Yizheng Zhu

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Spectral-domain differential interference contrast microscopy
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 36:430-2. 2011
  2. pmc Angle-resolved low-coherence interferometry: an optical biopsy technique for clinical detection of dysplasia in Barrett's esophagus
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, NC 27708, USA
    Expert Rev Gastroenterol Hepatol 6:37-41. 2012
  3. pmc Design and validation of an angle-resolved low-coherence interferometry fiber probe for in vivo clinical measurements of depth-resolved nuclear morphology
    Yizheng Zhu
    Duke University, Department of Biomedical Engineering, 136 Hudson Hall, Durham, North Carolina 27708, USA
    J Biomed Opt 16:011003. 2011
  4. pmc Detection of intestinal dysplasia using angle-resolved low coherence interferometry
    Neil Terry
    Duke University, Department of Biomedical Engineering, 136 Hudson Hall, Durham, North Carolina 27708, USA
    J Biomed Opt 16:106002. 2011
  5. pmc Fiber-optic interferometric two-dimensional scattering-measurement system
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 35:1641-3. 2010
  6. pmc Size and shape determination of spheroidal scatterers using two-dimensional angle resolved scattering
    Michael Giacomelli
    Dept of Biomedical Engineering and Fitzpatrick Center for Photonics, Duke University, Durham, NC 27708, USA
    Opt Express 18:14616-26. 2010
  7. pmc Detection of dysplasia in Barrett's esophagus with in vivo depth-resolved nuclear morphology measurements
    Neil G Terry
    Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA
    Gastroenterology 140:42-50. 2011
  8. doi request reprint Observation of interference in a fiber taper interferometer with a subwavelength tip and its sensing applications
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 34:2808-10. 2009
  9. pmc Scanning fiber angle-resolved low coherence interferometry
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 34:3196-8. 2009
  10. pmc Phase-sensitive OCT imaging of multiple nanoparticle species using spectrally multiplexed single pulse photothermal excitation
    Sanghoon Kim
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Biomed Opt Express 3:2579-86. 2012

Collaborators

  • Adam Wax
  • Matthew T Rinehart
  • Natan T Shaked
  • Evan S Dellon
  • Sanghoon Kim
  • Neil Terry
  • Neil G Terry
  • Michael Giacomelli
  • Hansang Park
  • Ryan D Madanick
  • Elizabeth Carretta
  • John R Goldblum
  • Bergein F Overholt
  • Nicholas J Shaheen
  • John Migaly
  • Masoud Panjehpour
  • Christopher R Mantyh
  • Steven C Gebhart
  • Stephanie Bright
  • Dimitri Trembath
  • Joseph Galanko
  • William J Brown
  • Cynthia Guy
  • John T Woosley
  • Courtney G Ziefle
  • Ana Bennett
  • Julie K M Thacker
  • John Lee

Detail Information

Publications13

  1. pmc Spectral-domain differential interference contrast microscopy
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 36:430-2. 2011
    ..Live cardiomyocytes were also imaged, achieving a resolution of 36 pm for pathlength gradient measurements. The dynamics of cardiomyocyte contraction were recorded with high sensitivity at selected sites on the cells...
  2. pmc Angle-resolved low-coherence interferometry: an optical biopsy technique for clinical detection of dysplasia in Barrett's esophagus
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, NC 27708, USA
    Expert Rev Gastroenterol Hepatol 6:37-41. 2012
    ..In a recent clinical study of 46 Barrett's esophagus patients, a/LCI was able to detect dysplasia with 100% sensitivity and 84% specificity. This report reviews the technique and discusses its potential clinical utility...
  3. pmc Design and validation of an angle-resolved low-coherence interferometry fiber probe for in vivo clinical measurements of depth-resolved nuclear morphology
    Yizheng Zhu
    Duke University, Department of Biomedical Engineering, 136 Hudson Hall, Durham, North Carolina 27708, USA
    J Biomed Opt 16:011003. 2011
    ..Initial results from a clinical feasibility test are also presented to show in vivo application in the human esophagus...
  4. pmc Detection of intestinal dysplasia using angle-resolved low coherence interferometry
    Neil Terry
    Duke University, Department of Biomedical Engineering, 136 Hudson Hall, Durham, North Carolina 27708, USA
    J Biomed Opt 16:106002. 2011
    ..6% (56/67), and an overall accuracy of 85.2% (69/81). The study illustrates the extension of the a/LCI technique to the detection of intestinal dysplasia, and demonstrates the need for future in vivo studies...
  5. pmc Fiber-optic interferometric two-dimensional scattering-measurement system
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 35:1641-3. 2010
    ..Experimental data from samples with different sizes and acquired with different polarizations show excellent agreement with Mie theory, producing structural measurements with subwavelength accuracy...
  6. pmc Size and shape determination of spheroidal scatterers using two-dimensional angle resolved scattering
    Michael Giacomelli
    Dept of Biomedical Engineering and Fitzpatrick Center for Photonics, Duke University, Durham, NC 27708, USA
    Opt Express 18:14616-26. 2010
    ..T-matrix based inverse analysis of these two-dimensional angular measurements yields completely unique size and aspect ratio determinations with subwavelength precision over a large range of possible scatterer geometries...
  7. pmc Detection of dysplasia in Barrett's esophagus with in vivo depth-resolved nuclear morphology measurements
    Neil G Terry
    Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA
    Gastroenterology 140:42-50. 2011
    ..Angle-resolved low coherence interferometry (a/LCI) uses in vivo depth-resolved nuclear morphology measurements to detect dysplasia. We assessed the clinical utility of a/LCI in the endoscopic surveillance of patients with BE...
  8. doi request reprint Observation of interference in a fiber taper interferometer with a subwavelength tip and its sensing applications
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 34:2808-10. 2009
    ..The interferometer's sensing application is demonstrated by the effective measurement of refractive index and temperature...
  9. pmc Scanning fiber angle-resolved low coherence interferometry
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 34:3196-8. 2009
    ..We characterize the optical performance of the probe and demonstrate the ability to execute depth-resolved sizing with subwavelength accuracy by using a double-layer phantom containing two sizes of polystyrene microspheres...
  10. pmc Phase-sensitive OCT imaging of multiple nanoparticle species using spectrally multiplexed single pulse photothermal excitation
    Sanghoon Kim
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Biomed Opt Express 3:2579-86. 2012
    ..In addition, we characterize single-pulse excitation schemes as a method to minimize bulk heating of the sample. We demonstrate this new scheme with B-mode photothermal measurements of tissue phantoms...
  11. pmc Development of angle-resolved low coherence interferometry for clinical detection of dysplasia
    Yizheng Zhu
    Department of Biomedical Engineering, Duke University, Durham, NC, USA
    J Carcinog 10:19. 2011
    ..Here, the various implementations of a/LCI are discussed and the results of the preliminary animal experiments and ex vivo human tissue studies are reviewed. A review of a recent in vivo clinical study is also presented...
  12. pmc Quantitative phase spectroscopy
    Matthew Rinehart
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Biomed Opt Express 3:958-65. 2012
    ..Considerations of using low coherence illumination and the extension of spectral techniques in quantitative phase measurements are discussed...
  13. doi request reprint Two-step-only phase-shifting interferometry with optimized detector bandwidth for microscopy of live cells
    Natan T Shaked
    Department of Biomedical Engineering, Fitzpatrick Institute for Photonics, Duke University Durham, North Carolina 27708, USA
    Opt Express 17:15585-91. 2009
    ..Experimental and theoretical comparisons between the proposed method and these traditional interferometric approaches are given. The method is experimentally demonstrated via phase microscopy of live human skin cancer cells...