Research Topics
| Larry A TuplerSummaryAffiliation: Duke University Medical Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Detecting traumatic brain injury among veterans of Operations Enduring and Iraqi FreedomGeorge L Jackson
Center for Health Services Research in Primary Care, Durham Veteran Affairs Medical Center, 508 Fulton Street, Durham, NC 27705, USA
N C Med J 69:43-7. 2008
Predicting memory decline in normal elderly: genetics, MRI, and cognitive reserveLarry A Tupler
Department of Psychiatry and Behavioral Sciences, Box 3018, Duke University Medical Center, Durham, NC 27710, USA
Neurobiol Aging 28:1644-56. 2007..Age and sex did not enter into the model. We conclude that APOE-epsilon4 predicts longitudinal memory decline in healthy controls and that MRI morphometry of hippocampus adds slightly to predictive value...
Anatomic location and laterality of MRI signal hyperintensities in late-life depressionLarry A Tupler
Department of Psychiatry and Behavioral Sciences, Box 3018, Duke University Medical Center, Durham, NC 27710, USA
J Psychosom Res 53:665-76. 2002..We sought to examine the severity and location of white- and gray-matter lesions in a group of elderly depressives and nondepressed control subjects...
Exploration of the resilience construct in posttraumatic stress disorder severity and functional correlates in military combat veterans who have served since September 11, 2001Kimberly T Green
VISN 6 MIRECC, 508 Fulton Street, Durham, NC 27705, USA
J Clin Psychiatry 71:823-30. 2010..This study evaluated the relationship between resilience and psychological functioning in military veterans deployed to a region of military conflict in support of Operation Enduring Freedom or Operation Iraqi Freedom...
H.M.'s personal crossword puzzles: understanding memory and languageBrian G Skotko
Duke University, Durham, NC, USA
Memory 16:89-96. 2008..M.'s lexical word-retrieval skills remain fluid despite his profound anterograde amnesia. Once acquired, the maintenance of written language comprehension and production does not seem to require intact medial temporal lobe structures...
Factorial invariance of posttraumatic stress disorder symptoms across three veteran samplesScott D McDonald
VA Mid Atlantic Region Mental Illness Research, Education and Clinical Center MIRECC, Durham VA Medical Center, Durham, NC 27705, USA
J Trauma Stress 21:309-17. 2008..Results supported factor invariance across the three veteran cohorts, suggesting that cross-group comparisons are interpretable. Implications and applications for DSM-IV nosology and the validity of symptom measures are discussed...
Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001Jason D Kilts
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27705, USA
Pain Med 11:1469-76. 2010..We thus hypothesized that endogenous allopregnanolone and other neurosteroid levels may be negatively correlated with self-reported pain symptoms in humans...
Segmented hippocampal volume in children and adolescents with posttraumatic stress disorderLarry A Tupler
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Biol Psychiatry 59:523-9. 2006..CONCLUSIONS: Future longitudinal studies with trauma control subjects and neuropsychological measures are indicated to further elucidate the relationship between hippocampus and behavioral abnormalities in young PTSD subjects...
Puzzling thoughts for H. M.: can new semantic information be anchored to old semantic memories?Brian G Skotko
Department of Biological Anthropology and Anatomy, Duke University, Durham, NC, USA
Neuropsychology 18:756-69. 2004..From the results, the authors concluded that H. M. can acquire new semantic knowledge, at least temporarily, when he can anchor it to mental representations established preoperatively...
MR signal intensity of gray matter/white matter contrast and intracranial fat: effects of age and sexDennis M Kim
School of Medicine, Duke University Medical Center, 27710, Durham, NC, USA
Psychiatry Res 114:149-61. 2002..Implications for brain morphometry, the use of fat as a reference standard, and other issues in neuroimaging are discussed...
Focal and lateralized subcortical abnormalities in unipolar major depressive disorder: an automated multivoxel proton magnetic resonance spectroscopy studyMeena Vythilingam
Mood and Anxiety Disorders Program, National Institute of Mental Health, NIH, Bethesda, Maryland 20892, USA
Biol Psychiatry 54:744-50. 2003..Our results are consistent with prior magnetic resonance imaging, positron emission tomography, and postmortem reports of focal and lateralized abnormalities of the basal ganglia in MDD...
