Research Topics
| Sassan AsgariSummaryAffiliation: East Carolina University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Venom proteins from polydnavirus-producing endoparasitoids: their role in host-parasite interactionsSassan Asgari
School of Integrative Biology, University of Queensland, St Lucia, Queensland, Australia
Arch Insect Biochem Physiol 61:146-56. 2006..rubecula venom proteins in host-parasitoid interactions...
Wolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegyptiMazhar Hussain
School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia
Proc Natl Acad Sci U S A 108:9250-5. 2011..This report shows how Wolbachia alters the host miRNA profile and provides insight into the mechanisms of host manipulation used by this widespread endosymbiont...
Inhibition of apoptosis by Heliothis virescens ascovirus (HvAV-3e): characterization of orf28 with structural similarity to inhibitor of apoptosis proteinsMazhar Hussain
School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
Apoptosis 13:1417-26. 2008..Nevertheless, RNA interference studies revealed that the gene is probably essential for virus pathology and replication...- An Ascovirus-encoded RNase III autoregulates its expression and suppresses RNA interference-mediated gene silencingMazhar Hussain
School of Biological Sciences, The University of Queensland, St Lucia, Queensland 4072, Australia
J Virol 84:3624-30. 2010..To our knowledge, this is the first insect virus-encoded RNase III described and shown to suppress host cell RNAi defense mechanism... - A lipase-like gene from Heliothis virescens ascovirus (HvAV-3e) is essential for virus replication and cell cleavageMatthew Smede
School of Biological Sciences, University of Queensland, St Lucia, QLD, Australia
Virus Genes 39:409-17. 2009..However, under enzymatic assays tested, we did not detect any lipase or esterase activity from ORF19... - A caspase-like gene from Heliothis virescens ascovirus (HvAV-3e) is not involved in apoptosis but is essential for virus replicationSassan Asgari
School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
Virus Res 128:99-105. 2007..HvAV codes for a caspase-like protein but no apoptosis was observed when the gene was expressed in vitro. RNAi studies indicated that the gene is essential for virus replication... - Effects of Heliothis virescens ascovirus (HvAV-3e) on a novel host, Crocidolomia pavonana (Lepidoptera: Crambidae)Matthew Smede
School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
J Invertebr Pathol 99:281-5. 2008.... - The role of actin filaments in ascovirus replication and pathologyMazhar Hussain
School of Biological Sciences, University of Queensland, St Lucia, QLD, 4072, Australia
Arch Virol 154:1737-43. 2009..These observations suggested that actin may not be required for virus entry and replication but essential for virus pathology, mainly vesicle formation... - Effect of Wolbachia on replication of West Nile virus in a mosquito cell line and adult mosquitoesMazhar Hussain
Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
J Virol 87:851-8. 2013.... - RNA interference as a cellular defense mechanism against the DNA virus baculovirusBalachandran Jayachandran
School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia
J Virol 86:13729-34. 2012..This may, however, be to the advantage of the virus by preventing overreplication of the virus, which may otherwise lead to the premature death of the host cells... - An insect virus-encoded microRNA regulates viral replicationMazhar Hussain
School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
J Virol 82:9164-70. 2008..These findings are congruent with recent reports that miR-BART-2 regulates Epstein-Barr virus DNA polymerase expression and suggest that virus-encoded miRNA regulation of virus replication may be a general phenomenon... - Functional analysis of a cellular microRNA in insect host-ascovirus interactionMazhar Hussain
The University of Queensland, St Lucia, Queensland 4072, Australia
J Virol 84:612-20. 2010..To our knowledge, this is the first cellular miRNA reported to interact with an insect virus... - Identification of microRNAs from Plutella xylostella larvae associated with parasitization by Diadegma semiclausumKayvan Etebari
School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
Insect Biochem Mol Biol 43:309-18. 2013..In conclusion, expression profiling of miRNAs provided insights into their possible involvement in insect immune response to parasitism and offer an important resource for further studies... - An insect trypsin-like serine protease as a target of microRNA: utilization of microRNA mimics and inhibitors by oral feedingBalachandran Jayachandran
School of Biological Sciences, The University of Queensland, Brisbane, St Lucia, QLD 4072, Australia
Insect Biochem Mol Biol 43:398-406. 2013..This is the first study which shows the potential of utilization of miRNA mimics and inhibitors in pest control by targeting specific insect genes... - Blood meal induced microRNA regulates development and immune associated genes in the Dengue mosquito vector, Aedes aegyptiMazhar Hussain
Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia
Insect Biochem Mol Biol 43:146-52. 2013..In addition, we demonstrate that aae-miR-375 enhances Dengue virus serotype 2 (DENV-2) infection in an Ae. aegypti cell line... - Wolbachia-induced aae-miR-12 miRNA negatively regulates the expression of MCT1 and MCM6 genes in Wolbachia-infected mosquito cell lineSolomon Osei-Amo
School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia
PLoS ONE 7:e50049. 2012..MicroRNAs (miRNAs) have been determined to have a wide range of roles in regulating gene expression in eukaryotes. A recent study showed that several A. aegypti mosquito miRNAs are differentially expressed when infected with Wolbachia... - Sequence and organization of the Heliothis virescens ascovirus genomeSassan Asgari
School of Integrative Biology, University of Queensland, St Lucia, QLD 4072, Australia
J Gen Virol 88:1120-32. 2007..Gene-parity plots and overall similarity of ORFs indicate that HvAV-3e is related more closely to SfAV-1a than to TnAV-2c... - Isolation of an imaginal disc growth factor homologue from Pieris rapae and its expression following parasitization by Cotesia rubeculaSassan Asgari
Department of Zoology and Entomology, School of Life Sciences, University of Queensland, St Lucia, QLD 4072, Australia
J Insect Physiol 50:687-94. 2004..rapae IDGF is not affected by parasitization and polydnavirus infection. However, the amount of highly expressed genes, such as storage proteins, arylphorin and lipophorin, are significantly reduced following parasitization... - Suppression of scavenger receptors transcription by parasitoid factorsKayvan Etebari
School of Biological Sciences, The University of Queensland, St Lucia, Australia
Dev Comp Immunol 38:517-24. 2012..In conclusion, it appears that the two members of the SR family play important roles in innate immune responses in P. xylostella and that each member of this group may play different roles in the host-parasitoid interaction... - Infection with the wMel and wMelPop strains of Wolbachia leads to higher levels of melanization in the hemolymph of Drosophila melanogaster, Drosophila simulans and Aedes aegyptiPune Thomas
School of Biological Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
Dev Comp Immunol 35:360-5. 2011..HPLC analysis of hemolymph from mosquitoes showed that this difference was not due to dopamine levels in the host as they were no different in wMelPop-infected and control mosquitoes before or after blood feeding... - Parasitization of Manduca sexta larvae by the parasitoid wasp Cotesia congregata induces an impaired host immune responseKevin E Amaya
Departments of Entomology and Cell Biology and Neuroscience, University of California-Riverside, 5419 Boyce Hall, Riverside, CA 92521, USA
J Insect Physiol 51:505-12. 2005..A CrV1-homolog gene product was localized in host hemocytes using polyclonal CrV1 antibodies, suggesting that CrV1-like gene products of C. congregata's bracovirus are responsible for the impaired immune response of the host... - Isolation and characterization of a novel venom protein from an endoparasitoid, Cotesia rubecula (Hym: Braconidae)Sassan Asgari
Department of Applied and Molecular Ecology, The University of Adelaide, Glen Osmond, South Australia
Arch Insect Biochem Physiol 53:92-100. 2003..The coding region for Vn4.6 is located upstream in the opposite direction of a gene coding for a C. rubecula PDV-protein (Crp32)... - A novel venom peptide from an endoparasitoid wasp is required for expression of polydnavirus genes in host hemocytesGuangmei Zhang
Insect Molecular Biology Laboratory, Department of Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond SA 5064, Australia
J Biol Chem 279:41580-5. 2004..The peptide consists of 14 amino acids with a molecular mass of 1598 Da. In the absence of Vn1.5 or total venom proteins, CrBV genes are not expressed in host cells and did not cause inactivation of host hemocytes... - Polydnavirus particle proteins with similarities to molecular chaperones, heat-shock protein 70 and calreticulinSassan Asgari
Department of Applied and Molecular Ecology, Waite Campus, The University of Adelaide, Glen Osmond, South Australia 5064, Australia
J Gen Virol 84:1165-71. 2003..Here we report on two genes encoding Cotesia rubecula particle proteins with similarities to molecular chaperones, calreticulin and heat-shock protein 70... - A serine proteinase homolog venom protein from an endoparasitoid wasp inhibits melanization of the host hemolymphSassan Asgari
Insect Molecular Biology Lab, Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond, SA 5064, Australia
Insect Biochem Mol Biol 33:1017-24. 2003..The data presented here indicate that the protein interferes with the proteolytic cascade, which under normal circumstances leads to the activation of proPO and melanin formation... - Characterization of a novel protein with homology to C-type lectins expressed by the Cotesia rubecula bracovirus in larvae of the lepidopteran host, Pieris rapaeRichard Glatz
Department of Applied and Molecular Ecology, Waite Campus, The University of Adelaide, Glen Osmond, South Australia 5064, Australia
J Biol Chem 278:19743-50. 2003..The high similarity of CrV3 with invertebrate lectins, as opposed to those from viruses, may indicate that some bracovirus functions were acquired from their hosts... - Virus or not? Phylogenetics of polydnaviruses and their wasp carriersJames B Whitfield
Department of Entomology, University of Illinois, Urbana, IL 61801, USA
J Insect Physiol 49:397-405. 2003..Ongoing sequencing studies of entire PDV genomes from diverse wasp species are likely to greatly contribute to our understanding of PDV evolution... - Negative regulation of prophenoloxidase (proPO) activation by a clip-domain serine proteinase homolog (SPH) from endoparasitoid venomGuangmei Zhang
Insect Molecular Biology Laboratory, Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond, SA 5064, Australia
Insect Biochem Mol Biol 34:477-83. 2004..sexta proPO, PAP-1, and SPHs were impaired by this venom protein. A similar strategy might be employed by C. rubecula to negatively impact the proPO activation reaction in its natural host... - Evolutionary origin of Venturia canescens virus-like particlesAnnette Reineke
Max Planck Institute for Chemical Ecology, Department of Entomology, Jena, Germany
Arch Insect Biochem Physiol 61:123-33. 2006..canescens VLP proteins are more related to cellular proteins than to viruses... - Isolation and characterization of a Cotesia rubecula bracovirus gene expressed in the lepidopteran Pieris rapaeRichard Glatz
Insect Molecular Biology, University of Adelaide, Waite Campus, Glen Osmond, SA 5064, Australia
J Gen Virol 85:2873-82. 2004..CrV2 has a coiled-coil region predicted at its C-terminus, which may be involved in the formation of putative CrV2 trimers that are detected in haemolymph of parasitized host larvae... - Evolution of polydnaviruses as insect immune suppressorsRichard V Glatz
Insect Molecular Biology Laboratory, University of Adelaide, Waite Campus, Glen Osmond, SA 5064, Australia
Trends Microbiol 12:545-54. 2004..These phenomena provide further insights into the immune-suppressive activity of PDVs and raise interesting questions about PDV evolution, a topic that has puzzled researchers ever since the discovery of PDVs... - Presence of a novel small RNA-containing virus in a laboratory culture of the endoparasitic wasp Venturia canescens (Hymenoptera: Ichneumonidae)Annette Reineke
University of Hohenheim, Institute of Phytomedicine, D 70593 Stuttgart, Germany
J Insect Physiol 51:127-35. 2005..kuehniella larvae where they enter hemocytes. Alignment of the RNA-dependent RNA polymerase gene of VcSRV indicates that the virus most likely belongs to the recently described genus Iflavirus... - Are insect immune suppressors driving cellular uptake reactions?Otto Schmidt
Insect Molecular Biology, School of Agriculture and Wine, University of Adelaide, Glen Osmond, Australia
Arch Insect Biochem Physiol 60:153-8. 2005.... - A calreticulin-like protein from endoparasitoid venom fluid is involved in host hemocyte inactivationGuangmei Zhang
Insect Molecular Biology Laboratory, Plant and Pest Science, Waite Campus, University of Adelaide, Glen Osmond, SA 5064, Australia
Dev Comp Immunol 30:756-64. 2006..It is possible that the protein might function as an antagonist competing for binding sites with the host hemocyte calreticulin, which mediates early-encapsulation reactions... - A coiled-coil region of an insect immune suppressor protein is involved in binding and uptake by hemocytesSassan Asgari
Department of Applied and Molecular Ecology, Waite Campus, Adelaide University, Glen Osmond, SA 5064, Australia
Insect Biochem Mol Biol 32:497-504. 2002..Here, we show that a coiled-coil domain containing a putative leucine zipper is required for CrV1 function, since removal of this domain abolishes binding and uptake of the CrV1 protein by hemocytes...