Ke Sheng Wang

Summary

Affiliation: East Tennessee State University
Country: USA

Publications

  1. doi request reprint A novel locus for body mass index on 5p15.2: a meta-analysis of two genome-wide association studies
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, East Tennessee State University, Johnson City, TN 37614, USA
    Gene 500:80-4. 2012
  2. doi request reprint NRG3 gene is associated with the risk and age at onset of Alzheimer disease
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN, 37614 1700, USA
    J Neural Transm 121:183-92. 2014
  3. ncbi request reprint Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene x gender interaction
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, P O Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Genet 92:395-402. 2013
  4. ncbi request reprint Genetic association analysis of ITGB3 polymorphisms with age at onset of schizophrenia
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN, 37614 1700, USA
    J Mol Neurosci 51:446-53. 2013
  5. doi request reprint ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614, USA
    Drug Alcohol Depend 124:325-32. 2012
  6. doi request reprint PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614 1700, USA
    J Mol Neurosci 48:265-72. 2012
  7. doi request reprint Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614 1700, USA
    J Neural Transm 119:425-33. 2012
  8. doi request reprint Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN, 37614 1700, USA
    J Mol Neurosci 46:265-71. 2012
  9. pmc Parent-of-origin effects of FAS and PDLIM1 in attention-deficit/hyperactivity disorder
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Psychiatry Neurosci 37:46-52. 2012
  10. ncbi request reprint Family-based association analysis of the MAPT gene in Parkinson disease
    K S Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Appl Genet 51:509-14. 2010

Collaborators

Detail Information

Publications21

  1. doi request reprint A novel locus for body mass index on 5p15.2: a meta-analysis of two genome-wide association studies
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, East Tennessee State University, Johnson City, TN 37614, USA
    Gene 500:80-4. 2012
    ..Genetic factors play an important role in modulating the vulnerability to body mass index (BMI). The purpose of this study is to identify novel genetic variants for BMI using genome-wide association (GWA) meta-analysis...
  2. doi request reprint NRG3 gene is associated with the risk and age at onset of Alzheimer disease
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN, 37614 1700, USA
    J Neural Transm 121:183-92. 2014
    ..05). This is the first study demonstrating that genetic variants in the NRG3 gene play a role in AD. Our results also revealed that SNPs in the NRG3 genes were more strongly associated with AAO of AD. ..
  3. ncbi request reprint Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene x gender interaction
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, P O Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Genet 92:395-402. 2013
    ..000625) for triglycerides in the Marshfield sample. These findings contribute new insights into the pathogenesis of obesity and triglycerides and demonstrate the importance of gender differences in the aetiology. ..
  4. ncbi request reprint Genetic association analysis of ITGB3 polymorphisms with age at onset of schizophrenia
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN, 37614 1700, USA
    J Mol Neurosci 51:446-53. 2013
    ..This is the first report which shows that ITGB3 variants are associated with AAO in SCZ, providing direct evidence of the use of AAO as an intermediate phenotype to dissect the complex genetics of SCZ...
  5. doi request reprint ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614, USA
    Drug Alcohol Depend 124:325-32. 2012
    ..In conclusion, we identified several loci associated with ND through meta-analysis of two GWA studies. These findings offer the potential for new insights into the pathogenesis of ND...
  6. doi request reprint PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614 1700, USA
    J Mol Neurosci 48:265-72. 2012
    ..12 × 10(-5)). In conclusion, we identified four new loci (PKNOX2, MYH13, PHF2, and GPC6) associated with FTD. These findings offer the potential for new insights into the pathogenesis of FTD and schizophrenia...
  7. doi request reprint Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614 1700, USA
    J Neural Transm 119:425-33. 2012
    ..In conclusion, we identified several loci associated with AWS. These findings offer the potential for new insights into the pathogenesis of AD and AWS...
  8. doi request reprint Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN, 37614 1700, USA
    J Mol Neurosci 46:265-71. 2012
    ..In addition, the association of rs727532 with AD was confirmed in a replication study. This study reports some newly recognized associations between several genetic loci and both AD and three personality traits...
  9. pmc Parent-of-origin effects of FAS and PDLIM1 in attention-deficit/hyperactivity disorder
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Psychiatry Neurosci 37:46-52. 2012
    ..The objective of the present study was to investigate parent-of-origin effects using a genome-wide association analysis of the International Multicentre ADHD Genetics (IMAGE) study sample...
  10. ncbi request reprint Family-based association analysis of the MAPT gene in Parkinson disease
    K S Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Appl Genet 51:509-14. 2010
    ..021, respectively). Two-SNP haplotypes inferred from rs17563965 and rs17649641 also showed association with PD (P = 0.018) and age at onset (P = 0.026). These results provide further support for the role of MAPT in development of PD...
  11. doi request reprint A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614, USA
    Schizophr Res 124:192-9. 2010
    ..These findings will serve as a resource for replication in other populations to elucidate the potential role of these genetic variants in schizophrenia and bipolar disorder...
  12. doi request reprint Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Neural Transm 118:1293-9. 2011
    ..These findings offer the potential for new insights into the pathogenesis of AD and will serve as a resource for replication in other populations to elucidate the potential role of these genetic variants in AD...
  13. doi request reprint A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614, USA
    J Psychiatr Res 45:1419-25. 2011
    ..These findings offer the potential for new insights into the pathogenesis of alcohol dependence...
  14. ncbi request reprint Genome-wide association analysis of age at onset in schizophrenia in a European-American sample
    Ke Sheng Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, 37614 1700, USA
    Am J Med Genet B Neuropsychiatr Genet 156:671-80. 2011
    ..05). These findings provide evidence of several genetic variants influencing AAO of SCZ...
  15. ncbi request reprint Genome-wide association studies of maximum number of drinks
    Yue Pan
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN, USA Department of Epidemiology and Public Health, Miller School of Medicine, University of Miami, Miami, FL, USA
    J Psychiatr Res 47:1717-24. 2013
    ..In conclusions, we identified several genes/regions associated with MaxDrinks. These findings can improve the understanding about the pathogenesis of alcohol consumption phenotypes and alcohol-related disorders...
  16. ncbi request reprint Genetic variants in the fat mass- and obesity-associated (FTO) gene are associated with alcohol dependence
    Liang Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Lamb Hall, Johnson City, TN, PO Box 70259, 37614 1700, USA
    J Mol Neurosci 51:416-24. 2013
    ..In addition, we found association of rs17817449 (which has a strong linkage disequilibrium with rs9939609) with AD in the SAGE sample (p = 0.00339). The findings provide evidence of joint intervention and prevention of AD and obesity...
  17. doi request reprint NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies
    Yue Pan
    Department of Mathematics and Statistics, College of Arts and Sciences, East Tennessee State University, Johnson City, TN 37614, USA
    Prog Neuropsychopharmacol Biol Psychiatry 35:154-60. 2011
    ..In conclusion, our findings provide evidence that chromosome regions of 11q25 and 4q31.1 contain genes affecting IQ. This study will serve as a resource for replication in other populations...
  18. doi request reprint Association of ADAM10 and CAMK2A polymorphisms with conduct disorder: evidence from family-based studies
    Xue Qiu Jian
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Abnorm Child Psychol 39:773-82. 2011
    ..Especially, the two genes (ADAM10 and CAMK2A) have been reported to be associated with Alzheimer's disease, bipolar disorder and depression. These findings may serve as a resource for replication in other populations...
  19. doi request reprint Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples
    Nagesh Aragam
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614, USA
    J Affect Disord 133:516-21. 2011
    ..While the gender differences for MDD have been widely reported in literature, few genome-wide analyses of gender differences have been reported to date...
  20. doi request reprint TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample
    Nagesh Aragam
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, PO Box 70259, Lamb Hall, Johnson City, TN 37614 1700, USA
    J Mol Neurosci 50:250-6. 2013
    ..Our findings provide a basis for replication in other populations to elucidate the potential role of these genetic variants in neuroticism and MDD along with a possible relationship between ASPD and neuroticism...
  21. doi request reprint Age differences in the associations of behavioral and psychosocial factors with stroke
    Liang Wang
    Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN 37614, USA
    Neuroepidemiology 41:94-100. 2013
    ..The aim of this study was to examine the age differences in these risk factors for stroke as young (18-44 years), middle aged (45-64 years), and elderly (65 years or older)...