MIGUEL A NICOLELIS

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Unscented Kalman filter for brain-machine interfaces
    Zheng Li
    Department of Computer Science, Duke University, Durham, North Carolina, United States of America
    PLoS ONE 4:e6243. 2009
  2. pmc Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep
    Kafui Dzirasa
    Department of Neurobiology, Duke University Medical Center, Durham, NC, USA
    PLoS ONE 4:e5238. 2009
  3. pmc Perceiving invisible light through a somatosensory cortical prosthesis
    Eric E Thomson
    Department of Neurobiology, Duke University, Box 3209, 311 Research Drive, Bryan Research, Durham, North Carolina 27710, USA
    Nat Commun 4:1482. 2013
  4. pmc Future developments in brain-machine interface research
    Mikhail A Lebedev
    Duke University, Durham, NC, USA
    Clinics (Sao Paulo) 66:25-32. 2011
  5. pmc Comprehensive analysis of tissue preservation and recording quality from chronic multielectrode implants
    Marco Aurelio M Freire
    Edmond and Lily Safra International Institute of Neuroscience of Natal, Natal RN, Brazil
    PLoS ONE 6:e27554. 2011
  6. pmc Chronic Spinal Cord Electrical Stimulation Protects Against 6-hydroxydopamine Lesions
    Amol P Yadav
    Department of Biomedical Engineering, Duke University, Durham, NC, 27780
    Sci Rep 4:3839. 2014
  7. pmc Extracting kinematic parameters for monkey bipedal walking from cortical neuronal ensemble activity
    Nathan A Fitzsimmons
    Department of Neurobiology, Duke University Durham, NC, USA
    Front Integr Neurosci 3:3. 2009
  8. pmc Cortical correlates of fitts' law
    Peter J Ifft
    Department of Biomedical Engineering, Duke University Durham, NC, USA
    Front Integr Neurosci 5:85. 2011
  9. pmc A brain-machine interface instructed by direct intracortical microstimulation
    Joseph E O'Doherty
    Department of Biomedical Engineering, Duke University Durham, NC, USA
    Front Integr Neurosci 3:20. 2009
  10. pmc A brain-to-brain interface for real-time sharing of sensorimotor information
    Miguel Pais-Vieira
    Department of Neurobiology, Duke University, Durham, NC 27710, USA
    Sci Rep 3:1319. 2013

Research Grants

Collaborators

Detail Information

Publications74

  1. pmc Unscented Kalman filter for brain-machine interfaces
    Zheng Li
    Department of Computer Science, Duke University, Durham, North Carolina, United States of America
    PLoS ONE 4:e6243. 2009
    ..The 10th order unscented Kalman filter outperformed the standard Kalman filter and the Wiener filter in both off-line reconstruction of movement trajectories and real-time, closed-loop BMI operation...
  2. pmc Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep
    Kafui Dzirasa
    Department of Neurobiology, Duke University Medical Center, Durham, NC, USA
    PLoS ONE 4:e5238. 2009
    ..Thus, we propose that persistent hyperdopaminergia, together with secondary alterations in other neuromodulatory systems, results in lower frequency activity in neural systems responsible for various cognitive processes...
  3. pmc Perceiving invisible light through a somatosensory cortical prosthesis
    Eric E Thomson
    Department of Neurobiology, Duke University, Box 3209, 311 Research Drive, Bryan Research, Durham, North Carolina 27710, USA
    Nat Commun 4:1482. 2013
    ..Hence, sensory cortical prostheses, in addition to restoring normal neurological functions, may serve to expand natural perceptual capabilities in mammals...
  4. pmc Future developments in brain-machine interface research
    Mikhail A Lebedev
    Duke University, Durham, NC, USA
    Clinics (Sao Paulo) 66:25-32. 2011
    ....
  5. pmc Comprehensive analysis of tissue preservation and recording quality from chronic multielectrode implants
    Marco Aurelio M Freire
    Edmond and Lily Safra International Institute of Neuroscience of Natal, Natal RN, Brazil
    PLoS ONE 6:e27554. 2011
    ..Altogether, our results indicate that chronic tungsten multielectrode implants do not substantially alter the histological and functional integrity of target sites in the cerebral cortex...
  6. pmc Chronic Spinal Cord Electrical Stimulation Protects Against 6-hydroxydopamine Lesions
    Amol P Yadav
    Department of Biomedical Engineering, Duke University, Durham, NC, 27780
    Sci Rep 4:3839. 2014
    ..These results suggest that DCS has a chronic therapeutical and neuroprotective effect, increasing its potential as a new clinical option for treating PD patients. ..
  7. pmc Extracting kinematic parameters for monkey bipedal walking from cortical neuronal ensemble activity
    Nathan A Fitzsimmons
    Department of Neurobiology, Duke University Durham, NC, USA
    Front Integr Neurosci 3:3. 2009
    ..Extraction was further improved using a switching decoder which designated a submodel for each walking paradigm. We propose that BMIs may one day allow severely paralyzed patients to walk again...
  8. pmc Cortical correlates of fitts' law
    Peter J Ifft
    Department of Biomedical Engineering, Duke University Durham, NC, USA
    Front Integr Neurosci 5:85. 2011
    ..We suggest that sensorimotor cortex activity reflects the characteristics of both the movement and the target. Classifiers that extract these parameters from cortical ensembles could improve neuroprosthetic control...
  9. pmc A brain-machine interface instructed by direct intracortical microstimulation
    Joseph E O'Doherty
    Department of Biomedical Engineering, Duke University Durham, NC, USA
    Front Integr Neurosci 3:20. 2009
    ..We propose that in the future, bidirectional BMIs incorporating ICMS may become an effective paradigm for sensorizing neuroprosthetic devices...
  10. pmc A brain-to-brain interface for real-time sharing of sensorimotor information
    Miguel Pais-Vieira
    Department of Neurobiology, Duke University, Durham, NC 27710, USA
    Sci Rep 3:1319. 2013
    ....
  11. pmc Learning to control a brain-machine interface for reaching and grasping by primates
    Jose M Carmena
    Department of Neurobiology, Duke University, Durham, North Carolina, USA
    PLoS Biol 1:E42. 2003
    ..Learning to operate the BMIc was paralleled by functional reorganization in multiple cortical areas, suggesting that the dynamic properties of the BMIc were incorporated into motor and sensory cortical representations...
  12. pmc Computing with thalamocortical ensembles during different behavioural states
    Miguel A L Nicolelis
    Department of Neurology, Center for Neuroengineering, Box 3209, Room 327 Bryan Research Building, Duke University, Durham, NC 27710, USA
    J Physiol 566:37-47. 2005
    ....
  13. doi request reprint Principles of neural ensemble physiology underlying the operation of brain-machine interfaces
    Miguel A L Nicolelis
    Duke University Center for Neuroengineering and the Department of Neurobiology, Duke University, Durham, North Carolina 27710, USA
    Nat Rev Neurosci 10:530-40. 2009
    ..Further understanding of these principles is likely to have a key role in the future development of neuroprosthetics for restoring mobility in severely paralysed patients...
  14. ncbi request reprint Thalamocortical [correction of Thalamcortical] optimization of tactile processing according to behavioral state
    Miguel A L Nicolelis
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Nat Neurosci 5:517-23. 2002
    ....
  15. pmc Chronic, multisite, multielectrode recordings in macaque monkeys
    Miguel A L Nicolelis
    Department of Neurobiology, Duke University, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 100:11041-6. 2003
    ..This method should benefit neurophysiological investigation of learning, perception, and sensorimotor integration in primates and the development of neuroprosthetic devices...
  16. ncbi request reprint Brain-machine interfaces to restore motor function and probe neural circuits
    Miguel A L Nicolelis
    Department of Neurobiology, Box 3209, Bryan Research Building, Room 327E, 101 Research Drive, Duke University Medical Center, Durham, North Carolina 27710, USA
    Nat Rev Neurosci 4:417-22. 2003
  17. ncbi request reprint Multielectrode recordings: the next steps
    Miguel A L Nicolelis
    Department of Neurobiology, Box 3209, Duke University, Durham, North Carolina 27710, USA
    Curr Opin Neurobiol 12:602-6. 2002
    ..Current methods of multielectrode recording employ state of the art technologies; two potential new avenues of research will likely emerge from the further development of these experimental paradigms...
  18. pmc Dynamic shifting in thalamocortical processing during different behavioural states
    Miguel A L Nicolelis
    Department of Neurobiology and Duke Centre for Neuroengineering, Duke University Medical Center, Durham, NC 27710, USA
    Philos Trans R Soc Lond B Biol Sci 357:1753-8. 2002
    ....
  19. doi request reprint Food reward in the absence of taste receptor signaling
    Ivan E de Araujo
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Neuron 57:930-41. 2008
    ..Our findings suggest that calorie-rich nutrients can directly influence brain reward circuits that control food intake independently of palatability or functional taste transduction...
  20. ncbi request reprint Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction
    Rui M Costa
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Neuron 52:359-69. 2006
    ..Thus, dopamine-related disorders like Parkinson's disease may not stem from changes in the overall levels of cortical activity, but from dysfunctional activity coordination in corticostriatal circuits...
  21. ncbi request reprint Cortical ensemble adaptation to represent velocity of an artificial actuator controlled by a brain-machine interface
    Mikhail A Lebedev
    Department of Neurobiology, Duke University, Durham, North Carolina 27710, USA
    J Neurosci 25:4681-93. 2005
    ..These results show that, during BMI control, cortical ensembles represent behaviorally significant motor parameters, even if these are not associated with movements of the animal's own limb...
  22. ncbi request reprint Seeking the neural code
    Miguel A L Nicolelis
    Duke University, USA
    Sci Am 295:70-7. 2006
  23. ncbi request reprint Optimizing a linear algorithm for real-time robotic control using chronic cortical ensemble recordings in monkeys
    Johan Wessberg
    Duke University, USA
    J Cogn Neurosci 16:1022-35. 2004
    ....
  24. pmc Behavioral and neural responses to gustatory stimuli delivered non-contingently through intra-oral cannulas
    Ernesto S Soares
    Department of Neurobiology, Duke University, Durham, NC, USA
    Physiol Behav 92:629-42. 2007
    ..We posit that these tuning changes arise, at least in part, from compounds released upon ingestion, and also from differences in areas of the oral cavity that are bathed as the animals ingest or reject the tastants...
  25. ncbi request reprint Behavioral detection of tactile stimuli during 7-12 Hz cortical oscillations in awake rats
    Michael C Wiest
    Department of Neurobiology, Box 3209, Duke Medical Center, Durham, North Carolina 27710, USA
    Nat Neurosci 6:913-4. 2003
    ..They responded rapidly and reliably, suggesting that this brain rhythm represents normal physiological activity that does not preclude perception...
  26. ncbi request reprint Frontal and parietal cortical ensembles predict single-trial muscle activity during reaching movements in primates
    David M Santucci
    Department of Neurobiology, Box 3209, Duke University Medical Center, 101 Research Drive, Room 327E, Durham, NC 27710, USA
    Eur J Neurosci 22:1529-40. 2005
    ..We propose that, in the future, recordings from multiple cortical areas and the extraction of muscle patterns from these recordings will help to restore limb mobility in paralysed patients...
  27. ncbi request reprint Neuronal activity in the primary somatosensory thalamocortical loop is modulated by reward contingency during tactile discrimination
    Janaina Pantoja
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 27:10608-20. 2007
    ..Together, our results indicate that neuronal activity in the primary somatosensory thalamocortical loop is strongly modulated by reward contingency...
  28. doi request reprint Three-dimensional, automated, real-time video system for tracking limb motion in brain-machine interface studies
    Ian D Peikon
    Department of Biomedical Engineering, Center for Neuroengineering, Duke University, Durham, NC 27710, USA
    J Neurosci Methods 180:224-33. 2009
    ..We propose that this system could also be extended to applications that include other classes of biological motion...
  29. ncbi request reprint Dopaminergic control of sleep-wake states
    Kafui Dzirasa
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 26:10577-89. 2006
    ..We propose that psychosis and the sleep disturbances experienced by Parkinsonian patients result from dopamine-mediated disturbances of REM sleep...
  30. ncbi request reprint Ensemble recordings of human subcortical neurons as a source of motor control signals for a brain-machine interface
    Parag G Patil
    Division of Neurosurgery, Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Neurosurgery 55:27-35; discussion 35-8. 2004
    ..Here, we report an implementation of this strategy in the human intraoperative setting to assess the feasibility of using neurons in subcortical motor areas to drive a human brain-machine interface...
  31. pmc Licking-induced synchrony in the taste-reward circuit improves cue discrimination during learning
    Ranier Gutierrez
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 30:287-303. 2010
    ....
  32. pmc Taste-guided decisions differentially engage neuronal ensembles across gustatory cortices
    Christopher J MacDonald
    Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708, USA
    J Neurosci 29:11271-82. 2009
    ..These results indicate that during a taste-guided decision task both primary and secondary gustatory cortices dynamically encode different types of information...
  33. ncbi request reprint Stable ensemble performance with single-neuron variability during reaching movements in primates
    Jose M Carmena
    Department of Neurobiology, Center for Neuroengineering, Duke University, Durham, North Carolina 27710, USA
    J Neurosci 25:10712-6. 2005
    ....
  34. ncbi request reprint Depression at thalamocortical synapses: the key for cortical neuronal adaptation?
    Miguel A L Nicolelis
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Neuron 34:331-2. 2002
    ..In this issue of Neuron, Chung et al. provide conclusive evidence that depression of thalamocortical synapses may play a significant role in the expression of neuronal adaptation in the rat somatosensory cortex...
  35. ncbi request reprint Decoding of temporal intervals from cortical ensemble activity
    Mikhail A Lebedev
    Deptartment of Neurobiology, Duke Univiversity, Durham, North Carolina 27100, USA
    J Neurophysiol 99:166-86. 2008
    ..We suggest that decoding of temporal intervals from bilaterally recorded cortical ensembles could improve the performance of neural prostheses for restoration of motor function...
  36. pmc Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony
    Kafui Dzirasa
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 30:6387-97. 2010
    ....
  37. pmc Spatiotemporal coupling between hippocampal acetylcholine release and theta oscillations in vivo
    Hao Zhang
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 30:13431-40. 2010
    ..These findings also suggest that phasic ACh is not required for theta initiation and may instead operate synergistically with theta oscillations to promote neural plasticity in the service of learning and memory...
  38. pmc Restoration of locomotive function in Parkinson's disease by spinal cord stimulation: mechanistic approach
    Romulo Fuentes
    Department of Neurobiology, Duke Medical Center, 311 Research Drive, Durham, NC 27710, USA
    Eur J Neurosci 32:1100-8. 2010
    ....
  39. pmc Neuronal ensemble bursting in the basal forebrain encodes salience irrespective of valence
    Shih Chieh Lin
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Neuron 59:138-49. 2008
    ....
  40. pmc A fully implantable 96-channel neural data acquisition system
    MICHAEL RIZK
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    J Neural Eng 6:026002. 2009
    ..This demonstration of a high channel-count fully implanted neural data acquisition system is a critical step in the development of a clinically viable brain-machine interface...
  41. pmc Spinal cord stimulation restores locomotion in animal models of Parkinson's disease
    Romulo Fuentes
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Science 323:1578-82. 2009
    ..We propose that dorsal column stimulation might become an efficient and less invasive alternative for treatment of Parkinson's disease in the future...
  42. pmc Chronic in vivo multi-circuit neurophysiological recordings in mice
    Kafui Dzirasa
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    J Neurosci Methods 195:36-46. 2011
    ..Thus, our approach provides a powerful tool that will aid in dissecting the central brain network changes that underlie the complex behavioral deficits displayed by various genetically modified mice...
  43. pmc Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling
    Kafui Dzirasa
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 29:8215-24. 2009
    ....
  44. pmc Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania
    Kafui Dzirasa
    Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 30:16314-23. 2010
    ....
  45. pmc Acquiring local field potential information from amperometric neurochemical recordings
    Hao Zhang
    Dept of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    J Neurosci Methods 179:191-200. 2009
    ..As such, our findings provide the first demonstration that both LFP and local neurochemical information can be simultaneously acquired from electrochemical sensors alone...
  46. ncbi request reprint Transmission latencies in a telemetry-linked brain-machine interface
    Chad A Bossetti
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    IEEE Trans Biomed Eng 51:919-24. 2004
    ..A comparison of neuron firing rate and resulting latencies shows that high latencies result from neuron bursting. These results will impact the design of transcutaneous telemetry in a BMI...
  47. ncbi request reprint Taste-specific neuronal ensembles in the gustatory cortex of awake rats
    Donald B Katz
    Department of Neurobiology, Duke University, Durham, North Carolina 27710, USA
    J Neurosci 22:1850-7. 2002
    ..These data suggest that taste-specific GC assemblies may transiently form and coevolve on a behaviorally appropriate timescale, contributing to rats' ability to discriminate tastants...
  48. ncbi request reprint Heterogeneous integration of bilateral whisker signals by neurons in primary somatosensory cortex of awake rats
    Michael C Wiest
    Department of Neurobiology, Duke University Medical Center, 101 Research Drive, Durham, NC 27710, USA
    J Neurophysiol 93:2966-73. 2005
    ....
  49. ncbi request reprint Differential corticostriatal plasticity during fast and slow motor skill learning in mice
    Rui M Costa
    Department of Neurobiology, Duke University Medical Center, Box 3209, Durham, NC 27710, USA
    Curr Biol 14:1124-34. 2004
    ..However, the nature and dynamics of the plastic changes in each of these brain structures during the different phases of motor learning remain unclear...
  50. ncbi request reprint Layer-specific somatosensory cortical activation during active tactile discrimination
    David J Krupa
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Science 304:1989-92. 2004
    ..Instead, these results suggest that top-down influences during active discrimination may alter the overall functional nature of SI as well as layer-specific mechanisms of tactile processing...
  51. ncbi request reprint Reduction of single-neuron firing uncertainty by cortical ensembles during motor skill learning
    Dana Cohen
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 24:3574-82. 2004
    ....
  52. ncbi request reprint A multichannel telemetry system for single unit neural recordings
    Iyad Obeid
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    J Neurosci Methods 133:33-8. 2004
    ..The device was successfully used to record signals from awake, chronically implanted macaque and owl monkeys...
  53. ncbi request reprint A low power multichannel analog front end for portable neural signal recordings
    Iyad Obeid
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    J Neurosci Methods 133:27-32. 2004
    ..The described circuit is light weight and low power and is used as a component of a wearable multichannel neural telemetry system...
  54. pmc Long-lasting novelty-induced neuronal reverberation during slow-wave sleep in multiple forebrain areas
    Sidarta Ribeiro
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA
    PLoS Biol 2:E24. 2004
    ....
  55. ncbi request reprint Two multichannel integrated circuits for neural recording and signal processing
    Iyad Obeid
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    IEEE Trans Biomed Eng 50:255-8. 2003
    ..Those on Device B had mean gains of 53.4 and 47.4 dB with a high-pass filter pole at 211 Hz and an equivalent input noise of 4.4 microV(rms). Both devices were tested in vivo with electrode arrays implanted in the somatosensory cortex...
  56. ncbi request reprint Gustatory processing is dynamic and distributed
    Donald B Katz
    Volen Center for Complex Systems, Department of Psychology, Brandeis University, MS 062, Waltham, MA 02454 9110, USA
    Curr Opin Neurobiol 12:448-54. 2002
    ..We propose that the specifics of gustatory responses grow not only out of information ascending from taste receptor cells, but also from the cycling of information around a massively interconnected system...
  57. pmc Reverberation, storage, and postsynaptic propagation of memories during sleep
    Sidarta Ribeiro
    Department of Neurobiology, Duke University Medical Center, Duke University, Durham, North Carolina 27710, USA
    Learn Mem 11:686-96. 2004
    ....
  58. ncbi request reprint Global forebrain dynamics predict rat behavioral states and their transitions
    Damien Gervasoni
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 24:11137-47. 2004
    ....
  59. ncbi request reprint Gustatory effects of capsaicin that are independent of TRPV1 receptors
    Rui M Costa
    Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA
    Chem Senses 30:i198-200. 2005
  60. ncbi request reprint The neural mechanisms of gustation: a distributed processing code
    Sidney A Simon
    Department of Neurobiology, Duke University, Durham, North Carolina 27710, USA
    Nat Rev Neurosci 7:890-901. 2006
    ..On the basis of recent experimental data, we argue that these brain circuits make use of distributed ensemble codes that represent the sensory and post-ingestive properties of tastants...
  61. ncbi request reprint Fast modulation of prefrontal cortex activity by basal forebrain noncholinergic neuronal ensembles
    Shih Chieh Lin
    Department of Neurobiology, Duke University Medical Center, 101 Research Drive, Box 3209, Durham, NC 27710, USA
    J Neurophysiol 96:3209-19. 2006
    ....
  62. ncbi request reprint Neural ensemble coding of satiety states
    Ivan E de Araujo
    Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Neuron 51:483-94. 2006
    ..This distributed population code might constitute a neural mechanism underlying meal initiation under different metabolic states...
  63. ncbi request reprint Brain-machine interfaces: past, present and future
    Mikhail A Lebedev
    Department of Neurobiology and Center for Neuroengineering, Duke University, Durham, NC 27710, USA
    Trends Neurosci 29:536-46. 2006
    ..By reaching these milestones, future BMIs will be able to drive and control revolutionary prostheses that feel and act like the human arm...
  64. ncbi request reprint Rapid taste responses in the gustatory cortex during licking
    Jennifer R Stapleton
    Department of Neurobiology, Duke University, Durham, North Carolina 27710, USA
    J Neurosci 26:4126-38. 2006
    ....
  65. ncbi request reprint Orbitofrontal ensemble activity monitors licking and distinguishes among natural rewards
    Ranier Gutierrez
    Department of Neurobiology, Duke University Medical Center, Bryan Research Bldg, Durham, NC 27710, USA
    J Neurophysiol 95:119-33. 2006
    ..These results provide a new role for the OFC in influencing licking clusters and anticipating specific rewards...
  66. ncbi request reprint Interval timing and the encoding of signal duration by ensembles of cortical and striatal neurons
    Matthew S Matell
    Department of Psychological and Brain Sciences, Duke University, USA
    Behav Neurosci 117:760-73. 2003
    ..Results suggest that striatal and cortical neurons encode specific durations in their firing rate and thereby serve as components of a neural circuit used to represent duration...
  67. pmc Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors
    Georgia M Alexander
    Department of Neurobiology, Duke University, Durham, NC 27710, USA
    Neuron 63:27-39. 2009
    ..These results demonstrate a powerful chemical-genetic tool for remotely controlling the activity of discrete populations of neurons in vivo...
  68. ncbi request reprint Ascertaining the importance of neurons to develop better brain-machine interfaces
    Justin C Sanchez
    Department of Biomedical Engineering, University of Florida, Room EB 454, Gainesville, FL 32611, USA
    IEEE Trans Biomed Eng 51:943-53. 2004
    ....
  69. ncbi request reprint Controlling robots with the mind
    Miguel A L Nicolelis
    Sci Am 287:46-53. 2002
  70. ncbi request reprint Interpreting spatial and temporal neural activity through a recurrent neural network brain-machine interface
    Justin C Sanchez
    Department of Pediatrics Division of Neurology, University of Florida, Gainesville, FL 32611, USA
    IEEE Trans Neural Syst Rehabil Eng 13:213-9. 2005
    ..Next, using the trained model weights, we derive a temporal sensitivity measure to asses how the model utilized the sampled cortices and neurons in real-time during BMI testing...
  71. ncbi request reprint Continuous shared control for stabilizing reaching and grasping with brain-machine interfaces
    Hyun K Kim
    Touch Laboratory, Massachusetts Institute of Technology, Cambridge 02139, USA
    IEEE Trans Biomed Eng 53:1164-73. 2006
    ..Such a marked performance improvement in this test case suggests that some level of machine autonomy will be an important component of successful BMI systems in general...
  72. ncbi request reprint Integration of bilateral whisker stimuli in rats: role of the whisker barrel cortices
    Marshall G Shuler
    Department of Neuroscience, 190 Thayer Street, HHMI Brown University, Providence, RI 02912, USA
    Cereb Cortex 12:86-97. 2002
    ..The findings presented here indicate that rats can solve a task that requires the conjoint detection of left and right whisker-mediated distance information and implicate the SIws as central to this ability...
  73. pmc Processing of tactile information by the hippocampus
    Antonio Pereira
    Departamento de Fisiologia, Universidade Federal do Para, PA 66075 900, Belem, Brazil
    Proc Natl Acad Sci U S A 104:18286-91. 2007
    ..Taken together, our results show that tactile information associated with fine whisker discrimination is readily available to the hippocampus for dynamic updating of spatial maps...
  74. ncbi request reprint The muscle activation method: an approach to impedance control of brain-machine interfaces through a musculoskeletal model of the arm
    Hyun K Kim
    Mechatronics and Manufacturing Technology Center, Samsung Electronics, Suwon, Korea
    IEEE Trans Biomed Eng 54:1520-9. 2007
    ..Furthermore, it successfully predicted limb interactions with novel force fields, which is a new and significant capability lacking in other algorithms...

Research Grants27

  1. TRIGEMINAL SYSTEM PLASTICITY DURING FACIAL ANESTHESIA
    Miguel Nicolelis; Fiscal Year: 2002
    ....
  2. Corticofugal Modulation of Tactile Sensory Processing
    Miguel Nicolelis; Fiscal Year: 2001
    ..abstract_text> ..
  3. TRIGEMINAL SYSTEM PLASTICITY DURING FACIAL ANESTHESIA
    Miguel Nicolelis; Fiscal Year: 2001
    ....
  4. Trigeminal System Plasticity During Active Exploration
    Miguel Nicolelis; Fiscal Year: 2009
    ..abstract_text> ..
  5. Corticofugal Modulation of Tactile Sensory Processing
    Miguel Nicolelis; Fiscal Year: 2002
    ..abstract_text> ..
  6. Trigeminal System Plasticity During Active Exploration
    Miguel Nicolelis; Fiscal Year: 2009
    ..abstract_text> ..
  7. Corticofugal Modulation of Tactile Sensory Processing
    Miguel Nicolelis; Fiscal Year: 2005
    ..abstract_text> ..
  8. Trigeminal System Plasticity During Active Exploration
    Miguel Nicolelis; Fiscal Year: 2007
    ....
  9. TRIGEMINAL SYSTEM PLASTICITY DURING FACIAL ANESTHESIA
    Miguel Nicolelis; Fiscal Year: 2000
    ....
  10. TRIGEMINAL SYSTEM PLASTICITY DURING FACIAL ANESTHESIA
    Miguel Nicolelis; Fiscal Year: 1999
    ....
  11. Trigeminal System Plasticity During Active Exploration
    Miguel A L Nicolelis; Fiscal Year: 2010
    ..abstract_text> ..
  12. Method for In-Vivo Assessment of Neuronal Dysfunction
    Miguel Nicolelis; Fiscal Year: 2007
    ....
  13. Corticofugal Modulation of Tactile Sensory Processing
    Miguel Nicolelis; Fiscal Year: 2004
    ..abstract_text> ..
  14. Corticofugal Modulation of Tactile Sensory Processing
    Miguel Nicolelis; Fiscal Year: 2003
    ..abstract_text> ..
  15. Dorsal Column Stimulation as a New Therapy for Motor Disorders
    Miguel A L Nicolelis; Fiscal Year: 2010
    ....
  16. GNE 2007: Global NeuroEngineering 2007
    Miguel Nicolelis; Fiscal Year: 2007
    ....