KENJI MASON CUNNION

Summary

Affiliation: Eastern Virginia Medical School
Country: USA

Publications

  1. ncbi Availability of complement bound to Staphylococcus aureus to interact with membrane complement receptors influences efficiency of phagocytosis
    K M Cunnion
    Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Infect Immun 71:656-62. 2003
  2. ncbi Complement activation influences Staphylococcus aureus adherence to endothelial cells
    K M Cunnion
    Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Infect Immun 71:1321-7. 2003
  3. ncbi Cleavage of complement C3b to iC3b on the surface of Staphylococcus aureus is mediated by serum complement factor I
    K M Cunnion
    Center for Pediatric Research, Eastern Virginia Medical School and Children s Hospital for The King s Daughters, Norfolk, Virginia 23510, USA
    Infect Immun 72:2858-63. 2004
  4. ncbi Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia
    Kenji M Cunnion
    Department of Pediatrics and Duke Clinical Research Institue, Duke University Medical Center, Durham, NC, USA
    J Lab Clin Med 143:358-65. 2004
  5. ncbi Serum complement factor I decreases Staphylococcus aureus phagocytosis
    Kenji M Cunnion
    Department of Pediatrics, Eastern Virginia Medical School and Children s Hospital of The King s Daughters, Norfolk, USA
    J Lab Clin Med 146:279-86. 2005

Research Grants

  1. Complement and the Clearance of Staphylococcus aureus
    KENJI CUNNION; Fiscal Year: 2006

Detail Information

Publications5

  1. ncbi Availability of complement bound to Staphylococcus aureus to interact with membrane complement receptors influences efficiency of phagocytosis
    K M Cunnion
    Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Infect Immun 71:656-62. 2003
    ..aureus was not increased...
  2. ncbi Complement activation influences Staphylococcus aureus adherence to endothelial cells
    K M Cunnion
    Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Infect Immun 71:1321-7. 2003
    ..aureus was 234% higher than that of EC exposed to NHS. Thus, complement-activated EC have increased S. aureus binding, while complement on the bacterial surface markedly reduces adherence...
  3. ncbi Cleavage of complement C3b to iC3b on the surface of Staphylococcus aureus is mediated by serum complement factor I
    K M Cunnion
    Center for Pediatric Research, Eastern Virginia Medical School and Children s Hospital for The King s Daughters, Norfolk, Virginia 23510, USA
    Infect Immun 72:2858-63. 2004
    ..Purified factor H, a serum protein cofactor for factor I, did not enhance factor I-mediated cleavage of C3b. These findings suggest that C3b cleavage to iC3b on S. aureus is mediated by serum factor I and does not require factor H...
  4. ncbi Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia
    Kenji M Cunnion
    Department of Pediatrics and Duke Clinical Research Institue, Duke University Medical Center, Durham, NC, USA
    J Lab Clin Med 143:358-65. 2004
    ..Mice deficient in CD35/CD21 showed a 67% decrease in survival compared with normal mice, suggesting that CD35/CD21 is of major importance in the control of S aureus-induced bacteremia...
  5. ncbi Serum complement factor I decreases Staphylococcus aureus phagocytosis
    Kenji M Cunnion
    Department of Pediatrics, Eastern Virginia Medical School and Children s Hospital of The King s Daughters, Norfolk, USA
    J Lab Clin Med 146:279-86. 2005
    ..aureus surface, and thereby enhancing opsonophagocytosis, is a promising potential target for therapeutic intervention...

Research Grants1

  1. Complement and the Clearance of Staphylococcus aureus
    KENJI CUNNION; Fiscal Year: 2006
    ..In vivo experiments will be performed using complement deficient mice. Collaborating laboratories have provided special S. aureus stains and anti-S. aureus antibodies. ..