Research Topics
| W S YancySummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
Hypertension Improvement Project (HIP): study protocol and implementation challengesRowena J Dolor
Department of Medicine, Duke University Medical Center, Durham, NC, USA
Trials 10:13. 2009..The chronic care model suggests that blood pressure control can be achieved by improving how patients and physicians address patient self-care...
Study protocol: Couples Partnering for Lipid Enhancing Strategies (CouPLES) - a randomized, controlled trialCorrine I Voils
Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, North Carolina, USA
Trials 10:10. 2009....
The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitusEric C Westman
Department of Medicine, Duke University Medical Center, Durham, NC, USA
Nutr Metab (Lond) 5:36. 2008..In this study, we tested the hypothesis that a diet lower in carbohydrate would lead to greater improvement in glycemic control over a 24-week period in patients with obesity and type 2 diabetes mellitus...
Relationship between obesity and health-related quality of life in menWilliam S Yancy
Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, Durham, North Carolina, USA
Obes Res 10:1057-64. 2002..Furthermore, most studies have not adequately considered comorbid illness. The goal of this study was to examine the relationship between body mass index (BMI) and HRQOL in male outpatients while considering comorbid illness...
A randomized trial of a low-carbohydrate diet vs orlistat plus a low-fat diet for weight lossWilliam S Yancy
Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, Durham, North Carolina, USA
Arch Intern Med 170:136-45. 2010..Two potent weight loss therapies, a low-carbohydrate, ketogenic diet (LCKD) and orlistat therapy combined with a low-fat diet (O + LFD), are available to the public but, to our knowledge, have never been compared...
Acid-base analysis of individuals following two weight loss dietsW S Yancy
Department of Veterans Affairs Medical Center, Center for Health Services Research in Primary Care, Durham, NC 27705, USA
Eur J Clin Nutr 61:1416-22. 2007..To examine the effects of low-carbohydrate, ketogenic (LCKD) and low-fat (LFD) diets on acid-base status...
Effects of two weight-loss diets on health-related quality of lifeWilliam S Yancy
Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, 508 Fulton Street, Durham, NC, 27705, USA
Qual Life Res 18:281-9. 2009..To compare the effects of two diets on health-related quality of life (HRQOL)...
Variations in coronary procedure utilization depending on body mass indexWilliam S Yancy
Center for Health Services Research in Primary Care, Veterans Affairs Medical Center, Durham, NC 27705, USA
Arch Intern Med 165:1381-7. 2005..The relationship between BMI and utilization of diagnostic or therapeutic procedures for coronary heart disease has not been examined...
Patient satisfaction in resident and attending ambulatory care clinicsW S Yancy
Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, Duke University Medical Center, Durham, NC 27705, USA
J Gen Intern Med 16:755-62. 2001..To measure and compare patient satisfaction with care in resident and attending physician internal medicine ambulatory care clinics...
Obesity and receipt of clinical preventive services in veteransWilliam S Yancy
Department of Veterans Affairs Medical Center, Center for Health Services Research in Primary Care, Durham, North Carolina, USA
Obesity (Silver Spring) 18:1827-35. 2010..This may be due to the VA health service coverage and performance directives, a more homogeneous patient demographic profile, and/or unmeasured factors related to service receipt...
A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia: a randomized, controlled trialWilliam S Yancy
Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, and Duke University Medical Center, Durham, North Carolina 27705, USA
Ann Intern Med 140:769-77. 2004..During active weight loss, serum triglyceride levels decreased more and high-density lipoprotein cholesterol level increased more with the low-carbohydrate diet than with the low-fat diet...
Diet therapy for narcolepsyA M Husain
Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Neurology 62:2300-2. 2004..The NSSQ-Total score decreased by 18% from 161.9 to 133.5 (p = 0.0019) over 8 weeks. Patients with narcolepsy experienced modest improvements in daytime sleepiness on an LCKD...
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistanceChristopher B Newgard
Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
Cell Metab 9:311-26. 2009..Our findings show that in the context of a dietary pattern that includes high fat consumption, BCAA contributes to development of obesity-associated insulin resistance...
Low-carbohydrate nutrition and metabolismEric C Westman
Department of Medicine, Duke University Medical Center, Durham, NC 27704, USA
Am J Clin Nutr 86:276-84. 2007....
Does participatory decision making improve hypertension self-care behaviors and outcomes?Alex H Cho
Center for Health Services Research in Primary Care, Vetterans Affairs Medical Center, Durham, NC 27705, USA
J Clin Hypertens (Greenwich) 9:330-6. 2007..No relationship between PDM score and blood pressure control was observed...
Carbohydrate-restricted diets for obesity and related diseases: an updateChristy L Boling
Center for Health Services Research in Primary Care, Veterans Affairs Medical Center 152, Durham, NC 27705, USA
Curr Atheroscler Rep 11:462-9. 2009..This review synthesizes important clinical and physiologic studies on CRDs published between January 2007 and May 2009...
Physician characteristics as predictors of blood pressure control in patients enrolled in the hypertension improvement project (HIP)Leonor Corsino
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
J Clin Hypertens (Greenwich) 13:106-11. 2011..Given the increasing time demands on physicians, future research should examine how physicians with a busy practice are able to successfully address BP in their patients...
A multidimensional integrative medicine intervention to improve cardiovascular riskDavid Edelman
Division of General Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, NC, USA
J Gen Intern Med 21:728-34. 2006..Our objective was to determine whether personalized health planning (PHP), an intervention based on the theories and principles underlying integrative medicine, reduces 10-year risk of coronary heart disease (CHD)...
Dietary treatment of diabetes mellitus in the pre-insulin era (1914-1922)Eric C Westman
Division of General Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
Perspect Biol Med 49:77-83. 2006..A reconsideration of the role of the high-fat, low-carbohydrate diet for the treatment of diabetes mellitus is in order...
Effect of 6-month adherence to a very low carbohydrate diet programEric C Westman
Division of General Internal Medicine, Duke University, 2200 West Main Street, Durham, NC 27705, USA
Am J Med 113:30-6. 2002..A very low carbohydrate diet program led to sustained weight loss during a 6-month period. Further controlled research is warranted...
A review of low-carbohydrate ketogenic dietsEric C Westman
Department of Medicine, Duke University Medical Center, Box 50, Suite 200 B Wing, 2200 West Main Street, Durham, NC 27705, USA
Curr Atheroscler Rep 5:476-83. 2003..This review summarizes the physiology and recent clinical studies regarding this type of diet...
Improving the measurement of self-reported medication nonadherenceCorrine I Voils
Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
J Clin Epidemiol 64:250-4. 2011..We demonstrate how two fundamental measurement issues have limited the usefulness of self-reported medication nonadherence measures and offer recommendations for improving measurement...
Associations between obesity and receipt of screening mammography, Papanicolaou tests, and influenza vaccination: results from the Health and Retirement Study (HRS) and the Asset and Health Dynamics Among the Oldest Old (AHEAD) StudyTruls Østbye
Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am J Public Health 95:1623-30. 2005..We evaluated the association between body mass index (BMI) and receipt of screening mammography and Papanicolaou tests among middle-aged women and the association between BMI and receipt of influenza vaccination among the elderly...
Elevated body mass index and intermediate-term clinical outcomes after acute coronary syndromesEric L Eisenstein
Duke University Medical Center and the Duke Clinical Research Institute, Durham, NC 27715, USA
Am J Med 118:981-90. 2005..We evaluated the relationship between elevated body mass index (BMI) and 30-day, 90-day, and 1-year clinical outcomes postacute coronary syndromes...
Effect of a low-carbohydrate, ketogenic diet program compared to a low-fat diet on fasting lipoprotein subclassesEric C Westman
Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
Int J Cardiol 110:212-6. 2006..Low-carbohydrate, ketogenic diets (LCKD) are effective for weight loss, but concerns remain regarding cardiovascular risk. The purpose of this study was to determine the effect of an LCKD program on serum lipoprotein subclasses...
Do diabetic veterans use the Internet? Self-reported usage, skills, and interest in using My HealtheVet Web portalAlex H Cho
Division of General Internal Medicine, Duke University, Durham, North Carolina 27710, USA
Telemed J E Health 16:595-602. 2010..The objective of this study was to measure diabetic veterans' access to and use of the Internet, and their interest in using MHV to help manage their diabetes...
Hypertension improvement project: randomized trial of quality improvement for physicians and lifestyle modification for patientsLaura P Svetkey
Department of Medicine, Duke University Medical Center, Durham, NC, USA
Hypertension 54:1226-33. 2009..Differences between treatment groups did not persist at 18 months. Combined physician and patient interventions lowers blood pressure; future research should focus on enhancing effectiveness and sustainability of these interventions...
Obesity prevalence among veterans at Veterans Affairs medical facilitiesSandeep R Das
Preventive Medicine Residency Program, Department of Social Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Prev Med 28:291-4. 2005..8%) and men (20.6%) had the lowest. CONCLUSIONS: There is a substantial burden of obesity among veterans using VA medical facilities. A comprehensive approach for weight management by the Veterans Health Administration is needed...
The effects of a low-carbohydrate ketogenic diet and a low-fat diet on mood, hunger, and other self-reported symptomsF Joseph McClernon
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Suite 210 B Wing, 2200 West Main Street, Durham, NC 27705, USA
Obesity (Silver Spring) 15:182-7. 2007..To investigate the effects of weight loss diets on mood, food cravings, and other self-reported symptoms...
Residential smoking therapyAmanda Green
Received from Ambulatory Care Service, Durham VA Medical Center, Durham, NC 27705, USA
J Gen Intern Med 18:275-80. 2003..Four days of residential smoking therapy successfully relieved smoking withdrawal. At 6 months after discharge, participants maintained an abstinence rate comparable to other medical therapies for smoking...
Diets and clinical coronary events: the truth is out thereWilliam S Yancy
Division of General Medicine, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Circulation 107:10-6. 2003
The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot studyDavid Tendler
Division of Gastroenterology, Department of Medicine, Duke University Health System, Durham, NC, USA
Dig Dis Sci 52:589-93. 2007..02) inflammatory grade (P=.02), and fibrosis (P=.07). Six months of a low-carbohydrate, ketogenic diet led to significant weight loss and histologic improvement of fatty liver disease. Further research is into this approach is warranted...
Improvement of gastroesophageal reflux disease after initiation of a low-carbohydrate diet: five brief case reportsW S Yancy
Center for Health Services Research in Primary Care, Veterans' Affairs Medical Center, Division of General Medicine, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Altern Ther Health Med 7:120, 116-9. 2001..Trials that control for all of the confounders mentioned above and that contain objective endpoints are needed to further investigate these issues...
A very low-carbohydrate diet improves gastroesophageal reflux and its symptomsGregory L Austin
Division of Gastroenterology and Hepatology and the Center for Esophageal Diseases and Swallowing, University of North Carolina, Chapel Hill, North Carolina, USA
Dig Dis Sci 51:1307-12. 2006..5% (P=0.022). Mean GSAS-ds score decreased from 1.28 to 0.72 (P=0.0004). These data suggest that a very low-carbohydrate diet in obese individuals with GERD significantly reduces distal esophageal acid exposure and improves symptoms...
Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trialsAlain J Nordmann
Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, CH 4031 Basel, Switzerland
Arch Intern Med 166:285-93. 2006..Low-carbohydrate diets have become increasingly popular for weight loss. However, evidence from individual trials about benefits and risks of these diets to achieve weight loss and modify cardiovascular risk factors is preliminary...
Is a low-carb, low-fat diet optimal?Eric C Westman
Arch Intern Med 165:1071-2. 2005
Nonfasting triglycerides and cardiovascular riskWilliam S Yancy
JAMA 298:2004; author reply 2005-6. 2007
