- Cilia in vertebrate development and diseaseEdwin C Oh
Center for Human Disease Modeling, Department of Cell Biology, Duke University, Durham NC 27710, USA
Development 139:443-8. 2012..Here, we provide a snapshot of the structure, function and distribution of the vertebrate cilium and of the pathologies that are associated with its dysfunction...
- Context-dependent regulation of Wnt signaling through the primary ciliumEdwin C Oh
Center for Human Disease Modeling, Department of Cell Biology, 466 Nanaline Building, Duke University, Durham, NC 27710, USA
J Am Soc Nephrol 24:10-8. 2013..Among the many pathways, here we discuss the emerging role of Wnt proteins in morphogenic signaling and ciliary biology during health and disease...
- Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entrySehyun Kim
Department of Cell Biology, University of Oklahoma Health Sciences Center, 975 NE 10th Street, Oklahoma City, Oklahoma 73104, USA
Nat Cell Biol 13:351-60. 2011..These data suggest that Nde1 is an integral component of a network coordinating ciliary length with cell cycle progression and have implications for understanding the transition from a quiescent to a proliferative state...
- KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variantChristelle Golzio
Center for Human Disease Modeling and Department of Cell biology, Duke University, Durham, North Carolina 27710, USA
Nature 485:363-7. 2012..2 CNV, reinforce the idea that one or a small number of transcripts within a CNV can underpin clinical phenotypes, and offer an efficient route to identifying dosage-sensitive loci...