E D Peterson

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. doi request reprint Challenges in assessing hospital-level stroke mortality as a quality measure: comparison of ischemic, intracerebral hemorrhage, and total stroke mortality rates
    Ying Xian
    Duke Clinical Research Institute, Box 17969, Durham NC 27715, USA
    Stroke 43:1687-90. 2012
  2. ncbi request reprint Association between hospital process performance and outcomes among patients with acute coronary syndromes
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    JAMA 295:1912-20. 2006
  3. ncbi request reprint Procedural volume as a marker of quality for CABG surgery
    Eric D Peterson
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    JAMA 291:195-201. 2004
  4. ncbi request reprint From controlled trials to clinical practice: monitoring transmyocardial revascularization use and outcomes
    Eric D Peterson
    Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 42:1611-6. 2003
  5. ncbi request reprint Early use of glycoprotein IIb/IIIa inhibitors in non-ST-elevation acute myocardial infarction: observations from the National Registry of Myocardial Infarction 4
    Eric D Peterson
    Duke Clinical Research Institute, 2400 Pratt Street, Room 7009, Durham, NC 27705, USA
    J Am Coll Cardiol 42:45-53. 2003
  6. doi request reprint Primary and secondary prevention of cardiovascular disease in older adults: a status report
    Peter Kriekard
    Department of Internal Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Clin Geriatr Med 25:745-55, x. 2009
  7. doi request reprint A call to ACTION (acute coronary treatment and intervention outcomes network): a national effort to promote timely clinical feedback and support continuous quality improvement for acute myocardial infarction
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 2:491-9. 2009
  8. doi request reprint Vision and creation of the American Heart Association pharmaceutical roundtable outcomes research centers
    Eric D Peterson
    Duke Outcomes Research Center, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 2:663-70. 2009
  9. ncbi request reprint Hospital variability in length of stay after coronary artery bypass surgery: results from the Society of Thoracic Surgeon's National Cardiac Database
    Eric D Peterson
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, North Carolina, USA
    Ann Thorac Surg 74:464-73. 2002
  10. ncbi request reprint Willingness to participate in cardiac trials
    Eric D Peterson
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, NC 27710, USA
    Am J Geriatr Cardiol 13:11-5. 2004

Research Grants

  1. Safer Antithrombotic Therapy for Elderly ACS Patients
    Eric Peterson; Fiscal Year: 2006
  2. Duke Cardiovascular CERTs
    Eric Peterson; Fiscal Year: 2007

Collaborators

Detail Information

Publications124 found, 100 shown here

  1. doi request reprint Challenges in assessing hospital-level stroke mortality as a quality measure: comparison of ischemic, intracerebral hemorrhage, and total stroke mortality rates
    Ying Xian
    Duke Clinical Research Institute, Box 17969, Durham NC 27715, USA
    Stroke 43:1687-90. 2012
    ..Public reporting efforts currently profile hospitals based on overall stroke mortality rates, yet the "mix" of hemorrhagic and ischemic stroke cases may impact this rate...
  2. ncbi request reprint Association between hospital process performance and outcomes among patients with acute coronary syndromes
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    JAMA 295:1912-20. 2006
    ..Selected care processes are increasingly being used to measure hospital quality; however, data regarding the association between hospital process performance and outcomes are limited...
  3. ncbi request reprint Procedural volume as a marker of quality for CABG surgery
    Eric D Peterson
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    JAMA 291:195-201. 2004
    ....
  4. ncbi request reprint From controlled trials to clinical practice: monitoring transmyocardial revascularization use and outcomes
    Eric D Peterson
    Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 42:1611-6. 2003
    ..We also identified important risk factors for TMR and compared outcomes of TMR combined with coronary artery bypass graft surgery (TMR + CABG) versus bypass alone in patients receiving incomplete revascularization...
  5. ncbi request reprint Early use of glycoprotein IIb/IIIa inhibitors in non-ST-elevation acute myocardial infarction: observations from the National Registry of Myocardial Infarction 4
    Eric D Peterson
    Duke Clinical Research Institute, 2400 Pratt Street, Room 7009, Durham, NC 27705, USA
    J Am Coll Cardiol 42:45-53. 2003
    ..We sought to identify patient and hospital features associated with early glycoprotein (GP) IIb/IIIa inhibitor therapy for non-ST-elevation (NSTE) myocardial infarction (MI) and to relate this treatment to in-hospital outcomes...
  6. doi request reprint Primary and secondary prevention of cardiovascular disease in older adults: a status report
    Peter Kriekard
    Department of Internal Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Clin Geriatr Med 25:745-55, x. 2009
    ..Guideline recommendations for CVD risk factor modification are also reviewed with emphasis on issues pertaining to the older adult population...
  7. doi request reprint A call to ACTION (acute coronary treatment and intervention outcomes network): a national effort to promote timely clinical feedback and support continuous quality improvement for acute myocardial infarction
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 2:491-9. 2009
    ..This article outlines the objectives, operational structure, patient population, data elements, data collection methodology, and reporting components of this landmark registry...
  8. doi request reprint Vision and creation of the American Heart Association pharmaceutical roundtable outcomes research centers
    Eric D Peterson
    Duke Outcomes Research Center, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 2:663-70. 2009
    ..Participating centers were intended to carry out state-of-the-art outcomes research in cardiovascular disease and stroke, to train the next generation of investigators, and to support the formation of a collaborative research network...
  9. ncbi request reprint Hospital variability in length of stay after coronary artery bypass surgery: results from the Society of Thoracic Surgeon's National Cardiac Database
    Eric D Peterson
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, North Carolina, USA
    Ann Thorac Surg 74:464-73. 2002
    ..We also sought to determine the relationship between hospitals' risk-adjusted PLOS and mortality outcomes...
  10. ncbi request reprint Willingness to participate in cardiac trials
    Eric D Peterson
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, NC 27710, USA
    Am J Geriatr Cardiol 13:11-5. 2004
    ..In conclusion, patient willingness to consider RCT participation does not explain underenrollment of elderly and minority patients. Women, however, were more reluctant to consider RCTs, an area requiring further study...
  11. ncbi request reprint Part II: Sealing holes in the safety net
    Eric D Peterson
    Centers for Education and Research on Therapeutics CERTs Coordinating Center, Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 147:985-90. 2004
  12. doi request reprint Trends in quality of care for patients with acute myocardial infarction in the National Registry of Myocardial Infarction from 1990 to 2006
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 156:1045-55. 2008
    ..Furthermore, it is unknown whether gender-, race-, and age-based care disparities have narrowed over time...
  13. ncbi request reprint Multicenter experience in revascularization of very elderly patients
    Eric D Peterson
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 148:486-92. 2004
    ..We pooled the largest PCI and CABG clinical registries in the United States to better understand revascularization procedure use, risks and outcomes in patients aged > or =75 years...
  14. doi request reprint Implementing critical pathways and a multidisciplinary team approach to cardiovascular disease management
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 102:47G-56G. 2008
    ..In addition, the use of the "pay for performance" method, which can be advantageous for patients, physicians, and hospitals, may potentially improve the care of post-MI patients with LVD...
  15. ncbi request reprint Should we link payment to quality?
    Eric D Peterson
    Duke University Medical Center and Duke Clinical Research Institute, Durham, NC 27710, USA
    Am Heart J 148:S56-8. 2004
    ..While many clinicians would generally agree with the concept that providing better medical care should be rewarded, putting the idea into practice poses a challenge...
  16. ncbi request reprint Lessons learned from the CRUSADE National Quality Improvement Initiative
    Eric D Peterson
    Duke Clinical Research Institute, 2400 Pratt Street, Room 7009, Durham, NC 27705, USA
    Curr Cardiol Rep 10:285-90. 2008
    ..Ongoing quality improvement efforts will be needed to further improve evidence-based and personalized care of patients with ACS...
  17. ncbi request reprint The burden of angina pectoris and its complications [corrected]
    Eric Peterson
    Duke University Medical Center, Duke Clinical Research Institute, Box 17969, Durham, NC 27715, USA
    Clin Cardiol 30:I10-5. 2007
    ..The effectiveness of treatment, revascularization and medical therapies, on reducing angina symptoms is also reviewed...
  18. ncbi request reprint Association of evidence-based care processes and outcomes among patients with acute coronary syndromes: performance matters
    Eric D Peterson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    J Cardiovasc Nurs 23:50-5. 2008
    ..Our findings support the use of broad, guideline-based performance metrics as a means of assessing and helping improve hospital quality...
  19. doi request reprint Contemporary mortality risk prediction for percutaneous coronary intervention: results from 588,398 procedures in the National Cardiovascular Data Registry
    Eric D Peterson
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 55:1923-32. 2010
    ..We sought to create contemporary models for predicting mortality risk following percutaneous coronary intervention (PCI)...
  20. doi request reprint The NCDR ACTION Registry-GWTG: transforming contemporary acute myocardial infarction clinical care
    Eric D Peterson
    Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC 27705, USA
    Heart 96:1798-802. 2010
    ..Data are available for research by application to: http://www.ncdr.com...
  21. ncbi request reprint Effect of gender on the outcomes of contemporary percutaneous coronary intervention
    E D Peterson
    The Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 88:359-64. 2001
    ..We conclude that in contemporary practice, a patient's body size rather than gender, conveys independent risk for mortality after PCI...
  22. ncbi request reprint Acute and long-term cost implications of coronary stenting
    E D Peterson
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 33:1610-8. 1999
    ..We compared the acute and one year medical costs and outcomes of coronary stenting with those for balloon angioplasty (percutaneous transluminal coronary angioplasty) in contemporary clinical practice...
  23. ncbi request reprint Representation of elderly persons and women in published randomized trials of acute coronary syndromes
    P Y Lee
    Department of Medicine, Duke University Medical Center, Box 3236, Durham, NC 27710, USA
    JAMA 286:708-13. 2001
    ..Elderly persons and women were underrepresented in randomized controlled trials (RCTs) prior to 1990. Since then, efforts have been made to correct these biases, but their effect is unclear...
  24. ncbi request reprint Evolving trends in interventional device use and outcomes: results from the National Cardiovascular Network Database
    E D Peterson
    Division of Cardiology, Department of Medicine and the Division of Biometry, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am Heart J 139:198-207. 2000
    ..Although multiple new coronary interventional devices have been approved for marketing in the United States, use of these technologies in general clinical practice and their associated outcomes have not been reported...
  25. ncbi request reprint The effects of New York's bypass surgery provider profiling on access to care and patient outcomes in the elderly
    E D Peterson
    Duke Clinical Research Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 32:993-9. 1998
    ..The aim of this study was to examine the effects of provider profiling on bypass surgery access and outcomes in elderly patients in New York...
  26. ncbi request reprint Lipid management in patients with unstable angina pectoris and non-ST-segment elevation acute myocardial infarction (from CRUSADE)
    JoAnne M Foody
    Section of Cardiovascular Medicine, Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA
    Am J Cardiol 95:483-5. 2005
    ....
  27. ncbi request reprint Impact of early discharge after coronary artery bypass graft surgery on rates of hospital readmission and death. The Ischemic Heart Disease (IHD) Patient Outcomes Research Team (PORT) Investigators
    P A Cowper
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Cardiol 30:908-13. 1997
    ..This study examined the impact of early hospital discharge on short-term clinical outcomes of elderly patients treated with coronary artery bypass graft surgery (CABG) in the United States in 1992...
  28. ncbi request reprint Heart failure with preserved left ventricular systolic function among patients with non-ST-segment elevation acute coronary syndromes
    Kyla M Bennett
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
    Am J Cardiol 99:1351-6. 2007
    ..Guideline-recommended therapies and interventions are under-utilized in patients with NSTE ACS and HF, with and without preserved systolic function, compared with those without HF...
  29. doi request reprint Quality of care for atrial fibrillation among patients hospitalized for heart failure
    Jonathan P Piccini
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 54:1280-9. 2009
    ..This study sought to examine quality of care and warfarin use at discharge in patients with atrial fibrillation (AF) and heart failure (HF)...
  30. doi request reprint Timing of in-hospital coronary artery bypass graft surgery for non-ST-segment elevation myocardial infarction patients results from the National Cardiovascular Data Registry ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network
    Shailja V Parikh
    Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
    JACC Cardiovasc Interv 3:419-27. 2010
    ..The aim of this study was to examine timing of in-hospital coronary artery bypass graft surgery (CABG) for non-ST-segment elevation myocardial infarction (NSTEMI) patients...
  31. ncbi request reprint Relationship between diabetes mellitus and long-term survival after coronary bypass and angioplasty
    G W Barsness
    Duke Heart Center, Duke University Medical Center, Durham, NC, USA
    Circulation 96:2551-6. 1997
    ..We studied the relationship between diabetes and survival after revascularization in a large prospective cohort of patients with multivessel coronary artery disease...
  32. doi request reprint Medical records and quality of care in acute coronary syndromes: results from CRUSADE
    Shannon M Dunlay
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Arch Intern Med 168:1692-8. 2008
    ..Patient medical records are important means of communication among health care providers. Limited evaluation has been performed of the quality of the medical records or its association with health care processes or outcomes...
  33. ncbi request reprint Moving from evidence to practice in the care of patients who have acute coronary syndrome
    Kelly L Miller
    Division of Cardiology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Cardiol Clin 24:87-102. 2006
    ..Lessons learned from previous and ongoing quality improvement initiatives will provide the tools needed to ensure that widespread adoption of guideline-based therapy is complete...
  34. doi request reprint Alternative pay-for-performance scoring methods: implications for quality improvement and patient outcomes
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
    Med Care 47:1062-8. 2009
    ..Alternative methods that weight process measures according to how hospitals organize care and the range for possible improvement may be more closely related to patient outcomes...
  35. ncbi request reprint Use of a prognostic treadmill score in identifying diagnostic coronary disease subgroups
    L J Shaw
    Center For Cardiovascular Epidemiology, Division of Cardiology, Emory University, Atlanta, GA, USA
    Circulation 98:1622-30. 1998
    ..However, its usefulness for providing diagnostic estimates has yet to be determined...
  36. ncbi request reprint Potential impact of evidence-based medicine in acute coronary syndromes: insights from GUSTO-IIb. Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes trial
    K P Alexander
    Duke Clinical Research Institute, Durham, North Carolina 27705, USA
    J Am Coll Cardiol 32:2023-30. 1998
    ..The purpose of this study to determine whether use of cardiac medications reflects evidence-based recommendations for patients with non-ST elevation acute coronary syndromes...
  37. ncbi request reprint The impact of statistical adjustment on economic profiles of interventional cardiologists
    P A Cowper
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 38:1416-23. 2001
    ..The objective of this study was to identify preprocedure patient factors associated with percutaneous intervention costs and to examine the impact of these patient factors on economic profiles of interventional cardiologists...
  38. doi request reprint Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    N Engl J Med 361:235-44. 2009
    ....
  39. doi request reprint The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 2--isolated valve surgery
    Sean M O'Brien
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Ann Thorac Surg 88:S23-42. 2009
    ..Expanding upon existing valve models, the new STS models include several nonfatal complications in addition to mortality...
  40. ncbi request reprint Impact of acute beta-blocker therapy for patients with non-ST-segment elevation myocardial infarction
    Chadwick D Miller
    Wake Forest University Health Sciences, Winston Salem, NC, USA
    Am J Med 120:685-92. 2007
    ..We sought to determine the impact of acute beta-blocker therapy on outcomes in patients with NSTEMI...
  41. ncbi request reprint Cost effectiveness of early discharge after uncomplicated acute myocardial infarction
    L K Newby
    Duke Clinical Research Institute, Durham, NC 27715 7969, USA
    N Engl J Med 342:749-55. 2000
    ..Reducing the length of hospitalizations can reduce short-term costs, but there are few data on the long-term clinical and economic consequences of early discharge...
  42. ncbi request reprint Clinical characteristics, process of care, and outcomes of Hispanic patients presenting with non-ST-segment elevation acute coronary syndromes: results from Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early imp
    Mauricio G Cohen
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7075, USA
    Am Heart J 152:110-7. 2006
    ..Data regarding the management of non-ST-segment elevation acute coronary syndromes (NSTE ACS) in Hispanic patients, the largest and fastest-growing minority in the United States, are scarce...
  43. ncbi request reprint Outcomes associated with the use of secondary prevention medications after coronary artery bypass graft surgery
    Abhinav Goyal
    Duke Clinical Research Institute and Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 83:993-1001. 2007
    ..We investigated whether greater use of secondary prevention medications after coronary artery bypass graft surgery is associated with improved clinical outcomes...
  44. doi request reprint Cardiac surgery in infants with low birth weight is associated with increased mortality: analysis of the Society of Thoracic Surgeons Congenital Heart Database
    Christopher L Curzon
    Department of Pediatrics, Division of Pediatric Cardiology, Duke University Medical Center, Durham, NC 27710, USA
    J Thorac Cardiovasc Surg 135:546-51. 2008
    ....
  45. pmc Sex differences in mortality after acute myocardial infarction: changes from 1994 to 2006
    Viola Vaccarino
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Arch Intern Med 169:1767-74. 2009
    ..Previous studies have shown that women younger than 55 years have higher hospital mortality rates after acute myocardial infarction (MI) than age-matched men. We examined whether such mortality differences have decreased in recent years...
  46. ncbi request reprint Effect of cardiac rehabilitation on functional outcomes after coronary revascularization
    Sara K Pasquali
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 145:445-51. 2003
    ..The main objective of this study was to evaluate the impact of CR in a diverse contemporary population on patient functional outcomes...
  47. doi request reprint Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes
    Chiara Melloni
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    J Am Coll Cardiol 51:991-6. 2008
    ..Our purpose was to compare formulae for estimating glomerular filtration rate (GFR) in non-ST-segment elevation acute coronary syndromes (NSTE ACS) patients...
  48. ncbi request reprint Pay for performance, quality of care, and outcomes in acute myocardial infarction
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke University Medical Center, Durham, NC, USA
    JAMA 297:2373-80. 2007
    ..In 2003, the Centers for Medicare & Medicaid Services (CMS) launched the largest pay-for-performance pilot project to date in the United States, including indicators for acute myocardial infarction...
  49. ncbi request reprint Outcomes of cardiac surgery in patients > or = 80 years: results from the National Cardiovascular Network
    K P Alexander
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 35:731-8. 2000
    ..The purpose of this study was to evaluate characteristics and outcomes of patients age > or =80 undergoing cardiac surgery...
  50. doi request reprint Association of early follow-up after acute myocardial infarction with higher rates of medication use
    Stacie L Daugherty
    Department of Medicine, Division of Cardiology, University of Colorado Denver Health Sciences Center, Denver, CO, USA
    Arch Intern Med 168:485-91; discussion 492. 2008
    ..Early outpatient follow-up after acute myocardial infarction (AMI) is recommended in guidelines, but its relationship with the use of evidence-based therapies is unknown...
  51. doi request reprint Use of cardiac resynchronization therapy in patients hospitalized with heart failure
    Jonathan P Piccini
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 118:926-33. 2008
    ....
  52. ncbi request reprint Age, functional capacity, and health-related quality of life in patients with heart failure
    Frederick A Masoudi
    Department of Medicine, Denver Health Medical Center, Colorado 80204, USA
    J Card Fail 10:368-73. 2004
    ..We compared the relationship between functional limitation and HRQL between older and younger patients with heart failure...
  53. ncbi request reprint Should coronary artery bypass graft surgery patients with mild or moderate aortic stenosis undergo concomitant aortic valve replacement? A decision analysis approach to the surgical dilemma
    William T Smith
    Duke University Medical Center, Durham, North Carolina, USA
    J Am Coll Cardiol 44:1241-7. 2004
    ..Multiple sensitivity analyses were also performed to determine the variables that most profoundly affect outcome...
  54. ncbi request reprint Value of exercise treadmill testing in women
    K P Alexander
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 32:1657-64. 1998
    ..We sought to determine the ability of a treadmill score to provide accurate diagnostic and prognostic risk estimates in women...
  55. ncbi request reprint Evaluating the potential 'economic attractiveness' of new therapies in patients with non-ST elevation acute coronary syndrome
    E L Eisenstein
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Pharmacoeconomics 17:263-72. 2000
    ..To evaluate the relationship between how much a new cardiovascular therapy improves clinical outcomes over current therapies and how much more it can cost while still remaining 'economically attractive'...
  56. ncbi request reprint Post-myocardial infarction risk stratification in elderly patients
    K P Alexander
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 142:37-42. 2001
    ..In particular, concern has been raised that the elderly, who are at high risk for recurrent ischemia and short-term death, are not referred as often as younger patients for post-MI testing...
  57. ncbi request reprint Using observational data to estimate prognosis: an example using a coronary artery disease registry
    E R DeLong
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Duke University, Department of Medicine, Biometry Division, Community and Family Medicine, 2400 Pratt Street, Durham, NC 27705, USA
    Stat Med 20:2505-32. 2001
    ..This paper discusses these issues and suggests strategies to deal with them. A proposed methodology is developed, applied and evaluated on a large observational database that has long-term follow-up on nearly 10 000 patients...
  58. ncbi request reprint Provisional stenting strategies: systematic overview and implications for clinical decision-making
    W J Cantor
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Am Coll Cardiol 36:1142-51. 2000
    ..Provisional stenting may potentially reduce costs and rates of in-stent restenosis without compromising the quality of health care delivery...
  59. doi request reprint Potential unintended financial consequences of pay-for-performance on the quality of care for minority patients
    Amrita M Karve
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 155:571-6. 2008
    ..The purpose of this study was to determine whether pay-for-performance (PFP) increases existing racial care disparities...
  60. ncbi request reprint The evolving role of glycoprotein IIb/IIIa inhibitor therapy in contemporary care of acute coronary syndrome patients
    Pierluigi Tricoci
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    J Interv Cardiol 19:449-55. 2006
    ..This review discusses, in the light of clinical trials recently presented, what we know, what we are learning, and what we still need to learn...
  61. ncbi request reprint Low-molecular-weight heparin compared with unfractionated heparin for patients with non-ST-segment elevation acute coronary syndromes treated with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE initiative
    Kanwar P Singh
    Division of Cardiology and Duke Clinical Research Institute, Durham, NC 27705, USA
    J Thromb Thrombolysis 21:211-20. 2006
    ..We sought to compare the efficacy and safety of these treatment strategies in a large contemporary population of patients with NSTE ACS...
  62. pmc Impact of delay in door-to-needle time on mortality in patients with ST-segment elevation myocardial infarction
    Robert L McNamara
    Department of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA
    Am J Cardiol 100:1227-32. 2007
    ..87, respectively; p for trend <0.001). In conclusion, timely administration of fibrinolytic therapy continues to significantly impact on mortality in the modern era, particularly in patients presenting early after symptom onset...
  63. ncbi request reprint Quality of care by classification of myocardial infarction: treatment patterns for ST-segment elevation vs non-ST-segment elevation myocardial infarction
    Matthew T Roe
    Division of Cardiology, Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27705, USA
    Arch Intern Med 165:1630-6. 2005
    ....
  64. doi request reprint Patient satisfaction and its relationship with clinical quality and inpatient mortality in acute myocardial infarction
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke University, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 3:188-95. 2010
    ..The objective of this study was to determine whether patient satisfaction is associated with adherence to practice guidelines and outcomes for acute myocardial infarction and to identify the key drivers of patient satisfaction...
  65. doi request reprint Quality of care and in-hospital outcomes in patients with coronary heart disease in rural and urban hospitals (from Get With the Guidelines-Coronary Artery Disease Program)
    Amrut V Ambardekar
    Division of Cardiology, Denver Health Medical Center, The University of Colorado at Denver and the Health Sciences Center, Denver, Colorado, USA
    Am J Cardiol 105:139-43. 2010
    ..87 to 1.26). In conclusion, within the GWTG-CAD quality improvement initiative, patients with CAD treated at rural hospitals receive similar quality of care and have similar outcomes as those at urban centers...
  66. ncbi request reprint Relation between hospital intra-aortic balloon counterpulsation volume and mortality in acute myocardial infarction complicated by cardiogenic shock
    Edmond W Chen
    Division of Cardiology, Kaiser Permanente Medical Group, Inc, Richmond, CA 94801 3195, USA
    Circulation 108:951-7. 2003
    ....
  67. pmc Laparoscopic versus open appendectomy: outcomes comparison based on a large administrative database
    Ulrich Guller
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Surg 239:43-52. 2004
    ..To compare length of hospital stay, in-hospital complications, in-hospital mortality, and rate of routine discharge between laparoscopic and open appendectomy based on a representative, nationwide database...
  68. ncbi request reprint Part I: Identifying holes in the safety net
    J Conor O'Shea
    Duke Center for Education and Research on Therapeutics CERTs Research Center, Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 147:977-84. 2004
  69. pmc Center variation and outcomes associated with delayed sternal closure after stage 1 palliation for hypoplastic left heart syndrome
    Jason N Johnson
    Division of Pediatric Cardiology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27715, USA
    J Thorac Cardiovasc Surg 139:1205-10. 2010
    ..We describe center variation in delayed sternal closure after stage 1 palliation and associated outcomes...
  70. ncbi request reprint Care of non-ST-segment elevation patients: insights from the CRUSADE national quality improvement initiative
    E Magnus Ohman
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am Heart J 148:S34-9. 2004
    ..These ACC/AHA guidelines are intended to help physicians make appropriate decisions when diagnosing and treating patients with NSTE ACS...
  71. ncbi request reprint Medical and surgical management of coronary artery disease in women
    K P Alexander
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC, USA
    Am J Manag Care 7:951-6. 2001
    ....
  72. doi request reprint Use of guidelines-recommended management and outcomes among women and men with low-level troponin elevation: insights from CRUSADE
    Sharif A Halim
    Department of Medicine and the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715 7969, USA
    Circ Cardiovasc Qual Outcomes 2:199-206. 2009
    ..5x ULN) remains uncertain. Using the CRUSADE database, we explored relationships between sex and treatment and outcomes among patients with troponin 1 to 1.5x ULN...
  73. doi request reprint Impact of perioperative myocardial infarction on angiographic and clinical outcomes following coronary artery bypass grafting (from PRoject of Ex-vivo Vein graft ENgineering via Transfection [PREVENT] IV)
    James M Yau
    Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 102:546-51. 2008
    ..Further research is needed into the prevention and treatment of perioperative MI in patients undergoing CABG...
  74. ncbi request reprint A framework for quality improvement: an analysis of factors responsible for improvement at hospitals participating in the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelin
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke University Medical Center, Durham, NC, USA
    Am Heart J 154:1206-20. 2007
    ....
  75. ncbi request reprint Long-term adherence with cardiovascular drug regimens
    Sonali P Kulkarni
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 151:185-91. 2006
    ..An increasing number of medications are prescribed for patients with coronary artery disease, but poor adherence may limit realization of their benefits...
  76. ncbi request reprint Risk-adjusted short- and long-term outcomes for on-pump versus off-pump coronary artery bypass surgery
    Matthew L Williams
    Division of Cardiothoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27703, USA
    Circulation 112:I366-70. 2005
    ..However, long-term outcome of OPCAB compared with conventional coronary artery bypass grafting (CABG) remains poorly defined...
  77. ncbi request reprint Clinical and economic implications of the Multicenter Automatic Defibrillator Implantation Trial-II
    Sana M Al-Khatib
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    Ann Intern Med 142:593-600. 2005
    ..3 or less...
  78. ncbi request reprint A comparison of acute coronary syndrome care at academic and nonacademic hospitals
    Manesh R Patel
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am J Med 120:40-6. 2007
    ..We sought to identify hospital characteristics associated with high levels of adherence in order to gain insight into successful processes of care...
  79. ncbi request reprint Influence of age on outcomes in patients undergoing mitral valve replacement
    Rajendra H Mehta
    Division of Cardiology, University of Michigan, Ann Arbor 48105, USA
    Ann Thorac Surg 74:1459-67. 2002
    ....
  80. ncbi request reprint The evaluation of treatment when center-specific selection criteria vary with respect to patient risk
    Elizabeth R DeLong
    The Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    Biometrics 61:942-9. 2005
    ..An example that examines the effect of early extubation after bypass surgery is also presented...
  81. ncbi request reprint Racial differences in the outcomes of patients with diastolic heart failure
    Mark A East
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 148:151-6. 2004
    ..This is particularly common in African American patients, yet there have been few studies examining the long-term natural history of this disorder in African-American and white patients...
  82. ncbi request reprint Effect of door-to-balloon time on mortality in patients with ST-segment elevation myocardial infarction
    Robert L McNamara
    Department of Medicine, Section of Cardiovascular Medicine, Seattle, Washington, USA
    J Am Coll Cardiol 47:2180-6. 2006
    ..We sought to determine the effect of door-to-balloon time on mortality for patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI)...
  83. ncbi request reprint Outcomes of acute myocardial infarction in the Department of Veterans Affairs: does regionalization of health care work?
    S M Wright
    Health Services Research and Development, Department of Medicine, Brockton West Roxbury Veterans Affairs Medical Center, MA 02132, USA
    Med Care 35:128-41. 1997
    ..Patients using the VA regional medical system initially are admitted to a hospital with or without the on-site availability of technology-intensive cardiac services...
  84. pmc Major infection after pediatric cardiac surgery: a risk estimation model
    Gregory M Barker
    Duke University Medical Center, Durham, North Carolina, USA
    Ann Thorac Surg 89:843-50. 2010
    ..In pediatric cardiac surgery, infection is a leading cause of morbidity and mortality. We created a model to predict risk of major infection in this population...
  85. ncbi request reprint The implications of blood transfusions for patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative
    Xin Yang
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 46:1490-5. 2005
    ....
  86. ncbi request reprint Laparoscopic appendectomy in the elderly
    Ulrich Guller
    Department of Surgery, the Center for Excellence in Surgical Outcomes, Duke University Medical Center, Durham, NC, USA
    Surgery 135:479-88. 2004
    ..Evidence suggests that laparoscopic appendectomy (LA) has advantages over open appendectomy (OA) in the treatment of appendicitis. It remains, however, unclear whether LA is indicated in the elderly patient population...
  87. doi request reprint Regional differences in quality of care and outcomes for the treatment of acute coronary syndromes: an analysis from the get with the guidelines coronary artery disease program
    Warren Laskey
    Division of Cardiology, Department of Internal Medicine, MSC10 5550, 1 University of New Mexico, Albuquerque, NM 87131, USA
    Crit Pathw Cardiol 9:1-7. 2010
    ..The effect of hospital participation in a national performance improvement program on regional variation in quality of care and in-hospital outcomes for acute coronary syndromes (ACS) is unknown...
  88. ncbi request reprint Cardiac rehabilitation in the elderly
    S K Pasquali
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 142:748-55. 2001
    ..However, innovative recommendation and referral strategies are needed because few elderly patients actually enroll...
  89. ncbi request reprint Impact of an interactive video on decision making of patients with ischemic heart disease
    L Liao
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Gen Intern Med 11:373-6. 1996
    ..0001). The greatest effects appeared to be concentrated in those patients with less education (p = .04), and the program appeared to increase anxiety in nonwhite patients compared with white patients (p = 0.07)...
  90. ncbi request reprint Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up
    K P Alexander
    Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 38:1-7. 2001
    ..This study explored the association between the initiation of hormone replacement therapy (HRT) and early cardiac events (<1 year) in women with a recent myocardial infarction (MI)...
  91. pmc Alabama coronary artery bypass grafting project: results from phase II of a statewide quality improvement initiative
    William L Holman
    Birmingham VA Medical Center, University of Alabama at Birmingham, Birmingham, AL, USA
    Ann Surg 239:99-109. 2004
    ..This report describes the first round of results for Phase II of the Alabama CABG Project, a regional quality improvement initiative...
  92. doi request reprint Anatomic distribution of the culprit lesion in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: findings from the National Cardiovascular Data Registry
    William C Dixon
    J Am Coll Cardiol 52:1347-8. 2008
  93. ncbi request reprint Cardiology management improves secondary prevention measures among patients with coronary artery disease
    P Michael Ho
    Health Services Research, Denver Veterans Affairs Medical Center, University of Colorado Health Sciences Center, 80220, USA
    J Am Coll Cardiol 43:1517-23. 2004
    ..The goal of this study was to determine if cardiology subspecialty involvement improves the attainment of recommended low-density lipoprotein (LDL) cholesterol and blood pressure (BP) targets in coronary artery disease (CAD) patients...
  94. ncbi request reprint Long-term mortality of patients with acute myocardial infarction in the United States and Canada: comparison of patients enrolled in Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I
    Padma Kaul
    University of Alberta, 7221 Aberhart Center I, 8440 112 St, Edmonton, AB T6G 2B7, Canada
    Circulation 110:1754-60. 2004
    ..4%, adjusted P=0.02). We sought to determine whether Canadian-US differences in practice patterns in GUSTO-I had an impact on 5-year mortality...
  95. ncbi request reprint Influence of the Angioplasty Revascularization Investigation National Heart, Lung, and Blood Institute Diabetic Clinical Alert on practice patterns: results from the National Cardiovascular Network Database
    Darren K McGuire
    University of Texas Southwestern Medical Center, Dallas, Tex, USA
    Circulation 107:1864-70. 2003
    ..quot; The influence of the BARI findings and of the Clinical Alert on practice patterns is unknown...
  96. ncbi request reprint The Society of Thoracic Surgeons: 30-day operative mortality and morbidity risk models
    A Laurie W Shroyer
    Denver Department of Veterans Affairs Medical Center, Denver, Colorado 80220, USA
    Ann Thorac Surg 75:1856-64; discussion 1864-5. 2003
    ..This study identified the preoperative risk factors associated with several complications and a composite outcome (the presence of any major morbidity or 30-day operative mortality or both)...
  97. ncbi request reprint 2002 update to the ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: implications for emergency department practice
    Charles V Pollack
    University of Pennsylvania Health System, Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA
    Ann Emerg Med 41:355-69. 2003
    ..Several of the modified and new recommendations again potentially affect ED management. These are presented and discussed here...
  98. ncbi request reprint Development and validation of a simple model to predict severe coronary artery disease after myocardial infarction: potential impact on cardiac catheterization use in the United States and Canada
    Wayne B Batchelor
    Heart and Vascular Institute, Tallahassee Memorial Healthcare, Tallahassee, FL, USA
    Am Heart J 145:349-55. 2003
    ....
  99. ncbi request reprint Improving the care of patients with non-ST-elevation acute coronary syndromes in the emergency department: the CRUSADE initiative
    James W Hoekstra
    Ohio State University, Columbus, OH 43210, USA
    Acad Emerg Med 9:1146-55. 2002
    ..It is the intent of CRUSADE to improve patient care in the ED by tracking and encouraging compliance with evidence-based guidelines for the evaluation and management of NSTE ACS...
  100. ncbi request reprint Characteristics, management, and outcomes of 5,557 patients age > or =90 years with acute coronary syndromes: results from the CRUSADE Initiative
    Adam H Skolnick
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Am Coll Cardiol 49:1790-7. 2007
    ..The goal of this work was to explore the treatment and outcomes of patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) age > or =90 years...
  101. ncbi request reprint Internal thoracic artery grafting in the elderly patient undergoing coronary artery bypass grafting: room for process improvement?
    T Bruce Ferguson
    Surgery and Physiology, LSU Health Sciences Center, New Orleans, LA 70112 2822, USA
    J Thorac Cardiovasc Surg 123:869-80. 2002
    ..This study examined the use, complication risks, and operative (30-day) mortality associated with internal thoracic artery grafting in patients 75 years of age and older...

Research Grants3

  1. Safer Antithrombotic Therapy for Elderly ACS Patients
    Eric Peterson; Fiscal Year: 2006
    ..Finally, we will use established relations with professional societies and the VHA to widely disseminate our study's major findings. ..
  2. Duke Cardiovascular CERTs
    Eric Peterson; Fiscal Year: 2007
    ..4. Widely disseminate those interventions found to be effective. 5. Train the next generation of CV outcomes researchers. ..