Jed Rose

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs
    George R Uhl
    Molecular Neurobiology Branch, NIH IRP, NIDA, Baltimore, Maryland 21224, USA
    BMC Genet 8:10. 2007
  2. ncbi request reprint Extinguishing the rewarding value of smoke cues: pharmacological and behavioral treatments
    Jed E Rose
    VA Medical Center, and Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
    Nicotine Tob Res 6:523-32. 2004
  3. ncbi request reprint Effects of low nicotine content cigarettes on smoke intake
    Jed Rose
    VA Medical Center and Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
    Nicotine Tob Res 6:309-19. 2004
  4. ncbi request reprint Mecamylamine acutely increases human intravenous nicotine self-administration
    Jed E Rose
    VA Medical Center, Durham, NC 27705, USA
    Pharmacol Biochem Behav 76:307-13. 2003
  5. ncbi request reprint Pharmacologic and sensorimotor components of satiation in cigarette smoking
    Jed E Rose
    VA Medical Center, Durham, NC 27705, USA
    Pharmacol Biochem Behav 76:243-50. 2003
  6. doi request reprint Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats
    Edward D Levin
    Department of Psychiatry and Behavioral Sciences, Box 104790, Duke University Medical Center, Durham, NC 27710, USA
    Eur J Pharmacol 650:256-60. 2011
  7. ncbi request reprint Individual differences in nicotine dependence, withdrawal symptoms, and sex predict transient fMRI-BOLD responses to smoking cues
    Francis J McClernon
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27708, USA
    Neuropsychopharmacology 33:2148-57. 2008
  8. ncbi request reprint Denicotinized cigarettes: a new tool to combat cigarette addiction?
    Jed E Rose
    Addiction 102:181-2. 2007
  9. ncbi request reprint Regional brain activity correlates of nicotine dependence
    Jed E Rose
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
    Neuropsychopharmacology 32:2441-52. 2007
  10. pmc Increases in impulsivity following smoking abstinence are related to baseline nicotine intake and boredom susceptibility
    Jasmine Pettiford
    Duke University Medical Center, Durham, NC 27707, United States
    Addict Behav 32:2351-7. 2007

Detail Information

Publications34

  1. pmc Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs
    George R Uhl
    Molecular Neurobiology Branch, NIH IRP, NIDA, Baltimore, Maryland 21224, USA
    BMC Genet 8:10. 2007
    ....
  2. ncbi request reprint Extinguishing the rewarding value of smoke cues: pharmacological and behavioral treatments
    Jed E Rose
    VA Medical Center, and Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
    Nicotine Tob Res 6:523-32. 2004
    ....
  3. ncbi request reprint Effects of low nicotine content cigarettes on smoke intake
    Jed Rose
    VA Medical Center and Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
    Nicotine Tob Res 6:309-19. 2004
    ..Further studies should determine whether similar results are obtained in naturalistic environments...
  4. ncbi request reprint Mecamylamine acutely increases human intravenous nicotine self-administration
    Jed E Rose
    VA Medical Center, Durham, NC 27705, USA
    Pharmacol Biochem Behav 76:307-13. 2003
    ..Thus, animal models of nicotine dependence may need to be employed in conjunction with self-administration procedures in order to duplicate the effects of mecamylamine observed in studies of human smokers...
  5. ncbi request reprint Pharmacologic and sensorimotor components of satiation in cigarette smoking
    Jed E Rose
    VA Medical Center, Durham, NC 27705, USA
    Pharmacol Biochem Behav 76:243-50. 2003
    ..v. nicotine and denicotinized smoke approximated the effects of the usual brand. The results of this study underscore the importance of both sensorimotor aspects of smoking and the pharmacologic effects of nicotine in tobacco dependence...
  6. doi request reprint Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats
    Edward D Levin
    Department of Psychiatry and Behavioral Sciences, Box 104790, Duke University Medical Center, Durham, NC 27710, USA
    Eur J Pharmacol 650:256-60. 2011
    ..H(1) antagonists may be a promising avenue to explore for new treatments to aid smoking cessation...
  7. ncbi request reprint Individual differences in nicotine dependence, withdrawal symptoms, and sex predict transient fMRI-BOLD responses to smoking cues
    Francis J McClernon
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27708, USA
    Neuropsychopharmacology 33:2148-57. 2008
    ..These findings provide further evidence that reactivity to conditioned drug cues is multiply determined and suggest that smoking cessation treatments designed to reduce cue reactivity focus on each of these variables...
  8. ncbi request reprint Denicotinized cigarettes: a new tool to combat cigarette addiction?
    Jed E Rose
    Addiction 102:181-2. 2007
  9. ncbi request reprint Regional brain activity correlates of nicotine dependence
    Jed E Rose
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
    Neuropsychopharmacology 32:2441-52. 2007
    ..The results also highlight the likely role of thalamic gating processes as well as striatal reward and corticolimbic regulatory pathways in the maintenance of cigarette addiction...
  10. pmc Increases in impulsivity following smoking abstinence are related to baseline nicotine intake and boredom susceptibility
    Jasmine Pettiford
    Duke University Medical Center, Durham, NC 27707, United States
    Addict Behav 32:2351-7. 2007
    ..These results suggest that smoking abstinence significantly increases errors of response inhibition and that the magnitude of this increase is related to trait impulsivity and nicotine intake variables...
  11. doi request reprint A randomized trial of nicotine replacement therapy in combination with reduced-nicotine cigarettes for smoking cessation
    Karen M Becker
    Becker and Associates Consulting, Inc, Washington, DC, USA
    Nicotine Tob Res 10:1139-48. 2008
    ..4% vs. 21.9%). No serious adverse events were attributable to the investigational product. Quest plus NRT offers promise as a new smoking cessation treatment...
  12. ncbi request reprint The effects of foods, beverages, and other factors on cigarette palatability
    F Joseph McClernon
    Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27708, USA
    Nicotine Tob Res 9:505-10. 2007
    ..Clinical implications and directions for future research are discussed...
  13. ncbi request reprint Selectively reduced responses to smoking cues in amygdala following extinction-based smoking cessation: results of a preliminary functional magnetic resonance imaging study
    F Joseph McClernon
    Duke University Medical Center, NC 27708, USA
    Addict Biol 12:503-12. 2007
    ....
  14. pmc Molecular genetics of successful smoking cessation: convergent genome-wide association study results
    George R Uhl
    Molecular Neurobiology Research Branch, National Institutes of Health Intramural Research Program, National Institute on Drug Abuse, 333 Cassell Dr, Ste 3510, Baltimore, MD 21224, USA
    Arch Gen Psychiatry 65:683-93. 2008
    ..Smoking remains a major public health problem. Twin studies indicate that the ability to quit smoking is substantially heritable, with genetics that overlap modestly with the genetics of vulnerability to dependence on addictive substances...
  15. ncbi request reprint Effects of smoking abstinence on adult smokers with and without attention deficit hyperactivity disorder: results of a preliminary study
    F Joseph McClernon
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 2701, Durham, NC, 27708, USA
    Psychopharmacology (Berl) 197:95-105. 2008
    ..Individuals with attention deficit hyperactivity disorder (ADHD) smoke at higher rates than the general population; however, little is known about the mechanisms underlying this comorbidity...
  16. ncbi request reprint DRD4 VNTR polymorphism is associated with transient fMRI-BOLD responses to smoking cues
    F Joseph McClernon
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27708, USA
    Psychopharmacology (Berl) 194:433-41. 2007
    ..A dopamine receptor 4 variable number tandem repeat (DRD4 VNTR) polymorphism has been related to reactivity to smoking cues among smokers, but the effect of this genetic variation on brain responses to smoking cues has not been evaluated...
  17. ncbi request reprint Multiple brain pathways and receptors underlying tobacco addiction
    Jed E Rose
    Center for Nicotine and Smoking Cessation Research, Duke University Medical Center, Durham, NC 27705, USA
    Biochem Pharmacol 74:1263-70. 2007
    ..Tobacco addiction may thus be seen as a complex neuropsychopharmacological disorder; further progress in smoking cessation treatment may require that we address the multiple molecular and brain components of this addiction...
  18. ncbi request reprint Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial
    F Joseph McClernon
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
    Psychopharmacology (Berl) 189:125-33. 2006
    ..Despite established links between nicotine dependence and depression, little research has examined the effects of nicotine on depression symptoms...
  19. ncbi request reprint Precessation treatment with nicotine skin patch facilitates smoking cessation
    Jed E Rose
    Nicotine Research Program, VA Medical Center and Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
    Nicotine Tob Res 8:89-101. 2006
    ....
  20. ncbi request reprint Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol
    Ola Blomqvist
    Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030 2103, USA
    Alcohol Clin Exp Res 26:326-31. 2002
    ..This study was conducted to test the hypothesis that, during the ascending limb of the blood alcohol concentration curve, mecamylamine would reduce the stimulating and pleasurable effects of an intoxicating dose of alcohol in humans...
  21. ncbi request reprint Adolescent-onset nicotine self-administration modeled in female rats
    Edward D Levin
    Neurobehavioral Research Laboratory, Department of Psychiatry, Duke University Medical Center, 341 Bell Building, Box 3412, Durham, NC 27710, USA
    Psychopharmacology (Berl) 169:141-9. 2003
    ..Although the great majority of tobacco addiction begins during adolescence, little is known about differential nicotine effects in adolescents versus adults...
  22. ncbi request reprint Psychopharmacological interactions between nicotine and ethanol
    Jed E Rose
    VA Medical Center and Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
    Nicotine Tob Res 6:133-44. 2004
    ..These results highlight the potent interaction between ethanol and nicotinic systems, and suggest that ethanol can potentiate the rewarding effects of nicotine as well as offset some of the effects of a nicotinic antagonist...
  23. ncbi request reprint The effects of controlled deep breathing on smoking withdrawal symptoms in dependent smokers
    F Joseph McClernon
    Department of Psychiatry, Nicotine Research Program, Duke University and Durham VA Medical Centers, 2200 W Main St, B 150, Durham, NC 27705, USA
    Addict Behav 29:765-72. 2004
    ..The results of this preliminary study suggest that controlled deep breathing may be useful for relieving symptoms of smoking withdrawal...
  24. ncbi request reprint Reliabilities and intercorrelations of reported and objective measures of smoking in patients with schizophrenia
    Yen Kuang Yang
    National Cheng Kung University, 138 Sheng Li Road, Tainan 704, Taiwan
    Schizophr Res 60:9-12. 2003
    ..All measures demonstrated good test-retest reliability. Objective measures of smoking were consistently intercorrelated and should be the preferred outcome measures in studies testing strategies to reduce smoking...
  25. ncbi request reprint Mecamylamine moderates cue-induced emotional responses in smokers
    F Joseph McClernon
    Tobacco Neuroscience Research Laboratory, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 3516, Durham, NC 27710, United States
    Addict Behav 30:741-53. 2005
    ..A similar trend was observed for negative affect. These results suggest that mecamylamine can moderate smoking cue-induced emotional responses in smokers...
  26. ncbi request reprint Potentiation of nicotine reward by alcohol
    Jed E Rose
    Nicotine Research Program, Duke University and VA Medical Center, Durham, North Carolina 27705, USA
    Alcohol Clin Exp Res 26:1930-1. 2002
  27. pmc Abstinence-induced changes in self-report craving correlate with event-related FMRI responses to smoking cues
    F Joseph McClernon
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27708, USA
    Neuropsychopharmacology 30:1940-7. 2005
    ....
  28. ncbi request reprint Immediate antecedents of cigarette smoking in smokers with and without posttraumatic stress disorder: a preliminary study
    Jean C Beckham
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27705, USA
    Exp Clin Psychopharmacol 13:219-28. 2005
    ..These results are consistent with previous ambulatory findings regarding mood in smokers but also underscore that, in certain populations, mood and symptom variables may be significantly associated with ad lib smoking...
  29. ncbi request reprint Nicotine and nonnicotine factors in cigarette addiction
    Jed E Rose
    Center for Nicotine and Smoking Cessation Research, Duke University Medical Center, 2424 Erwin Road, Suite 201, Durham, NC 27705, USA
    Psychopharmacology (Berl) 184:274-85. 2006
    ..These include constituents that provide reinforcing sensory stimulation, components that minimize excessive irritation from inhaled nicotine and other pharmacologically active compounds in cigarette smoke...
  30. ncbi request reprint Neuroactive steroids, negative affect, and nicotine dependence severity in male smokers
    Christine E Marx
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, and Durham Veterans Affairs Medical Center, Durham, NC 27710, USA
    Psychopharmacology (Berl) 186:462-72. 2006
    ..These molecules may be relevant to tobacco addiction and affective symptoms...
  31. ncbi request reprint PET studies of the influences of nicotine on neural systems in cigarette smokers
    Jed E Rose
    Veterans Affairs Medical Center, Durham, NC, USA
    Am J Psychiatry 160:323-33. 2003
    ..The effects of acute nicotine administration and smoking on brain function were investigated in two studies, with the primary goal of identifying neural systems that mediate these effects...
  32. ncbi request reprint The effects of trauma recall on smoking topography in posttraumatic stress disorder and non-posttraumatic stress disorder trauma survivors
    F Joseph McClernon
    Duke University Medical Center, Durham, NC, USA
    Addict Behav 30:247-57. 2005
    ....
  33. ncbi request reprint Ethics of tobacco company funding
    Jed E Rose
    Science 308:632. 2005
  34. ncbi request reprint Guidelines on nicotine dose selection for in vivo research
    Shannon G Matta
    Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 874 Union Avenue, Crowe 115, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 190:269-319. 2007
    ..In many cases, such discrepancies could be attributed to the complex variables comprising species-specific in vivo responses to acute or chronic nicotine exposure...