James Rochon

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Design and conduct of the CALERIE study: comprehensive assessment of the long-term effects of reducing intake of energy
    James Rochon
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    J Gerontol A Biol Sci Med Sci 66:97-108. 2011
  2. ncbi request reprint Using a serial marker to predict a repeated measures outcome in a cohort design--results of a simulation study
    James Rochon
    Department of Biostatistics and Bioinformatics and Duke Clinical Research Institute, Duke University, Durham, North Carolina 27715, USA
    J Biopharm Stat 14:817-33. 2004
  3. ncbi request reprint Using a serial marker to predict a repeated measures outcome in a cohort study
    James Rochon
    Department of Biostatistics and Bioinformatics and the Duke Clinical Research Institute, Duke University, Durham, North Carolina 27715, USA
    J Biopharm Stat 13:283-300. 2003
  4. ncbi request reprint Common design elements of the Girls health Enrichment Multi-site Studies (GEMS)
    James Rochon
    Biostatistics Center, George Washington University, Rockville, Maryland, USA
    Ethn Dis 13:S6-14. 2003
  5. pmc Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury
    James Rochon
    Duke Clinical Research Institute, Durham, NC 27713, USA
    Hepatology 48:1175-83. 2008
  6. pmc The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain
    Lillian F Lien
    Department of Medicine, Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    OMICS 13:21-35. 2009
  7. pmc A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    Christopher B Newgard
    Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    Cell Metab 9:311-26. 2009
  8. pmc Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs
    Thomas J Urban
    Center for Human Genome Variation, Duke University, Durham, NC, USA
    Pharmacogenet Genomics 22:784-95. 2012
  9. pmc Development of adherence metrics for caloric restriction interventions
    Carl Pieper
    Department of Biostatistics and Bioinformatics, Duke University Medical Center, Center on Aging, DUMC, Durham, NC, USA
    Clin Trials 8:155-64. 2011
  10. ncbi request reprint Pain, stiffness, and fatigue in juvenile polyarticular arthritis: contemporaneous stressful events and mood as predictors
    Laura E Schanberg
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Arthritis Rheum 52:1196-204. 2005

Research Grants

  1. WEIGHT GAIN IN AFRICAN-AMERICAN GIRLS
    James Rochon; Fiscal Year: 2002
  2. Coordinating Center for CALERIE
    James Rochon; Fiscal Year: 2007
  3. Coordinating Center for Hepatotoxicity Network
    James Rochon; Fiscal Year: 2007

Detail Information

Publications26

  1. pmc Design and conduct of the CALERIE study: comprehensive assessment of the long-term effects of reducing intake of energy
    James Rochon
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    J Gerontol A Biol Sci Med Sci 66:97-108. 2011
    ..This article presents the design and implementation of this study...
  2. ncbi request reprint Using a serial marker to predict a repeated measures outcome in a cohort design--results of a simulation study
    James Rochon
    Department of Biostatistics and Bioinformatics and Duke Clinical Research Institute, Duke University, Durham, North Carolina 27715, USA
    J Biopharm Stat 14:817-33. 2004
    ..The ability to predicting the primary outcome corresponding to a known marker profile of specific interest was examined...
  3. ncbi request reprint Using a serial marker to predict a repeated measures outcome in a cohort study
    James Rochon
    Department of Biostatistics and Bioinformatics and the Duke Clinical Research Institute, Duke University, Durham, North Carolina 27715, USA
    J Biopharm Stat 13:283-300. 2003
    ..Hypotheses of interest are described and procedures for testing them are elaborated. The Diabetes Control and Complications Trial is used to illustrate the procedures...
  4. ncbi request reprint Common design elements of the Girls health Enrichment Multi-site Studies (GEMS)
    James Rochon
    Biostatistics Center, George Washington University, Rockville, Maryland, USA
    Ethn Dis 13:S6-14. 2003
    ..This report presents the basic study design, a brief overview of the interventions, the measurements taken and their rationale, and procedures both for compiling the collaborative database, and performing site-specific analyses...
  5. pmc Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury
    James Rochon
    Duke Clinical Research Institute, Durham, NC 27713, USA
    Hepatology 48:1175-83. 2008
    ..54 (upper 95% confidence limit = 0.77); the interrater reliability was 0.45 (upper 95% confidence limit = 0.58). Categorizing the RUCAM to a five-category scale improved these reliabilities but only marginally...
  6. pmc The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain
    Lillian F Lien
    Department of Medicine, Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    OMICS 13:21-35. 2009
    ..These findings provide evidence for sustained benefits of weight loss in obese humans and insights into mechanisms...
  7. pmc A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    Christopher B Newgard
    Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    Cell Metab 9:311-26. 2009
    ..Our findings show that in the context of a dietary pattern that includes high fat consumption, BCAA contributes to development of obesity-associated insulin resistance...
  8. pmc Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs
    Thomas J Urban
    Center for Human Genome Variation, Duke University, Durham, NC, USA
    Pharmacogenet Genomics 22:784-95. 2012
    ..We carried out a genome-wide association study of 783 individuals of European ancestry who experienced DILI due to more than 200 implicated drugs...
  9. pmc Development of adherence metrics for caloric restriction interventions
    Carl Pieper
    Department of Biostatistics and Bioinformatics, Duke University Medical Center, Center on Aging, DUMC, Durham, NC, USA
    Clin Trials 8:155-64. 2011
    ..These normograms can then be used by counselors to help the participant adhere to their caloric target...
  10. ncbi request reprint Pain, stiffness, and fatigue in juvenile polyarticular arthritis: contemporaneous stressful events and mood as predictors
    Laura E Schanberg
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Arthritis Rheum 52:1196-204. 2005
    ..To analyze patterns of stress, mood, disease symptoms, and activity reduction in children with polyarticular arthritis, using a prospective daily diary method...
  11. pmc TCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention program
    Jeanne M McCaffery
    The Biostatistics Center, The George Washington University, Rockville, Maryland, United States of America
    PLoS ONE 6:e21518. 2011
    ..Here we sought to test whether these effects were apparent in high-risk individuals and modify treatment responses...
  12. ncbi request reprint The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design
    Andrea M Haqq
    Sarah W Stedman Nutrition and Metabolism Center, Duke University, Durham, NC 27705, USA
    Contemp Clin Trials 26:616-25. 2005
    ..Results from this study will expand our knowledge of the biology of obesity and weight regulation and may lead to targeted strategies for its treatment and control...
  13. ncbi request reprint Early sexual maturation, body composition, and obesity in African-American girls
    John H Himes
    Division of Epidemiology, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
    Obes Res 12:64S-72S. 2004
    ..To describe associations between sexual maturation and body composition in a sample of African-American girls who were participants in phase 1 pilot interventions of the Girls Health Enrichment Multisite Studies...
  14. ncbi request reprint Physical activity self-report and accelerometry measures from the Girls health Enrichment Multi-site Studies
    Margarita S Treuth
    Center for Human Nutrition, Johns Hopkins University, Baltimore, MD 21205, USA
    Prev Med 38:S43-9. 2004
    ..Valid and reliable physical activity checklists are needed to assess effectiveness of interventions. This study tested the validity and reliability of the Girls health Enrichment Multi-site Studies (GEMS) Activity Questionnaire...
  15. ncbi request reprint Measurement characteristics of diet-related psychosocial questionnaires among African-American parents and their 8- to 10-year-old daughters: results from the Girls' health Enrichment Multi-site Studies
    Karen W Cullen
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Prev Med 38:S34-42. 2004
    ..This paper presents the reliability and validity of several diet-related psychosocial questionnaires...
  16. ncbi request reprint The Fun, Food, and Fitness Project (FFFP): the Baylor GEMS pilot study
    Tom Baranowski
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030 2600, USA
    Ethn Dis 13:S30-9. 2003
    ..The Girls health Enrichment Multisite Studies (GEMS) Fun, Food, and Fitness Project (FFFP) was designed to prevent obesity among 8-year-old African-American girls...
  17. ncbi request reprint Child- and parent-targeted interventions: the Memphis GEMS pilot study
    Bettina M Beech
    University of Memphis, Center for Community Health, Tennessee 38119, USA
    Ethn Dis 13:S40-53. 2003
    ..To assess the feasibility, acceptability, and outcomes of 2 versions of a culturally relevant, family-based intervention to prevent excess weight gain in pre-adolescent African-American girls...
  18. ncbi request reprint An after-school obesity prevention program for African-American girls: the Minnesota GEMS pilot study
    Mary Story
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Ethn Dis 13:S54-64. 2003
    ..This study was part of the GEMS project, created to test interventions designed to reduce excess weight gain in African-American girls...
  19. ncbi request reprint Dance and reducing television viewing to prevent weight gain in African-American girls: the Stanford GEMS pilot study
    Thomas N Robinson
    Division of General Pediatrics, Department of Pediatrics, The Stanford Center for Research in Disease Prevention, Palo Alto, CA 94304, USA
    Ethn Dis 13:S65-77. 2003
    ..To test the feasibility, acceptability, and potential efficacy of after-school dance classes and a family-based intervention to reduce television viewing, thereby reducing weight gain, among African-American girls...
  20. ncbi request reprint Recruitment of African-American pre-adolescent girls into an obesity prevention trial: the GEMS pilot studies
    Mary Story
    University of Minnesota, Division of Epidemiology, Minneapolis, Minnesota 55454, USA
    Ethn Dis 13:S78-87. 2003
    ..The objective of this report is to describe the methods used to recruit 8- to 10-year-old African-American girls into four 12-week randomized controlled pilot studies on obesity prevention...
  21. ncbi request reprint Evaluation of quality control procedures for 24-h dietary recalls: results from the Girls Health Enrichment Multisite Studies
    Karen W Cullen
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Prev Med 38:S14-23. 2004
    ..Quality control methods are key components of dietary assessment, but have rarely been evaluated...
  22. ncbi request reprint Validity and reliability of a behavior-based food coding system for measuring fruit, 100% fruit juice, vegetable, and sweetened beverage consumption: results from the Girls Health Enrichment Multisite Studies
    Karen W Cullen
    Department of Pediatrics, Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Prev Med 38:S24-33. 2004
    ..This paper presents the rationale, reliability, and validity of a behavior-based food coding system for measuring fruit (F), juice (J), vegetable (V), sweetened beverage, and water consumption in children...
  23. pmc Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program
    Allan F Moore
    Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes 57:2503-10. 2008
    ....
  24. ncbi request reprint Mixed-effect models to assess consistency and reliability across multiple evaluations
    Tzu Cheg Kao
    Division of Epidemiology and Biostatistics, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    J Biopharm Stat 13:539-48. 2003
    ..The SAS program code for performing the statistical analysis is provided. The models can be generalized to account for more design factors and other applicable covariates...
  25. ncbi request reprint Validity and reliability of activity measures in African-American girls for GEMS
    Margarita S Treuth
    Center for Human Nutrition, Johns Hopkins University, Baltimore, MD 21205, USA
    Med Sci Sports Exerc 35:532-9. 2003
    ..To determine the reliability and validity of physical activity monitors and self-report instruments suitable for young African-American girls...
  26. ncbi request reprint Interaction and intervention modeling: predicting and extrapolating the impact of multiple interventions
    Richard Riegelman
    Department of Epidemiology and Biostatistics, The George Washington University School of Public Health and Health Services, Washington, DC 20037, USA
    Ann Epidemiol 12:151-6. 2002
    ..The aim is to develop methods that will be useful for modeling and comparing intervention strategies using existing data and standard statistical methods...

Research Grants5

  1. WEIGHT GAIN IN AFRICAN-AMERICAN GIRLS
    James Rochon; Fiscal Year: 2002
    ..3) Statistical Analysis: We will provide statistical leadership in the design of the study, and perform interim and final analyses in an expeditious and timely manner. ..
  2. Coordinating Center for CALERIE
    James Rochon; Fiscal Year: 2007
    ..3) Statistical Analysis: We will provide statistical leadership in the design of these studies; and perform interim and final analyses in an expeditious and timely manner. ..
  3. Coordinating Center for Hepatotoxicity Network
    James Rochon; Fiscal Year: 2007
    ..4) Statistical Analysis: we will provide statistical leadership in the design of these studies, and perform statistical analyses in an expeditious and timely manner. ..