    The Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, 601 Colley Avenue, Norfolk, VA 23507, USA
    Hum Reprod Update 10:193-5. 2004
  6. ncbi request reprint Should ICSI be the treatment of choice for all cases of in-vitro conception? No, not in light of the scientific data
    Sergio Oehninger
    The Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, VA, USA
    Hum Reprod 17:2237-42. 2002
    ..A better definition of the indications for ICSI is needed, together with the development of directed, simpler, less expensive and safer alternatives...
  7. ncbi request reprint Transplantation of intact rat gonads using vascular anastomosis: effects of cryopreservation, ischaemia and genotype
    Hang Yin
    Department of Obstetrics and Gynecology, McGill University, Royal Victoria Hospital, Montreal, QC H3A 1A1, Canada
    Hum Reprod 18:1165-72. 2003
    ..To maximize gonadal function, it is desirable to preserve whole gonads for transplantation using vascular anastomosis...
  8. ncbi request reprint Murine homologues of the Drosophila gustavus gene are expressed in ovarian granulosa cells
    Yan Xing
    Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
    Reproduction 131:905-15. 2006
    ..Based on their tissue-restricted pattern of expression and apparent abundance in granulosa cells, we propose that SSB-1 and SSB-4 play key roles in regulating granulosa cell physiology...
  9. ncbi request reprint Continuous loss of oocytes throughout meiotic prophase in the normal mouse ovary
    Kelly A McClellan
    Department of Biology, McGill University, H3A 1B1, Montreal, Quebec, Canada
    Dev Biol 258:334-48. 2003
    ..These observations suggest that multiple causes are responsible for oocyte elimination...
  10. pmc Comparative maturation of cynomolgus monkey oocytes in vivo and in vitro
    Hang Yin
    The Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynaecology Eastern Virginia Medical School, Norfolk, VA 23507, USA
    Reprod Biol Endocrinol 4:14. 2006
    ....
  11. ncbi request reprint Prospect of preimplantation genetic diagnosis for heritable mitochondrial DNA diseases
    Nicola L Dean
    Department of Obstetrics and Gynecology, Royal Victoria Hospital, Montreal, H3A 1A1, Quebec, Canada
    Mol Hum Reprod 9:631-8. 2003
    ..We conclude that preimplantation genetic diagnosis is feasible for mtDNA diseases, although it should be approached with caution, as it is possible that transmission of some pathogenic mutations could behave in a different manner...
  12. ncbi request reprint Application of traditional Chinese medicine in the treatment of infertility
    Xian Xu
    The Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynaecology, Norfolk, VA 23507, USA
    Hum Fertil (Camb) 6:161-8. 2003
    ..However, the task is enormous in view of the number of herbal products currently available on the market; yet among these products are undoubtedly some that will prove to be safe and beneficial...
  13. ncbi request reprint Survival of ovarian allografts in an experimental animal model
    Roger G Gosden
    Center for Reproductive Medicine and Infertility, Weill Medical College of Cornell University, New York, NY 10021, USA
    Pediatr Transplant 11:628-33. 2007
    ..These results indicate that the ovary is not an immunologically privileged organ, as the older literature suggested, and chronic immunosuppression is likely to be required for ovarian allografts in clinical settings...
  14. ncbi request reprint Carbohydrate metabolism by murine ovarian follicles and oocytes grown in vitro
    Sarah E Harris
    Reproduction and Early Development Research Group, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds LS2 9JT, UK
    Reproduction 134:415-24. 2007
    ..Additionally, the metabolic profiles of in vitro produced OCCs and the oocytes within them are affected by long-term exposure to the culture environment...
  15. ncbi request reprint Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells
    James Adjaye
    Max Planck Institute for Molecular Genetics Department of Vertebrate Genomics, Ihnestrasse 73, D 14195 Berlin, Germany
    Stem Cells 23:1514-25. 2005
    ..These data enhance our understanding of the first step in human cellular differentiation and, hence, the derivation of both embryonic stem cells and trophoblastic stem cells from these lineages...
  16. ncbi request reprint On regenerating the ovary and generating controversy
    Evelyn E Telfer
    Cell 122:821-2. 2005
  17. ncbi request reprint Ovarian transplantation between monozygotic twins discordant for premature ovarian failure
    Sherman J Silber
    Infertility Center of St Louis, St Luke s Hospital, St Louis, MO 63017, USA
    N Engl J Med 353:58-63. 2005
    ..During the second cycle, she conceived, and her pregnancy progressed uneventfully. At 38 weeks' gestation, she delivered a healthy-appearing female infant...
  18. ncbi request reprint Quantitative assessment of ischemic tissue damage in ovarian cortical tissue with or without antioxidant (ascorbic acid) treatment
    S Samuel Kim
    Eulji Life Science Institute, Eulji University School of Medicine, Seoul, South Korea
    Fertil Steril 82:679-85. 2004
    ..To estimate ischemic tissue damage in ovarian cortex and to evaluate the effectiveness of ascorbic acid, an antioxidant, to protect ovarian tissue from apoptosis caused by ischemia...
  19. ncbi request reprint Genetics and epigenetics--nature's pen-and-pencil set
    Roger G Gosden
    N Engl J Med 356:731-3. 2007
  20. ncbi request reprint Ovarian transplantation in a series of monozygotic twins discordant for ovarian failure
    Sherman J Silber
    N Engl J Med 356:1382-4. 2007
  21. ncbi request reprint Ovarian aging in two species of long-lived rockfish, Sebastes aleutianus and S. alutus
    Jan Peter de Bruin
    Andrus Gerontology Center and Department of Biological Sciences, University of Southern California, Los Angeles, California 90089, USA
    Biol Reprod 71:1036-42. 2004
    ..These species represent an iteroparous extreme in the spectrum of life history strategies and merit investigation to determine the mechanisms for such an extended reproductive life span...