Research Topics
Species | J K SmithSummaryAffiliation: East Tennessee State University Country: USA Publications
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Publications
Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart diseaseJ K Smith
Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City 37614, USA
JAMA 281:1722-7. 1999..It is not known whether long-term exercise alters this atherogenic and atheroprotective activity directly...
Interferon-alpha upregulates gene expression of aquaporin-5 in human parotid glandsJ K Smith
Department of Internal Medicine, James H Quillen College of Medicine, Johnson City, TN 37614 0622, USA
J Interferon Cytokine Res 19:929-35. 1999..We conclude that IFN-alpha upregulates AQP5 gene expression in human parotid acinar cells in vitro. To our knowledge, this is the first demonstration that IFN-alpha regulates the gene expression of an aquaporin...
Human endothelium as a source of multifunctional cytokines: molecular regulation and possible role in human diseaseG Krishnaswamy
Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City 37614 0622, USA
J Interferon Cytokine Res 19:91-104. 1999..Genetic and pharmacologic manipulation of endothelial-derived cytokines provides an additional approach to the management of chronic inflammatory diseases...
Exercise and atherogenesisJ K Smith
Division of Immunology, Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, TN 37614, USA
Exerc Sport Sci Rev 29:49-53. 2001..Exercise training contributes to the arrest and even reversal of atherosclerosis by modifying risk factors and by inducing an atheroprotective phenotype in endothelial cells and T cells...
Oral use of interferon-alpha stimulates ISG-15 transcription and production by human buccal epithelial cellsJ K Smith
Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City 37614 0622, USA
J Interferon Cytokine Res 19:923-8. 1999..We conclude that orally administered IFN-alpha exerts its immunomodulatory effects in humans in part by upregulating the production of ISG-15 by BEC, thereby enhancing the immune reactivity of mucosa-associated lymphocytes...
