Affiliation: East Carolina University
- Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKsZhenhua Guo
Department of Biology, East Carolina University, Howell Science Complex N 108, Greenville, NC 27858, USA
BMC Genomics 5:69. 2004..Moreover, although the functions of most CDKs are reasonably well studied in mammals and yeasts, very little is known from most other eukaryotes...
- Comparative genomics and evolution of proteins associated with RNA polymerase II C-terminal domainZhenhua Guo
Howell Science Complex N108, Department of Biology, East Carolina University, USA
Mol Biol Evol 22:2166-78. 2005..These constraints complicate efforts to determine orthologous gene relationships and can mislead phylogenetic and informatic algorithms...
- Connecting mutations of the RNA polymerase II C-terminal domain to complex phenotypic changes using combined gene expression and network analysesCarlyle Rogers
Department of Biology, East Carolina University, Greenville, North Carolina, United States of America
PLoS ONE 5:e11386. 2010..Such results can help to direct future genetic and biochemical investigations that tie together the complex impacts of the CTD on global cellular metabolism...