David S Chi

Summary

Affiliation: East Tennessee State University
Country: USA

Publications

  1. ncbi request reprint GM-CSF induction in human lung fibroblasts by IL-1beta, TNF-alpha, and macrophage contact
    S Matthew Fitzgerald
    Department of Internal Medicine, Division of Allergy and Immunology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37614, USA
    J Interferon Cytokine Res 23:57-65. 2003
  2. ncbi request reprint Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact
    S Matthew Fitzgerald
    Department of Internal Medicine, East Tennessee State University, Johnson City, TN 37614, USA
    Am J Respir Cell Mol Biol 30:585-93. 2004
  3. pmc Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway
    David S Chi
    Department of Internal Medicine, James H, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, USA
    Clin Mol Allergy 10:3. 2012
  4. pmc Incense smoke: clinical, structural and molecular effects on airway disease
    Ta Chang Lin
    Department of Environmental Engineering, National Cheng Kung University, Tainan, Taiwan
    Clin Mol Allergy 6:3. 2008
  5. pmc MAPK-dependent regulation of IL-1- and beta-adrenoreceptor-induced inflammatory cytokine production from mast cells: implications for the stress response
    David S Chi
    Department of Internal Medicine, James H, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, USA
    BMC Immunol 5:22. 2004
  6. pmc Baicalein inhibits IL-1beta- and TNF-alpha-induced inflammatory cytokine production from human mast cells via regulation of the NF-kappaB pathway
    Chia Jung Hsieh
    Departments of Internal Medicine, James H, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, USA
    Clin Mol Allergy 5:5. 2007
  7. ncbi request reprint Regulation of nitric oxide production from macrophages by lipopolysaccharide and catecholamines
    David S Chi
    Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, P O Box 70622, Johnson City, TN 37614 1709, USA
    Nitric Oxide 8:127-32. 2003
  8. ncbi request reprint Molecular regulation of interleukin-13 and monocyte chemoattractant protein-1 expression in human mast cells by interleukin-1beta
    Steven A Lee
    Department of Internal Medicine, East Tennessee State University, Johnson City, Tennessee 37614 1709, USA
    Am J Respir Cell Mol Biol 31:283-91. 2004
  9. ncbi request reprint Inhibition of GM-CSF production in fibroblast-monocyte coculture by prednisone and effects of rhGM-CSF on human lung fibroblasts
    S Matthew Fitzgerald
    Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, P O Box 70622 Johnson City, TN 37604, USA
    Front Biosci 9:342-8. 2004
  10. ncbi request reprint The role of human mast cell-derived cytokines in eosinophil biology
    Bita Shakoory
    Department of Internal Medicine, Division of Allergy and Immunology, East Tennessee State University, Johnson City, TN 37614, USA
    J Interferon Cytokine Res 24:271-81. 2004

Collaborators

  • Guha Krishnaswamy
  • S Matthew Fitzgerald
  • Chuanfu Li
  • Shau Ku Huang
  • David Johnson
  • Jie Wang
  • Elaine S Walker
  • Min Qui
  • Jonathan Moorman
  • Casey Watkins
  • Hana Saleh
  • Steven A Lee
  • Warit Jithpratuck
  • George Youngberg
  • Christopher Miller
  • Mariah B Pate
  • Mariah Pate
  • Ta Chang Lin
  • Chia Jung Hsieh
  • Jim Kelley
  • Raja S Vadlamudi
  • E Kasasbeh
  • Kai Liu
  • Billy Copeland
  • Denise M Milhorn
  • Walid Younis
  • Nader Eldika
  • Jim L Arter
  • Bita Shakoory
  • Nader Elgharib
  • Emma Peiris
  • Niva Misran
  • Eunkyung Song
  • Michelle L Altrich
  • Thomas Barklow
  • Gayatri Bala Jaishankar
  • Yasmin Elshenawy
  • Sara Wilgenbusch
  • John Kelly Smith
  • Vijay Damarla
  • Mini Michaels
  • Smita Negi
  • Tuanzhu Ha
  • Kenton Hall
  • Gregory Hemontolor
  • H Kenton Hall
  • Omar Aljitawi
  • Lakchminarayan Yerra
  • Bhuvana Guha
  • Girish M
  • Salim Wehbe

Detail Information

Publications29

  1. ncbi request reprint GM-CSF induction in human lung fibroblasts by IL-1beta, TNF-alpha, and macrophage contact
    S Matthew Fitzgerald
    Department of Internal Medicine, Division of Allergy and Immunology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37614, USA
    J Interferon Cytokine Res 23:57-65. 2003
    ..U937 membranes, as well as IL-1beta and TNF-alpha, induced nuclear translocation of NF-kappaB. These data support a prominent role for macrophage-fibroblast interactions in airway inflammation and fibrosis...
  2. ncbi request reprint Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact
    S Matthew Fitzgerald
    Department of Internal Medicine, East Tennessee State University, Johnson City, TN 37614, USA
    Am J Respir Cell Mol Biol 30:585-93. 2004
    ..These novel studies reveal the importance of cell-cell interactions in the complex milieu of airway inflammation...
  3. pmc Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway
    David S Chi
    Department of Internal Medicine, James H, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, USA
    Clin Mol Allergy 10:3. 2012
    ..abstract:..
  4. pmc Incense smoke: clinical, structural and molecular effects on airway disease
    Ta Chang Lin
    Department of Environmental Engineering, National Cheng Kung University, Tainan, Taiwan
    Clin Mol Allergy 6:3. 2008
    ..In order to prevent airway disease and other health problem, it is advisable that people should reduce the exposure time when they worship at the temple with heavy incense smokes, and ventilate their house when they burn incense at home...
  5. pmc MAPK-dependent regulation of IL-1- and beta-adrenoreceptor-induced inflammatory cytokine production from mast cells: implications for the stress response
    David S Chi
    Department of Internal Medicine, James H, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, USA
    BMC Immunol 5:22. 2004
    ..The aim of this study was to determine the effects of epinephrine on IL-1-induced proatherogenic cytokine production from mast cells...
  6. pmc Baicalein inhibits IL-1beta- and TNF-alpha-induced inflammatory cytokine production from human mast cells via regulation of the NF-kappaB pathway
    Chia Jung Hsieh
    Departments of Internal Medicine, James H, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, USA
    Clin Mol Allergy 5:5. 2007
    ..We examined its effects and mechanisms on the expression of inflammatory cytokines in an IL-1beta- and TNF-alpha-activated human mast cell line, HMC-1...
  7. ncbi request reprint Regulation of nitric oxide production from macrophages by lipopolysaccharide and catecholamines
    David S Chi
    Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, P O Box 70622, Johnson City, TN 37614 1709, USA
    Nitric Oxide 8:127-32. 2003
    ....
  8. ncbi request reprint Molecular regulation of interleukin-13 and monocyte chemoattractant protein-1 expression in human mast cells by interleukin-1beta
    Steven A Lee
    Department of Internal Medicine, East Tennessee State University, Johnson City, Tennessee 37614 1709, USA
    Am J Respir Cell Mol Biol 31:283-91. 2004
    ....
  9. ncbi request reprint Inhibition of GM-CSF production in fibroblast-monocyte coculture by prednisone and effects of rhGM-CSF on human lung fibroblasts
    S Matthew Fitzgerald
    Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, P O Box 70622 Johnson City, TN 37604, USA
    Front Biosci 9:342-8. 2004
    ..These data indicate mechanism of action and treatment for cell-cell contact mediated inflammation of infiltrating monocytes with fibroblasts as seen in asthma and other diseases like graft versus host disease...
  10. ncbi request reprint The role of human mast cell-derived cytokines in eosinophil biology
    Bita Shakoory
    Department of Internal Medicine, Division of Allergy and Immunology, East Tennessee State University, Johnson City, TN 37614, USA
    J Interferon Cytokine Res 24:271-81. 2004
    ..This two-way interaction between eosinophils and mast cells can pave the way for chronic inflammatory responses in a variety of human diseases. This review summarizes this pivotal interaction between human mast cells and eosinophils...
  11. ncbi request reprint Mast cell histamine and cytokine assays
    David S Chi
    Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA
    Methods Mol Biol 315:203-15. 2006
    ..Cytokine gene expression was evaluated by reverse transcriptase polymerase chain reaction and cytokine production was assayed in culture supernatants using an enzyme-linked immunosorbent assay kit...
  12. pmc Induction of p38- and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein
    Jonathan P Moorman
    Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA
    Respir Res 6:105. 2005
    ....
  13. ncbi request reprint Mast cell activation by lipoproteins
    Jim Kelley
    Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA
    Methods Mol Biol 315:341-8. 2006
    ..IL-8 mRNA levels were measured by reverse-transcription polymerase chain reaction and protein levels by enzyme-linked immunoassay...
  14. ncbi request reprint Regulation of eosinophil-active cytokine production from human cord blood-derived mast cells
    Guha Krishnaswamy
    Department of Medicine, East Tennessee State University, Johnson City, TN 37614 0622, USA
    J Interferon Cytokine Res 22:379-88. 2002
    ..A macrophage-mast cell-eosinophil axis may exist in vivo that may be susceptible to pharmacologic manipulation...
  15. ncbi request reprint Obstructive sleep apnea, inflammation, and cardiopulmonary disease
    Jim L Arter
    Division of Allergy and Immunology, Department of Medicine, James H Quillen College of Medicine and East Tennessee State University, Johnson City, Tennessee 37614 1709, USA
    Front Biosci 9:2892-900. 2004
    ..The purpose of this manuscript is to review the inflammatory responses that occur in patients with obstructive sleep apnea and relate them to the occurrence of cardiopulmonary disease...
  16. ncbi request reprint The human mast cell: an overview
    Guha Krishnaswamy
    Division of Allergy and Immunology, Department of Internal Medicine, James H Quillen VAMC and the Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA
    Methods Mol Biol 315:13-34. 2006
    ..This chapter summarizes the many well-known and novel functional aspects of human mast cell biology and emphasizes their unique role in the inflammatory response...
  17. ncbi request reprint Inflammatory aspects of sleep apnea and their cardiovascular consequences
    E Kasasbeh
    Division of Allergy and Immunology, Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA
    South Med J 99:58-67; quiz 68-9, 81. 2006
    ..Leukocyte adhesion and accumulation on endothelial cells are common in both OSA and atherosclerosis. Clinicians should be aware that OSA may be a risk factor for the development of cardiovascular disease...
  18. ncbi request reprint Endothelial cell biology: role in the inflammatory response
    Mariah Pate
    Division of Allergy and Immunology, Department of Internal Medicine, Quillen College of Medicine and James H Quillen VA Medical Center, Johnson City, Tennessee, USA
    Adv Clin Chem 52:109-30. 2010
    ....
  19. ncbi request reprint Atherosclerosis as an inflammatory disease: implications for therapy
    Nader Eldika
    Department of Internal Medicine, East Tennessee State University, Box70622, Johnson City, TN 37614 1709, USA
    Front Biosci 9:2764-77. 2004
    ..Therapeutic targets could include cytokine pathways, growth factors, transcription factors, defective genes and other intracellular metabolic pathways...
  20. ncbi request reprint Concomitant gene mutations of MBL and CYBB in chronic granulomatous disease: implications for host defense
    Casey Watkins
    Department of Internal Medicine, Quillen College of Medicine, James H Quillen VA Medical Center, Johnson City, P O Box 70622, TN 37614 0622, USA
    Inflamm Allergy Drug Targets 11:222-6. 2012
    ..Further studies looking at the frequency and implications of MBL deficiency in CGD are needed...
  21. pmc The clinical implications of adult-onset henoch-schonelin purpura
    Warit Jithpratuck
    Departments of Internal Medicine, Quillen College of Medicine, East Tennessee State University, TN, USA
    Clin Mol Allergy 9:9. 2011
    ..Though it primarily affects children (over 90% of cases), the occurrence in adults has been rarely reported. Management often involves the use of immunomodulatory or immune-suppressive regimens...
  22. pmc Molecular defects in the mannose binding lectin pathway in dermatological disease: Case report and literature review
    Christopher Miller
    Internal Medicine, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA
    Clin Mol Allergy 8:6. 2010
    ..The mechanisms may relate to the role of this pathway in innate immunity, removal of apoptotic cells and in immune complexes. Further study of MBL pathway defects in dermatological disease is required...
  23. ncbi request reprint C-reactive protein as a novel biomarker. Reactant can flag atherosclerosis and help predict cardiac events
    Nader Elgharib
    Division of Allergy and Immunology, Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, PO Box 70622, Johnson City, TN 37614 1709, USA
    Postgrad Med 114:39-44; quiz 16. 2003
    ..In this article, the authors review the role of CRP in the diagnosis, monitoring, and treatment of various forms of ischemic and inflammatory cardiovascular disease...
  24. ncbi request reprint Bacterial activation of mast cells
    David S Chi
    Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA
    Methods Mol Biol 315:383-92. 2006
    ..Direct bacterial contact with mast cells appears to be essential for this activation because neither cell-free bacterial supernatants nor bacterial lipopolysaccharide induce cytokine secretion...
  25. pmc Intestinal strongyloidiasis and hyperinfection syndrome
    Raja S Vadlamudi
    Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, VA Building 1, Johnson City, Tennessee, USA
    Clin Mol Allergy 4:8. 2006
    ....
  26. pmc Regulation and dysregulation of immunoglobulin E: a molecular and clinical perspective
    Mariah B Pate
    Division of Allergy and Immunology, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA
    Clin Mol Allergy 8:3. 2010
    ..The object of this review is to summarize the historical and molecular aspects of IgE synthesis and the disorders associated with dysregulation of IgE production...
  27. ncbi request reprint A patient with facial and neck swelling, dyspnea, and dysphagia
    Billy Copeland
    Department of Internal Medicine, East Tennessee State University, Johnson City, Tennessee 37614 1709, USA
    Ann Allergy Asthma Immunol 95:510-7. 2005
  28. ncbi request reprint Comparison of cytotoxin genotypes of Helicobacter pylori in stomach and saliva
    Jie Wang
    Department of Intemal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City 37614, USA
    Dig Dis Sci 47:1850-6. 2002
    ..DNA sequencing from three patients showed 78.0%, 64.0%, and 66.9% homology of H. pylori from both sources, respectively. The data suggest that more than one H. pylori strain may exist in the stomach and saliva in the same patient...
  29. ncbi request reprint HIV-1 Tat protein-induced VCAM-1 expression in human pulmonary artery endothelial cells and its signaling
    Kai Liu
    Department of Medicine, Tulane Univ School of Medicine, New Orleans, LA 70112 2699, USA
    Am J Physiol Lung Cell Mol Physiol 289:L252-60. 2005
    ....