Research Topics
Species | B L PlassmanSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Publications
Prevalence and clinical correlates of neuropsychiatric symptoms in dementiaDavid C Steffens
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
Am J Alzheimers Dis Other Demen 20:367-73. 2005..Our results may also shed light on mechanisms that underlie neuropsychiatric symptoms...
Prevalence of dementia in the United States: the aging, demographics, and memory studyB L Plassman
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27701, USA
Neuroepidemiology 29:125-32. 2007..To estimate the prevalence of Alzheimer's disease (AD) and other dementias in the USA using a nationally representative sample...- Identification of dementia: agreement among national survey data, medicare claims, and death certificatesTruls Ostbye
Department of Community and Family Medicine, Duke University Center for Health Policy, School of Nursing, Duke University Medical Center, Box 2914 Med Ctr, Durham, NC 27710, USA
Health Serv Res 43:313-26. 2008..To estimate the proportion of seniors with dementia from three independent data sources and their agreement... - Prevalence of cognitive impairment without dementia in the United StatesBrenda L Plassman
Duke University Medical Center, Durham, North Carolina 27701, USA
Ann Intern Med 148:427-34. 2008..Cognitive impairment without dementia is associated with increased risk for disability, increased health care costs, and progression to dementia. There are no population-based prevalence estimates of this condition in the United States... 
Systematic review: factors associated with risk for and possible prevention of cognitive decline in later lifeBrenda L Plassman
Duke University Medical Center, Durham, North Carolina 27701, USA
Ann Intern Med 153:182-93. 2010..Many biological, behavioral, social, and environmental factors may contribute to the delay or prevention of cognitive decline...- Documented head injury in early adulthood and risk of Alzheimer's disease and other dementiasB L Plassman
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
Neurology 55:1158-66. 2000..The association between antecedent head injury and AD is inconsistent... - Incidence of dementia and cognitive impairment, not dementia in the United StatesBrenda L Plassman
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27701, USA
Ann Neurol 70:418-26. 2011..In this paper, we report US national incidence rates for dementia and CIND... - Duke Twins Study of Memory in Aging in the NAS-NRC Twin RegistryBrenda L Plassman
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27701, USA
Twin Res Hum Genet 9:950-7. 2006..We provide an overview of the study's methodology and describe the focus of recent research... - Age effects of coronary artery bypass graft on cognitive status change among elderly male twinsG G Potter
Department of Psychiatry and Behavioral Sciences, Duke University, Program in Epidemiology of Dementia, 905 W Main St, Box 41 Suite 25 D, Durham, NC 27701, USA
Neurology 63:2245-9. 2004..Research regarding long-term cognitive outcome following coronary artery bypass graft (CABG) is inconsistent, which may be due in part to differential genetic and environmental influences within most study samples... - Occupational characteristics and cognitive performance among elderly male twinsG G Potter
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
Neurology 67:1377-82. 2006..To examine the effect of occupational characteristics on cognitive status change in members of the NAS-NRC Twins Registry of World War II veterans... - Vascular risk factors and cognitive decline among elderly male twinsGlen L Xiong
Program in Epidemiology of Dementia, Duke University Medical Center, Durham, NC 27701, USA
Neurology 67:1586-91. 2006..CONCLUSION: Based on this study of twin pairs who share similar genetic and early environmental risks for cardiovascular risk factors, diabetes is associated with greater cognitive decline, particularly among the oldest individuals... - The effect of spousal caregiving and bereavement on depressive symptomsD H Taylor
Duke University Center for Health Policy, Durham, NC 27708, US
Aging Ment Health 12:100-7. 2008..We conclude that caregiving increases depressive symptoms in the caregiver, but does not have a differential effect by gender. Increases in depressive symptoms following bereavement are short-term... - Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whitesGuy G Potter
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
Alzheimers Dement 5:445-53. 2009..This study compared direct testing and informant reports of cognition with clinical diagnoses of cognitive impairment and dementia between African Americans and whites... - The accuracy of Medicare claims as an epidemiological tool: the case of dementia revisitedDonald H Taylor
Center for Health Policy, Sanford Duke School of Public Policy, Duke University, Durham, NC 27708, USA
J Alzheimers Dis 17:807-15. 2009..The use of Medicare claims to identify dementia results in an overstatement of the increase in Medicare costs that are due to dementia... - Prevalence of depression among older Americans: the Aging, Demographics and Memory StudyDavid C Steffens
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Int Psychogeriatr 21:879-88. 2009..The Aging, Demographics and Memory Study (ADAMS) is a population-representative study that included a depression assessment, providing an opportunity to estimate the prevalence of depression in late life in the U.S.A... - Associations of job demands and intelligence with cognitive performance among men in late lifeGuy G Potter
Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC 27701, USA
Neurology 70:1803-8. 2008..To examine the association of job characteristics and intelligence to cognitive status in members of the National Academy of Sciences-National Research Council Twins Registry of World War II veterans... - Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly studyDavid C Steffens
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Am J Geriatr Psychiatry 15:839-49. 2007..The authors hypothesized that change in subcortical gray matter and white matter hyperintensity volumes would be associated with development of dementia, as would presence of an apolipoprotein E (APOE) epsilon 4 allele... - Methodology and preliminary results from the neurocognitive outcomes of depression in the elderly studyDavid C Steffens
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
J Geriatr Psychiatry Neurol 17:202-11. 2004..These results are consistent with prior evidence linking depression and later dementia. Future studies are needed to examine neuroimaging and genetic, clinical, and social predictors of neurocognitive decline in depression... - Head injury in early adulthood and the lifetime risk of depressionTracey Holsinger
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
Arch Gen Psychiatry 59:17-22. 2002..The lifetime risk of depression increased with severity of the head injury. CONCLUSION: The risk of depression remains elevated for decades following head injury and seems to be highest in those who have had a severe head injury... - A twin study of the genetic contribution to age-related functional impairmentBarry J Gurland
Columbia University Stroud Center, Tower 3, Apt 30F, 100 Haven Ave, New York, NY 10032, USA
J Gerontol A Biol Sci Med Sci 59:859-63. 2004..The extent of genetic influence on functioning in later life affects the role of public health, personal initiative, and service interventions... - The Aging, Demographics, and Memory Study: study design and methodsKenneth M Langa
Division of General Medicine, Department of Medicine, University of Michigan Health System, 300 North Ingalls Building, Rm 7E01, Box 4029, Ann Arbor, MI 48109, USA
Neuroepidemiology 25:181-91. 2005..We also illustrate potential uses of the ADAMS data and provide information to interested researchers on obtaining ADAMS and HRS data... - Verification of self-report of zygosity determined via DNA testing in a subset of the NAS-NRC twin registry 40 years laterTerry Reed
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Twin Res Hum Genet 8:362-7. 2005.... - Cognitive function and oral health among community-dwelling older adultsBei Wu
Center on Aging and Department of Community Medicine, West Virginia University, Morgantown, WV 26506, USA
J Gerontol A Biol Sci Med Sci 63:495-500. 2008..Poorer oral health appears to contribute to a decline in quality of life and to be related to various medical conditions. Little is known about the relationship of cognitive function to oral health among community-dwelling older adults... - An adaptation of the modified mini-mental state examination: analysis of demographic influences and normative data: the cache county studyJoAnn T Tschanz
Department of Psychology, Utah State University, Logan, Utah 84322 4440, USA
Neuropsychiatry Neuropsychol Behav Neurol 15:28-38. 2002..To present a new version of the Modified Mini-Mental State Examination (3MS-R), provide normative information extending to individuals in the 10th decade, and examine the effects of demographic variables on test performance... - Cognitive function and dental care utilization among community-dwelling older adultsBei Wu
Center on Aging, West Virginia University, Morgantown 26506, USA
Am J Public Health 97:2216-21. 2007..We sought to investigate the relationship between varying levels of cognitive function and dental care utilization... - Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County StudyPeter P Zandi
Department of Mental Hygiene, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD, USA
JAMA 288:2123-9. 2002..55 [95% CI, 0.21-1.23]). CONCLUSIONS: Prior HRT use is associated with reduced risk of AD, but there is no apparent benefit with current HRT use unless such use has exceeded 10 years...
Research Grants
- GENETIC EPIDEMIOLOGY OF ALZHEIMER'S DISEASE IN TWINSBrenda Plassman; Fiscal Year: 2003..A population-based twin design remains the ideal approach to these sorts of investigations. ..