Research Topics
| Donald L FineSummaryAffiliation: DynPort Vaccine Company LLC Country: USA Publications
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Detail Information
Publications
Venezuelan equine encephalitis virus vaccine candidate (V3526) safety, immunogenicity and efficacy in horsesDonald L Fine
DynPort Vaccine Company LLC DVC, A CSC Company, 64 Thomas Johnson Drive, Frederick, MD 21702, USA
Vaccine 25:1868-76. 2007..The second study supported that repeat dosing resulted in an increase in serum neutralizing antibody to TrD...
Neurovirulence evaluation of Venezuelan equine encephalitis (VEE) vaccine candidate V3526 in nonhuman primatesDonald L Fine
DynPort Vaccine Company LLC DVC, A CSC Company, 64 Thormas Johnson Drive, Frederick, MD 21702, USA
Vaccine 26:3497-506. 2008..V3526 was immunogenic and essentially nonneurovirulent when administered via the clinically relevant subcutaneous route...
A multisystem approach for development and evaluation of inactivated vaccines for Venezuelan equine encephalitis virus (VEEV)Donald L Fine
DynPort Vaccine Company LLC DVC, A CSC Company, 64 Thomas Johnson Drive, Frederick, MD 21702, USA
J Virol Methods 163:424-32. 2010..The combination of in vitro and in vivo assays provides a practical approach to optimize manufacturing process parameters for development of other inactivated viral vaccines...
Evaluation of formalin inactivated V3526 virus with adjuvant as a next generation vaccine candidate for Venezuelan equine encephalitis virusShannon S Martin
DynPort Vaccine Company LLC, A CSC Company, 64 Thomas Johnson Drive, Frederick, MD 21702, USA
Vaccine 28:3143-51. 2010..These data support further evaluation of fV3526 formulations as a next generation VEEV vaccine...
Telemetric analysis to detect febrile responses in mice following vaccination with a live-attenuated virus vaccineShannon S Martin
DynPort Vaccine Company LLC DVC, A CSC Company, Frederick, MD 21702, USA
Vaccine 27:6814-23. 2009..From these studies, we conclude, outbred mouse strains implanted with telemeters are a sensitive model for predicting responses in humans following vaccination...
Comparison of the immunological responses and efficacy of gamma-irradiated V3526 vaccine formulations against subcutaneous and aerosol challenge with Venezuelan equine encephalitis virus subtype IABShannon S Martin
DynPort Vaccine Company LLC DVC, A CSC Company, Frederick, MD 21702, USA
Vaccine 28:1031-40. 2010..IM administration of gV3526 formulated with either CpG or CpG plus Alhydrogel further augmented the immune response in mice and resulted in 100% protection against aerosol challenge...
