Sassan Asgari

Summary

Affiliation: East Carolina University
Country: USA

Publications

  1. ncbi request reprint Venom proteins from polydnavirus-producing endoparasitoids: their role in host-parasite interactions
    Sassan Asgari
    School of Integrative Biology, University of Queensland, St Lucia, Queensland, Australia
    Arch Insect Biochem Physiol 61:146-56. 2006
  2. pmc Wolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegypti
    Mazhar Hussain
    School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia
    Proc Natl Acad Sci U S A 108:9250-5. 2011
  3. pmc Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti
    Guangmei Zhang
    Australian Infectious Disease Research Centre, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia
    Proc Natl Acad Sci U S A 110:10276-81. 2013
  4. doi request reprint Suppression of scavenger receptors transcription by parasitoid factors
    Kayvan Etebari
    School of Biological Sciences, The University of Queensland, St Lucia, Australia
    Dev Comp Immunol 38:517-24. 2012
  5. doi request reprint Inhibition of apoptosis by Heliothis virescens ascovirus (HvAV-3e): characterization of orf28 with structural similarity to inhibitor of apoptosis proteins
    Mazhar Hussain
    School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
    Apoptosis 13:1417-26. 2008
  6. doi request reprint Cloning and characterization of a Dim1-like mitosis gene of Spodoptera frugiperda cells (Sf9) induced by Autographa californica multiple nucleopolyhedrovirus
    Mohammad Mehrabadi
    School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
    J Invertebr Pathol 113:152-9. 2013
  7. doi request reprint An insect trypsin-like serine protease as a target of microRNA: utilization of microRNA mimics and inhibitors by oral feeding
    Balachandran Jayachandran
    School of Biological Sciences, The University of Queensland, Brisbane, St Lucia, QLD 4072, Australia
    Insect Biochem Mol Biol 43:398-406. 2013
  8. pmc Wolbachia-induced aae-miR-12 miRNA negatively regulates the expression of MCT1 and MCM6 genes in Wolbachia-infected mosquito cell line
    Solomon Osei-Amo
    School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia
    PLoS ONE 7:e50049. 2012
  9. doi request reprint Blood meal induced microRNA regulates development and immune associated genes in the Dengue mosquito vector, Aedes aegypti
    Mazhar Hussain
    Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia
    Insect Biochem Mol Biol 43:146-52. 2013
  10. doi request reprint Identification of microRNAs from Plutella xylostella larvae associated with parasitization by Diadegma semiclausum
    Kayvan Etebari
    School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
    Insect Biochem Mol Biol 43:309-18. 2013

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Venom proteins from polydnavirus-producing endoparasitoids: their role in host-parasite interactions
    Sassan Asgari
    School of Integrative Biology, University of Queensland, St Lucia, Queensland, Australia
    Arch Insect Biochem Physiol 61:146-56. 2006
    ..rubecula venom proteins in host-parasitoid interactions...
  2. pmc Wolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegypti
    Mazhar Hussain
    School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia
    Proc Natl Acad Sci U S A 108:9250-5. 2011
    ..This report shows how Wolbachia alters the host miRNA profile and provides insight into the mechanisms of host manipulation used by this widespread endosymbiont...
  3. pmc Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti
    Guangmei Zhang
    Australian Infectious Disease Research Centre, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia
    Proc Natl Acad Sci U S A 110:10276-81. 2013
    ..In addition, our findings provide an explanation for hypomethylation of the genome in Wolbachia-infected Ae. aegypti...
  4. doi request reprint Suppression of scavenger receptors transcription by parasitoid factors
    Kayvan Etebari
    School of Biological Sciences, The University of Queensland, St Lucia, Australia
    Dev Comp Immunol 38:517-24. 2012
    ..In conclusion, it appears that the two members of the SR family play important roles in innate immune responses in P. xylostella and that each member of this group may play different roles in the host-parasitoid interaction...
  5. doi request reprint Inhibition of apoptosis by Heliothis virescens ascovirus (HvAV-3e): characterization of orf28 with structural similarity to inhibitor of apoptosis proteins
    Mazhar Hussain
    School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
    Apoptosis 13:1417-26. 2008
    ..Nevertheless, RNA interference studies revealed that the gene is probably essential for virus pathology and replication...
  6. doi request reprint Cloning and characterization of a Dim1-like mitosis gene of Spodoptera frugiperda cells (Sf9) induced by Autographa californica multiple nucleopolyhedrovirus
    Mohammad Mehrabadi
    School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
    J Invertebr Pathol 113:152-9. 2013
    ..Overall, the results showed that SfDim1 protein is involved in cell proliferation as well as cell-virus interaction...
  7. doi request reprint An insect trypsin-like serine protease as a target of microRNA: utilization of microRNA mimics and inhibitors by oral feeding
    Balachandran Jayachandran
    School of Biological Sciences, The University of Queensland, Brisbane, St Lucia, QLD 4072, Australia
    Insect Biochem Mol Biol 43:398-406. 2013
    ..This is the first study which shows the potential of utilization of miRNA mimics and inhibitors in pest control by targeting specific insect genes...
  8. pmc Wolbachia-induced aae-miR-12 miRNA negatively regulates the expression of MCT1 and MCM6 genes in Wolbachia-infected mosquito cell line
    Solomon Osei-Amo
    School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia
    PLoS ONE 7:e50049. 2012
    ..MicroRNAs (miRNAs) have been determined to have a wide range of roles in regulating gene expression in eukaryotes. A recent study showed that several A. aegypti mosquito miRNAs are differentially expressed when infected with Wolbachia...
  9. doi request reprint Blood meal induced microRNA regulates development and immune associated genes in the Dengue mosquito vector, Aedes aegypti
    Mazhar Hussain
    Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia
    Insect Biochem Mol Biol 43:146-52. 2013
    ..In addition, we demonstrate that aae-miR-375 enhances Dengue virus serotype 2 (DENV-2) infection in an Ae. aegypti cell line...
  10. doi request reprint Identification of microRNAs from Plutella xylostella larvae associated with parasitization by Diadegma semiclausum
    Kayvan Etebari
    School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
    Insect Biochem Mol Biol 43:309-18. 2013
    ..In conclusion, expression profiling of miRNAs provided insights into their possible involvement in insect immune response to parasitism and offer an important resource for further studies...
  11. ncbi request reprint Regulation of Helicoverpa armigera ecdysone receptor by miR-14 and its potential link to baculovirus infection
    Balachandran Jayachandran
    School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
    J Invertebr Pathol 114:151-7. 2013
    ..These results suggest that, by down-regulating miR-14, HaSNPV may reduce the Ha-EcR transcript levels providing another classic example of virus-mediated manipulation of host physiology. ..
  12. doi request reprint MicroRNAome of Spodoptera frugiperda cells (Sf9) and its alteration following baculovirus infection
    Mohammad Mehrabadi
    School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia
    J Gen Virol 94:1385-97. 2013
    ..Seed shifting and arm switching happened during evolution of miRNAs in different insects and caused miRNA diversification, which led to changes in the target repository of miRNAs...
  13. doi request reprint A lipase-like gene from Heliothis virescens ascovirus (HvAV-3e) is essential for virus replication and cell cleavage
    Matthew Smede
    School of Biological Sciences, University of Queensland, St Lucia, QLD, Australia
    Virus Genes 39:409-17. 2009
    ..However, under enzymatic assays tested, we did not detect any lipase or esterase activity from ORF19...
  14. pmc An Ascovirus-encoded RNase III autoregulates its expression and suppresses RNA interference-mediated gene silencing
    Mazhar Hussain
    School of Biological Sciences, The University of Queensland, St Lucia, Queensland 4072, Australia
    J Virol 84:3624-30. 2010
    ..To our knowledge, this is the first insect virus-encoded RNase III described and shown to suppress host cell RNAi defense mechanism...
  15. doi request reprint The role of actin filaments in ascovirus replication and pathology
    Mazhar Hussain
    School of Biological Sciences, University of Queensland, St Lucia, QLD, 4072, Australia
    Arch Virol 154:1737-43. 2009
    ..These observations suggested that actin may not be required for virus entry and replication but essential for virus pathology, mainly vesicle formation...
  16. doi request reprint Effects of Heliothis virescens ascovirus (HvAV-3e) on a novel host, Crocidolomia pavonana (Lepidoptera: Crambidae)
    Matthew Smede
    School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
    J Invertebr Pathol 99:281-5. 2008
    ....
  17. ncbi request reprint A caspase-like gene from Heliothis virescens ascovirus (HvAV-3e) is not involved in apoptosis but is essential for virus replication
    Sassan Asgari
    School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
    Virus Res 128:99-105. 2007
    ..HvAV codes for a caspase-like protein but no apoptosis was observed when the gene was expressed in vitro. RNAi studies indicated that the gene is essential for virus replication...
  18. pmc RNA interference as a cellular defense mechanism against the DNA virus baculovirus
    Balachandran Jayachandran
    School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia
    J Virol 86:13729-34. 2012
    ..This may, however, be to the advantage of the virus by preventing overreplication of the virus, which may otherwise lead to the premature death of the host cells...
  19. pmc Effect of Wolbachia on replication of West Nile virus in a mosquito cell line and adult mosquitoes
    Mazhar Hussain
    Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
    J Virol 87:851-8. 2013
    ....
  20. pmc An insect virus-encoded microRNA regulates viral replication
    Mazhar Hussain
    School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
    J Virol 82:9164-70. 2008
    ..These findings are congruent with recent reports that miR-BART-2 regulates Epstein-Barr virus DNA polymerase expression and suggest that virus-encoded miRNA regulation of virus replication may be a general phenomenon...
  21. pmc Functional analysis of a cellular microRNA in insect host-ascovirus interaction
    Mazhar Hussain
    The University of Queensland, St Lucia, Queensland 4072, Australia
    J Virol 84:612-20. 2010
    ..To our knowledge, this is the first cellular miRNA reported to interact with an insect virus...
  22. pmc Wolbachia infection modifies the profile, shuttling and structure of microRNAs in a mosquito cell line
    Jaime G Mayoral
    Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia
    PLoS ONE 9:e96107. 2014
    ....
  23. doi request reprint MicroRNA functions in insects
    Sassan Asgari
    School of Biological Sciences, The University of Queensland, Brisbane, St Lucia, QLD 4072, Australia
    Insect Biochem Mol Biol 43:388-97. 2013
    ..Here, I review what is currently known about miRNA functions in insects to provide an insight into their diverse roles in insect biology...
  24. ncbi request reprint Sequence and organization of the Heliothis virescens ascovirus genome
    Sassan Asgari
    School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
    J Gen Virol 88:1120-32. 2007
    ..Gene-parity plots and overall similarity of ORFs indicate that HvAV-3e is related more closely to SfAV-1a than to TnAV-2c...
  25. ncbi request reprint Isolation of an imaginal disc growth factor homologue from Pieris rapae and its expression following parasitization by Cotesia rubecula
    Sassan Asgari
    Department of Zoology and Entomology, School of Life Sciences, University of Queensland, St Lucia, QLD 4072, Australia
    J Insect Physiol 50:687-94. 2004
    ..rapae IDGF is not affected by parasitization and polydnavirus infection. However, the amount of highly expressed genes, such as storage proteins, arylphorin and lipophorin, are significantly reduced following parasitization...
  26. pmc Accuracy of microRNA discovery pipelines in non-model organisms using closely related species genomes
    Kayvan Etebari
    School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia
    PLoS ONE 9:e84747. 2014
    ..Although using closely related species genome incurred some losses in the number of miRNAs, the most abundant miRNAs along with their differential expression profile would be acceptable based on the sensitivity level of each project. ..
  27. doi request reprint Infection with the wMel and wMelPop strains of Wolbachia leads to higher levels of melanization in the hemolymph of Drosophila melanogaster, Drosophila simulans and Aedes aegypti
    Pune Thomas
    School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
    Dev Comp Immunol 35:360-5. 2011
    ..HPLC analysis of hemolymph from mosquitoes showed that this difference was not due to dopamine levels in the host as they were no different in wMelPop-infected and control mosquitoes before or after blood feeding...
  28. ncbi request reprint A novel venom peptide from an endoparasitoid wasp is required for expression of polydnavirus genes in host hemocytes
    Guangmei Zhang
    Insect Molecular Biology Laboratory, Department of Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond SA 5064, Australia
    J Biol Chem 279:41580-5. 2004
    ..The peptide consists of 14 amino acids with a molecular mass of 1598 Da. In the absence of Vn1.5 or total venom proteins, CrBV genes are not expressed in host cells and did not cause inactivation of host hemocytes...
  29. ncbi request reprint Parasitization of Manduca sexta larvae by the parasitoid wasp Cotesia congregata induces an impaired host immune response
    Kevin E Amaya
    Departments of Entomology and Cell Biology and Neuroscience, University of California Riverside, 5419 Boyce Hall, Riverside, CA 92521, USA
    J Insect Physiol 51:505-12. 2005
    ..A CrV1-homolog gene product was localized in host hemocytes using polyclonal CrV1 antibodies, suggesting that CrV1-like gene products of C. congregata's bracovirus are responsible for the impaired immune response of the host...
  30. ncbi request reprint Isolation and characterization of a novel venom protein from an endoparasitoid, Cotesia rubecula (Hym: Braconidae)
    Sassan Asgari
    Department of Applied and Molecular Ecology, The University of Adelaide, Glen Osmond, South Australia
    Arch Insect Biochem Physiol 53:92-100. 2003
    ..The coding region for Vn4.6 is located upstream in the opposite direction of a gene coding for a C. rubecula PDV-protein (Crp32)...
  31. ncbi request reprint Characterization of a novel protein with homology to C-type lectins expressed by the Cotesia rubecula bracovirus in larvae of the lepidopteran host, Pieris rapae
    Richard Glatz
    Department of Applied and Molecular Ecology, Waite Campus, The University of Adelaide, Glen Osmond, South Australia 5064, Australia
    J Biol Chem 278:19743-50. 2003
    ..The high similarity of CrV3 with invertebrate lectins, as opposed to those from viruses, may indicate that some bracovirus functions were acquired from their hosts...
  32. ncbi request reprint Polydnavirus particle proteins with similarities to molecular chaperones, heat-shock protein 70 and calreticulin
    Sassan Asgari
    Department of Applied and Molecular Ecology, Waite Campus, The University of Adelaide, Glen Osmond, South Australia 5064, Australia
    J Gen Virol 84:1165-71. 2003
    ..Here we report on two genes encoding Cotesia rubecula particle proteins with similarities to molecular chaperones, calreticulin and heat-shock protein 70...
  33. ncbi request reprint Virus or not? Phylogenetics of polydnaviruses and their wasp carriers
    James B Whitfield
    Department of Entomology, University of Illinois, Urbana, IL 61801, USA
    J Insect Physiol 49:397-405. 2003
    ..Ongoing sequencing studies of entire PDV genomes from diverse wasp species are likely to greatly contribute to our understanding of PDV evolution...
  34. ncbi request reprint A serine proteinase homolog venom protein from an endoparasitoid wasp inhibits melanization of the host hemolymph
    Sassan Asgari
    Insect Molecular Biology Lab, Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond, SA 5064, Australia
    Insect Biochem Mol Biol 33:1017-24. 2003
    ..The data presented here indicate that the protein interferes with the proteolytic cascade, which under normal circumstances leads to the activation of proPO and melanin formation...
  35. ncbi request reprint Negative regulation of prophenoloxidase (proPO) activation by a clip-domain serine proteinase homolog (SPH) from endoparasitoid venom
    Guangmei Zhang
    Insect Molecular Biology Laboratory, Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond, SA 5064, Australia
    Insect Biochem Mol Biol 34:477-83. 2004
    ..sexta proPO, PAP-1, and SPHs were impaired by this venom protein. A similar strategy might be employed by C. rubecula to negatively impact the proPO activation reaction in its natural host...
  36. ncbi request reprint Evolutionary origin of Venturia canescens virus-like particles
    Annette Reineke
    Max Planck Institute for Chemical Ecology, Department of Entomology, Jena, Germany
    Arch Insect Biochem Physiol 61:123-33. 2006
    ..canescens VLP proteins are more related to cellular proteins than to viruses...
  37. ncbi request reprint Isolation and characterization of a Cotesia rubecula bracovirus gene expressed in the lepidopteran Pieris rapae
    Richard Glatz
    Insect Molecular Biology, University of Adelaide, Waite Campus, Glen Osmond, SA 5064, Australia
    J Gen Virol 85:2873-82. 2004
    ..CrV2 has a coiled-coil region predicted at its C-terminus, which may be involved in the formation of putative CrV2 trimers that are detected in haemolymph of parasitized host larvae...
  38. ncbi request reprint Evolution of polydnaviruses as insect immune suppressors
    Richard V Glatz
    Insect Molecular Biology Laboratory, University of Adelaide, Waite Campus, Glen Osmond, SA 5064, Australia
    Trends Microbiol 12:545-54. 2004
    ..These phenomena provide further insights into the immune-suppressive activity of PDVs and raise interesting questions about PDV evolution, a topic that has puzzled researchers ever since the discovery of PDVs...
  39. ncbi request reprint Presence of a novel small RNA-containing virus in a laboratory culture of the endoparasitic wasp Venturia canescens (Hymenoptera: Ichneumonidae)
    Annette Reineke
    University of Hohenheim, Institute of Phytomedicine, D 70593 Stuttgart, Germany
    J Insect Physiol 51:127-35. 2005
    ..kuehniella larvae where they enter hemocytes. Alignment of the RNA-dependent RNA polymerase gene of VcSRV indicates that the virus most likely belongs to the recently described genus Iflavirus...
  40. ncbi request reprint Are insect immune suppressors driving cellular uptake reactions?
    Otto Schmidt
    Insect Molecular Biology, School of Agriculture and Wine, University of Adelaide, Glen Osmond, Australia
    Arch Insect Biochem Physiol 60:153-8. 2005
    ....
  41. ncbi request reprint A calreticulin-like protein from endoparasitoid venom fluid is involved in host hemocyte inactivation
    Guangmei Zhang
    Insect Molecular Biology Laboratory, Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond, SA 5064, Australia
    Dev Comp Immunol 30:756-64. 2006
    ..It is possible that the protein might function as an antagonist competing for binding sites with the host hemocyte calreticulin, which mediates early-encapsulation reactions...
  42. ncbi request reprint A coiled-coil region of an insect immune suppressor protein is involved in binding and uptake by hemocytes
    Sassan Asgari
    Department of Applied and Molecular Ecology, Waite Campus, Adelaide University, Glen Osmond, SA 5064, Australia
    Insect Biochem Mol Biol 32:497-504. 2002
    ..Here, we show that a coiled-coil domain containing a putative leucine zipper is required for CrV1 function, since removal of this domain abolishes binding and uptake of the CrV1 protein by hemocytes...