John W Williams

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Systems for grading the quality of evidence and the strength of recommendations II: pilot study of a new system
    David Atkins
    Center for Practice and Technology Assessment, Agency for Healthcare Research and Quality, 540 Gaither Rd Rokville, MD 20852, USA
    BMC Health Serv Res 5:25. 2005
  2. pmc Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group
    David Atkins
    Center for Practice and Technology Assessment, Agency for Healthcare Research and Quality, 540 Gaither Rd Rockville, MD 20852, USA
    BMC Health Serv Res 4:38. 2004
  3. doi request reprint How reviews covered the unfolding scientific story of gabapentin for bipolar disorder
    John W Williams
    Center for Health Services Research in Primary Care, Durham VAMC and Center for Clinical Health Policy Research, Duke University, Durham, NC 27705, USA
    Gen Hosp Psychiatry 31:279-87. 2009
  4. ncbi request reprint Identifying depression in primary care: a literature synthesis of case-finding instruments
    John W Williams
    The South Texas Veterans Health Care System, Audie Murphy Division Veterans Evidence based Research Dissemination and Implementation, San Antonio, TX, USA
    Gen Hosp Psychiatry 24:225-37. 2002
  5. ncbi request reprint Is this patient clinically depressed?
    John W Williams
    Department of Veterans Affairs Medical Center, 508 Fulton St, HSR and D, Bldg 6, Durham, NC 27705, USA
    JAMA 287:1160-70. 2002
  6. ncbi request reprint Systematic review of multifaceted interventions to improve depression care
    John W Williams
    Center for Health Services Research in Primary Care, Durham VA Medical Center, Durham, NC, USA
    Gen Hosp Psychiatry 29:91-116. 2007
  7. ncbi request reprint The 13- and 20-item Hopkins Symptom Checklist Depression Scale: psychometric properties in primary care patients with minor depression or dysthymia
    John W Williams
    Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, Duke University Medical Center, Durham, North Carolina 27705, USA
    Int J Psychiatry Med 34:37-50. 2004
  8. doi request reprint Screening for cognitive impairment: comparing the performance of four instruments in primary care
    Tracey Holsinger
    Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, North Carolina, USA
    J Am Geriatr Soc 60:1027-36. 2012
  9. ncbi request reprint Improving depression outcomes in older adults with comorbid medical illness
    Linda H Harpole
    Department of Medicine, Duke University Medical Center, Durham, NC 27709, USA
    Gen Hosp Psychiatry 27:4-12. 2005
  10. pmc Depression and comorbid illness in elderly primary care patients: impact on multiple domains of health status and well-being
    Polly Hitchcock Noel
    VERDICT, an HSR and D Center of Excellence, South Texas Veterans Health Care System, 7400 Merton Minter Blvd 11C6, San Antonio, TX 78229 4404, USA
    Ann Fam Med 2:555-62. 2004

Detail Information

Publications54

  1. pmc Systems for grading the quality of evidence and the strength of recommendations II: pilot study of a new system
    David Atkins
    Center for Practice and Technology Assessment, Agency for Healthcare Research and Quality, 540 Gaither Rd Rokville, MD 20852, USA
    BMC Health Serv Res 5:25. 2005
    ..The GRADE Working Group has developed an approach that addresses key shortcomings in these systems. The aim of this study was to pilot test and further develop the GRADE approach to grading evidence and recommendations...
  2. pmc Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group
    David Atkins
    Center for Practice and Technology Assessment, Agency for Healthcare Research and Quality, 540 Gaither Rd Rockville, MD 20852, USA
    BMC Health Serv Res 4:38. 2004
    ....
  3. doi request reprint How reviews covered the unfolding scientific story of gabapentin for bipolar disorder
    John W Williams
    Center for Health Services Research in Primary Care, Durham VAMC and Center for Clinical Health Policy Research, Duke University, Durham, NC 27705, USA
    Gen Hosp Psychiatry 31:279-87. 2009
    ..Subsequent RCTs did not demonstrate efficacy for bipolar disorder (BD). We examined the characteristics of review articles to determine their potential role in the growth of gabapentin for BD...
  4. ncbi request reprint Identifying depression in primary care: a literature synthesis of case-finding instruments
    John W Williams
    The South Texas Veterans Health Care System, Audie Murphy Division Veterans Evidence based Research Dissemination and Implementation, San Antonio, TX, USA
    Gen Hosp Psychiatry 24:225-37. 2002
    ....
  5. ncbi request reprint Is this patient clinically depressed?
    John W Williams
    Department of Veterans Affairs Medical Center, 508 Fulton St, HSR and D, Bldg 6, Durham, NC 27705, USA
    JAMA 287:1160-70. 2002
    ..Depressive disorders are highly prevalent in the general population, but recognition and accurate diagnosis are made difficult by the lack of a simple confirmatory test...
  6. ncbi request reprint Systematic review of multifaceted interventions to improve depression care
    John W Williams
    Center for Health Services Research in Primary Care, Durham VA Medical Center, Durham, NC, USA
    Gen Hosp Psychiatry 29:91-116. 2007
    ....
  7. ncbi request reprint The 13- and 20-item Hopkins Symptom Checklist Depression Scale: psychometric properties in primary care patients with minor depression or dysthymia
    John W Williams
    Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, Duke University Medical Center, Durham, North Carolina 27705, USA
    Int J Psychiatry Med 34:37-50. 2004
    ..We evaluated the psychometric properties and responsiveness to clinical change of the 13- and 20-item versions of the Hopkins Symptom Checklist Depression Scale (HSCL-D)...
  8. doi request reprint Screening for cognitive impairment: comparing the performance of four instruments in primary care
    Tracey Holsinger
    Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, North Carolina, USA
    J Am Geriatr Soc 60:1027-36. 2012
    ..To determine whether brief cognitive screening tests perform as well as a longer screening test in diagnosis of cognitive impairment, no dementia (CIND) or dementia...
  9. ncbi request reprint Improving depression outcomes in older adults with comorbid medical illness
    Linda H Harpole
    Department of Medicine, Duke University Medical Center, Durham, NC 27709, USA
    Gen Hosp Psychiatry 27:4-12. 2005
    ..Depression is common in older adults and often coexists with multiple chronic diseases, which may complicate its diagnosis and treatment...
  10. pmc Depression and comorbid illness in elderly primary care patients: impact on multiple domains of health status and well-being
    Polly Hitchcock Noel
    VERDICT, an HSR and D Center of Excellence, South Texas Veterans Health Care System, 7400 Merton Minter Blvd 11C6, San Antonio, TX 78229 4404, USA
    Ann Fam Med 2:555-62. 2004
    ....
  11. pmc The challenges of multimorbidity from the patient perspective
    Polly Hitchcock Noel
    VERDICT South Texas Veterans Healthcare System, 7400 Merton Minter Blvd, San Antonio, TX, USA
    J Gen Intern Med 22:419-24. 2007
    ..Although multiple co-occurring chronic illnesses within the same individual are increasingly common, few studies have examined the challenges of multimorbidity from the patient perspective...
  12. doi request reprint An evidence synthesis of care models to improve general medical outcomes for individuals with serious mental illness: a systematic review
    Daniel W Bradford
    Psychosocial Rehabilitation and Recovery Center, Durham VA Medical Center, 1830 Hillandale Rd, Durham, NC 27705
    J Clin Psychiatry 74:e754-64. 2013
    ..To conduct a systematic review of studies of interventions that integrated medical and mental health care to improve general medical outcomes in individuals with serious mental illness...
  13. ncbi request reprint Pharmacologic and behavioral interventions to improve cardiovascular risk factors in adults with serious mental illness: a systematic review and meta-analysis
    Jennifer M Gierisch
    Center for Health Services Research in Primary Care, Durham Veteran Affairs Medical Center 152, 508 Fulton St, Durham, NC 27705
    J Clin Psychiatry 75:e424-40. 2014
    ..This systematic review was conducted to evaluate pharmacologic and behavioral interventions to reduce CVD risk in adults with serious mental illness...
  14. pmc Systematic review of disease-modifying antirheumatic drugs for juvenile idiopathic arthritis
    Alex R Kemper
    Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA
    BMC Pediatr 12:29. 2012
    ..g., non-steroidal anti-inflammatory drugs, intra-articular corticosteroids). The purpose of this systematic review was to evaluate the comparative effectiveness and safety of DMARDs versus conventional therapy and versus other DMARDs...
  15. doi request reprint Percutaneous heart valve replacement for aortic stenosis: state of the evidence
    Remy R Coeytaux
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
    Ann Intern Med 153:314-24. 2010
    ..Pending publication of findings from that trial, the available evidence is inadequate to determine the most appropriate clinical role of PHVR or the specific patient populations for whom it might eventually be indicated...
  16. doi request reprint Acceptability of dementia screening in primary care patients
    Tracey Holsinger
    Durham VA Medical Center, Duke University Medical Center, Durham, NC, USA
    Int J Geriatr Psychiatry 26:373-9. 2011
    ..To determine the acceptability of dementia screening in two populations of older adults in different primary care settings...
  17. doi request reprint ECG-based signal analysis technologies for evaluating patients with acute coronary syndrome: a systematic review
    Philip J Leisy
    Duke Evidence Based Practice Center, Duke Clinical Research Institute, Duke University, Durham, NC, USA
    J Electrocardiol 46:92-7. 2013
    ..The first test is often the standard, resting 12-lead ECG. Given its limitations, signal analysis enhancements have been proposed. We summarize the published evidence for commercially available ECG-based signal analysis technologies...
  18. doi request reprint Psychometric characteristics of outcome measures in juvenile idiopathic arthritis: a systematic review
    Heather A van Mater
    Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA
    Arthritis Care Res (Hoboken) 64:554-62. 2012
    ....
  19. doi request reprint Depression and antidepressant use after stroke and transient ischemic attack
    Nada El Husseini
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Stroke 43:1609-16. 2012
    ..Patients with stroke and transient ischemic attack (TIA) often have comparable comorbidities, but it is unclear whether they have similar rates of depression or antidepressant use...
  20. doi request reprint Collaborative mental health and primary care for bipolar disorder
    John W Williams
    Duke University Medical Center, Durham VAMC, 2424 Erwin Road, Suite 1105, Durham, NC 27705, USA
    J Psychiatr Pract 14:55-64. 2008
    ..g., monitoring for weight gain, hyperglycemia, hyperlipidemia), and provision of bipolar-specific psychoeducation...
  21. ncbi request reprint The effectiveness of depression care management on diabetes-related outcomes in older patients
    John W Williams
    Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, and Duke University School of Medicine, Durham, North Carolina 27705, USA
    Ann Intern Med 140:1015-24. 2004
    ..Depression frequently occurs in combination with diabetes mellitus, adversely affecting the course of illness...
  22. ncbi request reprint Comparative effectiveness of warfarin and new oral anticoagulants for the management of atrial fibrillation and venous thromboembolism: a systematic review
    Soheir S Adam
    Duke University Medical Center, Department of Medicine, Box 3939, Durham, NC 27710, USA
    Ann Intern Med 157:796-807. 2012
    ..New oral anticoagulants (NOACs), including direct thrombin inhibitors (DTIs) and factor Xa (FXa) inhibitors, are emerging alternatives for prophylaxis and treatment of atrial fibrillation (AF) and venous thromboembolism (VTE)...
  23. doi request reprint Effect of clinical decision-support systems: a systematic review
    Tiffani J Bright
    Duke Evidence Based Practice Center, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
    Ann Intern Med 157:29-43. 2012
    ..Despite increasing emphasis on the role of clinical decision-support systems (CDSSs) for improving care and reducing costs, evidence to support widespread use is lacking...
  24. pmc Smoking cessation interventions for patients with depression: a systematic review and meta-analysis
    Jennifer M Gierisch
    Center for Health Services Research in Primary Care, Durham Veteran Affairs Medical Center 152, 508 Fulton Street, Durham, NC 27705, USA
    J Gen Intern Med 27:351-60. 2012
    ..e., history positive vs. current depression), and differential effects by gender...
  25. doi request reprint Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life
    Brenda L Plassman
    Duke University Medical Center, Durham, North Carolina 27701, USA
    Ann Intern Med 153:182-93. 2010
    ..Many biological, behavioral, social, and environmental factors may contribute to the delay or prevention of cognitive decline...
  26. pmc Identifying depressed older adults in primary care: a secondary analysis of a multisite randomized controlled trial
    Corrine I Voils
    Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, and the Department of Medicine, Division of General Internal Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Prim Care Companion J Clin Psychiatry 10:9-14. 2008
    ..To determine whether a subset of depressive symptoms could be identified to facilitate diagnosis of depression in older adults in primary care...
  27. ncbi request reprint Serving the health needs of our military and veterans
    John W Williams
    Duke University Medical Center, Durham, NC, USA
    N C Med J 69:23-6. 2008
  28. ncbi request reprint Does this patient have dementia?
    Tracey Holsinger
    Department of Psychiatry, Durham VA Medical Center, Durham, NC, USA
    JAMA 297:2391-404. 2007
    ..While as many as 5 million individuals in the United States have dementia, many others have memory complaints. Brief tests to screen for cognitive impairment could help guide dementia diagnosis...
  29. ncbi request reprint Sustainable impact of a primary care depression intervention
    Pamela W Lee
    Dartmouth Medical School, Hanover, NH, USA
    J Am Board Fam Med 20:427-33. 2007
    ..The purpose of this study was to determine whether an integrated model of depression management continued to be used by primary care clinicians after the end of a randomized controlled trial (RCT)...
  30. ncbi request reprint A fidelity measure for integrated management of depression in primary care
    Thomas E Oxman
    Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Med Care 44:1030-7. 2006
    ..Integrated models of primary care depression management improve outcomes. Subsequent dissemination efforts and their evaluation need a fidelity measure...
  31. ncbi request reprint Predictors of nonresponse to treatment in primary care patients with dysthymia
    Wayne Katon
    Department of Psychiatry and Behavioral Sciences, University of Washington Medical School, Seattle, WA, USA
    Gen Hosp Psychiatry 24:20-7. 2002
    ....
  32. ncbi request reprint Correlates of remission in primary care patients treated for minor depression
    Ellen Frank
    Department of Psychiatry, University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    Gen Hosp Psychiatry 24:12-9. 2002
    ..46) of being a patient in the VA system. The remaining variables associated with higher probability of remission appear to reflect social advantage and lower severity or complexity of illness...
  33. ncbi request reprint Preventing suicide in primary care patients: the primary care physician's role
    Herbert C Schulberg
    Weill Medical College, Cornell University, White Plains, NY 10605, USA
    Gen Hosp Psychiatry 26:337-45. 2004
    ....
  34. ncbi request reprint Improving depression care for older, minority patients in primary care
    Patricia A Arean
    Department of Psychiatry, University of California, San Francisco, California 94143, USA
    Med Care 43:381-90. 2005
    ..This study examines whether a collaborative care model for depression in primary care is as effective in older minorities as it is in nonminority elderly patients in improving depression treatment and outcomes...
  35. ncbi request reprint Low yield of thyroid-stimulating hormone testing in elderly patients with depression
    Shelagh A Fraser
    Regenstrief Institute and Indiana University, 1050 Wishard Boulevard, RG 6, Indianapolis, IN 46202, USA
    Gen Hosp Psychiatry 26:302-9. 2004
    ..37) or SCID score (P=.44). These findings should caution physicians against acceptance of borderline TSH values as the primary cause of a patient's clinical depression...
  36. ncbi request reprint Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial
    Jurgen Unutzer
    Center for Health Services Research, UCLA Neuropsychiatric Institute, 10920 Wilshire Blvd, Suite 300, Los Angeles, CA 90024, USA
    JAMA 288:2836-45. 2002
    ..Few depressed older adults receive effective treatment in primary care settings...
  37. ncbi request reprint Depression treatment in a sample of 1,801 depressed older adults in primary care
    Jurgen Unutzer
    Center for Health Services Research, UCLA Neuropsychiatric Institute, Los Angeles, California 90024, USA
    J Am Geriatr Soc 51:505-14. 2003
    ..To examine rates and predictors of lifetime and recent depression treatment in a sample of 1,801 depressed older primary care patients..
  38. ncbi request reprint Depression care attitudes and practices of newer obstetrician-gynecologists: a national survey
    Allen J Dietrich
    Department of Community and Family Medicine, Dartmouth Medical School, Hannover, NH 03755, USA
    Am J Obstet Gynecol 189:267-73. 2003
    ..The study was undertaken to assess attitudes and behavior of newer obstetricians/gynecologists in depression care...
  39. ncbi request reprint Patient beliefs predict response to paroxetine among primary care patients with dysthymia and minor depression
    Mark D Sullivan
    Department of Psychiatry, University of Washington, Seattle 98195, USA
    J Am Board Fam Pract 16:22-31. 2003
    ..Dysthymia and minor depression are common problems in primary care, but it is not known how patient health beliefs shape response to antidepressant treatment of these less severe forms of depression...
  40. ncbi request reprint Treatment of depression by mental health specialists and primary care physicians
    Allen J Dietrich
    JAMA 290:1991; author reply 1992-3. 2003
  41. ncbi request reprint A three-component model for reengineering systems for the treatment of depression in primary care
    Thomas E Oxman
    Department of Psychiatry, Dartmouth Medical School, NH 03756, USA
    Psychosomatics 43:441-50. 2002
    ..The three-component model is bound together by a common depression diagnostic and severity measure that facilitates communication and treatment decisions...
  42. ncbi request reprint Effect of improving depression care on pain and functional outcomes among older adults with arthritis: a randomized controlled trial
    Elizabeth H B Lin
    Center for Health Studies, Group Health Cooperative, Seattle, Wash 98101, USA
    JAMA 290:2428-9. 2003
    ..Depression and arthritis are disabling and common health problems in late life. Depression is also a risk factor for poor health outcomes among arthritis patients...
  43. pmc Rational treatment choices for non-major depressions in primary care: an evidence-based review
    Ronald T Ackermann
    Robert Wood Johnson Clinical Scholars Program, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, Wash, USA
    J Gen Intern Med 17:293-301. 2002
    ..Discussion is focused on premenstrual dysphoric disorder (PMDD) and minor depression because of their significant prevalence in the primary care setting and the lack of clear practice guidelines for addressing each illness...
  44. pmc Suicidal ideation and risk levels among primary care patients with uncomplicated depression
    Herbert C Schulberg
    Weill Medical College of Cornell University, White Plains, NY 10605, USA
    Ann Fam Med 3:523-8. 2005
    ..We investigated the prevalence, severity, and course of passive and active suicidal ideation occurring in primary care patients with an uncomplicated depressive disorder...
  45. pmc Going to scale: re-engineering systems for primary care treatment of depression
    Allen J Dietrich
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH 03755, USA
    Ann Fam Med 2:301-4. 2004
    ..Recent trials have shown improved depression outcomes with chronic care models. We report the methods of a project that assesses the sustainability and transportability of a chronic care model for depression and change strategy...
  46. ncbi request reprint Cost-effectiveness and net benefit of enhanced treatment of depression for older adults with diabetes and depression
    Wayne Katon
    Department of Psychiatry and Behavioral Sciences, Box 356560, University of Washington School of Medicine, 1959 NE Pacific St, Seattle, WA 98195 6560, USA
    Diabetes Care 29:265-70. 2006
    ..To determine the incremental cost-effectiveness and net benefit of a depression collaborative care program compared with usual care for patients with diabetes and depression...
  47. pmc Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care
    Enid M Hunkeler
    Kaiser Permanente, Division of Research, 2000 Broadway, 2nd Floor, Oakland, CA 94612, USA
    BMJ 332:259-63. 2006
    ..To determine the long term effectiveness of collaborative care management for depression in late life...
  48. ncbi request reprint Hispanic ethnicity, language, and depression: physician-patient communication and patient use of alternative treatments
    Betsy L Sleath
    University of North Carolina at Chapel Hill, Center for Health Services Research, NC 27599 3386, USA
    Int J Psychiatry Med 34:235-46. 2004
    ..To examine the relationship between Hispanic ethnicity and language spoken with physician communication about depression and patient use of alternative treatments for depression...
  49. ncbi request reprint Impact of pain on the outcomes of depression treatment: results from the RESPECT trial
    Kurt Kroenke
    Indiana University School of Medicine and Regenstrief Institute, 1050 Wishard Boulevard RG 6, Indianapolis, IN 46202 2859, USA
    Pain 134:209-15. 2008
    ..Pain is prevalent in patients with depression. The purpose of this study was to determine the impact of pain on depression treatment outcomes...
  50. ncbi request reprint St John's for depression, worts and all
    John W Williams
    BMJ 330:E350-1. 2005
  51. ncbi request reprint Adherence to mental health treatment in a primary care clinic
    Jodi Gonzalez
    VERDICT Center of Excellence, University of Texas Health Science Center at San Antonio, TX 78229 3900, USA
    J Am Board Fam Pract 18:87-96. 2005
    ..Patient nonadherence is common for the standard mental health treatments in primary care: antidepressants and referrals to specialty mental health treatment. This is one of few studies to prospectively identify predictors of nonadherence...
  52. ncbi request reprint Impact of comorbid panic and posttraumatic stress disorder on outcomes of collaborative care for late-life depression in primary care
    Mark T Hegel
    Center for Health Services Research, UCLA Neuropsychiatric Institute, Los Angeles, CA, USA
    Am J Geriatr Psychiatry 13:48-58. 2005
    ..The authors evaluated the effect of comorbid panic disorder and posttraumatic stress disorder (PTSD) on response to a collaborative-care intervention for late-life depression in primary care...
  53. pmc Re-engineering systems for the treatment of depression in primary care: cluster randomised controlled trial
    Allen J Dietrich
    Dartmouth Medical School, HB 7250, Hanover, NH 03755, USA
    BMJ 329:602. 2004
    ..To test the effectiveness of an evidence based model for management of depression in primary care with support from quality improvement resources...
  54. ncbi request reprint Reducing suicidal ideation in depressed older primary care patients
    Jurgen Unutzer
    Department of Psychiatry, School of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 54:1550-6. 2006
    ..To determine the effect of a primary care-based collaborative care program for depression on suicidal ideation in older adults...