Judd W Moul

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Variables in predicting survival based on treating "PSA-only" relapse
    Judd W Moul
    Department of Surgery, Urology Service, Walter Reed Army Medical Center, Washington, DC, USA
    Urol Oncol 21:292-304. 2003
  2. doi request reprint Focusing on testosterone
    Judd W Moul
    Department of Surgery, Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 78:S476-7. 2011
  3. ncbi request reprint NADiA ProsVue prostate-specific antigen slope is an independent prognostic marker for identifying men at reduced risk of clinical recurrence of prostate cancer after radical prostatectomy
    Judd W Moul
    Division of Urologic Surgery and Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 80:1319-25. 2012
  4. doi request reprint Quality of life associated with treatment of castration-resistant prostate cancer: a review of the literature
    Judd W Moul
    Division of Urologic Surgery and Duke Prostate Center, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina 22710, USA
    Cancer Invest 30:1-12. 2012
  5. ncbi request reprint Age adjusted prostate specific antigen and prostate specific antigen velocity cut points in prostate cancer screening
    Judd W Moul
    Division of Urology and Duke Prostate Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 177:499-503; discussion 503-4. 2007
  6. ncbi request reprint Treatment of PSA only recurrence of prostate cancer after prior local therapy
    Judd W Moul
    Division of Urologic Surgery and Duke Prostate Center, Duke University Medical Center, DUMC 3707, Durham, NC 27710, USA
    Curr Pharm Des 12:785-98. 2006
  7. ncbi request reprint Hormonal therapy options for prostate-specific antigen-only recurrence of prostate cancer after previous local therapy
    Judd W Moul
    Division of Urologic Surgery and Duke Prostate Cancer, Duke University, Durham, NC 27710, USA
    BJU Int 95:285-90. 2005
  8. ncbi request reprint Rising PSA in nonmetastatic prostate cancer
    Judd W Moul
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    Oncology (Williston Park) 21:1436-45; discussion 1449, 1452, 1454. 2007
  9. ncbi request reprint Management of the patient with a rising PSA alone
    Judd W Moul
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Duke South, Durham, NC 27710, USA
    Hematol Oncol Clin North Am 20:897-908. 2006
  10. doi request reprint Post-radical prostatectomy management options for positive surgical margins: argument for observation
    Judd W Moul
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    Urol Oncol 27:92-6. 2009

Collaborators

Detail Information

Publications117 found, 100 shown here

  1. ncbi request reprint Variables in predicting survival based on treating "PSA-only" relapse
    Judd W Moul
    Department of Surgery, Urology Service, Walter Reed Army Medical Center, Washington, DC, USA
    Urol Oncol 21:292-304. 2003
    ..Early work would suggest that timing of recurrence, Gleason grade, and PSA velocity or doubling time during relapse are important prognostic factors. New data on PSA doubling time will be presented...
  2. doi request reprint Focusing on testosterone
    Judd W Moul
    Department of Surgery, Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 78:S476-7. 2011
    ..However, during the past 30 years, newer agents that lower serum testosterone even more effectively have been approved and the indications for use of these newer agents re-evaluated...
  3. ncbi request reprint NADiA ProsVue prostate-specific antigen slope is an independent prognostic marker for identifying men at reduced risk of clinical recurrence of prostate cancer after radical prostatectomy
    Judd W Moul
    Division of Urologic Surgery and Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 80:1319-25. 2012
    ....
  4. doi request reprint Quality of life associated with treatment of castration-resistant prostate cancer: a review of the literature
    Judd W Moul
    Division of Urologic Surgery and Duke Prostate Center, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina 22710, USA
    Cancer Invest 30:1-12. 2012
    ..The review also provides a narrative description of the evolving role of quality of life measures in clinical trials, and critiques the most widely used instruments...
  5. ncbi request reprint Age adjusted prostate specific antigen and prostate specific antigen velocity cut points in prostate cancer screening
    Judd W Moul
    Division of Urology and Duke Prostate Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 177:499-503; discussion 503-4. 2007
    ..We identified age adjusted prostate specific antigen and prostate specific antigen velocity cut points for prostate cancer biopsy...
  6. ncbi request reprint Treatment of PSA only recurrence of prostate cancer after prior local therapy
    Judd W Moul
    Division of Urologic Surgery and Duke Prostate Center, Duke University Medical Center, DUMC 3707, Durham, NC 27710, USA
    Curr Pharm Des 12:785-98. 2006
    ..This monograph will attempt to provide a complete balanced discussion of the evaluation and treatment of biochemical recurrence of prostate cancer after prior primary local therapy...
  7. ncbi request reprint Hormonal therapy options for prostate-specific antigen-only recurrence of prostate cancer after previous local therapy
    Judd W Moul
    Division of Urologic Surgery and Duke Prostate Cancer, Duke University, Durham, NC 27710, USA
    BJU Int 95:285-90. 2005
  8. ncbi request reprint Rising PSA in nonmetastatic prostate cancer
    Judd W Moul
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    Oncology (Williston Park) 21:1436-45; discussion 1449, 1452, 1454. 2007
    ..In this article, we will explore these prostate cancer disease states with an emphasis on practical, clinically applicable approaches...
  9. ncbi request reprint Management of the patient with a rising PSA alone
    Judd W Moul
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Duke South, Durham, NC 27710, USA
    Hematol Oncol Clin North Am 20:897-908. 2006
    ..More clinical trials are needed to determine the best treatments, alone and in combination. The potential opportunities for novel therapeutic agents with low associated morbidity are great...
  10. doi request reprint Post-radical prostatectomy management options for positive surgical margins: argument for observation
    Judd W Moul
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    Urol Oncol 27:92-6. 2009
    ..The first episode to potentially deflate his sails is when the surgical pathology report returns and shows a positive margin...
  11. ncbi request reprint Timely diagnosis of testicular cancer
    Judd W Moul
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC, USA
    Urol Clin North Am 34:109-17; abstract vii. 2007
    ..Although screening on a population basis is not currently recommended by the National Cancer Institute, teaching testicular self examination to young men, particularly those who have risk factors, is reasonable...
  12. ncbi request reprint Prostate cancer: the new landscape
    Judd W Moul
    Division of Urologic Surgery and Duke Prostate Center DPC, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Curr Opin Urol 19:154-60. 2009
    ..This review highlights current features of the changing landscape of the US population with newly diagnosed prostate cancer and discusses new treatment options utilizing noninvasive or minimally invasive management...
  13. doi request reprint Factors predicting prostatic biopsy Gleason sum under grading
    Danielle A Stackhouse
    Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 182:118-22; discussion 123-4. 2009
    ..We determined clinical factors affecting the under grading of biopsy Gleason sum compared with prostatectomy pathology and developed a model predicting the probability of under grading...
  14. pmc Postoperative prostate-specific antigen nadir improves accuracy for predicting biochemical recurrence after radical prostatectomy: Results from the Shared Equal Access Regional Cancer Hospital (SEARCH) and Duke Prostate Center databases
    Daniel M Moreira
    Division of Urologic Surgery, Department of Surgery, Duke Prostate Center Department of Pathology, Duke University School of Medicine Urology Section, Veterans Affairs Medical Center, Durham, North Carolina, USA
    Int J Urol 17:914-22. 2010
    ..Herein, we sought to explore the effect of including PSA nadir into commonly used models on their accuracy to predict BCR after RP...
  15. ncbi request reprint Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line
    Yongpeng Gu
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Anticancer Res 25:1-8. 2005
    ..NKX 3.1 and epithelial cell specific cytokeratin 8, androgen receptor (AR), prostate stem cell antigen and p16, but not PSA. AR protein was detected by Western blot analysis...
  16. doi request reprint Association between preoperative erectile dysfunction and prostate cancer features--an analysis from the Duke Prostate Center Database
    Masaki Kimura
    Division of Urologic Surgery, Department of Surgery, Duke Prostate Center, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA
    J Sex Med 9:1174-81. 2012
    ..Erectile dysfunction (ED) is related to several co-morbidities including obesity, metabolic syndrome, cigarette smoking, and low testosterone, all of which have been reported to be associated with adverse prostate cancer features...
  17. doi request reprint Pretreatment expectations of patients undergoing robotic assisted laparoscopic or open retropubic radical prostatectomy
    Florian R Schroeck
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 187:894-8. 2012
    ..In the current study we compared expectations of patients undergoing robotic assisted laparoscopic radical prostatectomy vs radical retropubic prostatectomy...
  18. ncbi request reprint A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes
    Yongpeng Gu
    Center for Prostate Disease Research, Department of Surgery, Uniformed Service University of Health Sciences, Bethesda, MD 20814, USA
    Int J Oncol 25:1057-64. 2004
    ..This is the first documented case of an AR and PSA expressing telomerase established human prostate cancer cell line with neoplastic phenotypes from a primary tumor of a prostate cancer patient...
  19. ncbi request reprint A novel neoplastic primary tumor-derived human prostate epithelial cell line
    Daejin Ko
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Int J Oncol 22:1311-7. 2003
    ..This is the first documented case of a malignant AR and PSA positive established human prostate cancer cell line from a primary tumor of a prostate cancer patient...
  20. ncbi request reprint Biochemical recurrence after definitive prostate cancer therapy. Part II: treatment strategies for biochemical recurrence of prostate cancer
    John F Ward
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Curr Opin Urol 15:187-95. 2005
    ..Such prostate-specific antigen relapses, conservatively estimated to affect approximately 50 000 men each year, have become the most common form of advanced prostate cancer in the current period...
  21. doi request reprint Preoperative predictors of pathologic stage T2a in low-risk prostate cancer: implications for focal therapy
    Qiang Fu
    Division of Urology, Department of Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    Urol Int 89:296-300. 2012
    ..To assess preoperative parameters that may be predictive of pathologic stage T2a disease in low-risk prostate cancer patients...
  22. ncbi request reprint PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression
    Linda L Xu
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, 1530 East Jefferson Street, Bethesda, MD 20852, USA
    Cancer Res 63:4299-304. 2003
    ..Loss or reduced PMEPA1 expression in CaP further suggests for its role in prostate tumorigenesis...
  23. doi request reprint Body mass index and prostate specific antigen as predictors of adverse pathology and biochemical recurrence after prostatectomy
    Lionel L Banez
    Department of Surgery Division of Urologic Surgery and Duke Prostate Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 182:491-6; discussion 496-8. 2009
    ..We determined whether the clinical usefulness of prostate specific antigen is negatively impacted by obesity by examining its operating characteristics and predictive accuracy as a function of body mass index...
  24. doi request reprint Percent tumor involvement and risk of biochemical progression after radical prostatectomy
    Edward N Rampersaud
    Division of Urologic Surgery, Duke Prostate Center, Durham, North Carolina, USA
    J Urol 180:571-6; discussion 576. 2008
    ..We hypothesized percent tumor involvement may be a good correlate of outcome in all stages of prostate cancer...
  25. doi request reprint Initial prostate specific antigen 1.5 ng/ml or greater in men 50 years old or younger predicts higher prostate cancer risk
    Ping Tang
    Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 183:946-50. 2010
    ..Studies show that initial prostate specific antigen higher than the median in young men predicts a subsequent higher risk of prostate cancer. To our knowledge this relationship has not been studied in patients stratified by race...
  26. doi request reprint Re-calibration and external validation of an existing nomogram to predict aggressive recurrences after radical prostatectomy
    Florian R Schroeck
    Division of Urologic Surgery, Department of Surgery, and Duke Prostate Center, Duke University School of Medicine, Durham, NC 27710, USA
    BJU Int 105:1654-9. 2010
    ..e. a BCR with a postoperative PSA doubling time (PSADT) of <9 months)...
  27. doi request reprint Predicting participation in and successful outcome of a penile rehabilitation programme using a phosphodiesterase type 5 inhibitor with a vacuum erection device after radical prostatectomy
    Masaki Kimura
    Division of Urologic Surgery, Department of Surgery and Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    BJU Int 110:E931-8. 2012
    ..Notably, there was a primary surgeon difference, which had a trend for predicting outcome of the rehabilitation among the participants, implying their surgical technique and follow-up might influence success of the rehabilitation...
  28. ncbi request reprint Pretreatment total testosterone level predicts pathological stage in patients with localized prostate cancer treated with radical prostatectomy
    Jason C Massengill
    Department of Surgery, Center for Prostatic Disease Research, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    J Urol 169:1670-5. 2003
    ..We rigorously tested pretreatment total testosterone levels as a potential staging and prognostic marker in a large cohort of 879 patients with localized cancer treated with radical prostatectomy...
  29. doi request reprint Public survey and survival data do not support recommendations to discontinue prostate-specific antigen screening in men at age 75
    Arthur A Caire
    Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Urology 75:1122-7. 2010
    ..To evaluate the US Preventative Services Task Force (USPSTF) recommendation to discontinue prostate-specific antigen (PSA) screening at age 75...
  30. doi request reprint Obesity and oncological outcome after radical prostatectomy: impact of prostate-specific antigen-based prostate cancer screening: results from the Shared Equal Access Regional Cancer Hospital and Duke Prostate Center databases
    Stephen J Freedland
    Urology Section, Department of Surgery, Veterans Affairs Medical Center, Duke University Medical Center, Durham, NC 27710, USA
    BJU Int 102:969-74. 2008
    ....
  31. ncbi request reprint Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy
    Judd W Moul
    Department of Surgery, Uniformed Services University of the Health Sciences, National Naval Medical Center, Bethesda 20852, USA
    J Urol 171:1141-7. 2004
    ....
  32. doi request reprint A retrospective comparison of anesthetic management of robot-assisted laparoscopic radical prostatectomy versus radical retropubic prostatectomy
    Richard C D'Alonzo
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 21:322-8. 2009
    ..To compare anesthetic management and postoperative outcomes in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP) and radical retropubic prostatectomy (RRP) with general anesthesia...
  33. doi request reprint Tumor percent involvement predicts prostate specific antigen recurrence after radical prostatectomy only in men with smaller prostate
    Matthew A Uhlman
    Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 183:997-1001. 2010
    ..We determined the predictive power of tumor percent involvement on prostate specific antigen recurrence in patients when stratified by prostate weight...
  34. doi request reprint Pathologic stage T2a and T2b prostate cancer in the recent prostate-specific antigen era: implications for unilateral ablative therapy
    Thomas J Polascik
    Duke Prostate Center and Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Prostate 68:1380-6. 2008
    ..We evaluated trends in pathologic staging among patients with localized PCa undergoing radical prostatectomy (RP), defining the frequency of unilateral cancers during 1988-1995, 1996-2000 and 2001-2006...
  35. ncbi request reprint Treating the biochemical recurrence of prostate cancer after definitive primary therapy
    John F Ward
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Clin Prostate Cancer 4:38-44. 2005
    ..The potential opportunities for novel therapeutic agents with low associated morbidity are great...
  36. ncbi request reprint Temporarily deferred therapy (watchful waiting) for men younger than 70 years and with low-risk localized prostate cancer in the prostate-specific antigen era
    Corey A Carter
    Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    J Clin Oncol 21:4001-8. 2003
    ..An analysis of the Department of Defense Center for Prostate Disease Research Database was undertaken to document younger men with low- or intermediate-grade PC who initially chose WW...
  37. doi request reprint Robot-assisted laparoscopic prostatectomy is not associated with early postoperative radiation therapy
    Junzo Chino
    Radiation Oncology, Duke University Medical Center, Durham, NC, USA
    BJU Int 104:1496-500. 2009
    ....
  38. ncbi request reprint Diagnostic potential of prostate-specific antigen expressing epithelial cells in blood of prostate cancer patients
    Chun Ling Gao
    Center for Prostate Disease Research, Department of Surgery, Uniformed Service University of the Health Science, Bethesda, Maryland 20814 4799, USA
    Clin Cancer Res 9:2545-50. 2003
    ....
  39. ncbi request reprint Factors associated with blood loss during radical prostatectomy for localized prostate cancer in the prostate-specific antigen (PSA)-era: an overview of the Department of Defense (DOD) Center for Prostate Disease Research (CPDR) national database
    Judd W Moul
    Urology Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
    Urol Oncol 21:447-55. 2003
    ..In a broad practice experience represented here, autologous blood donation would appear to be unnecessary for the majority of men and the blood loss advantage traditionally associated with perineal RP is no longer evident...
  40. doi request reprint Comparison of prostate-specific antigen recurrence-free survival in a contemporary cohort of patients undergoing either radical retropubic or robot-assisted laparoscopic radical prostatectomy
    Florian R Schroeck
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    BJU Int 102:28-32. 2008
    ..To compare the prostate-specific antigen (PSA) recurrence (PSAR) rates in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP) or radical retropubic prostatectomy (RRP)...
  41. pmc Tumor volume, tumor percentage involvement, or prostate volume: which is predictive of prostate-specific antigen recurrence?
    Matthew A Uhlman
    Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 75:460-6. 2010
    ..To compare the effects of tumor volume (TV), tumor percentage involvement (TPI), and prostate volume (PV) on prostate-specific antigen (PSA) recurrence (PSAR) after radical prostatectomy (RP)...
  42. doi request reprint Combined low-dose flutamide plus finasteride vs low-dose flutamide monotherapy for recurrent prostate cancer: a comparative analysis of two phase II trials with a long-term follow-up
    Lionel L Banez
    Division of Urologic Surgery and the Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    BJU Int 104:310-4. 2009
    ....
  43. ncbi request reprint Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients
    Gyorgy Petrovics
    Department of Surgery, Center for Prostate Disease Research, US Military Cancer Institute, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 4799, USA
    Oncogene 23:605-11. 2004
    ....
  44. doi request reprint Obese African-Americans with prostate cancer (T1c and a prostate-specific antigen, PSA, level of <10 ng/mL) have higher-risk pathological features and a greater risk of PSA recurrence than non-African-Americans
    Arthur A Caire
    Division of Urology, Department of Surgery and Duke Prostate Center, Duke University Medical Center, Durham, North Carolina, USA
    BJU Int 106:1157-60. 2010
    ..to analyse the relationship between African American (AA) race and obesity in men with prostate cancer...
  45. doi request reprint Effect of age and pathologic Gleason score on PSA recurrence: analysis of 2911 patients undergoing radical prostatectomy
    David D Xu
    Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    Urology 74:654-8. 2009
    ..To clarify the relationship between age and pathologic Gleason score and their effect on prostate-specific antigen recurrence (PSAR)...
  46. doi request reprint Prostate-specific antigen-based risk-adapted discontinuation of prostate cancer screening in elderly African American and Caucasian American men
    Ping Tang
    Division of Urology, Department of Surgery, Duke Prostate Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 76:1058-62. 2010
    ..To evaluate the relationship between initial prostate-specific antigen (PSA) and prostate cancer (PCa) risk in elderly African American (AA) and Caucasian American (CA) men...
  47. ncbi request reprint Predictors of extracapsular extension and positive margins in African American and white men
    Edmond L Paquette
    Urology Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC 20307, USA
    Urol Oncol 21:33-8. 2003
    ....
  48. ncbi request reprint Financial comparative analysis of minimally invasive surgery to open surgery for localized prostate cancer: a single-institution experience
    Vladimir Mouraviev
    Duke Prostate Center and Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 69:311-4. 2007
    ....
  49. doi request reprint Biopsy accuracy in identifying unilateral prostate cancer depends on prostate weight
    Matvey Tsivian
    Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Urol Oncol 30:21-5. 2012
    ..To evaluate the association between prostate weight and the diagnostic performance of routine biopsy schemes in detecting unilateral prostate cancer (PCa) that may be amenable to focal therapy...
  50. doi request reprint Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy
    Masaki Kimura
    Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Sex Med 8:2935-43. 2011
    ..Moreover, factors that predict either early or late sexual HRQoL decline have not been fully investigated...
  51. ncbi request reprint Watchful waiting and factors predictive of secondary treatment of localized prostate cancer
    Hongyan Wu
    Department of Surgery, Center for Prostate Disease Research, Uniformed Services University of the Health Sciences, National Naval Medical Center, Bethesda, MD, USA
    J Urol 171:1111-6. 2004
    ..We defined the demographic, clinical and outcome features of men selecting watchful waiting as an initial treatment strategy, and determined factors predictive of eventual progression to secondary treatment...
  52. doi request reprint Patient selection for hemiablative focal therapy of prostate cancer: variables predictive of tumor unilaterality based upon radical prostatectomy
    Thomas J Polascik
    Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Cancer 115:2104-10. 2009
    ..No definitive criteria existed to characterize patients who may potentially benefit from an organ-sparing approach. We evaluated pretreatment clinical parameters that may predict unilateral PCa amenable to hemigland thermoablation...
  53. doi request reprint Satisfaction and regret after open retropubic or robot-assisted laparoscopic radical prostatectomy
    Florian R Schroeck
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Eur Urol 54:785-93. 2008
    ..To counsel patients adequately, it is important to understand the variables influencing satisfaction and regret following prostatectomy...
  54. doi request reprint Delayed prostate-specific antigen recurrence after radical prostatectomy: how to identify and what are their clinical outcomes?
    Arthur A Caire
    Division of Urology, Duke University Medical Center, Durham, NC 27710, USA
    Urology 74:643-7. 2009
    ..To identify factors that predict delayed (> 5 years) prostate-specific antigen recurrence (PSAR) after radical prostatectomy (RP) and to analyze the associated clinical outcomes...
  55. doi request reprint Changes in Gleason score grading and their effect in predicting outcome after radical prostatectomy
    Matvey Tsivian
    Division of Urology, Department of Surgery, Duke Prostate Center, Durham, North Carolina, USA
    Urology 74:1090-3. 2009
    ....
  56. doi request reprint Phase 1 trial of neoadjuvant radiation therapy before prostatectomy for high-risk prostate cancer
    Bridget F Koontz
    Department of Radiation Oncology, Duke Cancer Institute, Durham, North Carolina, USA
    Int J Radiat Oncol Biol Phys 87:88-93. 2013
    ..To evaluate, in a phase 1 study, the safety of neoadjuvant whole-pelvis radiation therapy (RT) administered immediately before radical prostatectomy in men with high-risk prostate cancer...
  57. doi request reprint Preoperative predictors of pathologic stage T2a and pathologic Gleason score ≤ 6 in men with clinical low-risk prostate cancer treated with radical prostatectomy: reference for active surveillance
    Qiang Fu
    Division of Urology, Department of Surgery, Duke Prostate Center, Duke University Medical Center DUMC, Box 2804, Durham, NC 27710, USA
    Med Oncol 30:326. 2013
    ..Unilateral cancer by prostate biopsy and low diagnostic PSA level may be the reference to improving the selection of appropriate candidates for active surveillance within a low-risk prostate cancer cohort...
  58. doi request reprint Role of oxidative stress in a rat model of radiation-induced erectile dysfunction
    Masaki Kimura
    Division of Urologic Surgery, Department of Surgery and Duke Prostate Center, Duke University Medical Center, Durham, NC, USA
    J Sex Med 9:1535-49. 2012
    ..Aims.  To investigate role of oxidative stress after prostate-confined irradiation in a rat model of radiation-induced ED...
  59. doi request reprint Defining potency: a comparison of the International Index of Erectile Function short version and the Expanded Prostate Cancer Index Composite
    Florian R Schroeck
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Cancer 113:2687-94. 2008
    ..In this study, the authors compared various definitions of potency according to the IIEF-5 and the EPIC...
  60. ncbi request reprint p63 expression profile in normal and malignant prostate epithelial cells
    Leland D Davis
    Center for Prostate Disease Research CPDR, Department of Surgery, Uniformed Services University of the Health Sciences, 1530 East Jefferson Street, Rockville, MD 20852, USA
    Anticancer Res 22:3819-25. 2002
    ..The basal cell association underscores its critical functions in the biology of basal cells...
  61. doi request reprint Trainees do not negatively impact the institutional learning curve for robotic prostatectomy as characterized by operative time, estimated blood loss, and positive surgical margin rate
    Florian R Schroeck
    Division of Urologic Surgery and Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 71:597-601. 2008
    ..We evaluated the learning curves and perioperative outcomes of an experienced laparoscopic surgeon and his trainees to assess our structured teaching program...
  62. doi request reprint Significant discrepancies between diagnostic and pathologic Gleason sums in prostate cancer: the predictive role of age and prostate-specific antigen
    Brandon K Isariyawongse
    Division of Urology and Duke Prostate Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 72:882-6. 2008
    ..To assess the discrepancies between diagnostic and pathologic Gleason sums and the predictive role of age and prostate-specific antigen (PSA) level on Gleason sum discrepancies...
  63. pmc External validation of the SEARCH model for predicting aggressive recurrence after radical prostatectomy: results from the Duke Prostate Center Database
    Anna E Teeter
    Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    BJU Int 106:796-800. 2010
    ..79 using a cohort of men from the Duke Prostate Center (DPC)...
  64. doi request reprint Men older than 70 years have higher risk prostate cancer and poorer survival in the early and late prostate specific antigen eras
    Leon Sun
    Division of Urology, Department of Surgery, Duke University Medical Center, Duke Prostate Center, Durham, North Carolina 27710, USA
    J Urol 182:2242-8. 2009
    ..We clarified whether men older than 70 years have a higher risk of prostate cancer and poorer survival in the early and late prostate specific antigen eras...
  65. ncbi request reprint Prostate-specific antigen (PSA) and PSA velocity for prostate cancer detection in men aged <50 years
    Leon Sun
    Division of Urology and Duke Prostate Center, Department of Surgery, Duke University Medical, Center, Durham, NC, USA
    BJU Int 99:753-7. 2007
    ..To identify threshold values of prostate-specific antigen (PSA) levels and PSA velocity (PSAV) to optimize the assessment of the risk of prostate cancer in young men, as prostate cancer is detected increasingly in men aged <50 years...
  66. doi request reprint Baseline PSA as a predictor of prostate cancer-specific mortality over the past 2 decades: Duke University experience
    Ping Tang
    Division of Urology, Department of Surgery and Duke Prostate Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    Cancer 116:4711-7. 2010
    ..Identification of the risk of death from prostate cancer and death from all causes using information available at the time of baseline prostate-specific antigen (PSA) measurement appears to be particularly pertinent...
  67. doi request reprint The Shared Equal Access Regional Cancer Hospital (SEARCH) nomogram for risk stratification in intermediate risk group of men with prostate cancer: validation in the Duke Prostate Center database
    Jayakrishnan Jayachandran
    Division of Urologic Surgery, Department of Surgery, Duke Prostate Center, Duke University School of Medicine, Durham, NC 27710, USA
    BJU Int 105:180-4. 2010
    ....
  68. ncbi request reprint Prostate cancer laterality as a rationale of focal ablative therapy for the treatment of clinically localized prostate cancer
    Vladimir Mouraviev
    Duke Prostate Center and Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Cancer 110:906-10. 2007
    ....
  69. doi request reprint Lidocaine patch for postoperative analgesia after radical retropubic prostatectomy
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical System, Box 3094, Durham, NC 27710, USA
    Anesth Analg 108:1950-3. 2009
    ..0001, time x treatment P = 0.3056) and at rest (17%-32% reduction) for up to 6 h (treatment vs placebo P = 0.0003, time x treatment P = 0.0130)...
  70. ncbi request reprint Molecular markers in prostate cancer: the role in preoperative staging
    Judd W Moul
    Urology Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC, USA
    Clin Prostate Cancer 1:42-50. 2002
    ..Still, this area holds great promise for improving the accuracy of staging and providing a more accurate prognosis of individual men with clinically localized prostate cancer...
  71. doi request reprint Prostate-specific antigen screening among young men in the United States
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Cancer 113:1315-23. 2008
    ..Little is known about the use of PSA testing in these men. To understand policy implications of risk stratification, the authors sought to characterize PSA use among young men...
  72. ncbi request reprint Relationship between body mass index and prostate cancer screening in the United States
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 177:493-8. 2007
    ..To our knowledge the relationship between obesity and prostate cancer screening behavior in men 40 or older is unknown. Thus, we examined associations between body mass index and prostate cancer screening behavior...
  73. doi request reprint Pathological T2 sub-divisions as a prognostic factor in the biochemical recurrence of prostate cancer
    Jorge R Caso
    Division of Urologic Surgery and Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA
    BJU Int 106:1623-7. 2010
    ..To determine the adequacy of T2 prostate cancer (PCa) sub-staging as an independent Predictor of biochemical disease-free survival (bDFS) after radical prostatectomy...
  74. ncbi request reprint Utility of a 3-dimensional transrectal ultrasound-guided prostate biopsy system for prostate cancer detection
    Valerie H Chen
    Duke Prostate Center and Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Technol Cancer Res Treat 8:99-104. 2009
    ..More comprehensive studies are warranted to corroborate and extend the results of this study...
  75. ncbi request reprint Prostate specific antigen recurrence after definitive therapy
    Stephen J Freedland
    Division of Surgery, Durham Veterans Affairs Medical Center, Durham, NC, USA
    J Urol 177:1985-91. 2007
    ..However, to do so the risks and benefits of the various options must be known. Therefore, we provide a comprehensive overview of the natural history and treatment options for men with prostate specific antigen-only recurrence...
  76. ncbi request reprint Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines
    Keiichiro Nakamura
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Int J Oncol 21:825-30. 2002
    ..The results obtained here demonstrate that curcumin has a potential therapeutic effect on prostate cancer cells through down-regulation of AR and AR-related cofactors (AP-1, NF-kappaB and CBP)...
  77. ncbi request reprint A single-institution comparison between radical perineal and radical retropubic prostatectomy on perioperative and pathological outcomes for obese men: an analysis of the Duke Prostate Center database
    Nicholas J Fitzsimons
    Division of Urologic Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Urology 70:1146-51. 2007
    ....
  78. ncbi request reprint Prostate cancer laterality does not predict prostate-specific antigen recurrence after radical prostatectomy
    Vladimir Mouraviev
    Duke Prostate Center and Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 70:1141-5. 2007
    ..To evaluate biologic behaviors of unilateral cancers compared with bilateral cancers on prostate-specific antigen (PSA) recurrence after radical prostatectomy...
  79. ncbi request reprint Screening for prostate cancer in high risk populations
    William J Catalona
    Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    J Urol 168:1980-3; discussion 1983-4. 2002
    ..Consequently, screening at a younger age has been recommended for high risk men, however, there are limited data on actual screening results in young, high risk populations...
  80. ncbi request reprint Using the percentage of biopsy cores positive for cancer, pretreatment PSA, and highest biopsy Gleason sum to predict pathologic stage after radical prostatectomy: the Center for Prostate Disease Research nomograms
    Kevin J Gancarczyk
    Urology Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC, USA
    Urology 61:589-95. 2003
    ..To develop probability nomograms to predict pathologic outcome at the time of radical prostatectomy (RP) on the basis of established prognostic factors and prostate biopsy quantitative histology...
  81. ncbi request reprint Medical technologies for the diagnosis of prostate cancer
    Nicholas J Fitzsimons
    Division of Urologic Surgery and Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
    Expert Rev Med Devices 4:227-39. 2007
    ..Further improvement in prostate cancer detection hinges on the development of an imaging technique that is tumor specific and sensitive to biological aggressiveness...
  82. ncbi request reprint Update on outcomes research databases in prostate cancer 2006
    Stephen J Freedland
    Department of Surgery, Division of Urology, Duke University School of Medicine, Durham, NC 27710, USA
    Curr Opin Urol 16:168-72. 2006
    ....
  83. ncbi request reprint Open radical retropubic prostatectomy 2007: the true minimally invasive surgery for localized prostate cancer?
    Israel P Nosnik
    Duke University School of Medicine, Division of Urology, Box 3707, Durham, NC 27710, USA
    Expert Rev Anticancer Ther 7:1309-17. 2007
    ..The concepts we have articulated here are related to resection and avoidance of positive margins, limited intraoperative blood loss and pain control, which allow equivalence in these outcome areas, regardless of technique...
  84. ncbi request reprint Biochemical recurrence after definitive prostate cancer therapy. Part I: defining and localizing biochemical recurrence of prostate cancer
    John F Ward
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Curr Opin Urol 15:181-6. 2005
    ..It also evaluates the array of diagnostic tests frequently employed when biochemical recurrence has occurred...
  85. ncbi request reprint Obesity-related plasma hemodilution and PSA concentration among men with prostate cancer
    Lionel L Banez
    Division of Urologic Surgery and the Duke Prostate Center, and Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    JAMA 298:2275-80. 2007
    ..Because men with higher body mass index (BMI) have greater circulating plasma volumes, lower PSA concentrations among obese men may be due to hemodilution...
  86. ncbi request reprint Biochemical recurrence of prostate cancer
    Judd W Moul
    Department of Surgery, Uniformed Services University of the Health Services, Bethesda, Maryland, USA
    Curr Probl Cancer 27:243-72. 2003
  87. ncbi request reprint Radical perineal prostatectomy for the treatment of localized prostate cancer in morbidly obese patients
    Philipp Dahm
    Departments of Surgery Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina, USA
    J Urol 174:131-4. 2005
    ..We assessed the feasibility of radical perineal prostatectomy (RPP) in morbidly obese patients with clinically organ confined prostate cancer...
  88. doi request reprint Transdermal nicotine for analgesia after radical retropubic prostatectomy
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical System, Box 3094, Durham, North Carolina, USA
    Anesth Analg 107:999-1004. 2008
    ..We hypothesized that the preoperative application of a 7 mg nicotine patch would result in reduced postoperative analgesic requirements in patients undergoing radical retropubic prostatectomy (RRP) under general anesthesia...
  89. pmc Effects of family history and genetic polymorphism on the cost-effectiveness of chemoprevention with finasteride for prostate cancer
    Shelby D Reed
    Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina 27715, USA
    J Urol 185:841-7. 2011
    ..We estimated the cost-effectiveness of prostate cancer chemoprevention across risk groups defined by family history and number of risk alleles, and the cost-effectiveness of targeting chemoprevention to higher risk groups...
  90. doi request reprint Prostate cancer: an evolving paradigm
    Jorge R Caso
    Division of Urologic Surgery and Duke Prostate Center DPC, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Endourol 24:805-9. 2010
    ..The advent of focal therapy is bolstered by findings of increased unilateral disease with decreased tumor volume. Increasingly, targeted or delayed therapies may be possible within the current era of lower risk disease...
  91. ncbi request reprint Prostate cancer in the Baby Boomer generation: results from CaPSURE
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 70:1162-7. 2007
    ..We sought to characterize prostate cancer (CaP) presentation among this group, and determine whether treatment patterns differ between Baby Boomers and the preceding generation...
  92. ncbi request reprint Prostate-specific antigen versus prostate-specific antigen density as predictor of tumor volume, margin status, pathologic stage, and biochemical recurrence of prostate cancer
    Stephen A Brassell
    Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Urology 66:1229-33. 2005
    ..We also compared all PSAD derivatives to determine consistency...
  93. ncbi request reprint Low-risk prostate cancer patient: active treatment
    Judd W Moul
    Division of Urological Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Can J Urol 12:25-7. 2005
    ....
  94. ncbi request reprint Limited value of bone scintigraphy and computed tomography in assessing biochemical failure after radical prostatectomy
    Christopher J Kane
    Department of Urology, Naval Medical Center San Diego, San Diego, California, USA
    Urology 61:607-11. 2003
    ..To define the utility of bone scan and computed tomography (CT) in the evaluation of patients with biochemical recurrence after radical prostatectomy...
  95. ncbi request reprint Rising prostate-specific antigen after primary prostate cancer therapy
    John F Ward
    Nevada Cancer Institute, Las Vegas, Nevada, USA
    Nat Clin Pract Urol 2:174-82. 2005
    ..Data from animal models provide a rationale for the use of these therapies, but there is a lack of evidence to support prolongation of progression-free survival or cancer-specific survival...
  96. ncbi request reprint Surrogate end point for prostate cancer-specific mortality after radical prostatectomy or radiation therapy
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Natl Cancer Inst 95:1376-83. 2003
    ..Therefore, we evaluated the hypothesis that a short post-treatment PSA doubling time (PSA-DT) after radiation therapy is a surrogate end point for prostate cancer-specific mortality by analyzing two multi-institutional databases...
  97. ncbi request reprint Effect of age on biochemical disease-free outcome in patients with T1-T3 prostate cancer treated with definitive radiotherapy in an equal-access health care system: a radiation oncology report of the Department of Defense Center for Prostate Disease Resea
    Peter A S Johnstone
    Investigation Department, Naval Medical Center, San Diego, CA 92134, USA
    Int J Radiat Oncol Biol Phys 55:964-9. 2003
    ..The records of the Department of Defense Center for Prostate Disease Research were queried for the biochemical disease-free results of patients after definitive RT and analyzed by age...
  98. ncbi request reprint PSA progression following radical prostatectomy and radiation therapy: new standards in the new Millennium
    Bob Djavan
    Department of Urology, University of Vienna, Waehringer Guertel 18 20, Vienna A 1090, Austria
    Eur Urol 43:12-27. 2003
    ..At last, the use of artificial neural networks will certainly enhance the selection of patients submitted to radical treatments as well as the selection of relapsing patients to allow a more appropriate adjuvant therapy...
  99. ncbi request reprint The role of radical prostatectomy in patients with pretreatment prostate-specific antigen > or = 40 ng/mL
    Bill P Vanasupa
    Center for Prostate Disease Research, 1530 East Jefferson Street, Rockville, Maryland 20852, USA
    Urol Oncol 7:167-72. 2002
    ....
  100. ncbi request reprint Limitations of tissue microarrays in the evaluation of focal alterations of bcl-2 and p53 in whole mount derived prostate tissues
    Axel S Merseburger
    Department of Genitourinary Pathology, Armed Forces Institute of Pathology AFIP, Washington, DC 20306 6000, USA
    Oncol Rep 10:223-8. 2003
    ..The TMA technique is probably more informative and reliable in evaluating the prognostic value of homogeneously expressed biomarkers...
  101. ncbi request reprint Improved prostate cancer-specific survival and other disease parameters: impact of prostate-specific antigen testing
    Edmond L Paquette
    Center for Prostate Disease Research, Rockville, Maryland 20852, USA
    Urology 60:756-9. 2002
    ..To determine how the implementation of prostate-specific antigen (PSA) testing has affected disease-specific survival and other characteristics of prostate cancer...