Research Topics
Genomes and GenesSpecies | P G MoormanSummaryAffiliation: Duke University Medical Center Country: USA Publications
Research Grants
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Publications
Consumption of dairy products and the risk of breast cancer: a review of the literaturePatricia G Moorman
Cancer Prevention, Detection, and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA
Am J Clin Nutr 80:5-14. 2004..Measurement error may have attenuated any modest association with dairy products. The available epidemiologic evidence does not support a strong association between the consumption of milk or other dairy products and breast cancer risk...
Association of aspirin use and hormone receptor status with breast cancer riskPatricia G Moorman
JAMA 292:1426; author reply 1427. 2004
Age and menopausal effects of hormonal birth control and hormone replacement therapy in relation to breast cancer riskSumitra Shantakumar
Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, NC, USA
Am J Epidemiol 165:1187-98. 2007..These results emphasize that timing of exogenous hormone use is important. Women who used these hormones before menopause had elevated risks, but the harmful effects began to decline with age after menopause...
Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancerJoellen M Schildkraut
Department of Community and Family Medicine, Duke University Medical Center, Box 2949, Durham, NC 27710, USA
Cancer Epidemiol Biomarkers Prev 16:473-80. 2007..Two trinucleotide repeat polymorphisms have been described in exon 1 of the androgen receptor (AR) gene that may affect its function. Previous studies of ovarian cancer and AR repeat polymorphisms have been inconsistent...
Effect of hysterectomy with ovarian preservation on ovarian functionPatricia G Moorman
Cancer Prevention, Detection, and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Duke University, Durham, North Carolina 27705, USA
Obstet Gynecol 118:1271-9. 2011..To prospectively estimate the risk for earlier ovarian failure among women undergoing hysterectomy with ovarian preservation, as compared with women of similar age without hysterectomy...
Statins and cancer risk: what do we know and where do we go from here?Patricia G Moorman
Cancer Prevention, Detection and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Epidemiology 18:194-6. 2007..Given the widespread use of statins, continued monitoring of their risks and benefits is warranted...
A prospective study of weight gain after premenopausal hysterectomyPatricia G Moorman
Department of Community and Family Medicine, Box 2949, Duke University Medical Center, 2424 Ervin Road, Suite 602, Durham, NC 27705, USA
J Womens Health (Larchmt) 18:699-708. 2009..The purpose of this analysis was to assess weight gain in premenopausal women in the first year after hysterectomy compared with a control group of women with intact uteri and ovaries...
Antidepressant medication use [corrected] and risk of ovarian cancerPatricia G Moorman
Cancer Prevention, Detection, and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Obstet Gynecol 105:725-30. 2005..The objective of this paper was to evaluate whether women with ovarian cancer were more likely to report past use of antidepressants than control women...
Ovarian cancer risk factors in African-American and white womenPatricia G Moorman
Duke University Medical Center, 2424 Erwin Road, Suite 602, Durham, NC 27705, USA
Am J Epidemiol 170:598-606. 2009..There is a clear need for further research on etiologic factors for ovarian cancer in African-American women...
Cyclooxygenase 2 polymorphism (Val511Ala), nonsteroidal anti-inflammatory drug use and breast cancer in African American womenPatricia G Moorman
Cancer Prevention, Detection and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Suite 602, Box 2949, 2424 Erwin Road, Durham, NC 27710, USA
Cancer Epidemiol Biomarkers Prev 14:3013-4. 2005
Recreational physical activity and ovarian cancer risk and survivalPatricia G Moorman
Cancer Prevention, Detection and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27705, USA
Ann Epidemiol 21:178-87. 2011..We examined associations between self-reported physical activity and ovarian cancer risk and survival in a population-based, case-control study in North Carolina...
Racial differences in enrolment in a cancer genetics registryPatricia G Moorman
Cancer Prevention Detection and Control Research Program, Duke University Medical Center, 239 Hanes House, Trent Drive, Box 2949, Durham, NC 27710, USA
Cancer Epidemiol Biomarkers Prev 13:1349-54. 2004..Most studies have little information about nonparticipants, making it difficult to identify characteristics associated with enrolment and how they might vary by race...
Reported symptoms before and one year after hysterectomy in African American and white womenPatricia G Moorman
Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27705, USA
J Womens Health (Larchmt) 20:1035-42. 2011..This report compares reported symptoms in white and African American women before and 1-year after having a hysterectomy with at least one ovary retained...
Association between non-steroidal anti-inflammatory drugs (NSAIDs) and invasive breast cancer and carcinoma in situ of the breastPatricia G Moorman
Cancer Prevention, Detection, and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Cancer Causes Control 14:915-22. 2003..This study's objective was to examine the relationship between use of non-prescription and prescription NSAIDs and breast cancer and carcinoma in situ of the breast...
Antidepressant medications and their association with invasive breast cancer and carcinoma in situ of the breastPatricia G Moorman
Cancer Prevention, Detection, and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Epidemiology 14:307-14. 2003..Experimental studies in animals have suggested that antidepressants may promote the growth of mammary tumors, but epidemiologic data have not shown consistent associations between antidepressant use and breast cancer...
Ovulation and ovarian cancer: a comparison of two methods for calculating lifetime ovulatory cycles (United States)Patricia G Moorman
Cancer Prevention, Detection, and Control Research Program, Department of Community and Family Medicine, Duike Universiti Medical Center, Durham, NC 27710, USA
Cancer Causes Control 13:807-11. 2002..To compare two methods for calculating lifetime ovulatory cycles (LOC) to determine if more detailed menstrual cycle information results in stronger associations with ovarian cancer...
Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysisPatricia G Moorman
Cancer Prevention Detection and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27705, USA
Breast Cancer Res Treat 124:441-51. 2010..However, our results should be interpreted cautiously given the overall inconsistency in the epidemiologic literature on modifiers of BRCA1 and BRCA2...
Hormonal risk factors for ovarian cancer in premenopausal and postmenopausal womenPatricia G Moorman
Department of Community and Family Medicine, Cancer Prevention, Detection and Control Research Program, Duke University Medical Center, Durham, NC 27705, USA
Am J Epidemiol 167:1059-69. 2008..Findings suggest that associations between ovarian cancer and reproductive characteristics vary by menopausal status. Additional research is needed to further elucidate risk factors for postmenopausal disease...
Vitamin supplement use and breast cancer in a North Carolina populationP G Moorman
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
Public Health Nutr 4:821-7. 2001..We examined the association between self-reported vitamin supplement use and breast cancer among black women and white women...
Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinomaP G Moorman
Cancer Prevention, Detection and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Cancer 91:2258-62. 2001..Because these findings were based on a relatively small cohort of patients, corroborative studies with larger patient populations were needed...
Race, anthropometric factors, and stage at diagnosis of breast cancerP G Moorman
Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT, USA
Am J Epidemiol 153:284-91. 2001..These observations suggest that obesity and body fat distribution, in addition to socioeconomic and medical care factors, contribute to racial differences in stage at breast cancer diagnosis...
Menopausal hormones and risk of ovarian cancerPatricia G Moorman
Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am J Obstet Gynecol 193:76-82. 2005..The objective of this study was to determine if use of menopausal hormones was associated with ovarian cancer and if risk varied by type of hormone used...
Menopausal hormones and breast cancer in a biracial populationP G Moorman
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn, USA
Am J Public Health 90:966-71. 2000..This study examined the association between menopausal hormones and breast cancer in a biracial population...
No relationship between ovarian cancer risk and progesterone receptor gene polymorphism in a population-based, case-control study in North CarolinaJohnathan M Lancaster
Department of Obstetrics and Gynecology/Division of Gynecologic Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
Cancer Epidemiol Biomarkers Prev 12:226-7. 2003
Oral contraceptives and breast cancer among African-american women and white womenP G Moorman
Cancer Prevention, Detection, and Control Research Unit, Duke University Medical Center, Durham, North Carolina 27710, USA
J Natl Med Assoc 93:329-34. 2001..The similarity of the associations between African-American and white women suggest that racial differences in breast cancer incidence are not likely to be attributable to OC use...
Association between glioma and history of allergies, asthma, and eczema: a case-control study with three groups of controlsDora Il'yasova
Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Cancer Epidemiol Biomarkers Prev 18:1232-8. 2009..These controls seem to present a reasonable choice for clinic-centered case-control studies...
Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancerJoellen M Schildkraut
Comprehensive Cancer Center, Department of Community and Family Medicine, Duke University Medical Center, and Department of Statistical Science, Duke University, Durham, North Carolina, USA
Cancer Res 69:2349-57. 2009..This large study provides statistical evidence for a small increase in risk of ovarian cancer associated with common variants in the TP53 region...
Cyclin E overexpression in epithelial ovarian cancer characterizes an etiologic subgroupJoellen M Schildkraut
Department of Community and Family Medicine, Duke University Medical Center, Box 2949, Durham, NC 27710, USA
Cancer Epidemiol Biomarkers Prev 17:585-93. 2008..The objective of this study was to determine whether cyclin E overexpression defines an etiologically distinct subgroup of ovarian cancer...
Association between DNA damage response and repair genes and risk of invasive serous ovarian cancerJoellen M Schildkraut
Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
PLoS ONE 5:e10061. 2010....
IGF1 (CA)19 repeat and IGFBP3 -202 A/C genotypes and the risk of prostate cancer in Black and White menJoellen M Schildkraut
Program of Cancer Prevention, Detection and Control Research, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA
Cancer Epidemiol Biomarkers Prev 14:403-8. 2005..Further research is needed to confirm these findings...
Impact of progestin and estrogen potency in oral contraceptives on ovarian cancer riskJoellen M Schildkraut
Department of Community and Family Medicine, Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, NC 27710, USA
J Natl Cancer Inst 94:32-8. 2002..In this study, we investigate the relationship between the progestin and estrogen potency in combination OCs and the risk of developing ovarian cancer...
Analgesic drug use and risk of ovarian cancerJoellen M Schildkraut
Duke Comprehensive Cancer Center, Cancer Prevention, Detection and Control Research Program, Duke University Medical Center, Durham, North Carolina 27710, USA
Epidemiology 17:104-7. 2006..Previous epidemiologic research suggests that analgesic use may reduce the risk of ovarian cancer, although results are not consistent...
Pain predicts non-adherence to pap smear screening among middle-aged African American womenCathrine Hoyo
Department of Community and Family Medicine, Duke University Medical Center, Box 2914, Durham, NC 27710, USA
Prev Med 41:439-45. 2005..Middle-aged African American women have the highest incidence and mortality of invasive cervical cancer in the United States and the lowest adherence to pap smear screening...
Primary peritoneal and ovarian cancers: an epidemiological comparative analysisDelores J Grant
Department of Biology, North Carolina Central University, JLC Biomedical Biotechnology Research Institute, Durham, NC, USA
Cancer Causes Control 21:991-8. 2010..A larger study to determine risk factors for invasive serous PPC is warranted...
Comparative analysis of breast cancer risk factors among African-American women and White womenIngrid J Hall
Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Epidemiol 161:40-51. 2005..Hence, racial variations in both prevalences of and risks associated with particular factors may contribute to the higher incidence of breast cancer among younger African-American women...
COX-2 polymorphism, use of nonsteroidal anti-inflammatory drugs, and risk of colon cancer in African Americans (United States)Leah B Sansbury
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 8325, USA
Cancer Causes Control 17:257-66. 2006..We explored the association between the COX-2 Val511Ala SNP and risk of colon cancer among 240 African American cases and 326 African American controls in a population-based, case-control study in North Carolina...
Use of nonsteroidal antiinflammatory drugs and risk of colon cancer in a population-based, case-control study of African Americans and WhitesLeah B Sansbury
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 8325, USA
Am J Epidemiol 162:548-58. 2005..These results add new knowledge suggesting that the protective effect of NSAIDs against colon cancer is similar among African Americans and Whites...
Oral contraceptives and survival in breast cancer patients aged 20 to 54 yearsKatrina F Trivers
Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS K 52, Atlanta, GA 30341, USA
Cancer Epidemiol Biomarkers Prev 16:1822-7. 2007....
Epidemiology of basal-like breast cancerRobert C Millikan
Department of Epidemiology, CB 7435, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Breast Cancer Res Treat 109:123-39. 2008..Among younger African-American women, we estimate that up to 68% of basal-like breast cancer could be prevented by promoting breastfeeding and reducing abdominal adiposity...
Reproductive factors and breast cancer risk among older womenSumitra Shantakumar
Department of Epidemiology, CB 7435 McGavran Greenberg Hall, University of North Carolina School of Public Health, Chapel Hill, NC 27599 7435, USA
Breast Cancer Res Treat 102:365-74. 2007..Moreover, breastfeeding, one of the few potentially modifiable risk factors for breast cancer, was an important factor in decreasing risk among older parous postmenopausal women...
Consortium analysis of 7 candidate SNPs for ovarian cancerSusan J Ramus
Translational Research Laboratory, University College London EGA Institute for Women s Health, London, United Kingdom
Int J Cancer 123:380-8. 2008..These null results for SNPs identified from relatively large initial studies shows the importance of replicating associations by a consortium approach...
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer StudyLisa A Carey
Division of Hematology Oncology, School of Public Health, Department of Epidemiology, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC 27599 7305, USA
JAMA 295:2492-502. 2006..Gene expression analysis has identified several breast cancer subtypes, including basal-like, human epidermal growth factor receptor-2 positive/estrogen receptor negative (HER2+/ER-), luminal A, and luminal B...
Association between reproductive factors and breast cancer survival in younger womenKatrina F Trivers
Department of Epidemiology, University of North Carolina at Chapel Hill, CB 7435, Chapel Hill, NC 27599 7435, USA
Breast Cancer Res Treat 103:93-102. 2007..These results may help elucidate breast cancer progression mechanisms and enable a better understanding of how reproductive characteristics influence breast cancer survival...
Research Grants
- Ovarian Failure Among Hysterectomized WomenPatricia Moorman; Fiscal Year: 2007..It should have considerable public health impact given the high frequency of the procedure and the important health consequences of early ovarian failure. ..
