G Samsa

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi Hypertension Improvement Project (HIP): study protocol and implementation challenges
    Rowena J Dolor
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Trials 10:13. 2009
  2. ncbi Epidemiology of recurrent cerebral infarction: a medicare claims-based comparison of first and recurrent strokes on 2-year survival and cost
    G P Samsa
    Center for Clinical Health Policy Research, and the Departments of Community and Family Medicine and Medicine, Duke University School of Medicine Durham, NC, USA
    Stroke 30:338-49. 1999
  3. ncbi Effect of moderate weight loss on health-related quality of life: an analysis of combined data from 4 randomized trials of sibutramine vs placebo
    G P Samsa
    Departments of Community and Family Medicine, Center for Clinical Health Policy Research, Duke University Medical Center, Durham, NC, USA
    Am J Manag Care 7:875-83. 2001
  4. ncbi Quality of anticoagulation management among patients with atrial fibrillation: results of a review of medical records from 2 communities
    G P Samsa
    Center for Clinical Health Policy Research, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
    Arch Intern Med 160:967-73. 2000
  5. ncbi Relationship between test frequency and outcomes of anticoagulation: a literature review and commentary with implications for the design of randomized trials of patient self-management
    G P Samsa
    Center for Clinical Health Policy Research, Department of Medicine, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27705, USA
    J Thromb Thrombolysis 9:283-92. 2000
  6. ncbi Cost-effectiveness of ancrod treatment of acute ischaemic stroke: results from the Stroke Treatment with Ancrod Trial (STAT)
    Gregory P Samsa
    Center for Clinical Health Policy Research, Suite 230, Duke University, 2200 West Main Street, Durham, NC 27705, USA
    J Eval Clin Pract 8:61-70. 2002
  7. ncbi Use of data from nonrandomized trial designs in evidence reports: an application to treatment of pulmonary disease following spinal cord injury
    Gregory P Samsa
    Center for Clinical Health Policy Research, Duke University, Medical Center, Durham, NC 27705, USA
    J Rehabil Res Dev 39:41-52. 2002
  8. ncbi Determining clinically important differences in health status measures: a general approach with illustration to the Health Utilities Index Mark II
    G Samsa
    Center for Clinical Health Policy Research, Duke University School of Medicine, Durham, North Carolina, USA
    Pharmacoeconomics 15:141-55. 1999
  9. ncbi A cost-minimization analysis comparing azithromycin-based and levofloxacin-based protocols for the treatment of patients hospitalized with community-acquired pneumonia: results from the CAP-IN trial
    Gregory P Samsa
    Center for Clinical Health Policy Research, Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27705, USA
    Chest 128:3246-54. 2005
  10. ncbi Have randomized controlled trials of neuroprotective drugs been underpowered? An illustration of three statistical principles
    G P Samsa
    Center for Clinical Health Policy Research, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
    Stroke 32:669-74. 2001

Detail Information

Publications78

  1. ncbi Hypertension Improvement Project (HIP): study protocol and implementation challenges
    Rowena J Dolor
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Trials 10:13. 2009
    ..The chronic care model suggests that blood pressure control can be achieved by improving how patients and physicians address patient self-care...
  2. ncbi Epidemiology of recurrent cerebral infarction: a medicare claims-based comparison of first and recurrent strokes on 2-year survival and cost
    G P Samsa
    Center for Clinical Health Policy Research, and the Departments of Community and Family Medicine and Medicine, Duke University School of Medicine Durham, NC, USA
    Stroke 30:338-49. 1999
    ..The extent of this difference has, however, not yet been estimated with precision...
  3. ncbi Effect of moderate weight loss on health-related quality of life: an analysis of combined data from 4 randomized trials of sibutramine vs placebo
    G P Samsa
    Departments of Community and Family Medicine, Center for Clinical Health Policy Research, Duke University Medical Center, Durham, NC, USA
    Am J Manag Care 7:875-83. 2001
    ....
  4. ncbi Quality of anticoagulation management among patients with atrial fibrillation: results of a review of medical records from 2 communities
    G P Samsa
    Center for Clinical Health Policy Research, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
    Arch Intern Med 160:967-73. 2000
    ..Although many studies have addressed the proportion of eligible patients with atrial fibrillation (AF) receiving warfarin sodium, few have addressed the quality of their anticoagulation management...
  5. ncbi Relationship between test frequency and outcomes of anticoagulation: a literature review and commentary with implications for the design of randomized trials of patient self-management
    G P Samsa
    Center for Clinical Health Policy Research, Department of Medicine, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27705, USA
    J Thromb Thrombolysis 9:283-92. 2000
    ....
  6. ncbi Cost-effectiveness of ancrod treatment of acute ischaemic stroke: results from the Stroke Treatment with Ancrod Trial (STAT)
    Gregory P Samsa
    Center for Clinical Health Policy Research, Suite 230, Duke University, 2200 West Main Street, Durham, NC 27705, USA
    J Eval Clin Pract 8:61-70. 2002
    ....
  7. ncbi Use of data from nonrandomized trial designs in evidence reports: an application to treatment of pulmonary disease following spinal cord injury
    Gregory P Samsa
    Center for Clinical Health Policy Research, Duke University, Medical Center, Durham, NC 27705, USA
    J Rehabil Res Dev 39:41-52. 2002
    ....
  8. ncbi Determining clinically important differences in health status measures: a general approach with illustration to the Health Utilities Index Mark II
    G Samsa
    Center for Clinical Health Policy Research, Duke University School of Medicine, Durham, North Carolina, USA
    Pharmacoeconomics 15:141-55. 1999
    ..This makes interpretation of HR-QOL results from clinical trials difficult, and having a benchmarking process which is relatively straightforward would be highly desirable...
  9. ncbi A cost-minimization analysis comparing azithromycin-based and levofloxacin-based protocols for the treatment of patients hospitalized with community-acquired pneumonia: results from the CAP-IN trial
    Gregory P Samsa
    Center for Clinical Health Policy Research, Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27705, USA
    Chest 128:3246-54. 2005
    ..A randomized trial was performed comparing azithromycin and levofloxacin for treating moderately to severely ill patients hospitalized with community-acquired pneumonia. This is a cost-minimization analysis comparing those regimens...
  10. ncbi Have randomized controlled trials of neuroprotective drugs been underpowered? An illustration of three statistical principles
    G P Samsa
    Center for Clinical Health Policy Research, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
    Stroke 32:669-74. 2001
    ..The results of phase III trials of neuroprotective drugs for acute ischemic stroke have been disappointing. We examine the question of whether these trials may have been underpowered...
  11. ncbi How strong is the relationship between functional status and quality of life among persons with stroke?
    Gregory P Samsa
    Center for Clinical Health Policy Research, Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27705, USA
    J Rehabil Res Dev 41:279-82. 2004
    ..Quality of life with major stroke may not necessarily be as low as that reported before such a stroke occurs. Quality of life after stroke is heterogeneous and depends on more than just level of physical function...
  12. ncbi A new instrument for measuring anticoagulation-related quality of life: development and preliminary validation
    Greg Samsa
    Department of Biometry and Bioinformatics, Duke University Medical Center, Wachovia Plaza, Suite 220, 2200 West Main Street, Durham, NC 27705, USA
    Health Qual Life Outcomes 2:22. 2004
    ..We describe the development and preliminary validation of such an instrument - the Duke Anticoagulation Satisfaction Scale (DASS)...
  13. ncbi Which approach to anticoagulation management is best? Illustration of an interactive mathematical model to support informed decision making
    Gregory P Samsa
    Center for Clinical Health Policy Research, Duke University Medical Center, Durham, NC, USA
    J Thromb Thrombolysis 14:103-11. 2002
    ..The Anticoagulation Management Event/Cost Model (ACME) is an interactive mathematical model intended to help clarify these trade-offs...
  14. ncbi Disability fingerprints: patterns of disability in spinal cord injury and multiple sclerosis differ
    H Hoenig
    Physical Medicine and Rehabilitation Service, Durham Veterans Administration Medical Center, North Carolina 27705, USA
    J Gerontol A Biol Sci Med Sci 54:M613-20. 1999
    ..quot; Multiple sclerosis (MS) and Spinal Cord Injury (SCI) both affect the spinal cord; however, their pathophysiologies differ (progressive vs. nonprogressive; multifocal vs. unifocal)...
  15. ncbi VA Stroke Study: neurologist care is associated with increased testing but improved outcomes
    L B Goldstein
    Durham VA Medical Center, Durham, NC, USA
    Neurology 61:792-6. 2003
    ..VA Stroke Study (VASt) data were analyzed to determine whether neurologist management affected the process and outcome of care of patients with ischemic stroke...
  16. ncbi Hormone replacement therapy and ischemic stroke severity in women: a case-control study
    C D Bushnell
    Duke Center for Cerebrovascular Disease, Department of Medicine Neurology Duke University Medical Center, Durham, NC 27710, USA
    Neurology 56:1304-7. 2001
    ..To investigate whether ischemic stroke severity differed among women who were receiving hormone replacement therapy (HRT) as compared with those who were not receiving these drugs...
  17. ncbi Relationship between self-reported disability and caregiver hours
    G P Samsa
    Center for Clinical Health Policy Research, and Department of Medicine, Duke University Medical Center, Durham, North Carolina 27705, USA
    Am J Phys Med Rehabil 80:674-84. 2001
    ....
  18. ncbi Cost of multiple sclerosis by level of disability: a review of literature
    M B Patwardhan
    Duke Center for Clinical Health Policy Research, Duke University Medical Center, Durham, NC 27705, USA
    Mult Scler 11:232-9. 2005
    ....
  19. ncbi Reasons for quitting smoking among low-income African American smokers
    C M McBride
    Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710 2949, USA
    Health Psychol 20:334-40. 2001
    ..Refinement of the RFQ is needed to assess intrinsic motivators other than health concerns and to identify salient motivators for young and male smokers...
  20. ncbi Factors associated with repeat mammography screening
    S Halabi
    Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Fam Pract 49:1104-12. 2000
    ....
  21. ncbi Studies of a targeted risk reduction intervention through defined exercise (STRRIDE)
    W E Kraus
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Med Sci Sports Exerc 33:1774-84. 2001
    ....
  22. ncbi Racial differences in survival post cerebral infarction among the elderly
    J Bian
    Department of Health Policy and Administration, University of North Carolina at Chapel Hill, Durham, 27705, USA
    Neurology 60:285-90. 2003
    ..Future analyses, using more clinically detailed data, should focus especially on whether survival differences by race persist in the young-old (age 65 to 74) population...
  23. ncbi Multicenter review of preoperative risk factors for endarterectomy for asymptomatic carotid artery stenosis
    L B Goldstein
    Center for Clinical Health Policy Research, Division of Neurology, Duke University, Department of Veterans Affairs Medical Center, Durham, NC, USA
    Stroke 29:750-3. 1998
    ..The purpose of this study was to analyze the impact of potential preoperative risk factors on the frequency of postoperative complications in patients undergoing the operation for asymptomatic disease in academic medical centers...
  24. ncbi US National Survey of Physician Practices for the Secondary and Tertiary Prevention of Ischemic Stroke. Carotid endarterectomy
    L B Goldstein
    Center for Health Policy Research and Education, Duke University, Durham, NC, USA
    Stroke 27:801-6. 1996
    ..Yet, there are few data concerning the patterns of use of CE by physicians for their patients at risk for stroke. These data are critical for the rational allocation of resources and targeting of educational efforts...
  25. ncbi US National Survey of Physician Practices for the Secondary and Tertiary Prevention of Ischemic Stroke. Medical therapy in patients with carotid artery stenosis
    L B Goldstein
    Center for Health Policy Research and Education, Duke University, Durham, NC USA
    Stroke 27:1473-8. 1996
    ..The identification of variations in practice may help to both direct specific educational efforts and guide further research...
  26. ncbi Reliability of the National Institutes of Health Stroke Scale. Extension to non-neurologists in the context of a clinical trial
    L B Goldstein
    Division of Neurology, Duke University Medical Center, Durham, NC 27710, USA
    Stroke 28:307-10. 1997
    ..This reliability testing has primarily focused on the use of the scale by neurologists. We sought to determine the reliability of the NIHSS as used by non-neurologists in the context of a clinical trial...
  27. ncbi Using outcomes data to identify best medical practice: the role of policy models
    D B Matchar
    Center for Clinical Health Policy Research, Duke University Medical Center, Durham, NC 27705, USA
    Hepatology 29:36S-39S. 1999
    ..The SPPM is a simulation model designed to predict the best among various treatment alternatives for preventing strokes. Similar models can be applied to treatment outcomes for liver disease...
  28. ncbi The role of evidence reports in evidence-based medicine: a mechanism for linking scientific evidence and practice improvement
    D B Matchar
    Center for Clinical Health Policy Research, Duke University, USA
    Jt Comm J Qual Improv 25:522-8. 1999
    ..That is, while information synthesis should be global, implementation must be local...
  29. ncbi New transient ischemic attack and stroke: outpatient management by primary care physicians
    L B Goldstein
    Department of Medicine Neurology, Box 3651, Duke University Medical Center, Durham, NC 27710
    Arch Intern Med 160:2941-6. 2000
    ..The purpose of the present study was to identify a group of patients seen by primary care physicians in an office setting for a first-ever TIA or stroke and characterize their evaluation and management...
  30. ncbi A comparison of three health status measures in primary care outpatients
    D Edelman
    Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, NC 27705, USA
    J Gen Intern Med 14:759-62. 1999
    ..These three health service measures varied in their distribution of responses and ttime required to complete. Users should consider the degree of sickness of the population to be assessed when choosing a measure...
  31. ncbi Differences in skeletal muscle between men and women with chronic heart failure
    B D Duscha
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Appl Physiol 90:280-6. 2001
    ..These observations were not reproduced in CHF women. This suggests that differences may exist in how skeletal muscle adapts to decreasing peak VO(2) in patients with CHF...
  32. ncbi Predicting the outcomes of electrophysiologic studies of patients with unexplained syncope: preliminary validation of a derived model
    M Linzer
    Department of Medicine, Duke University Medical Center, Durham, North Carolina
    J Gen Intern Med 6:113-20. 1991
    ....
  33. ncbi A nurse-coordinated intervention for primary care patients with non-insulin-dependent diabetes mellitus: impact on glycemic control and health-related quality of life
    M Weinberger
    Center for Health Services Research in Primary Care, Durham VAMC, NC, USA
    J Gen Intern Med 10:59-66. 1995
    ..66) or diabetes-related symptoms (p = 0.23). CONCLUSIONS: The intervention, designed to be a pragmatic, low-intensity adjunct to care delivered by physicians, modestly improved glycemic control but not HRQOL or diabetes-related symptoms...
  34. ncbi Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity
    R S Bedlack
    Duke University Medical Center and Durham VAMC, Durham, NC, USA
    Neurology 64:1968-70. 2005
    ..Our results support QMG use for assessing clinical change in trials...
  35. ncbi General performance on a numeracy scale among highly educated samples
    I M Lipkus
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27701, USA
    Med Decis Making 21:37-44. 2001
    ..Here, we examine how highly educated participants performed on a general and an expanded numeracy scale. The latter was designed within the context of health risks...
  36. ncbi Accuracy and reliability of apical S3 gallop detection
    E C Westman
    Center for Health Services Research in Primary Care, Duke University, Durham, North Carolina 27705, USA
    J Gen Intern Med 10:455-7. 1995
    ..Sensitivity was lower for detecting soft S3 gallops, and specificity was lower when a diastolic murmur was also present. Physician performance in detecting apical S3 gallops is variable, but can be excellent...
  37. ncbi Two-year trends in physical performance following supervised exercise among community-dwelling older veterans
    M C Morey
    Geriatric Research, Education and Clinical Center GRECC, VA Medical Center, Durham, NC 27705
    J Am Geriatr Soc 39:986-92. 1991
    ..02). Strength variables did not improve. The study indicates that improvements in cardiovascular function and flexibility achieved by the elderly in the early stages of an exercise program can be maintained for at least 2 years...
  38. ncbi Effects of ocular carteolol and timolol on plasma high-density lipoprotein cholesterol level
    S F Freedman
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina
    Am J Ophthalmol 116:600-11. 1993
    ..There was no differential drug effect on the other lipid variables measured. Ocular nonselective beta-adrenergic antagonist therapy can produce clinically relevant decrements in high-density lipoprotein cholesterol levels in healthy men...
  39. ncbi Facilitated process improvement: an approach to the seamless linkage between evidence and practice in CKD
    David B Matchar
    Duke Center for Clinical Health Policy Research, Durham, NC, USA
    Am J Kidney Dis 47:528-38. 2006
    ..Prespecified tools fail to accommodate local circumstances, TQM requires an unrealistic level of local commitment, and neither has a proven track record for success...
  40. ncbi Point-of-care testing of the international normalized ratio in patients with antiphospholipid antibodies
    Stephanie L Perry
    Division of Hematology, Department of Medicine, Department of Pathology, Duke University Health System, Durham, North Carolina 27710, USA
    Thromb Haemost 94:1196-202. 2005
    ..For this subset of APS patients, we suggest using an alternative method to monitor warfarin...
  41. ncbi Impact of hormone replacement therapy on exercise training-induced improvements in insulin action in sedentary overweight adults
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Metabolism 57:888-95. 2008
    ..These findings have implications for the relative utility of ET for improving insulin action in middle-aged men and women, particularly in the setting of differences in HRT use...
  42. ncbi Cost-effectiveness of antiplatelet agents in secondary stroke prevention: the limits of certainty
    David B Matchar
    Center for Clinical Health Policy Research, Duke University, Durham, NC 27705, USA
    Value Health 8:572-80. 2005
    ..Which of the available antiplatelet therapies should be preferred for secondary prevention of recurrent ischemic stroke has been contentious...
  43. ncbi Linking dementia research to policy: an example using fluorodeoxyglucose positron emission tomography for the diagnosis of Alzheimer's dementia and mild cognitive impairment
    Shalini L Kulasingam
    Am J Alzheimers Dis Other Demen 21:73-8. 2006
  44. ncbi Advanced chronic kidney disease practice patterns among nephrologists and non-nephrologists: a database analysis
    Meenal B Patwardhan
    Duke Center for Clinical Health Policy Research, 2200 W Main Street, Suite 220, Durham, NC 27705, USA
    Clin J Am Soc Nephrol 2:277-83. 2007
    ..Management of advanced CKD is suboptimal for all patients but is particularly poor for patients who are treated solely by non-nephrologists...
  45. ncbi Assessing weight-related quality of life in adolescents
    Ronette L Kolotkin
    Obesity and Quality of Life Consulting, 1004 Norwood Avenue, Durham, NC 27707, USA
    Obesity (Silver Spring) 14:448-57. 2006
    ..The development of a new weight-related measure to assess quality of life in adolescents [Impact of Weight on Quality of Life (IWQOL)-Kids] is described...
  46. ncbi Opportunities for improving management of advanced chronic kidney disease
    Meenal B Patwardhan
    Duke Center for Clinical Health Policy Research, Duke University Medical Center, and Veterans Administration Health Services Research, Durham, NC 27705, USA
    Am J Med Qual 23:184-92. 2008
    ....
  47. ncbi Exercise training amount and intensity effects on metabolic syndrome (from Studies of a Targeted Risk Reduction Intervention through Defined Exercise)
    Johanna L Johnson
    Department of Medicine, Division of Cardiology, Duke University Medical Center and Duke Center for Living, Durham, North Carolina, USA
    Am J Cardiol 100:1759-66. 2007
    ..A higher amount of vigorous exercise had greater and more widespread benefits. Finally, there was an indication that moderate-intensity may be better than vigorous-intensity exercise for improving MS...
  48. ncbi Assessing the quality of colorectal cancer care: do we have appropriate quality measures? (A systematic review of literature)
    Meenal Patwardhan
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    J Eval Clin Pract 13:831-45. 2007
    ..We also evaluated the extent to which these measures are ready to be implemented in clinical practice, and identified areas for future research...
  49. ncbi Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension
    David B Matchar
    Duke Center for Clinical Health Policy Research, Duke Clinical Research Institute, Duke University, and Durham U S Department of Veterans Affairs Medical Center, Durham, North Carolina 27705, USA
    Ann Intern Med 148:16-29. 2008
    ..The relative effectiveness of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) for lowering blood pressure is unknown...
  50. ncbi Dietary carbohydrate intake and high-sensitivity C-reactive protein in at-risk women and men
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am Heart J 154:962-8. 2007
    ..Our objective was to determine if GL is related to hsCRP and other measures of CVD risk in a population of sedentary, overweight, dyslipidemic middle-aged women and men enrolled in an exercise intervention trial (STRRIDE)...
  51. ncbi Headache management program improves outcome for chronic headache
    Linda H Harpole
    Department of Medicine, Center for Clinical Health Policy Research, Duke University Medical Center, First Union Tower, Suite 220, 2200 West Main Street, Durham, NC 27705, USA
    Headache 43:715-24. 2003
    ..We currently are conducting a randomized controlled trial to better evaluate the clinical and financial impact of a headache management program for patients with chronic headache...
  52. ncbi Quality measures for the use of adjuvant chemotherapy and radiation therapy in patients with colorectal cancer: a systematic review
    Robert G Prosnitz
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Cancer 107:2352-60. 2006
    ..Therefore, the authors conducted a systematic review of the literature to determine the available QMs for adjuvant CT and RT in patients with CRC and rated their usefulness for assessing the delivery of quality care...
  53. ncbi Response of high-sensitivity C-reactive protein to exercise training in an at-risk population
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am Heart J 152:793-800. 2006
    ..Our objective was to determine if modulating fitness with exercise training imposes changes in high-sensitivity C-reactive protein in a mixed-sex population at risk for cardiovascular disease...
  54. ncbi Increasing colorectal cancer screening among individuals in the carpentry trade: test of risk communication interventions
    Isaac M Lipkus
    Department of Psychiatry, Duke University, Medical Center, PO Box 2949, Durham NC 27710, USA
    Prev Med 40:489-501. 2005
    ....
  55. ncbi How can modeling best contribute to the assessment of secondary stroke prevention strategies?
    David B Matchar
    Am J Med 118:198-9; author reply 199. 2005
  56. ncbi Veterans Administration Acute Stroke (VASt) Study: lack of race/ethnic-based differences in utilization of stroke-related procedures or services
    Larry B Goldstein
    Durham Veterans Affairs Medical Center, Durham, NC, USA
    Stroke 34:999-1004. 2003
    ....
  57. ncbi Effects of the amount and intensity of exercise on plasma lipoproteins
    William E Kraus
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    N Engl J Med 347:1483-92. 2002
    ..However, the amount of exercise training required for optimal benefit is unknown. In a prospective, randomized study, we investigated the effects of the amount and intensity of exercise on lipoproteins...
  58. ncbi Structure, process, and outcomes in stroke rehabilitation
    Helen Hoenig
    Durham VA Medical Center and Department of Medicine, Duke University Medical Center, Durham, North Carolina 27705, USA
    Med Care 40:1036-47. 2002
    ..However, little empirical work has been done to test this hypothesis, particularly for medical rehabilitation...
  59. ncbi Performance of a mail-administered version of a stroke-specific outcome measure, the Stroke Impact Scale
    Pamela W Duncan
    Department of Research, Department of Veterans Affairs Medical Center, Center on Aging, University of Kansas Medical Center, Room 5026 Wescoe Pavilion, 3901 Rainbow Blvd, Kansas City, Kansas 66160 7117, USA
    Clin Rehabil 16:493-505. 2002
    ..To evaluate the feasibility and concurrent validity of a new, mail-administered, stroke-specific outcome measure, the Stroke Impact Scale (SIS)...
  60. ncbi Improving the quality of anticoagulation of patients with atrial fibrillation in managed care organizations: results of the managing anticoagulation services trial
    David B Matchar
    Center for Clinical Health Policy Research, Duke University, Durham, NC 27705, USA
    Am J Med 113:42-51. 2002
    ....
  61. ncbi Postacute stroke guideline compliance is associated with greater patient satisfaction
    Dean M Reker
    Kansas City VA Medical Center and Center on Aging, University of Kansas Medical Center, Kansas City, KS 64128, USA
    Arch Phys Med Rehabil 83:750-6. 2002
    ..To determine if the structure of care or the process of stroke care, as measured by compliance with stroke guidelines published by the Agency for Healthcare Research and Quality (AHRQ), is associated with patient satisfaction...
  62. ncbi Effects of a mammography decision-making intervention at 12 and 24 months
    Barbara K Rimer
    Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland 20852, USA
    Am J Prev Med 22:247-57. 2002
    ..Numerous groups have called for informed decision making about mammography, but few programs have resulted. Our research is intended to fill this gap...
  63. ncbi Adherence to postacute rehabilitation guidelines is associated with functional recovery in stroke
    Pamela W Duncan
    Kansas City VA Medical Center and Center on Aging, The University of Kansas Medical Center, Kansas City 66160 7117, USA
    Stroke 33:167-77. 2002
    ..The purpose of this study was to determine if compliance with poststroke rehabilitation guidelines was associated with better functional outcomes...
  64. ncbi Cancer incidence among union carpenters in New Jersey
    John Dement
    Division of Occupational and Environmental Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Occup Environ Med 45:1059-67. 2003
    ..48) in analyses that lagged results 15 years from initial union membership. Additional etiologic research is needed to evaluate possible occupational and nonoccupational risk factors for testicular cancer...
  65. ncbi Modifying attributions of colorectal cancer risk
    Isaac M Lipkus
    Duke University Medical Center, 905 West Main Street, Box 34, Durham, NC 27701, USA
    Cancer Epidemiol Biomarkers Prev 13:560-6. 2004
    ....
  66. ncbi A clinical decision and economic analysis model of cancer pain management
    Amy P Abernethy
    Center for Clinical Health Policy Research, Department of Medicine, Duke University Medical Center, 2200 W Main St, Suite 230, Durham, NC 27705, USA
    Am J Manag Care 9:651-64. 2003
    ..CONCLUSION: Guideline-based cancer pain management leads to improved pain control with modest increases in resource use...
  67. ncbi Accuracy of self-reports of fecal occult blood tests and test results among individuals in the carpentry trade
    Isaac M Lipkus
    Duke University Medical Center, Durham, NC 27701, USA
    Prev Med 37:513-9. 2003
    ....
  68. ncbi Gender and racial differences in lipoprotein subclass distributions: the STRRIDE study
    Johanna L Johnson
    Divisions of Cardiology, Duke Center for Living, Duke University Medical Center, 1300 Morreene Road, DUMC Box 3022 Durham, NC 27710, USA
    Atherosclerosis 176:371-7. 2004
    ..Within this homogenous population, there were distinct differences between gender and racial groups. Blacks and women had less atherogenic profiles than whites and men, which was not evident from the standard lipid panel...
  69. ncbi When should functional neuroimaging techniques be used in the diagnosis and management of Alzheimer's dementia? A decision analysis
    Shalini L Kulasingam
    Department of Obstetrics and Gynecology, Duke University Medical Center, Durham NC, USA
    Value Health 6:542-50. 2003
    ..Functional neuroimaging, including positron emission tomography (PET), has been proposed for use in diagnosing Alzheimer's disease-related dementia (AD)...
  70. ncbi Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE--a randomized controlled study
    Cris A Slentz
    Divisions of Cardiology, Geriatric Medicine, and General Internal Medicine, Department of Medicine, Duke Center for Living, Center for Health Policy Research, Durham, NC 27710, USA
    Arch Intern Med 164:31-9. 2004
    ..Obesity is a major health problem due, in part, to physical inactivity. The amount of activity needed to prevent weight gain is unknown...
  71. ncbi Charlson Index comorbidity adjustment for ischemic stroke outcome studies
    Larry B Goldstein
    Durham VA Medical Center, Durham, NC, USA
    Stroke 35:1941-5. 2004
    ..The purpose of the present study was to determine whether outcomes of ischemic stroke patients varied on the basis of the Charlson Index...
  72. ncbi Alzheimer disease: operating characteristics of PET--a meta-analysis
    Meenal B Patwardhan
    Duke Center for Clinical Health Policy Research, 2200 W Main St, Suite 220, Durham, NC 27705, USA
    Radiology 231:73-80. 2004
    ..To assess the operating characteristics of positron emission tomography (PET) by using fluorine 18 fluorodeoxyglucose (FDG) in the diagnosis of Alzheimer disease...
  73. ncbi Utility of the advanced chronic kidney disease patient management tools: case studies
    Meenal B Patwardhan
    Department of Medicine, Duke Center for Clinical Health Policy Research, Duke University Medical Center, Durham NC 27705, USA
    Am J Med Qual 23:105-14. 2008
    ..Our results suggest that systematically created, multifaceted, and customizable tools can promote guideline conformance...
  74. ncbi Burden of illness and satisfaction with care among patients with headache seen in a primary care setting
    Linda H Harpole
    Duke University Medical Center, Department of Medicine, Durham, NC 27705, USA
    Headache 45:1048-55. 2005
    ..Future efforts should be directed at developing and evaluating methods for effectively improving headache management...
  75. ncbi Making evidence-based practice improvement more than a comforting sentiment
    David B Matchar
    Am J Med 115:407-9. 2003
  76. ncbi Development, validation, and application of a microsimulation model to predict stroke and mortality in medically managed asymptomatic patients with significant carotid artery stenosis
    HARRY J SMOLEN
    Medical Decision Modeling Inc, Indianapolis, IN, USA
    Value Health 10:489-97. 2007
    ..To develop a model to predict stroke-free survival and mortality over a multiyear time frame for a trial-excluded population of medically managed asymptomatic patients with significant carotid artery stenosis...
  77. ncbi Microbiology of ventilator-associated pneumonia compared with that of hospital-acquired pneumonia
    David J Weber
    Department of Hospital Epidemiology, University of North Carolina Health Care System, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA
    Infect Control Hosp Epidemiol 28:825-31. 2007
    ..This evaluation assessed whether the currently recommended empirical therapy is appropriate for both ventilator-associated pneumonia (VAP) and HAP by evaluating the infecting flora...
  78. ncbi Changing physician knowledge, attitudes, and beliefs about migraine: evaluation of a new educational intervention
    Meenal B Patwardhan
    Center for Clinical Health Policy Research, Duke University Medical Center, Durham, NC 27705, USA
    Headache 46:732-41. 2006
    ..The program could be strengthened to improve emphasis in some areas where posttest scores showed no improvement...