R W King
Affiliation: DuPont Pharmaceuticals Company
- Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)beta-L-2',3'-dideoxy-3'-thiacytidineR W King
Avid Therapeutics, Inc, Philadelphia, Pennsylvania 19104, USA
Antimicrob Agents Chemother 42:3179-86. 1998..Therefore, we concluded that the antiviral activity of AT-61 is specific for HBV replication and most likely occurs at one of the steps between the synthesis of viral RNA and the packaging of pregenomic RNA into immature core particles...
- Phenylpropenamide derivatives as inhibitors of hepatitis B virus replicationR B Perni
Avid Therapeutics, Inc, Philadelphia, PA 19104, USA
Bioorg Med Chem Lett 10:2687-90. 2000..A series of substituted analogues of phenylpropenamide 6 has been prepared and evaluated in the HepAD38 cellular assay. Structure-activity relationships of this series are discussed...