Tracy Y Wang

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. doi request reprint Multivessel vs culprit-only percutaneous coronary intervention among patients 65 years or older with acute myocardial infarction
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 172:9-18. 2016
  2. doi request reprint Contemporary use of platelet function and pharmacogenomic testing among patients with acute myocardial infarction undergoing percutaneous coronary intervention in the United States
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC Electronic address
    Am Heart J 170:706-14. 2015
  3. doi request reprint Cluster-randomized clinical trial examining the impact of platelet function testing on practice: the treatment with adenosine diphosphate receptor inhibitors: longitudinal assessment of treatment patterns and events after acute coronary syndrome prospecti
    Tracy Y Wang
    From the Duke Clinical Research Institute, Department of Medicine, Duke University Medical Center, Durham, NC T Y W, E H, C N H, K J A, E D P Department of Medicine, Cedars Sinai Heart Institute, Los Angeles, CA T D H Lilly USA, LLC, Indianapolis, IN M B E, M E Z Department of Medicine, Saint Luke s Mid America Heart Institute, Kansas City, MO D J C Daiichi Sankyo, Inc, Parsippany, NJ B A B Department of Medicine, Geisinger Medical Center, Danville, PA P B B and Department of Medicine, University of Florida College of Medicine, Jacksonville, FL D J A
    Circ Cardiovasc Interv 8:e001712. 2015
  4. doi request reprint The quality of antiplatelet and anticoagulant medication administration among ST-segment elevation myocardial infarction patients transferred for primary percutaneous coronary intervention
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 167:833-9. 2014
  5. doi request reprint Cardiac biomarker measurement after elective percutaneous coronary interventions in older patients: insights from the National Cardiovascular Data Registry
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 166:927-34. 2013
  6. doi request reprint Platelet biology and response to antiplatelet therapy in women: implications for the development and use of antiplatelet pharmacotherapies for cardiovascular disease
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Am Coll Cardiol 59:891-900. 2012
  7. doi request reprint Percutaneous coronary intervention and drug-eluting stent use among patients ≥85 years of age in the United States
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, North Carolina 27705, USA
    J Am Coll Cardiol 59:105-12. 2012
  8. doi request reprint Door-to-balloon times for patients with ST-segment elevation myocardial infarction requiring interhospital transfer for primary percutaneous coronary intervention: a report from the national cardiovascular data registry
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 161:76-83.e1. 2011
  9. doi request reprint Association of door-in to door-out time with reperfusion delays and outcomes among patients transferred for primary percutaneous coronary intervention
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    JAMA 305:2540-7. 2011
  10. doi request reprint Upstream clopidogrel use and the efficacy and safety of early eptifibatide treatment in patients with acute coronary syndrome: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome (E
    Tracy Y Wang
    Duke Clinical Research Institute, 2400 Pratt St, Durham, NC 27705, USA
    Circulation 123:722-30. 2011

Collaborators

Detail Information

Publications87

  1. doi request reprint Multivessel vs culprit-only percutaneous coronary intervention among patients 65 years or older with acute myocardial infarction
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 172:9-18. 2016
    ..We sought to determine if nonculprit intervention during the index PCI is associated with better outcomes among older patients with acute MI and multivessel disease...
  2. doi request reprint Contemporary use of platelet function and pharmacogenomic testing among patients with acute myocardial infarction undergoing percutaneous coronary intervention in the United States
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC Electronic address
    Am Heart J 170:706-14. 2015
    ..Although platelet function and pharmacogenomic testing have been studied in clinical trials, their adoption into contemporary practice is unknown...
  3. doi request reprint Cluster-randomized clinical trial examining the impact of platelet function testing on practice: the treatment with adenosine diphosphate receptor inhibitors: longitudinal assessment of treatment patterns and events after acute coronary syndrome prospecti
    Tracy Y Wang
    From the Duke Clinical Research Institute, Department of Medicine, Duke University Medical Center, Durham, NC T Y W, E H, C N H, K J A, E D P Department of Medicine, Cedars Sinai Heart Institute, Los Angeles, CA T D H Lilly USA, LLC, Indianapolis, IN M B E, M E Z Department of Medicine, Saint Luke s Mid America Heart Institute, Kansas City, MO D J C Daiichi Sankyo, Inc, Parsippany, NJ B A B Department of Medicine, Geisinger Medical Center, Danville, PA P B B and Department of Medicine, University of Florida College of Medicine, Jacksonville, FL D J A
    Circ Cardiovasc Interv 8:e001712. 2015
    ..Little is known about how clinicians use platelet function testing to guide choice and dosing of adenosine diphosphate receptor inhibitor (ADPri) therapy in routine community practice...
  4. doi request reprint The quality of antiplatelet and anticoagulant medication administration among ST-segment elevation myocardial infarction patients transferred for primary percutaneous coronary intervention
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 167:833-9. 2014
    ....
  5. doi request reprint Cardiac biomarker measurement after elective percutaneous coronary interventions in older patients: insights from the National Cardiovascular Data Registry
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 166:927-34. 2013
    ..However, the long-term prognostic implications of biomarker measurement after elective PCI have not been well characterized in older patients...
  6. doi request reprint Platelet biology and response to antiplatelet therapy in women: implications for the development and use of antiplatelet pharmacotherapies for cardiovascular disease
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Am Coll Cardiol 59:891-900. 2012
    ..Knowledge gained about these mechanistic factors might inform the development of sex-specific antithrombotic treatment regimens that confer optimized safety and efficacy...
  7. doi request reprint Percutaneous coronary intervention and drug-eluting stent use among patients ≥85 years of age in the United States
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, North Carolina 27705, USA
    J Am Coll Cardiol 59:105-12. 2012
    ..This study assessed the comparative effectiveness of drug-eluting stents (DES) versus bare-metal stents (BMS) among patients ≥85 years of age...
  8. doi request reprint Door-to-balloon times for patients with ST-segment elevation myocardial infarction requiring interhospital transfer for primary percutaneous coronary intervention: a report from the national cardiovascular data registry
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 161:76-83.e1. 2011
    ..However, STEMI patients requiring interhospital transfer for primary PCI are often excluded from public performance assessments of this quality metric...
  9. doi request reprint Association of door-in to door-out time with reperfusion delays and outcomes among patients transferred for primary percutaneous coronary intervention
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    JAMA 305:2540-7. 2011
    ....
  10. doi request reprint Upstream clopidogrel use and the efficacy and safety of early eptifibatide treatment in patients with acute coronary syndrome: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome (E
    Tracy Y Wang
    Duke Clinical Research Institute, 2400 Pratt St, Durham, NC 27705, USA
    Circulation 123:722-30. 2011
    ..This analysis examines efficacy and safety of early eptifibatide in the setting of concurrent upstream clopidogrel use...
  11. doi request reprint The importance of consistent, high-quality acute myocardial infarction and heart failure care results from the American Heart Association's Get with the Guidelines Program
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Am Coll Cardiol 58:637-44. 2011
    ..This study examined the degree to which hospital performance for acute myocardial infarction (AMI) and heart failure (HF) care processes are correlated...
  12. doi request reprint The dissociation between door-to-balloon time improvement and improvements in other acute myocardial infarction care processes and patient outcomes
    Tracy Y Wang
    Department of Medicine, Duke Clinical Research Institute, Durham, North Carolina 27705, USA
    Arch Intern Med 169:1411-9. 2009
    ..However, DTB time is only one of several important AMI care processes. It is unclear whether quality efforts targeted to a single process will facilitate concomitant improvement in other quality measures and outcomes...
  13. doi request reprint Antithrombotic strategy in non-ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: insights from the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    JACC Cardiovasc Interv 3:669-77. 2010
    ..The aim of this study was to examine the use of and outcomes associated with antithrombotic strategies in patients with non-ST-segment elevation myocardial infarction (NSTEMI) who undergo percutaneous coronary intervention (PCI)...
  14. doi request reprint Incidence and prognostic significance of thrombocytopenia developed during acute coronary syndrome in contemporary clinical practice
    Tracy Y Wang
    Duke Clinical Research Institute, Terrace Level, Durham, NC 27705, USA
    Circulation 119:2454-62. 2009
    ..The incidence, severity, and prognostic significance of acquired thrombocytopenia during ACS in community practice have not been well defined...
  15. doi request reprint Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy
    Emil L Fosbol
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC The Heart Centre, University Hospital of Copenhagen, Rigshospitalet, Denmark Electronic address
    Am Heart J 166:864-70. 2013
    ..We sought to determine the risk of readmission for bleeding and major cardiac events in stented non-ST-segment elevation myocardial infarction (NSTEMI) atrial fibrillation (AF) patients...
  16. pmc Polyvascular disease and long-term cardiovascular outcomes in older patients with non-ST-segment-elevation myocardial infarction
    Sumeet Subherwal
    Duke University Medical Center, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 5:541-9. 2012
    ..The impact of polyvascular disease (peripheral arterial disease [PAD] and cerebrovascular disease [CVD]) on long-term cardiovascular outcomes among older patients with acute myocardial infarction has not been well studied...
  17. doi request reprint Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am J Med 125:897-905. 2012
    ..Atrial fibrillation guidelines recommend long-term use of warfarin according to a patient's predicted risk of stroke. After acute myocardial infarction, however, combining warfarin and antiplatelet medications poses challenges...
  18. doi request reprint In-hospital major bleeding during ST-elevation and non-ST-elevation myocardial infarction care: derivation and validation of a model from the ACTION Registry®-GWTG™
    Robin Mathews
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 107:1136-43. 2011
    ....
  19. doi request reprint Diagnostic blood loss from phlebotomy and hospital-acquired anemia during acute myocardial infarction
    Adam C Salisbury
    Department of Internal Medicine, Division of Cardiovascular Disease, Saint Luke s Mid America Heart and Vascular Institute, Kansas City, MO 64111, USA
    Arch Intern Med 171:1646-53. 2011
    ..The extent to which diagnostic phlebotomy, a modifiable process of care, contributes to HAA is unknown...
  20. doi request reprint Do patients treated at academic hospitals have better longitudinal outcomes after admission for non-ST-elevation myocardial infarction?
    Emily O'Brien
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC Electronic address
    Am Heart J 167:762-9. 2014
    ....
  21. doi request reprint Long-term outcomes after invasive management for older patients with non-ST-segment elevation myocardial infarction
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 6:323-32. 2013
    ....
  22. doi request reprint Red blood cell indices and development of hospital-acquired anemia during acute myocardial infarction
    Adam C Salisbury
    Saint Luke s Mid America Heart and Vascular Institute, Kansas City, Missouri, USA
    Am J Cardiol 109:1104-10. 2012
    ..34, 95% confidence interval 1.08 to 1.65) were independently more likely to develop moderate-severe HAA. In conclusion, increased RDW and low MCV were independent predictors of moderate-severe HAA...
  23. pmc Incidence, correlates, and outcomes of acute, hospital-acquired anemia in patients with acute myocardial infarction
    Adam C Salisbury
    Saint Luke s Mid America Heart Institute, Kansas City, MO, USA
    Circ Cardiovasc Qual Outcomes 3:337-46. 2010
    ..Anemia is common among patients hospitalized with acute myocardial infarction and is associated with poor outcomes. Less is known about the incidence, correlates, and prognostic implications of acute, hospital-acquired anemia (HAA)...
  24. doi request reprint Discharge antithrombotic strategies among patients with acute coronary syndrome previously on warfarin anticoagulation: physician practice in the CRUSADE registry
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 155:361-8. 2008
    ..The current management of ACS patients with a concomitant indication for warfarin anticoagulant therapy is a question of growing interest and clinical relevance...
  25. pmc Prognostic significance of bleeding location and severity among patients with acute coronary syndromes
    John P Vavalle
    Duke Clinical Research Institute, Durham, North Carolina 27705, USA
    JACC Cardiovasc Interv 6:709-17. 2013
    ..This study sought to determine if there is an association between bleed location and clinical outcomes in acute coronary syndromes (ACS) patients...
  26. pmc Hospital length of stay in patients with non-ST-segment elevation myocardial infarction
    John P Vavalle
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am J Med 125:1085-94. 2012
    ..Substantial heterogeneity in hospital length of stay exists among patients admitted with non-ST-segment elevation myocardial infarction. Furthermore, little is known about the factors that impact length of stay...
  27. doi request reprint Incidence of thrombocytopenia among patients receiving heparin venous thromboembolism prophylaxis
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am J Med 125:1214-21. 2012
    ..Heparin is commonly used for venous thromboembolism prophylaxis; however, the incidence of acquired thrombocytopenia in this setting has not been well described...
  28. doi request reprint Safety and effectiveness of antithrombotic strategies in older adult patients with atrial fibrillation and non-ST elevation myocardial infarction
    Emil L Fosbol
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 163:720-8. 2012
    ..We aimed to study the comparative safety and effectiveness of various antithrombotic treatment strategies among older adults with non-ST elevation myocardial infarction (NSTEMI) and atrial fibrillation (AF)...
  29. doi request reprint Hospital-acquired anemia and in-hospital mortality in patients with acute myocardial infarction
    Adam C Salisbury
    Saint Luke s Mid Asmerica Heart and Vascular Institute, Kansas City, MO 64111, USA
    Am Heart J 162:300-309.e3. 2011
    ..The relationship between HAA and adverse in-hospital outcomes may be particularly relevant to hospitals' efforts to implement prevention programs, but the association between HAA and in-hospital mortality is unclear...
  30. doi request reprint Antiplatelet therapy use after discharge among acute myocardial infarction patients with in-hospital bleeding
    Tracy Y Wang
    Duke Clinical Research Institute, 2400 Pratt St, Room 0311, Terrace Level, Durham, NC 27705, USA
    Circulation 118:2139-45. 2008
    ..Although the mechanism underlying this association is unclear, a potential explanation is that withholding antiplatelet therapies long beyond resolution of the bleeding event may contribute to recurrent events...
  31. doi request reprint Comparison of percutaneous coronary intervention for previously treated versus de novo culprit lesions in acute myocardial infarction patients: insights from the National Cardiovascular Data Registry
    Chee Tang Chin
    Duke Clinical Research Institute, Durham, NC National Heart Centre Singapore, Singapore Electronic address
    Am Heart J 167:393-400.e1. 2014
    ..Outcomes may differ depending on whether PCI is performed on a previously treated or de novo culprit lesion...
  32. doi request reprint Hospital patterns of medical management strategy use for patients with non-ST-elevation myocardial infarction and 3-vessel or left main coronary artery disease
    Ralf E Harskamp
    Duke Clinical Research Institute, Durham, NC Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am Heart J 167:355-362.e3. 2014
    ....
  33. doi request reprint Incorporation of bleeding as an element of the composite end point in clinical trials of antithrombotic therapies in patients with non-ST-segment elevation acute coronary syndrome: validity, pitfalls, and future approaches
    Sumeet Subherwal
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 165:644-54, 654.e1. 2013
    ..We describe alternative statistical approaches for concurrent assessment of the safety and efficacy of antithrombotic therapies used to treat patients with NSTE ACS...
  34. doi request reprint Hypercholesterolemia paradox in relation to mortality in acute coronary syndrome
    Tracy Y Wang
    Division of Cardiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    Clin Cardiol 32:E22-8. 2009
    ..Hypercholesterolemia is a risk factor for coronary artery disease, yet is associated with lower risk of adverse outcomes in patients with acute coronary syndromes (ACS)...
  35. pmc The association of in-hospital major bleeding with short-, intermediate-, and long-term mortality among older patients with non-ST-segment elevation myocardial infarction
    Renato D Lopes
    Duke Clinical Research Institute, Box 3850, 2400 Pratt Street, Room 0311, Terrace Level, Durham, NC 27705, USA
    Eur Heart J 33:2044-53. 2012
    ..Their association with long-term outcomes is less clear. This study examines mortality associated with in-hospital bleeding during NSTEMI over time intervals starting from hospital discharge and extending past 3 years...
  36. doi request reprint Implications and reasons for the lack of use of reperfusion therapy in patients with ST-segment elevation myocardial infarction: findings from the CRUSADE initiative
    Shahyar Michael Gharacholou
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 159:757-63. 2010
    ..However, many STEMI patients in contemporary practice still do not receive any form of reperfusion therapy...
  37. doi request reprint Risk adjustment for in-hospital mortality of contemporary patients with acute myocardial infarction: the acute coronary treatment and intervention outcomes network (ACTION) registry-get with the guidelines (GWTG) acute myocardial infarction mortality mode
    Chee Tang Chin
    Duke Clinical Research Institute, Durham, NC National Heart Centre Singapore, Singapore
    Am Heart J 161:113-122.e2. 2011
    ..We developed and validated a model to predict the risk of in-hospital mortality for contemporary patients with acute MI treated in routine clinical practice...
  38. doi request reprint Admission international normalized ratio levels, early treatment strategies, and major bleeding risk among non-ST-segment-elevation myocardial infarction patients on home warfarin therapy: insights from the National Cardiovascular Data Registry
    Sumeet Subherwal
    Duke University, 2500 Pratt St, Durham, NC 27715, USA
    Circulation 125:1414-23. 2012
    ..Yet, little is known about contemporary treatment patterns and bleeding risks in this population...
  39. doi request reprint Differences in the profile, treatment, and prognosis of patients with cardiogenic shock by myocardial infarction classification: A report from NCDR
    Monique L Anderson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC
    Circ Cardiovasc Qual Outcomes 6:708-15. 2013
    ..We sought to characterize differences in patient features, treatments, and outcomes of cardiogenic shock by MI classification: ST-segment-elevation MI (STEMI) versus non-ST-segment elevation MI (NSTEMI)...
  40. doi request reprint Impact of home warfarin use on treatment patterns and bleeding complications for patients with non-ST-segment elevation acute coronary syndromes: observations from the CRUSADE quality improvement initiative
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt Street, Room 0311, Terrace Level, Durham, NC 27705, USA
    Eur Heart J 29:1103-9. 2008
    ..To examine treatment patterns and outcomes of patients with non-ST-segment elevation acute coronary syndrome (NSTE ACS) receiving long-term warfarin anticoagulation...
  41. doi request reprint Trends in outcomes among older patients with non-ST-segment elevation myocardial infarction
    Chee Tang Chin
    Duke Clinical Research Institute, Durham, NC National Heart Centre Singapore, Singapore Electronic address
    Am Heart J 167:36-42.e1. 2014
    ..The objective of this study is to assess trends in evidence-based therapy use and short- and long-term mortality over time among older patients with non-ST-segment elevation myocardial infarction (NSTEMI)...
  42. doi request reprint Use of early clopidogrel by reperfusion strategy among patients presenting with ST-segment elevation myocardial infarction
    Chiara Melloni
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt St, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 4:603-9. 2011
    ..The 2007 update of the ACC/AHA guidelines for STEMI patients recommended addition of clopidogrel to aspirin regardless of reperfusion strategy, with a bolus dose in patients <75 years of age...
  43. doi request reprint Risk of heart failure complication during hospitalization for acute myocardial infarction in a contemporary population: insights from the National Cardiovascular Data ACTION Registry
    Ravi V Shah
    Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Circ Heart Fail 5:693-702. 2012
    ..Patients with acute myocardial infarction (MI) complicated by heart failure (HF) are subject to higher mortality during the index hospitalization. Early risk prediction and intervention may help prevent HF-related morbidity and mortality...
  44. doi request reprint Long-term outcomes among older patients with non-ST-segment elevation myocardial infarction complicated by cardiogenic shock
    Akshay Bagai
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 166:298-305. 2013
    ....
  45. doi request reprint Limitations of using cardiac catheterization rates to assess the quality of care for patients with non-ST-segment elevation myocardial infarction
    Sergio Leonardi
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 164:502-8. 2012
    ..However, the frequency of CCC reporting has not been delineated, and the relationship of CCC reporting to hospital-level guidelines adherence for NSTEMI has not been investigated...
  46. doi request reprint Comparison of the prognostic value of peak creatine kinase-MB and troponin levels among patients with acute myocardial infarction: a report from the Acute Coronary Treatment and Intervention Outcomes Network Registry-get with the guidelines
    Chee Tang Chin
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Clin Cardiol 35:424-9. 2012
    ....
  47. doi request reprint Trends in the prevalence and outcomes of radial and femoral approaches to percutaneous coronary intervention: a report from the National Cardiovascular Data Registry
    Sunil V Rao
    The Duke Clinical Research Institute, Durham, North Carolina, USA
    JACC Cardiovasc Interv 1:379-86. 2008
    ..Our goal was to compare trends in the prevalence and outcomes of the radial and femoral approaches to percutaneous coronary intervention (PCI) in contemporary clinical practice...
  48. doi request reprint Excess heparin dosing among fibrinolytic-treated patients with ST-segment elevation myocardial infarction
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    Am J Med 121:805-10. 2008
    ....
  49. doi request reprint Transfusion practice and outcomes in non-ST-segment elevation acute coronary syndromes
    Karen P Alexander
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Am Heart J 155:1047-53. 2008
    ..To describe the association between transfusion and outcomes as a function of nadir hematocrit (HCT) in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS)...
  50. doi request reprint Predicting long-term mortality in older patients after non-ST-segment elevation myocardial infarction: the CRUSADE long-term mortality model and risk score
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 162:875-883.e1. 2011
    ..We sought to develop a long-term mortality risk prediction model and a simplified risk score for use in older patients with non-ST-segment elevation myocardial infarction (NSTEMI)...
  51. doi request reprint Incidence and outcomes of no-reflow phenomenon during percutaneous coronary intervention among patients with acute myocardial infarction
    Robert W Harrison
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 111:178-84. 2013
    ..Upfront strategies to reduce the incidence of no-reflow could be considered for high-risk patients to improve outcomes...
  52. doi request reprint Early Medication Nonadherence After Acute Myocardial Infarction: Insights into Actionable Opportunities From the TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS)
    Robin Mathews
    From the Duke Clinical Research Institute, Durham, NC R M, E D P, E H, T Y W National Health Centre Singapore, Singapore, Singapore C T C Lilly, USA, LLC, Indianapolis M B E, M Z Ahmanson UCLA Cardiomyopathy Center, University of California Los Angeles G C F and Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital T D H
    Circ Cardiovasc Qual Outcomes 8:347-56. 2015
    ..We sought to better understand the modifiable factors contributing to early nonadherence of evidence-based medications after acute MI...
  53. doi request reprint Unplanned Inpatient and Observation Rehospitalizations After Acute Myocardial Infarction: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (T
    Connie N Hess
    From Duke Clinical Research Institute, Durham, NC C N H, T Y W, L A M, E P P Division of Cardiology, University of Colorado School of Medicine, Aurora, CO J C M Lilly USA LLC, Indianapolis, IN M B E, M E Z Cedars Sinai Heart Institute, Los Angeles, CA T D H and Ahmanson UCLA Cardiomyopathy Center, University of California Los Angeles G C F
    Circulation 133:493-501. 2016
    ..However, from a patient's perspective, any unplanned inpatient or observation rehospitalization after acute myocardial infarction represents a significant event; these unplanned rehospitalizations have not been well characterized...
  54. doi request reprint Association of Discharge Aspirin Dose With Outcomes After Acute Myocardial Infarction: Insights From the Treatment with ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) Study
    Ying Xian
    From Duke Clinical Research Institute, Duke University Medical Center, Durham, NC Y X, T Y W, L A M, E D P Lilly USA LLC, Indianapolis, IN M B E, M E Z Cedars Sinai Heart Institute, Los Angeles, CA T D H Washington University School of Medicine, St Louis, MO R G B Daiichi Sankyo Inc, Parsippany, NJ B A B and UCLA Medical Center, Los Angeles, CA G C F
    Circulation 132:174-81. 2015
    ..Aspirin is the most widely used antiplatelet drug postmyocardial infarction, yet its optimal maintenance dose after percutaneous coronary intervention with stenting remains uncertain...
  55. doi request reprint Use and Outcomes of Triple Therapy Among Older Patients With Acute Myocardial Infarction and Atrial Fibrillation
    Connie N Hess
    Duke Clinical Research Institute, Duke University, Durham, North Carolina Electronic address
    J Am Coll Cardiol 66:616-27. 2015
    ..Antithrombotic therapy for acute myocardial infarction (MI) with atrial fibrillation (AF) among higher risk older patients treated with percutaneous coronary intervention (PCI) remains unclear...
  56. pmc Modifiable factors associated with failure to attain low-density lipoprotein cholesterol goal at 6 months after acute myocardial infarction
    Seth S Martin
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am Heart J 165:26-33.e3. 2013
    ..We sought to illuminate patient and provider characteristics associated with LDL-C goal nonattainment after AMI...
  57. doi request reprint Incidence, distribution, and prognostic impact of occluded culprit arteries among patients with non-ST-elevation acute coronary syndromes undergoing diagnostic angiography
    Tracy Y Wang
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 157:716-23. 2009
    ....
  58. doi request reprint Use of emergency medical service transport among patients with ST-segment-elevation myocardial infarction: findings from the National Cardiovascular Data Registry Acute Coronary Treatment Intervention Outcomes Network Registry-Get With The Guidelines
    Robin Mathews
    Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt St, Durham, NC 27705, USA
    Circulation 124:154-63. 2011
    ....
  59. doi request reprint Blood transfusion during acute myocardial infarction: association with mortality and variability across hospitals
    Adam C Salisbury
    Department of Cardiology, Saint Luke s Mid America Heart Institute, Kansas City, Missouri University of Missouri Kansas City School of Medicine, Kansas City, Missouri Electronic address
    J Am Coll Cardiol 64:811-9. 2014
    ..Blood transfusion is controversial for anemic patients with acute myocardial infarction (AMI), with some previous studies reporting increased risk of transfusion-associated mortality...
  60. doi request reprint Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC Electronic address
    Am J Med 128:582-90. 2015
    ..We aimed to evaluate mortality and cause-specific rehospitalization rates in this growing population of older adults with ischemic heart disease...
  61. doi request reprint Targeted versus standard feedback: results from a randomized quality improvement trial
    Barbara L Lytle
    Duke Clinical Research Institute, Durham, NC
    Am Heart J 169:132-41.e2. 2015
    ..Quality improvement is central to improving the care of patients with cardiovascular disease; however, the optimum type of data feedback to support such efforts is unknown...
  62. doi request reprint Spousal depression, anxiety, and suicide after myocardial infarction
    Emil L Fosbøl
    Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt Street, Room 7461, Terrace Level, Durham, NC 27705, USA
    Eur Heart J 34:649-56. 2013
    ..Death of a spouse from acute myocardial infarction (AMI) presents hardship, yet few studies have investigated the psychological consequences of fatal and non-fatal AMI on spouses...
  63. pmc Randomized trial of targeted performance feedback to facilitate quality improvement in acute myocardial infarction care
    Karen P Alexander
    Duke Clinical Research Institute, Durham, NC 27710, USA
    Circ Cardiovasc Qual Outcomes 4:129-35. 2011
    ..Efforts to improve quality of care for patients with acute myocardial infarction (AMI) are a national priority. To date, there have been few studies that have prospectively evaluated hospital quality improvement (QI) interventions...
  64. doi request reprint Representation of women in randomized clinical trials of cardiovascular disease prevention
    Chiara Melloni
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 3:135-42. 2010
    ....
  65. doi request reprint Differences in short-term versus long-term outcomes of older black versus white patients with myocardial infarction: findings from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of America
    Robin Mathews
    From the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC R M, A Y C, L T, T Y W, K L T, M T R, E D P and National Heart Centre Singapore, Singapore C T C
    Circulation 130:659-67. 2014
    ..Blacks are less likely than whites to receive coronary revascularization and evidence-based therapies after acute myocardial infarction, yet the impact of these differences on long-term outcomes is unknown...
  66. ncbi request reprint Comparison of baseline characteristics, treatment patterns, and in-hospital outcomes of Asian versus non-Asian white Americans with non-ST-segment elevation acute coronary syndromes from the CRUSADE quality improvement initiative
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 100:391-6. 2007
    ..Further investigation is needed to explore the potential for ethnic variability in antithrombotic susceptibility...
  67. doi request reprint G-protein-coupled receptors as signaling targets for antiplatelet therapy
    Susan S Smyth
    Veterans Affairs Medical Center, Department of Medicine, Physiology, and Pharmacology, University of Kentucky, Lexington, KY, USA
    Arterioscler Thromb Vasc Biol 29:449-57. 2009
    ..The identification and development of new agents directed against specific platelet signaling pathways may offer an advantage in preventing thrombotic events while minimizing bleeding risk...
  68. pmc Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development
    Marlene S Williams
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Arterioscler Thromb Vasc Biol 30:2372-84. 2010
    ....
  69. doi request reprint Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction
    Sean D Pokorney
    Division of Cardiology, Duke University Medical Center, Durham, North Carolina2Duke Clinical Research Institute, Durham, North Carolina
    JAMA 313:2433-40. 2015
    ..Implantable cardioverter-defibrillators (ICDs) are not recommended within 40 days of myocardial infarction (MI); thus, ICD implantation might not be considered during the post-MI care transition...
  70. pmc Early clopidogrel versus prasugrel use among contemporary STEMI and NSTEMI patients in the US: insights from the National Cardiovascular Data Registry
    Matthew W Sherwood
    Division of Cardiovascular Medicine, Duke University Medical Center, Duke Clinical Research Institute, Durham, NC
    J Am Heart Assoc 3:e000849. 2014
    ..Novel agents in this class are now available in the US. We studied the introduction of prasugrel into contemporary MI practice to understand the appropriateness of its use and assess for changes in antiplatelet management practices...
  71. doi request reprint Dissociation between hospital performance of the smoking cessation counseling quality metric and cessation outcomes after myocardial infarction
    Gordon R Reeves
    Department of Internal Medicine, Duke Clinical Research Institute, Durham, NC 27705, USA
    Arch Intern Med 168:2111-7. 2008
    ..Yet, the association between hospitals' performance of this quality measure and subsequent tobacco cessation rates has not been established...
  72. doi request reprint Statin Treatment by Low-Density Lipoprotein Cholesterol Levels in Patients With Non-ST-Segment Elevation Myocardial Infarction/Unstable Angina Pectoris (from the CRUSADE Registry)
    Emily C O'Brien
    Department of Medicine, Duke Clinical Research Institute, Durham, North Carolina Electronic address
    Am J Cardiol 115:1655-60. 2015
    ..In conclusion, >1/3 of patients with NSTEMI/UAP had an LDL-C level <100. Those with low LDL-C were older, had more co-morbidities, and were less likely to be prescribed a statin at discharge than those with higher LDL-C. ..
  73. doi request reprint Persistence with secondary prevention medications after acute myocardial infarction: Insights from the TRANSLATE-ACS study
    Robin Mathews
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 170:62-9. 2015
    ..Persistent use of secondary prevention therapies after acute myocardial infarction (MI) is critical to optimizing long-term outcomes...
  74. doi request reprint Fibrinolysis use among patients requiring interhospital transfer for ST-segment elevation myocardial infarction care: a report from the US National Cardiovascular Data Registry
    Amit N Vora
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
    JAMA Intern Med 175:207-15. 2015
    ..Among patients with STEMI who require interhospital transfer, it is unclear how reperfusion strategy selection and outcomes vary with interhospital drive times...
  75. doi request reprint In-hospital switching between clopidogrel and prasugrel among patients with acute myocardial infarction treated with percutaneous coronary intervention: insights into contemporary practice from the national cardiovascular data registry
    Akshay Bagai
    From the Terrence Donnelly Heart Center, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada A B, A N C Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT Y W, J P C, R L M Duke Clinical Research Institute, Durham, NC T Y W, E D P, C B G, M T R, K P A Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor H S G New York University School of Medicine B S NorthShore University Health System, Evanston, IL J F S and Brigham and Women s Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA D L B
    Circ Cardiovasc Interv 7:585-93. 2014
    ....
  76. doi request reprint Evaluation of a new heparin agent in percutaneous coronary intervention: results of the phase 2 evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) Trial
    Sunil V Rao
    Duke Clinical Research Institute, Durham, NC, USA
    Circulation 121:1713-21. 2010
    ..We performed a phase 2 randomized trial to evaluate the safety and feasibility of M118 in the setting of elective percutaneous coronary intervention...
  77. pmc Sex-based differences in outcomes after percutaneous coronary intervention for acute myocardial infarction: a report from TRANSLATE-ACS
    Connie N Hess
    Duke Clinical Research Institute, Durham, NC
    J Am Heart Assoc 3:e000523. 2014
    ..Data regarding sex-based outcomes after percutaneous coronary intervention (PCI) for myocardial infarction are mixed. We sought to examine whether sex differences in outcomes exist in contemporary practice...
  78. doi request reprint Percutaneous coronary intervention in the elderly
    Tracy Y Wang
    Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC 27705, USA
    Nat Rev Cardiol 8:79-90. 2011
    ....
  79. pmc Perioperative management of patients on clopidogrel (Plavix) undergoing major lung resection
    Duykhanh P Ceppa
    Department of Surgery, Division of Thoracic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 92:1971-6. 2011
    ..We reviewed our experience with patients treated with clopidogrel perioperatively to examine outcomes, including results of a new strategy for high-risk patients...
  80. doi request reprint Hematologic diseases: from within the heart
    Weixian Xu
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, United States
    Rev Esp Cardiol (Engl Ed) 64:606-13. 2011
    ..Venous thromboembolism is employed in our discussion as a clinical template. We also provide practical steps and guidance for diagnostic testing and management in routine clinical practice. ..
  81. doi request reprint [Hematologic diseases: from within the heart]
    Weixian Xu
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
    Rev Esp Cardiol 64:606-13. 2011
    ..We also provide practical steps and guidance for diagnostic testing and management in routine clinical practice. Full English text available from: www.revespcardiol.org...
  82. doi request reprint Closing the gap: treating hypertension in women
    Zainab Samad
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
    Cardiol Rev 16:305-13. 2008
    ..This review will focus on sex-specific factors that contribute to hypertension in women, and current patterns and efficacy of treatment. In addition, we will highlight evidence-based options for antihypertensive treatment in women...
  83. ncbi request reprint Anemia in patients undergoing percutaneous coronary intervention: current issues and future directions
    Tracy Y Wang
    Duke University Medical Center, Durham VA Medical Center, Durham, North Carolina, USA
    Am J Cardiovasc Drugs 7:225-33. 2007
    ..In addition, we discuss alternative options for the management of anemia, such as the use of erythropoietin, aqueous oxygen, and hemoglobin-based oxygen carriers...
  84. ncbi request reprint Markers of cardiac ischemia and inflammation
    Tracy Y Wang
    Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA
    Cardiol Clin 23:491-501, vi. 2005
    ....
  85. ncbi request reprint The Cobalt chromium STent with Antiproliferative for Restenosis II (COSTAR II) trial study design: advancing the active-control evaluation of second-generation drug-eluting stents
    Tracy Y Wang
    Duke Clinical Research Institute, Duke University, Durham, NC, USA
    Am Heart J 153:743-8. 2007
    ..The results of COSTAR II will provide information about a novel coronary stent device as well as unique data regarding both control and test DES use in more complex "real-world" patients...
  86. doi request reprint The feasibility and accuracy of evaluating lipid management performance metrics using an electronic health record
    Christopher P Danford
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 166:701-8. 2013
    ....
  87. ncbi request reprint How Should Patients Requiring Dual Antiplatelet Therapy be Managed When Undergoing Elective Endoscopic Gastrointestinal Procedures?
    Matthew W Sherwood
    Division of Cardiology, Duke University School of Medicine, DUMC 3850, Durham, NC, 27710, USA
    Curr Treat Options Cardiovasc Med 13:46-56. 2011
    ..A loading dose of the former should be considered among patients at risk for thrombosis. Continue platelet-directed therapy in patients undergoing elective endoscopy procedures associated with a low risk for bleeding...