MD A MOTALEB

Summary

Affiliation: East Carolina University
Country: USA

Publications

  1. pmc A novel gene inactivation system reveals altered periplasmic flagellar orientation in a Borrelia burgdorferi fliL mutant
    M A Motaleb
    Department of Microbiology and Immunology, East Carolina University, Greenville, NC 27834, USA
    J Bacteriol 193:3324-31. 2011
  2. pmc CheY3 of Borrelia burgdorferi is the key response regulator essential for chemotaxis and forms a long-lived phosphorylated intermediate
    M A Motaleb
    Department of Microbiology and Immunology, East Carolina University School of Medicine, Greenville, NC 27834, USA
    J Bacteriol 193:3332-41. 2011
  3. pmc Analysis of the Borrelia burgdorferi cyclic-di-GMP-binding protein PlzA reveals a role in motility and virulence
    Joshua E Pitzer
    Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
    Infect Immun 79:1815-25. 2011
  4. pmc Analysis of a Borrelia burgdorferi phosphodiesterase demonstrates a role for cyclic-di-guanosine monophosphate in motility and virulence
    Syed Z Sultan
    Department of Microbiology and Immunology, Brody School of Medicine, 600 Moye Boulevard, Greenville, NC 27834, USA
    Mol Microbiol 77:128-42. 2010
  5. pmc The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi
    Elizabeth A Novak
    Department of Microbiology and Immunology, East Carolina University Brody School of Medicine Greenville, NC, USA
    Front Cell Infect Microbiol 4:56. 2014
  6. pmc Analysis of the HD-GYP domain cyclic dimeric GMP phosphodiesterase reveals a role in motility and the enzootic life cycle of Borrelia burgdorferi
    Syed Z Sultan
    Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
    Infect Immun 79:3273-83. 2011

Collaborators

Detail Information

Publications6

  1. pmc A novel gene inactivation system reveals altered periplasmic flagellar orientation in a Borrelia burgdorferi fliL mutant
    M A Motaleb
    Department of Microbiology and Immunology, East Carolina University, Greenville, NC 27834, USA
    J Bacteriol 193:3324-31. 2011
    ..Our results suggest that FliL is likely involved in coordinating or regulating the orientation of periplasmic flagella in B. burgdorferi...
  2. pmc CheY3 of Borrelia burgdorferi is the key response regulator essential for chemotaxis and forms a long-lived phosphorylated intermediate
    M A Motaleb
    Department of Microbiology and Immunology, East Carolina University School of Medicine, Greenville, NC 27834, USA
    J Bacteriol 193:3332-41. 2011
    ..The results point toward CheY3 being the key response regulator essential for chemotaxis in B. burgdorferi. In addition, the stability of CheY3-P may be critical for coordination of the rotation of the periplasmic flagella...
  3. pmc Analysis of the Borrelia burgdorferi cyclic-di-GMP-binding protein PlzA reveals a role in motility and virulence
    Joshua E Pitzer
    Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
    Infect Immun 79:1815-25. 2011
    ..burgdorferi enzootic life cycle cannot yet be excluded...
  4. pmc Analysis of a Borrelia burgdorferi phosphodiesterase demonstrates a role for cyclic-di-guanosine monophosphate in motility and virulence
    Syed Z Sultan
    Department of Microbiology and Immunology, Brody School of Medicine, 600 Moye Boulevard, Greenville, NC 27834, USA
    Mol Microbiol 77:128-42. 2010
    ..These results reveal an important connection between cyclic-di-GMP, B. burgdorferi motility and Lyme disease pathogenesis. A mechanism by which cyclic-di-GMP influences motility and infection is proposed...
  5. pmc The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi
    Elizabeth A Novak
    Department of Microbiology and Immunology, East Carolina University Brody School of Medicine Greenville, NC, USA
    Front Cell Infect Microbiol 4:56. 2014
    ..burgdorferi during the enzootic cycle, thereby enabling the development of effective drugs for the prevention and/or treatment of Lyme disease. ..
  6. pmc Analysis of the HD-GYP domain cyclic dimeric GMP phosphodiesterase reveals a role in motility and the enzootic life cycle of Borrelia burgdorferi
    Syed Z Sultan
    Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
    Infect Immun 79:3273-83. 2011
    ..All of these phenotypes were restored when the mutant was complemented. Identification of this role of pdeB increases our understanding of the c-di-GMP signaling network in motility regulation and the life cycle of B. burgdorferi...