Research Topics
| L R ProsnitzSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
The treatment of high-grade soft tissue sarcomas with preoperative thermoradiotherapyL R Prosnitz
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Radiat Oncol Biol Phys 45:941-9. 1999..To explore the use of a novel program of preoperative radiation and hyperthermia in the management of high-grade soft tissue sarcomas (STS)...- Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostateM S Anscher
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Radiat Oncol Biol Phys 37:1059-65. 1997..To determine the safety and efficacy of combined external beam irradiation and external regional hyperthermia in the treatment of adenocarcinoma of the prostate... - A phase II trial testing the thermal dose parameter CEM43 degrees T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapyP D Maguire
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Hyperthermia 17:283-90. 2001..Possible explanations for this outcome are discussed... - Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcomaD M Brizel
Department of Radiation Oncology, Duke University Comprehensive Cancer Center, Durham, North Carolina, 27710, USA
Cancer Res 56:941-3. 1996..Median pO2 was 7.5 mm Hg for metastasizing tumors versus 20 mm Hg for nonmetastasizing tumors (P=0.03). Potential mechanisms and implications for clinical trial design are discussed... - Prospective assessment of quality of life in ovarian cancer patients receiving whole abdomen hyperthermia and liposomal doxorubicinC A Hahn
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Hyperthermia 21:349-57. 2005..Prospective assessment of quality of life (QoL) in patients with refractory, residual or recurrent ovarian cancer receiving whole abdomen hyperthermia and intravenous liposomal doxorubicin chemotherapy... - A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancerM S Anscher
Department of Radiation Oncology, Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, NC 27710, USA
Int J Radiat Oncol Biol Phys 47:719-24. 2000..To determine the feasibility of combining external beam radiotherapy, continuous infusion 5-fluorouracil (5-FU), and external microwave hyperthermia in patients with locally advanced, unresectable, or recurrent adenocarcinoma of the rectum... - A practical and easy method to locate the first three internal mammary lymph node-bearing areasL B Marks
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Radiat Oncol Biol Phys 50:421-5. 2001..To assess the distance from a clinically recognized anatomic landmark to the different costocondral interspaces in female patients to facilitate the design of radiation fields intended to include specific internal mammary nodal areas... - Cardiac perfusion changes in patients treated for breast cancer with radiation therapy and doxorubicin: preliminary resultsP H Hardenbergh
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Radiat Oncol Biol Phys 49:1023-8. 2001..Long-term follow-up is needed to assess whether these perfusion changes are transient or permanent and to determine if these findings are associated with changes in overall cardiac function and clinical outcome... - Impact of consolidation radiotherapy in patients with advanced breast cancer treated with high-dose chemotherapy and autologous bone marrow rescueD L Carter
Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA
J Clin Oncol 17:887-93. 1999..To examine the impact of consolidation radiotherapy (RT) after high-dose chemotherapy with autologous bone marrow rescue (HDC) in patients with advanced breast cancer... - Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neckD M Brizel
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Radiat Oncol Biol Phys 38:285-9. 1997..This study was performed to evaluate the relationship between tumor hypoxia and DFS in patients with squamous carcinoma of the head and neck (SCCHN)... - Ultrasound guided pO2 measurement of breast cancer reoxygenation after neoadjuvant chemotherapy and hyperthermia treatmentZ Vujaskovic
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Int J Hyperthermia 19:498-506. 2003..The results of this preliminary study suggest that the combination of neoadjuvant chemotherapy and hyperthermia improves oxygenation in locally advanced breast tumours that are initially hypoxic... - Is axillary lymph node dissection indicated for early-stage breast cancer? A decision analysisG Parmigiani
Institute of Statistics and Decision Sciences and Center for Clinical Health Policy Research, Duke University, Durham, NC 27708, USA
J Clin Oncol 17:1465-73. 1999..We constructed a decision model to quantify the benefits of ALND for patients eligible for breast-conserving therapy... - Timing and patterns of recurrences and deaths from prostate cancer following adjuvant pelvic radiotherapy for pathologic stage T3/4 adenocarcinoma of the prostateM S Anscher
Department of Radiation Oncology, Virginia Commonwealth University Medical Center, Richmond, VA 23298 0005, USA
Prostate Cancer Prostatic Dis 9:254-60. 2006..Despite its long natural history, death from prostate cancer was the most common cause of mortality in this population with locally advanced tumors, reflecting the need for more effective therapy... 
The impact of radiation therapy in patients with diffuse large B-cell lymphoma with positive post-chemotherapy FDG-PET or gallium-67 scansJ A Dorth
Department of Radiation Oncology, Division of Medical Oncology, Duke University Medical Center, Durham, USA
Ann Oncol 22:405-10. 2011..However, clinical outcomes when consolidation radiation therapy (RT) is administered are less defined...- Phase I/II trial of intravenous Doxil and whole abdomen hyperthermia in patients with refractory ovarian cancerA Alvarez Secord
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, West Virginia University Schools of Pharmacy and Medicine, Morgantown, WV 26506, USA
Int J Hyperthermia 21:333-47. 2005..Liposomal doxorubicin combined with hyperthermia has been shown to increase both liposomal delivery and drug extravasation into tumour xenografts resulting in enhanced cytotoxic effects...