Research Topics
Genomes and GenesSpecies | E L PritchettSummaryAffiliation: Duke University Medical Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Evolution and revolution in drug labeling: regulation of antiarrhythmic drugs by the Food and Drug Administration 1962-1996E L Pritchett
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Pacing Clin Electrophysiol 21:1457-69. 1998..The FDA, the scientific community, and the pharmaceutical industry have all participated in and been affected by this evolution in drug development...
Antiarrhythmic effects of azimilide in atrial fibrillation: efficacy and dose-response. Azimilide Supraventricular Arrhythmia Program 3 (SVA-3) InvestigatorsE L Pritchett
Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
J Am Coll Cardiol 36:794-802. 2000..The purpose of this study was to assess the effectiveness of azimilide, a class III antiarrhythmic drug, in reducing the frequency of symptomatic arrhythmia recurrences in patients with atrial fibrillation, atrial flutter or both...
Bidisomide (SC-40230), a new antiarrhythmic agent: initial study of tolerability and pharmacokineticsR L Page
Department of Medicine, Duke University Medical Center, Durham, NC 27710
Clin Pharmacol Ther 51:371-8. 1992..12, 1.77, and 12.3 hours, respectively. The mean absolute oral bioavailability was 43%...
Observations on the transition from intermittent to permanent atrial fibrillationS M Al-Khatib
Divisions of Clinical Pharmacology and Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 140:142-5. 2000....
Mortality in patients treated with flecainide and encainide for supraventricular arrhythmiasE L Pritchett
Department of Medicine Division of Clinical Pharmacology and Cardiology, Duke University Medical Center, Durham, North Carolina
Am J Cardiol 67:976-80. 1991..6 with a 95% confidence interval of 0.2, 1.7. These descriptive comparisons did not demonstrate any excess mortality when flecainide and encainide were used in patients with supraventricular arrhythmias...
