Research Topics
| Brian A McMillenSummaryAffiliation: East Carolina University Country: USA Publications
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Publications
Nicotine increases FosB expression within a subset of reward- and memory-related brain regions during both peri- and post-adolescenceKen Soderstrom
Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
Psychopharmacology (Berl) 191:891-7. 2007....
Effect of DOV 102,677 on the volitional consumption of ethanol by Myers' high ethanol-preferring ratBrian A McMillen
Department of Pharmacology and Toxicology, Brody School of Medicine at East Carolina University, Greenville, North Carolina 27858 4354, USA
Alcohol Clin Exp Res 31:1866-71. 2007..Therefore, the inhibitor of norepinephrine, serotonin and dopamine uptake, DOV 102,677, was tested for its effects on the volitional consumption of ethanol by an ethanol-preferring rat strain...
Effects of NMDA glutamate receptor antagonist drugs on the volitional consumption of ethanol by a genetic drinking ratBrian A McMillen
Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, USA
Brain Res Bull 64:279-84. 2004..This interaction should be explored further for its therapeutic potential and to better understand the control by central neuronal systems of the consumption of ethanol...
Periadolescent nicotine exposure causes heterologous sensitization to cocaine reinforcementBrian A McMillen
Department of Pharmacology and Toxicology, Brody School of Medicine at East Carolina University, Greenville, North Carolina 27834 USA
Eur J Pharmacol 509:161-4. 2005..0 mg/kg i.p. cocaine increased time in drug-paired chambers by 50% in control rats and 94% in nicotine-exposed animals. Thus, periadolescent nicotine exposure produced long-term sensitization to an indirect-acting dopamine agonist...
Effects of a metabotropic, mglu5, glutamate receptor antagonist on ethanol consumption by genetic drinking ratsBrian A McMillen
Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC 27858, USA
Alcohol Alcohol 40:494-7. 2005..To compare the effect of an antagonist of the mGlu5 glutamate receptor, 2-methyl-6-(phenylethynyl)pyridine (MPEP) on a test for anxiety and on the volitional consumption of ethanol...
Periadolescent nicotine exposure produces sensitization to reinforcement by diazepam in the ratNissa L James Walke
Brody School of Medicine at East Carolina University, Department of Pharmacology and Toxicology, 600 Moye Blvd, Greenville, NC 27834, USA
Neurotoxicol Teratol 29:31-6. 2007..This study supports a relationship between periadolescent nicotine priming and the production of persistent, behavioral adaptations in the young adult animal...
Effects of the non-competitive NMDA receptor antagonist memantine on the volitional consumption of ethanol by alcohol-preferring ratsGloria E Malpass
Department of Pharmacology and Toxicology, Brody School of Medicine at East Carolina University, Greenville, NC 27834, USA
Basic Clin Pharmacol Toxicol 106:435-44. 2010..In conclusion, memantine may decrease ethanol consumption with fewer side effects than other NMDA receptor antagonists, such as phencyclidine (PCP), MK 801 and ketamine...
The effect of oral consumption of perchlorate, alone and in combination with ethanol, on plasma thyroid hormone and brain catecholamine concentrations in the ratNissa L James-Walke
Brody School of Medicine, East Carolina University, Department of Pharmacology and Toxicology, 600 Moye Blvd, Greenville, NC 27834, USA
Basic Clin Pharmacol Toxicol 99:340-5. 2006..The data suggest that the no-observed effect level of perchlorate consumption on thyroid hormone and brain catecholamine concentrations is above the 3000 microg/l concentration in the adult female rat...
On the role of monoamine oxidase-A for the maintenance of the volitional consumption of ethanol in two different rat modelsBenjamin T Mega
Department of Pharmacology, Center for Alcohol and Drug Abuse Studies, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27858, USA
Naunyn Schmiedebergs Arch Pharmacol 366:319-26. 2002....
Conditioned taste aversion and the Myers' high-ethanol-preferring ratLou Anne C Lucas
Center for Alcohol and Drug Abuse Studies and Department of Pharmacology, Brody School of Medicine, East Carolina University, Greenville, NC 27858, USA
Alcohol Alcohol 37:427-31. 2002..The female mHEP rats did not learn an aversion to either saccharin or ethanol. CONCLUSIONS: The female mHEP rat consumes copious amounts of ethanol, but the basis for this consumption may be different from that of the male mHEP rat...
College students' responses to a 5/4 drinking question and maximum blood alcohol concentration calculated from a timeline followback questionnaireBrian A McMillen
Department of Pharmacology and Toxicology, Brody School of Medicine at East Carolina University, Greenville, North Carolina 27858, USA
J Stud Alcohol Drugs 70:601-5. 2009..However, some researchers have questioned the predictive validity of the 5/4 measure. This study tested whether such students attained extremely high blood alcohol concentrations (BACs) during the previous 30 days...
