Robert J Mentz

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi Sleep-disordered breathing in patients with heart failure
    Robert J Mentz
    Duke University Medical Center, Duke Clinical Research Institute, 2301 Erwin Road, Durham, NC 27710, USA Electronic address
    Heart Fail Clin 10:243-50. 2014
  2. doi Heart failure with preserved ejection fraction: comparison of patients with and without angina pectoris (from the Duke Databank for Cardiovascular Disease)
    Robert J Mentz
    Department of Medicine, Duke University Medical Center, Durham, North Carolina Division of Cardiology, Duke University Medical Center, Durham, North Carolina Electronic address
    J Am Coll Cardiol 63:251-8. 2014
  3. ncbi Funding opportunities for clinical investigators in the early stages of career development in cardiovascular research
    Robert J Mentz
    Duke Clinical Research Institute, Duke University Medical Center, Duke University School of Medicine, 2400 Pratt Street, Durham, NC, 27705, USA
    J Thromb Thrombolysis 36:527-32. 2013
  4. doi Learning from recent trials and shaping the future of acute heart failure trials
    Robert J Mentz
    Duke University, Durham, NC Electronic address
    Am Heart J 166:629-35. 2013
  5. doi Race, exercise training, and outcomes in chronic heart failure: findings from Heart Failure - a Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION)
    Robert J Mentz
    Duke University, Durham, NC Electronic address
    Am Heart J 166:488-95. 2013
  6. doi The past, present and future of renin-angiotensin aldosterone system inhibition
    Robert J Mentz
    Duke University Medical Center, Durham, NC 27710, USA
    Int J Cardiol 167:1677-87. 2013
  7. ncbi Noncardiac comorbidities and acute heart failure patients
    Robert J Mentz
    Division of Cardiology, Department of Medicine, Duke University Medical Center, 2301 Erwin Road, Durham, NC 27710, USA
    Heart Fail Clin 9:359-67, vii. 2013
  8. doi Association of beta-blocker use and selectivity with outcomes in patients with heart failure and chronic obstructive pulmonary disease (from OPTIMIZE-HF)
    Robert J Mentz
    Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 111:582-7. 2013
  9. pmc Clinical characteristics, response to exercise training, and outcomes in patients with heart failure and chronic obstructive pulmonary disease: findings from Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION)
    Robert J Mentz
    Duke University Medical Center, Durham, NC, USA
    Am Heart J 165:193-9. 2013
  10. doi Comparison of Clinical characteristics and long-term outcomes of patients with ischemic cardiomyopathy with versus without angina pectoris (from the Duke Databank for Cardiovascular Disease)
    Robert J Mentz
    Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 109:1272-7. 2012

Detail Information

Publications31

  1. ncbi Sleep-disordered breathing in patients with heart failure
    Robert J Mentz
    Duke University Medical Center, Duke Clinical Research Institute, 2301 Erwin Road, Durham, NC 27710, USA Electronic address
    Heart Fail Clin 10:243-50. 2014
    ..Ongoing research into the roles of comorbidities such as SDB as a treatment target may lead to better clinical outcomes and improved quality of life for patients with heart failure. ..
  2. doi Heart failure with preserved ejection fraction: comparison of patients with and without angina pectoris (from the Duke Databank for Cardiovascular Disease)
    Robert J Mentz
    Department of Medicine, Duke University Medical Center, Durham, North Carolina Division of Cardiology, Duke University Medical Center, Durham, North Carolina Electronic address
    J Am Coll Cardiol 63:251-8. 2014
    ..This study investigated the characteristics and outcomes of patients with heart failure with preserved ejection fraction (HFpEF) and angina pectoris (AP)...
  3. ncbi Funding opportunities for clinical investigators in the early stages of career development in cardiovascular research
    Robert J Mentz
    Duke Clinical Research Institute, Duke University Medical Center, Duke University School of Medicine, 2400 Pratt Street, Durham, NC, 27705, USA
    J Thromb Thrombolysis 36:527-32. 2013
    ..This article highlights these opportunities in order to assist early career investigators in the development of a personalized research trajectory, which optimizes the potential for career success. ..
  4. doi Learning from recent trials and shaping the future of acute heart failure trials
    Robert J Mentz
    Duke University, Durham, NC Electronic address
    Am Heart J 166:629-35. 2013
    ..This review is based on discussions between scientists, clinical trialists, and regulatory representatives at the 9th Global Cardio Vascular Clinical Trialists Forum in Paris, France, from November 30 to December 1, 2012. ..
  5. doi Race, exercise training, and outcomes in chronic heart failure: findings from Heart Failure - a Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION)
    Robert J Mentz
    Duke University, Durham, NC Electronic address
    Am Heart J 166:488-95. 2013
    ..We aimed to investigate the association between race and outcomes and to explore interactions with exercise training in patients with ambulatory HF...
  6. doi The past, present and future of renin-angiotensin aldosterone system inhibition
    Robert J Mentz
    Duke University Medical Center, Durham, NC 27710, USA
    Int J Cardiol 167:1677-87. 2013
    ..Finally, ongoing clinical trials, opportunities for future trials and issues related to the barriers and approvability of novel RAAS inhibitors are highlighted. ..
  7. ncbi Noncardiac comorbidities and acute heart failure patients
    Robert J Mentz
    Division of Cardiology, Department of Medicine, Duke University Medical Center, 2301 Erwin Road, Durham, NC 27710, USA
    Heart Fail Clin 9:359-67, vii. 2013
    ..In some circumstances, careful attention to the diagnosis and management of these conditions in patients with AHF may help to improve patient outcomes. ..
  8. doi Association of beta-blocker use and selectivity with outcomes in patients with heart failure and chronic obstructive pulmonary disease (from OPTIMIZE-HF)
    Robert J Mentz
    Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 111:582-7. 2013
    ..In conclusion, despite concerns regarding β blockers in patients with HF with COPD, there was no evidence that β-blocker selectivity was associated with differences in outcomes for patients with HF with COPD versus those without...
  9. pmc Clinical characteristics, response to exercise training, and outcomes in patients with heart failure and chronic obstructive pulmonary disease: findings from Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION)
    Robert J Mentz
    Duke University Medical Center, Durham, NC, USA
    Am Heart J 165:193-9. 2013
    ..The aim of this study was to investigate the clinical characteristics, exercise training response, β-blocker selectivity, and outcomes in patients with heart failure (HF) and chronic obstructive pulmonary disease (COPD)...
  10. doi Comparison of Clinical characteristics and long-term outcomes of patients with ischemic cardiomyopathy with versus without angina pectoris (from the Duke Databank for Cardiovascular Disease)
    Robert J Mentz
    Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 109:1272-7. 2012
    ..03) (5-year event rates 85% vs 87% and 77% vs 73%, respectively). In conclusion, AP is common in patients with iCM despite medical therapy and previous revascularization and is associated with increased CV death or CV rehospitalization...
  11. doi Bronchodilators in heart failure patients with COPD: is it time for a clinical trial?
    Robert J Mentz
    Division of Cardiology, Department of Medicine, Duke Clinical Research Institute and Duke University Medical Center, Durham, North Carolina 27710, USA
    J Card Fail 18:413-22. 2012
    ....
  12. doi Implications of geographical variation on clinical outcomes of cardiovascular trials
    Robert J Mentz
    Duke University Medical Center, Durham, NC, USA
    Am Heart J 164:303-12. 2012
    ..This review is based on discussions between basic scientists and clinical trialists at the 8th Global Cardio Vascular Clinical Trialists Forum 2011 in Paris, France, from December 2 to 3...
  13. doi Clinical characteristics and outcomes of hospitalized heart failure patients with systolic dysfunction and chronic obstructive pulmonary disease: findings from OPTIMIZE-HF
    Robert J Mentz
    Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA
    Eur J Heart Fail 14:395-403. 2012
    ..We aimed to evaluate the clinical characteristics and outcomes of HF patients with systolic dysfunction and COPD in a large acute HF registry...
  14. doi Cardiorenal syndrome clinical trial end points
    Robert J Mentz
    Division of Cardiology, Department of Medicine, Duke University Medical Center, 2301 Erwin Road, Durham, NC 27705, USA
    Heart Fail Clin 7:519-28. 2011
    ..This article reviews the end points evaluated in key clinical trials of cardiorenal syndrome and synthesizes recent discussions about the appropriateness of end points for future trials...
  15. doi Clinical profile and prognostic value of low systolic blood pressure in patients hospitalized for heart failure with reduced ejection fraction: insights from the Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST) t
    Andrew P Ambrosy
    Department of Medicine, Stanford University School of Medicine, CA, USA
    Am Heart J 165:216-25. 2013
    ..The prognostic value of SBP after initiating inhospital therapy and the mode of death and etiology of cardiovascular readmissions based on SBP have not been well characterized in HHF...
  16. doi Association between diabetes mellitus and post-discharge outcomes in patients hospitalized with heart failure: findings from the EVEREST trial
    Satyam Sarma
    Division of Cardiology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Eur J Heart Fail 15:194-202. 2013
    ..DM is prevalent in patients hospitalized with HF, yet inconclusive data exist on the post-discharge outcomes of this patient population...
  17. doi Influence of documented history of coronary artery disease on outcomes in patients admitted for worsening heart failure with reduced ejection fraction in the EVEREST trial
    Robert J Mentz
    Duke University Medical Center, Durham, NC, USA
    Eur J Heart Fail 15:61-8. 2013
    ..We describe the clinical characteristics and mode-specific outcomes of HF patients with reduced ejection fraction (EF) and documented CAD in a large randomized trial...
  18. doi The impact of chronic obstructive pulmonary disease in patients hospitalized for worsening heart failure with reduced ejection fraction: an analysis of the EVEREST Trial
    Robert J Mentz
    Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC, USA
    J Card Fail 18:515-23. 2012
    ..We aimed to describe the characteristics and outcomes of patients with systolic dysfunction and COPD in a contemporary HF randomized trial...
  19. doi Atrial fibrillation or flutter on initial electrocardiogram is associated with worse outcomes in patients admitted for worsening heart failure with reduced ejection fraction: findings from the EVEREST Trial
    Robert J Mentz
    Duke University Medical Center, Durham, NC, USA
    Am Heart J 164:884-92.e2. 2012
    ..However, the clinical profile and outcomes of patients following hospitalization for HF with AF/AFL on initial electrocardiogram (ECG) has not been well studied...
  20. ncbi International differences in clinical characteristics, management, and outcomes in acute heart failure patients: better short-term outcomes in patients enrolled in Eastern Europe and Russia in the PROTECT trial
    Robert J Mentz
    Duke University, Durham, NC, USA
    Eur J Heart Fail 16:614-24. 2014
    ..We investigated regional differences in an international acute HF trial...
  21. doi Heart failure in elderly patients: distinctive features and unresolved issues
    Valentina Lazzarini
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Eur J Heart Fail 15:717-23. 2013
    ..The clinical characteristics, treatment patterns, and outcomes of elderly HF patients are explored. Finally, the main gaps regarding HF therapies in the elderly and the opportunities for future trials are highlighted. ..
  22. pmc Predictors of early dyspnoea relief in acute heart failure and the association with 30-day outcomes: findings from ASCEND-HF
    Robert J Mentz
    Duke University Medical Center, Durham, NC, USA
    Eur J Heart Fail 15:456-64. 2013
    ..To examine the characteristics associated with early dyspnoea relief during acute heart failure (HF) hospitalization, and its association with 30-day outcomes...
  23. doi Predictive value of low relative lymphocyte count in patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial
    Muthiah Vaduganathan
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Circ Heart Fail 5:750-8. 2012
    ..Limited data exist regarding whether relative lymphocyte count correlates with postdischarge outcomes in patients hospitalized for HF...
  24. doi The PROTECT in-hospital risk model: 7-day outcome in patients hospitalized with acute heart failure and renal dysfunction
    CHRISTOPHER M O'CONNOR
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    Eur J Heart Fail 14:605-12. 2012
    ..We aimed to identify the predictors of 7-day heart failure events or death in patients hospitalized with AHF...
  25. ncbi Decongestion in acute heart failure
    Robert J Mentz
    Duke University Medical Center, Durham, NC, USA
    Eur J Heart Fail 16:471-82. 2014
    ..This review is based on discussions among scientists, clinical trialists, and regulatory representatives at the 9th Global Cardio Vascular Clinical Trialists Forum in Paris, France, from 30 November to 1 December 2012. ..
  26. ncbi A crisis of the heart: an acute reversible cardiomyopathy bridged to recovery in a patient with Addison's disease
    Arun Krishnamoorthy
    From the Division of Cardiology and Division of Endocrinology, Duke University Medical Center, Durham, North Carolina Novant Health and Heart Vascular Institute, Charlotte, North Carolina and Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, North Carolina
    ASAIO J 59:668-70. 2013
    ..The patient was successfully treated with corticosteroid replacement and bridged with temporary mechanical circulatory support to eventual complete the recovery of native myocardial function. ..
  27. doi Covariate adjustment in heart failure randomized controlled clinical trials: a case analysis of the HF-ACTION trial
    CHRISTOPHER M O'CONNOR
    Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA
    Heart Fail Clin 7:497-500. 2011
    ..This article reviews the HF-ACTION trial to better understand whether covariate adjustment should be prespecified as the primary end point in HF clinical trials...
  28. doi Dysphagia in the setting of left ventricular assist device hemolysis
    Robert J Mentz
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    ASAIO J 59:322-3. 2013
    ....
  29. doi Patient selection for advanced heart failure therapy referral
    Alexander C Fanaroff
    From the Department of Medicine, Duke University Medical Center, Durham, NC Division of Cardiology, Duke University Medical Center, Durham, NC and Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, NC
    Crit Pathw Cardiol 13:1-5. 2014
    ..Decision making on referral to the heart transplant center is also summarized. ..
  30. ncbi Natriuretic Peptide-guided therapy for heart failure
    Robert J Mentz
    Department of Cardiology, Duke Clinical Research Institute, Durham, NC, USA
    Circ J 75:2031-7. 2011
    ..This article reviews the rationale, accumulated data, and unanswered questions for BGT in chronic HF...
  31. doi Diuretics and ultrafiltration in acute decompensated heart failure
    G Michael Felker
    Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
    J Am Coll Cardiol 59:2145-53. 2012
    ..This review summarizes available data on the use of both diuretics and UF in ADHF patients and identifies challenges and unresolved questions for each approach...