Affiliation: DuPont Haskell Laboratory for Health and Environmental Sciences
Cahoon E, Ripp K, Hall S, Kinney A. Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid. J Biol Chem. 2001;276:2637-43 pubmed
..Regiospecificity for Delta(9)-double bonds is unprecedented among FAD2-related enzymes and further expands the functional diversity found in this family of enzymes. ..
Cahoon E, Ripp K, Hall S, McGonigle B. Transgenic production of epoxy fatty acids by expression of a cytochrome P450 enzyme from Euphorbia lagascae seed. Plant Physiol. 2002;128:615-24 pubmed
..Overall, these results conclusively demonstrate that Asteraceae species and the Euphorbiaceae E. lagascae have evolved structurally unrelated enzymes to generate the Delta(12)-epoxy group of vernolic acid. ..