Research Topics
| Srinevas K ReddySummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
Simultaneous resections of colorectal cancer and synchronous liver metastases: a multi-institutional analysisSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
Ann Surg Oncol 14:3481-91. 2007..This multi-institutional retrospective study compared postoperative outcomes after simultaneous and staged colorectal and hepatic resections...
Synchronous colorectal liver metastases: is it time to reconsider traditional paradigms of management?Srinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC, USA
Ann Surg Oncol 16:2395-410. 2009..This review describes the rationale for this treatment approach and the recent developments suggesting that this management paradigm should be reconsidered...- Multiagent chemotherapy for isolated colorectal liver metastases: a single-centered retrospective studySrinevas K Reddy
Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
J Gastrointest Surg 13:74-84. 2009..The objective of this retrospective study was to determine the effect of multiagent chemotherapy on long-term survival after resection of CLM... - Extended hepatic resection for gallbladder cancerSrinevas K Reddy
Division of General Surgery, Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
Am J Surg 194:355-61. 2007.... - Resection of hepatocellular adenoma in patients with glycogen storage disease type IaSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
J Hepatol 47:658-63. 2007..The objective of this retrospective study is to assess the safety and effectiveness of HCA resection in GSD Ia patients... - Timing of multimodality therapy for resectable synchronous colorectal liver metastases: a retrospective multi-institutional analysisSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
Ann Surg Oncol 16:1809-19. 2009..However, prospective randomized trials are needed to determine the optimal timing of chemotherapy... - Surgical management of gallbladder cancerSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
Surg Oncol Clin N Am 18:307-24, ix. 2009..Large retrospective and underpowered prospective studies have suggested benefit to adjuvant chemotherapy or radiotherapy; however, these results need to be confirmed with large prospective randomized trials... - Neuroendocrine liver metastasesSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
Surg Clin North Am 90:853-61. 2010.... - Hepatic parenchymal transection with vascular staplers: a comparative analysis with the crush-clamp techniqueSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC, USA
Am J Surg 196:760-7. 2008..This retrospective study compares the safety and efficacy of hepatic parenchymal transection using vascular staplers (VS) and the crush-clamp (CC) technique... - Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastasesSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Am Coll Surg 206:96-106. 2008..The objective of this retrospective study was to determine if addition of bevacizumab to iri/oxal preoperative chemotherapy increases morbidity after hepatic resection... - Comparison of outcomes and the use of multimodality therapy in young and elderly people undergoing surgical resection of pancreatic cancerAndrew S Barbas
Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
J Am Geriatr Soc 60:344-50. 2012..To compare outcomes and the use of multimodality therapy in young and elderly people with pancreatic cancer undergoing surgical resection... - Surgery versus intra-arterial therapy for neuroendocrine liver metastasis: a multicenter international analysisSkye C Mayo
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Ann Surg Oncol 18:3657-65. 2011..We sought to examine the relative efficacy of surgical management versus intra-arterial therapy (IAT) for NELM and determine factors predictive of survival... 
Hepatic resection for metastatic gastrointestinal stromal tumors in the tyrosine kinase inhibitor eraRyan S Turley
Department of Surgery, Duke University Medical Center, Durham, NC 27110, USA
Cancer 118:3571-8. 2012..The objective of this study was to determine whether combination therapy for hepatic GIST metastases is associated with improved overall survival compared with reported outcomes from surgery or TKI therapy alone...- Simultaneous diaphragm and liver resection: a propensity-matched analysis of postoperative morbidityGeorge Z Li
School of Medicine, Duke University Medical Center, Durham, NC 27710, USA
J Am Coll Surg 216:402-11. 2013.... - Incidence of benign disease in patients that underwent resection for presumed pancreatic cancer diagnosed by endoscopic ultrasonography (EUS) and fine-needle aspiration (FNA)Sebastian G de la Fuente
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Gastrointest Surg 14:1139-42. 2010..In this study, we investigated the incidence of benign disease in patients that underwent resection for presumed pancreatic cancer diagnosed by EUS and EUS-guided FNA... - Impact of simultaneous diaphragm resection during hepatectomy for treatment of metastatic colorectal cancerGeorge Z Li
School of Medicine, Duke University Medical Center, Durham, NC 27710, USA
J Gastrointest Surg 16:1508-15. 2012..The purpose of this study is to determine whether diaphragm resection during partial hepatectomy for metastatic colorectal cancer influences short-term perioperative outcomes and overall survival... - Liver transplantation for glycogen storage disease type IaSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC, USA
J Hepatol 51:483-90. 2009..The objective of this retrospective study is to assess outcomes after liver transplantation (LT) for GSD Ia where the principal indication for transplantation was prevention of HCC... - Resection of noncolorectal nonneuroendocrine liver metastases: a comparative analysisSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC 27713, USA
J Am Coll Surg 204:372-82. 2007..Although established for metastatic colorectal (CR) and neuroendocrine (NE) malignancies, the role of partial hepatectomy in management of metastases from other primaries (NCRNE) is not well-defined... - RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicinJing Mi
Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
Mol Ther 16:66-73. 2008..These studies provide important insights into the mechanisms of Dox-induced chemoresistance, and they demonstrate a novel, effective, and clinically practical strategy for interfering with these processes... - Liver-directed surgery for metastatic squamous cell carcinoma to the liver: results of a multi-center analysisTimothy M Pawlik
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
Ann Surg Oncol 14:2807-16. 2007..The role of hepatic resection for metastatic squamous cell carcinoma (SCC) remains unknown. The current study evaluates the role of hepatic resection in patients with metastatic SCC to the liver... - Major liver resection in elderly patients: a multi-institutional analysisSrinevas K Reddy
Department of Surgery, Duke University Medical Center, Durham, NC, USA
J Am Coll Surg 212:787-95. 2011..The objective of this study was to assess the influence of age on postoperative outcomes after major hepatectomy among a contemporary cohort from 2 high volume centers... - Surgical management of hepatic neuroendocrine tumor metastasis: results from an international multi-institutional analysisSkye C Mayo
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Ann Surg Oncol 17:3129-36. 2010..We sought to define the efficacy of the surgical management of NELM in a large multicenter international cohort of patients... - Laparoscopic liver resectionSrinevas K Reddy
Department of Surgery, UPMC Liver Cancer Center, Starzl Transplant Institute, University of Pittsburgh, 3459 Fifth Avenue, UPMC Montefiore 7 South, Pittsburgh, PA 15213, USA
World J Surg 35:1478-86. 2011.... - Defining criteria for selective operative management of pancreatic cystic lesions: does size really matter?Eugene P Ceppa
Department of Surgery, Duke University Medical Center, P O Box 3247, Durham, NC 27710, USA
J Gastrointest Surg 14:236-44. 2010..The objective of this study was to evaluate risk factors for malignancy in a large series of patients undergoing resection of suspected pancreatic cystic neoplasms... - Venous thromboembolism after hepatic resection: analysis of 5,706 patientsRyan S Turley
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Gastrointest Surg 16:1705-14. 2012..The objective of our analysis was to identify perioperative predictors of postoperative VTE in patients undergoing resection... - Extended resection for pancreatic adenocarcinomaSrinevas K Reddy
Duke University Medical Center, Box 3247, Durham, North Carolina 27710, USA
Oncologist 12:654-63. 2007..The disappointing experience with extended resections underscores the need for better adjuvant systemic strategies and the interdisciplinary care of patients with pancreatic adenocarcinoma... - Prevalence of nonalcoholic steatohepatitis among patients with resectable intrahepatic cholangiocarcinomaSrinevas K Reddy
Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA
J Gastrointest Surg 17:748-55. 2013..The objective of this report was to determine the prevalence of underlying nonalcoholic steatohepatitis in resectable intrahepatic cholangiocarcinoma... - NF-kappaB inhibition by an adenovirus expressed aptamer sensitizes TNFalpha-induced apoptosisJing Mi
Department of Surgery, Duke University Medical Center, Box 2633, MSRB Building, Durham, NC 27710, USA
Biochem Biophys Res Commun 359:475-80. 2007..RNA aptamer inhibition of NF-kappaB offers exciting opportunities for sensitizing inflammatory and tumor cells to TNFalpha-induced apoptosis... - Hepatic insufficiency and mortality in 1,059 noncirrhotic patients undergoing major hepatectomyJohn T Mullen
Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
J Am Coll Surg 204:854-62; discussion 862-4. 2007..No standard definition of PHI has been established, but one is essential for meaningful comparison of outcomes data across studies...