Research Topics
Species | Amy M PastvaSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient miceAmy M Pastva
Duke University Medical Center, Durham, NC 27710, USA
Am J Respir Cell Mol Biol 44:175-84. 2011..These findings may have clinical significance, because recent studies reported associations between surfactant protein polymorphisms and a variety of lung diseases...
Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferationSambuddho Mukherjee
Department of Cell Biology, Duke University Medical Center, Durham NC 27710, USA
J Immunol 188:957-67. 2012..These effects are intrinsic to the global T cell population and are manifested in vivo in naive as well as memory phenotype T cells. Thus, SP-A appears to integrate signal thresholds to control T cell proliferation...
Surfactant protein A modulates induction of regulatory T cells via TGF-βSambuddho Mukherjee
Department of Cell Biology, Duke University Medical Center, Durham NC 27710, USA
J Immunol 188:4376-84. 2012..Taken together, these findings support the hypothesis that SP-A affects T cell immune function by the induction of Tregs during activation...
Novel role for surfactant protein A in gastrointestinal graft-versus-host diseaseKymberly M Gowdy
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
J Immunol 188:4897-905. 2012..The results of these studies demonstrate that SP-A protects against the development of GI GVHD and establishes a role for SP-A in regulating the immune response in the GI tract...
Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammationAmy M Pastva
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
J Immunol 186:2842-9. 2011....
