Laura Svetkey

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. doi request reprint Predictors of long-term weight loss in adults with modest initial weight loss, by sex and race
    Laura P Svetkey
    Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, USA
    Obesity (Silver Spring) 20:1820-8. 2012
  2. pmc Hypertension Improvement Project (HIP): study protocol and implementation challenges
    Rowena J Dolor
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Trials 10:13. 2009
  3. ncbi request reprint Effect of lifestyle modifications on blood pressure by race, sex, hypertension status, and age
    L P Svetkey
    Duke Hypertension Center and the Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    J Hum Hypertens 19:21-31. 2005
  4. ncbi request reprint Effect of the dietary approaches to stop hypertension diet and reduced sodium intake on blood pressure control
    Laura P Svetkey
    Duke Hypertension Center, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Hypertens (Greenwich) 6:373-81. 2004
  5. ncbi request reprint Management of prehypertension
    Laura P Svetkey
    Duke Hypertension Center and the Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    Hypertension 45:1056-61. 2005
  6. ncbi request reprint Premier: a clinical trial of comprehensive lifestyle modification for blood pressure control: rationale, design and baseline characteristics
    Laura P Svetkey
    Duke Hypertension Center and Sarah W Stedman Center for Nutritional Studies, Duke University Medical Center, Durham, NC, USA
    Ann Epidemiol 13:462-71. 2003
  7. doi request reprint Comparison of strategies for sustaining weight loss: the weight loss maintenance randomized controlled trial
    Laura P Svetkey
    Division of Nephrology, Department of Medicine, Duke Hypertension Center and Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    JAMA 299:1139-48. 2008
  8. pmc Hypertension improvement project: randomized trial of quality improvement for physicians and lifestyle modification for patients
    Laura P Svetkey
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Hypertension 54:1226-33. 2009
  9. pmc Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system
    Laura P Svetkey
    Duke University Medical Center, Durham, North Carolina, USA
    Am J Hypertens 24:209-17. 2011
  10. ncbi request reprint Angiotensinogen genotype and blood pressure response in the Dietary Approaches to Stop Hypertension (DASH) study
    L P Svetkey
    Duke Hypertension Center and Sarah W Stedman Center for Nutritional Studies, Duke University Medical Center, Durham, North Carolina 27705, USA
    J Hypertens 19:1949-56. 2001

Research Grants

  1. PREMIER Maintenance Trial(MAINTENANCE)
    Laura Svetkey; Fiscal Year: 2007
  2. WEIGHT LOSS MAINTENANCE TRIAL
    Laura Svetkey; Fiscal Year: 2007
  3. Hypertension Improvement Project (HIP)
    Laura Svetkey; Fiscal Year: 2007
  4. The DASH-Sodium Trial: Genetic Determinants of Response
    Laura Svetkey; Fiscal Year: 2004
  5. PREMIER--LIFESTYLE INTERVENTION BLOOD PRESSURE CONTROL
    Laura Svetkey; Fiscal Year: 2002
  6. Hypertension Improvement Project(HIP)
    Laura Svetkey; Fiscal Year: 2007

Detail Information

Publications53

  1. doi request reprint Predictors of long-term weight loss in adults with modest initial weight loss, by sex and race
    Laura P Svetkey
    Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, USA
    Obesity (Silver Spring) 20:1820-8. 2012
    ..Few other variables other than initial weight loss and dietary pattern were predictive. Future research should identify additional modifiable influences on long-term maintenance after a modest weight loss...
  2. pmc Hypertension Improvement Project (HIP): study protocol and implementation challenges
    Rowena J Dolor
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Trials 10:13. 2009
    ..The chronic care model suggests that blood pressure control can be achieved by improving how patients and physicians address patient self-care...
  3. ncbi request reprint Effect of lifestyle modifications on blood pressure by race, sex, hypertension status, and age
    L P Svetkey
    Duke Hypertension Center and the Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    J Hum Hypertens 19:21-31. 2005
    ..In conclusion, diverse groups of people can adopt multiple lifestyle changes that can lead to improved BP control and reduced CVD risk...
  4. ncbi request reprint Effect of the dietary approaches to stop hypertension diet and reduced sodium intake on blood pressure control
    Laura P Svetkey
    Duke Hypertension Center, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Hypertens (Greenwich) 6:373-81. 2004
    ..BP became normal or optimal in 71% of persons consuming the control/lower sodium diet and 77% of persons consuming the DASH/lower sodium diet. Both the DASH diet and reduced sodium intake improved BP control...
  5. ncbi request reprint Management of prehypertension
    Laura P Svetkey
    Duke Hypertension Center and the Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    Hypertension 45:1056-61. 2005
  6. ncbi request reprint Premier: a clinical trial of comprehensive lifestyle modification for blood pressure control: rationale, design and baseline characteristics
    Laura P Svetkey
    Duke Hypertension Center and Sarah W Stedman Center for Nutritional Studies, Duke University Medical Center, Durham, NC, USA
    Ann Epidemiol 13:462-71. 2003
    ..To describe PREMIER, a randomized trial to determine the effects of multi-component lifestyle interventions on blood pressure (BP)...
  7. doi request reprint Comparison of strategies for sustaining weight loss: the weight loss maintenance randomized controlled trial
    Laura P Svetkey
    Division of Nephrology, Department of Medicine, Duke Hypertension Center and Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    JAMA 299:1139-48. 2008
    ..Behavioral weight loss interventions achieve short-term success, but re-gain is common...
  8. pmc Hypertension improvement project: randomized trial of quality improvement for physicians and lifestyle modification for patients
    Laura P Svetkey
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Hypertension 54:1226-33. 2009
    ..Differences between treatment groups did not persist at 18 months. Combined physician and patient interventions lowers blood pressure; future research should focus on enhancing effectiveness and sustainability of these interventions...
  9. pmc Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system
    Laura P Svetkey
    Duke University Medical Center, Durham, North Carolina, USA
    Am J Hypertens 24:209-17. 2011
    ..The purpose of this study was to identify genes that modulate BP response to dietary interventions...
  10. ncbi request reprint Angiotensinogen genotype and blood pressure response in the Dietary Approaches to Stop Hypertension (DASH) study
    L P Svetkey
    Duke Hypertension Center and Sarah W Stedman Center for Nutritional Studies, Duke University Medical Center, Durham, North Carolina 27705, USA
    J Hypertens 19:1949-56. 2001
    ..The angiotensin converting enzyme (ACE) gene was also tested...
  11. ncbi request reprint Preliminary evidence of linkage of salt sensitivity in black Americans at the beta 2-adrenergic receptor locus
    L P Svetkey
    Duke University Medical Center, Durham, NC 27710, USA
    Hypertension 29:918-22. 1997
    ..006). Evidence for linkage was significant at the .05 level after adjustment for the number of phenotypic traits examined...
  12. pmc Take Control of Your Blood Pressure (TCYB) study: a multifactorial tailored behavioral and educational intervention for achieving blood pressure control
    Hayden B Bosworth
    Center for Health Services Research in Primary Care, Durham VAMC, United States
    Patient Educ Couns 70:338-47. 2008
    ..Evaluating a randomized controlled trial involving a tailored behavioral intervention conducted to improve blood pressure control...
  13. ncbi request reprint Heritability of salt sensitivity in black Americans
    L P Svetkey
    Duke University Medical Center, Durham, NC, USA
    Hypertension 28:854-8. 1996
    ..Corresponding heritability estimates were 0.26 to 0.84, 0.26 to 0.74, and 0.004 to 0.24, respectively. These data strongly suggest a heritable component of salt sensitivity...
  14. ncbi request reprint Protease inhibitors are associated with a slowed progression of HIV-related renal diseases
    L A Szczech
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Clin Nephrol 57:336-41. 2002
    ..This study describes the clinical course of HIV-related renal diseases and the effect of protease inhibitors on their progression...
  15. pmc Microalbuminuria predicts overt proteinuria among patients with HIV infection
    L A Szczech
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    HIV Med 11:419-26. 2010
    ..This study examines the association between microalbuminuria and the development of proteinuria among HIV-infected persons...
  16. ncbi request reprint Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group
    F M Sacks
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 344:3-10. 2001
    ....
  17. ncbi request reprint Effects of gender and ethnic group on blood pressure control in the elderly
    L P Svetkey
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Am J Hypertens 9:529-35. 1996
    ..The choice of antihypertensive agent may also be important. Further investigation is needed into the mechanisms accounting for the observed sex and race differences...
  18. ncbi request reprint DASH (Dietary Approaches to Stop Hypertension) diet is effective treatment for stage 1 isolated systolic hypertension
    T J Moore
    Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA
    Hypertension 38:155-8. 2001
    ..Our results indicate that the DASH diet, which is rich in fruits, vegetables, and low-fat dairy foods, is effective as first-line therapy in stage 1 ISH...
  19. ncbi request reprint The impact of angiotensin II receptor blockade and the DASH diet on markers of endogenous fibrinolysis
    T P Erlinger
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Hum Hypertens 16:391-7. 2002
    ..In contrast, the DASH diet had no significant effect on markers of fibrinolysis in whites or African-Americans...
  20. ncbi request reprint Effect of dietary patterns on ambulatory blood pressure : results from the Dietary Approaches to Stop Hypertension (DASH) Trial. DASH Collaborative Research Group
    T J Moore
    Department of Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Hypertension 34:472-7. 1999
    ..These results demonstrate that the DASH combination diet provides significant round-the-clock reduction in BP, especially in hypertensive participants...
  21. ncbi request reprint Renovascular hypertension in blacks
    O E Emovon
    Department of Medicine and Radiology, Duke University Medical Center, Durham, North Carolina, USA
    Am J Hypertens 9:18-23. 1996
    ..Captopril stimulated peripheral renin and postcaptopril renography are not useful as screening tools for the diagnosis of renovascular disease in blacks. Blacks at high risk should be evaluated with angiography...
  22. ncbi request reprint Informing cancer prevention strategies for African Americans: the relationship of African American acculturation to fruit, vegetable, and fat intake
    Jamy D Ard
    Duke Hypertension Center and the Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, USA
    J Behav Med 28:239-47. 2005
    ..This pattern was supported by differences in the ANOVA. African American acculturation is related to dietary intake. These findings have implications for the design of cancer-related public health messages targeted to African Americans...
  23. ncbi request reprint Diet and blood pressure: applying the evidence to clinical practice
    Jamy D Ard
    Duke Hypertension Center, Duke University Medical Center, Durham, NC, USA
    Am Heart J 149:804-12. 2005
  24. ncbi request reprint Perceptions of African-American culture and implications for clinical trial design
    Jamy D Ard
    Duke Hypertension Center, Duke University Medical Center, Durham, North Carolina, USA
    Ethn Dis 15:292-9. 2005
    ..To identify unique cultural variables for African Americans that might limit the effectiveness of behavioral interventions in clinical trials...
  25. ncbi request reprint A dietary pattern that lowers oxidative stress increases antibodies to oxidized LDL: results from a randomized controlled feeding study
    Edgar R Miller
    Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins Medical Institutions, 2024 East Monument Street, Suite 2 624, Baltimore, MD 21205 2223, USA
    Atherosclerosis 183:175-82. 2005
    ..We tested the hypothesis that consumption of a healthy diet rich in fruits and vegetables and reduced in saturated fat, total fat, and cholesterol will concomitantly reduce oxidative stress and Ab-oxLDL...
  26. ncbi request reprint The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design
    Andrea M Haqq
    Sarah W Stedman Nutrition and Metabolism Center, Duke University, Durham, NC 27705, USA
    Contemp Clin Trials 26:616-25. 2005
    ..Results from this study will expand our knowledge of the biology of obesity and weight regulation and may lead to targeted strategies for its treatment and control...
  27. ncbi request reprint Effects of comprehensive lifestyle modification on diet, weight, physical fitness, and blood pressure control: 18-month results of a randomized trial
    Patricia J Elmer
    Kaiser Permanente Northwest, Portland, Oregon 97227, USA
    Ann Intern Med 144:485-95. 2006
    ..The main 6-month results from the PREMIER trial showed that comprehensive behavioral intervention programs improve lifestyle behaviors and lower blood pressure...
  28. ncbi request reprint Effects of individual components of multiple behavior changes: the PREMIER trial
    Eva Obarzanek
    National Heart, Lung, and Blood Institute, Bethesda, MD 20892 7936, USA
    Am J Health Behav 31:545-60. 2007
    ..To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes...
  29. ncbi request reprint Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome
    Lillian F Lien
    Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, NC 27710, USA
    Hypertension 50:609-16. 2007
    ..Our data suggest that strategies for lowering BP in individuals with metabolic syndrome may be enhanced by recommendations to adopt the DASH dietary pattern...
  30. doi request reprint Effect of group racial composition on weight loss in African Americans
    Jamy D Ard
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Obesity (Silver Spring) 16:306-10. 2008
    ..We tested the hypothesis that AA who participate in all AA weight loss intervention groups will lose more weight than AA who participate in mixed race groups...
  31. ncbi request reprint Effect of socioeconomic status on food availability and cost of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern
    Christopher M Young
    From the Department of Obstetrics and Gynecology, McGaw Medical Center of Northwestern University, Chicago, IL, USA
    J Clin Hypertens (Greenwich) 10:603-11. 2008
    ..Eating the DASH diet, however, is more expensive in high-SES communities. Increased information, food availability, and affordability are likely to lead to more widespread adoption of the DASH diet...
  32. ncbi request reprint The Take Control of Your Blood pressure (TCYB) study: study design and methodology
    Hayden B Bosworth
    Center for Health Services Research in Primary Care, Durham VAMC, Durham NC 27703, USA
    Contemp Clin Trials 28:33-47. 2007
    ..Despite the damaging impact of hypertension and the availability of evidence-based target values for blood pressure, interventions to improve blood pressure control have had limited success...
  33. ncbi request reprint Predictors of proteinuria and renal failure among women with HIV infection
    Lynda Anne Szczech
    Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Kidney Int 61:195-202. 2002
    ..This study examines the risk factors for proteinuria and renal failure in a large cohort of HIV-infected women not selected for the presence of renal disease...
  34. ncbi request reprint Sodium and blood pressure: no data dredging, please!
    Frank M Sacks
    Am J Hypertens 16:614-6. 2003
  35. ncbi request reprint A new model for developing and executing culturally appropriate behavior modification clinical trials for African Americans
    Jamy D Ard
    Duke Hypertension Center, Duke University Medical Center, Durham, NC 27710, USA
    Ethn Dis 13:279-85. 2003
    ..In addition, investigators must understand how to effectively address relevant biases of African Americans without challenging their ethnic identity. Steps to decrease biases are described...
  36. ncbi request reprint Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship
    Sachie Akita
    Department of Internal Medicine and Pathophysiology, Nagoya City University Graduate School of Medical Sciences, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
    Hypertension 42:8-13. 2003
    ..5+/-3.4 vs 64.9+/-13.1 [mmol/d]/mm Hg, P=0.0002) without significantly shifting the x-intercept (94.1+/-0.5 vs 93.2+/-0.6 mm Hg, NS) of the relationship. These data suggest a natriuretic action of the DASH diet...
  37. ncbi request reprint The DASH diet enhances the blood pressure response to losartan in hypertensive patients
    Paul R Conlin
    Division of Endocrinology, Diabetes and Hypertension PRC, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Hypertens 16:337-42. 2003
    ..We conducted a clinical trial to assess the BP response to the DASH diet with an antihypertensive medication, losartan, in participants with essential hypertension...
  38. ncbi request reprint Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial
    Lawrence J Appel
    Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Md 21205 2233, USA
    JAMA 289:2083-93. 2003
    ..The Dietary Approaches to Stop Hypertension (DASH) diet also lowers BP. To date, no trial has evaluated the effects of simultaneously implementing these lifestyle recommendations...
  39. ncbi request reprint Blood pressure effects of vitamin C: what's the key question?
    Laura P Svetkey
    Hypertension 40:789-91. 2002
  40. ncbi request reprint Church rosters: is this a viable mechanism for effectively recruiting African Americans for a community-based survey?
    Lori Carter-Edwards
    Rho, Inc, Chapel Hill, NC 27514, USA
    Ethn Health 7:41-55. 2002
    ..The purpose of this report is to describe the process, results, and implications in the phone recruitment of African Americans through church rosters for a survey of diet-and blood pressure-related awareness and hypertension prevalence...
  41. ncbi request reprint Diet- and blood pressure-related knowledge, attitudes, and hypertension prevalence among African Americans: the KDBP Study. Knowledge of Diet and Blood Pressure
    Lori Carter-Edwards
    Rho, Inc, Chapel Hill, North Carolina 27514, USA
    Ethn Dis 12:S1-72-82. 2002
    ..Further exploration of attitudes and socioeconomic factors in assessing health awareness and HTN prevalence in this population is recommended...
  42. ncbi request reprint One-year follow-up study of blood pressure and dietary patterns in dietary approaches to stop hypertension (DASH)-sodium participants
    Jamy D Ard
    Duke Hypertension Center, Duke University Medical Center, Durham, North Carolina, USA
    Am J Hypertens 17:1156-62. 2004
    ....
  43. ncbi request reprint The potential impact of nonpharmacologic population-wide blood pressure reduction on coronary heart disease events: pronounced benefits in African-Americans and hypertensives
    Thomas P Erlinger
    Welch Center for Prevention, Epidemiology and Clinical Research, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    Prev Med 37:327-33. 2003
    ..However, several nonpharmacologic interventions reduce BP to a greater degree in hypertensives and African-Americans...
  44. ncbi request reprint The clinical epidemiology and course of the spectrum of renal diseases associated with HIV infection
    Lynda Anne Szczech
    Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Kidney Int 66:1145-52. 2004
    ..This study was undertaken to compare HIVAN to the spectrum of other kidney diseases seen among HIV-infected patients...
  45. ncbi request reprint Comprehensive lifestyle modification and blood pressure control: a review of the PREMIER trial
    Heather L McGuire
    Division of Nephrology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Hypertens (Greenwich) 6:383-90. 2004
    ..001) compared with a decrease to 26% in the advice-only group. The PREMIER trial demonstrated that persons with above-optimal BP and stage 1 hypertension can make multiple lifestyle changes leading to better control of BP...
  46. ncbi request reprint A further subgroup analysis of the effects of the DASH diet and three dietary sodium levels on blood pressure: results of the DASH-Sodium Trial
    George A Bray
    Pennington Biomedical Research Center, Baton Rouge, Lousiana, USA
    Am J Cardiol 94:222-7. 2004
    ....
  47. pmc Weight loss during the intensive intervention phase of the weight-loss maintenance trial
    Jack F Hollis
    Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon 97227, USA
    Am J Prev Med 35:118-26. 2008
    ..This paper describes methods and results for the initial 6-month weight-loss program (Phase I)...
  48. ncbi request reprint The effect of the PREMIER interventions on insulin sensitivity
    Jamy D Ard
    Duke Hypertension Center, Duke University Medical Center, and Center for Health Services Research in Primary Care, VA Medical Center, Durham, North Carolina, USA
    Diabetes Care 27:340-7. 2004
    ..This ancillary study of PREMIER sought to determine the effects on insulin sensitivity of a comprehensive behavioral intervention for hypertension with and without the Dietary Approaches to Stop Hypertension (DASH) dietary pattern...
  49. ncbi request reprint The DASH diet and blood pressure
    Shirley R Craddick
    Kaiser Permanente Center for Health Research, 3800 North Interstate, Portland, OR 97227, USA
    Curr Atheroscler Rep 5:484-91. 2003
    ..The DASH diet should be promoted, along with maintaining healthy weight, reducing sodium intake, increasing regular physical activity, and limiting alcohol intake, for lowering blood pressure and reducing the risk of CVD...
  50. ncbi request reprint The DASH diet and sodium reduction improve markers of bone turnover and calcium metabolism in adults
    Pao Hwa Lin
    Department of Medicine, Sarah W Stedman Center for Nutritional Studies, Duke University Medical Center, Durham, NC, USA
    J Nutr 133:3130-6. 2003
    ..A reduced sodium intake reduced calcium excretion in both diet groups and serum OC in the DASH group. The DASH diet and reduced sodium intake may have complementary, beneficial effects on bone health...
  51. ncbi request reprint Definition of proteinuria among women with HIV infection
    Lynda Anne Szczech
    Kidney Int 65:1519. 2004
  52. ncbi request reprint Effect of dietary sodium intake on blood lipids: results from the DASH-sodium trial
    David W Harsha
    Pennington Biomedical Research Center, Baton Rouge, LA, USA
    Hypertension 43:393-8. 2004
    ..There were no significant interactions between the effects of sodium and the DASH diet on serum lipids. In conclusion, changes in dietary sodium intake over the range of 50 to 150 mmol/d did not affect blood lipid concentrations...
  53. ncbi request reprint Individual blood pressure responses to changes in salt intake: results from the DASH-Sodium trial
    Eva Obarzanek
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 8136, MSC 7936, Bethesda, MD 20892 7936, USA
    Hypertension 42:459-67. 2003
    ....

Research Grants13

  1. PREMIER Maintenance Trial(MAINTENANCE)
    Laura Svetkey; Fiscal Year: 2007
    ..The purpose of this proposal is to develop and test two such interventions, which, if effective, should complement ongoing efforts to stem the obesity epidemic and ultimately prevent obesity-related CVD. ..
  2. WEIGHT LOSS MAINTENANCE TRIAL
    Laura Svetkey; Fiscal Year: 2007
    ..The purpose of this proposal is to develop and test two such interventions, which, if effective, should complement ongoing efforts to stem the obesity epidemic and ultimately prevent obesity-related CVD. ..
  3. Hypertension Improvement Project (HIP)
    Laura Svetkey; Fiscal Year: 2007
    ..3 for the primary outcome. The HIP study will test practical interventions for improving hypertension control that can be broadly implemented and reduce CVD risk. ..
  4. The DASH-Sodium Trial: Genetic Determinants of Response
    Laura Svetkey; Fiscal Year: 2004
    ..Ultimately, increased understanding of these mechanisms will lead to improved strategies for prevention and control, both nutritional and pharmacologic, of high BP. ..
  5. PREMIER--LIFESTYLE INTERVENTION BLOOD PRESSURE CONTROL
    Laura Svetkey; Fiscal Year: 2002
    ..Results from PREMIER will provide the scientific rationale for routinely implementing comprehensive lifestyle intervention programs to control BP and ultimately prevent BP related cardiovascular disease. ..
  6. Hypertension Improvement Project(HIP)
    Laura Svetkey; Fiscal Year: 2007
    ..3 for the primary outcome. The HIP study will test practical interventions for improving hypertension control that can be broadly implemented and reduce CVD risk. ..