Research Topics
| S Yousuf ZafarSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
Chemotherapy use and patient treatment preferences in advanced colorectal cancer: a prospective cohort studyS Yousuf Zafar
Duke Cancer Institute, Durham, North Carolina 27710, USA
Cancer 119:854-62. 2013..The objective of this study was to determine how patient preferences guide the course of palliative chemotherapy for advanced colorectal cancer...
Consensus-based standards for best supportive care in clinical trials in advanced cancerS Yousuf Zafar
Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Lancet Oncol 13:e77-82. 2012..Availability of resources was cited as a challenge to implementation of best supportive care standards...
Malignancy after solid organ transplantation: an overviewS Yousuf Zafar
Divisions of Hematology and Medical Oncology, Duke University Medical Center, 508 Fulton Street 152, Durham, North Carolina 27705, USA
Oncologist 13:769-78. 2008..Treatment involves modification of the immunosuppressive drug regimen, resection of localized disease, and chemotherapy. We present the second reported case of a patient with lung transplantation who developed KS in the lung graft...
Early dissemination of bevacizumab for advanced colorectal cancer: a prospective cohort studyS Yousuf Zafar
Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
BMC Cancer 11:354. 2011..We describe early dissemination patterns for first-line bevacizumab given for metastatic colorectal cancer treatment...
Standards for palliative care delivery in oncology settingsS Yousuf Zafar
Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC 27701, USA
Cancer J 16:436-43. 2010..Guideline efficacy has not been evaluated, and their dissemination into standard care has been poor. A conceptual framework for better implementation of existing guidelines might improve usage and outcomes...
Treatment-related toxicity and supportive care in metastatic colorectal cancerS Yousuf Zafar
Division of Medical Oncology, Department of Medicine, Duke University Medical Center, 2424 Erwin Road, Suite G05, Hock Plaza, DUMC Box 2732, Durham, NC 27710, USA
J Support Oncol 8:15-20. 2010..These data, obtained from a usual-practice setting, provide benchmarks to improve clinical practice...
Decision making and quality of life in the treatment of cancer: a reviewS Yousuf Zafar
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Support Care Cancer 17:117-27. 2009..We present an overview of the literature related to patient and physician decision making and quality of life in patients with advanced cancer, and we propose approaches to future decision-making models in cancer treatment...
Comorbidity, age, race and stage at diagnosis in colorectal cancer: a retrospective, parallel analysis of two health systemsS Yousuf Zafar
Department of Medicine, Duke University Medical Center, Durham, USA
BMC Cancer 8:345. 2008..The objective of this study is to investigate how comorbidity, race and age influence stage of CRC diagnosis...
Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumorsJohn H Strickler
Duke University Medical Center, Durham, NC 27710, USA
Cancer Chemother Pharmacol 70:251-8. 2012..To define the maximum tolerated dose, clinical toxicities, and pharmacodynamics of bevacizumab, everolimus, and panobinostat (LBH-589) when administered in combination to patients with advanced solid tumor malignancies...
A phase II trial of bevacizumab plus everolimus for patients with refractory metastatic colorectal cancerIvy Altomare
Duke University Medical Center, Durham, North Carolina, USA
Oncologist 16:1131-7. 2011..A phase I study of bevacizumab plus everolimus demonstrated that the combination is safe; activity was seen in several patients with refractory mCRC...
A Phase II Study of Capecitabine, Oxaliplatin, and Bevacizumab in the Treatment of Metastatic Esophagogastric AdenocarcinomasHope E Uronis
Duke Cancer Institute, Durham, North Carolina, USA
Oncologist 18:271-2. 2013..The combination of capecitabine, oxaliplatin, plus bevacizumab has activity comparable to other bevacizumab-containing regimens in metastatic gastroesophageal cancer...
Electronic patient-reported data capture as a foundation of rapid learning cancer careAmy P Abernethy
Division of Medical Oncology, Department of Medicine, Duke University Health System, Duke University Medical Center DUMC, Durham, NC 27710, USA
Med Care 48:S32-8. 2010....
A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumorsGordana Vlahovic
Duke University Medical Center, Seeley G Mudd Bldg, 10 Bryan Searle Drive, Box 3052, Durham, NC 27710, USA
Cancer Chemother Pharmacol 70:95-102. 2012..This study evaluated the maximum tolerated dose/recommended phase II dose and safety and tolerability of bevacizumab, everolimus and panitumumab drug combination...
Management of gastrointestinal symptoms in advanced cancer patients: the rapid learning cancer clinic modelAmy P Abernethy
Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
Curr Opin Support Palliat Care 4:36-45. 2010....
Quality of nonmetastatic colorectal cancer care in the Department of Veterans AffairsGeorge L Jackson
Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
J Clin Oncol 28:3176-81. 2010..We measured the quality of nonmetastatic colorectal cancer (CRC) care in VA as indicated by concordance with National Comprehensive Cancer Network practice guidelines (six indicators) and timeliness of care (three indicators)...
Longitudinal patterns of chemotherapy use in metastatic colorectal cancerS Yousuf Zafar
Cancer Center Biostatistics Division of Medical Oncology, Department of Medicine and Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC
J Oncol Pract 5:228-33. 2009....
A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE)Karen E Bullock
Duke University Medical Center, Seeley G Mudd Bldg, 10 Bryan Searle Drive, Box 3052, Durham, NC 27710, USA
Cancer Chemother Pharmacol 67:465-74. 2011..This study evaluated the safety, tolerability, and pharmacokinetics of bevacizumab, everolimus, and erlotinib combination...
Quality management of potential chemotherapy-induced neutropenic complications: evaluation of practice in an academic medical centerAmy P Abernethy
Department of Medicine, Division of Medical Oncology, Duke University Medical Center DUMC, Box 3436, Durham, NC 27710, USA
Support Care Cancer 17:735-44. 2009..How frequently does care at our institution conform to established guidelines?..
Use of tablet personal computers for sensitive patient-reported informationAlexandra Dupont
Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina, USA
J Support Oncol 7:91-7. 2009..The e/Tablet electronic system may provide a "safer" environment than paper questionnaires for cancer patients to answer private or highly personal questions on sensitive topics such as sexuality...
Detailing of gastrointestinal symptoms in cancer patients with advanced disease: new methodologies, new insights, and a proposed approachAmy P Abernethy
Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
Curr Opin Support Palliat Care 3:41-9. 2009....
The Financial Toxicity of Cancer Treatment: A Pilot Study Assessing Out-of-Pocket Expenses and the Insured Cancer Patient's ExperienceS Yousuf Zafar
Center for Learning Health Care, Duke Clinical Research Institute Division of Medical Oncology and Department of Medicine, Duke Cancer Institute, Durham, North Carolina, USA
Oncologist 18:381-90. 2013..Future research should investigate coverage thresholds that minimize adverse financial outcomes and identify cancer patients at greatest risk for financial toxicity...
Carcinoma of the ampulla of Vater: patterns of failure following resection and benefit of chemoradiotherapyManisha Palta
Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA
Ann Surg Oncol 19:1535-40. 2012..Despite radical resection, survival rates remain low with high rates of local failure. We performed a single-institution outcomes analysis to define the role of concurrent chemoradiotherapy (CRT) in addition to surgery...
A strategy to advance the evidence base in palliative medicine: formation of a palliative care research cooperative groupAmy P Abernethy
Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
J Palliat Med 13:1407-13. 2010....
