Rajendra H Mehta

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Chronobiological patterns of acute aortic dissection
    Rajendra H Mehta
    Division of Cardiology, University of Michigan, Ann Arbor, USA
    Circulation 106:1110-5. 2002
  2. ncbi request reprint Clinical correlates of long-term mortality after percutaneous interventions of saphenous vein grafts
    Rajendra H Mehta
    Department of Internal Medicine, Division of Cardiology, Duke University Medical Center and the Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 152:801-6. 2006
  3. ncbi request reprint Association of metabolic syndrome and its individual components with outcomes among patients with high-risk non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 168:182-188.e1. 2014
  4. pmc Pre-operative homocysteine levels and morbidity and mortality following cardiac surgery
    Marco Ranucci
    Department of Cardiothoracic vascular Anesthesia and Intensive Care, IRCCS Policlinico S Donato, Milan, Italy
    Eur Heart J 30:995-1004. 2009
  5. doi request reprint Comparison of bleeding and in-hospital mortality in Asian-Americans versus Caucasian-Americans with ST-elevation myocardial infarction receiving reperfusion therapy
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 109:925-31. 2012
  6. doi request reprint Prognostic significance of postprocedural sustained ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention (from the HORIZONS-AMI Trial)
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 109:805-12. 2012
  7. ncbi request reprint Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 109:320-6. 2012
  8. ncbi request reprint The impact of anthropomorphic indices on clinical outcomes in patients with acute ST-elevation myocardial infarction
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA, and Greenlane Cardiovascular Service, Auckland City Hospital, New Zealand
    Eur Heart J 28:415-24. 2007
  9. ncbi request reprint Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Arch Intern Med 166:2027-34. 2006
  10. ncbi request reprint The impact of emergency department structure and care processes in delivering care for non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 152:648-60. 2006

Collaborators

Detail Information

Publications107 found, 100 shown here

  1. ncbi request reprint Chronobiological patterns of acute aortic dissection
    Rajendra H Mehta
    Division of Cardiology, University of Michigan, Ann Arbor, USA
    Circulation 106:1110-5. 2002
    ..However, the effects of the time of the day, the day of the week, or monthly/seasonal changes on acute aortic dissection (AAD) have not been well studied...
  2. ncbi request reprint Clinical correlates of long-term mortality after percutaneous interventions of saphenous vein grafts
    Rajendra H Mehta
    Department of Internal Medicine, Division of Cardiology, Duke University Medical Center and the Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 152:801-6. 2006
    ..Accordingly, the goal of present study was to evaluate clinical correlates of long-term mortality and to develop a simple bedside tool for risk stratification in patients undergoing SVG interventions...
  3. ncbi request reprint Association of metabolic syndrome and its individual components with outcomes among patients with high-risk non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC Electronic address
    Am Heart J 168:182-188.e1. 2014
    ....
  4. pmc Pre-operative homocysteine levels and morbidity and mortality following cardiac surgery
    Marco Ranucci
    Department of Cardiothoracic vascular Anesthesia and Intensive Care, IRCCS Policlinico S Donato, Milan, Italy
    Eur Heart J 30:995-1004. 2009
    ..Whether elevated homocysteine further increases the morbidity and mortality in patients undergoing cardiac surgery on cardiopulmonary bypass (CPB) (a prothrombotic state itself) remains less known...
  5. doi request reprint Comparison of bleeding and in-hospital mortality in Asian-Americans versus Caucasian-Americans with ST-elevation myocardial infarction receiving reperfusion therapy
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 109:925-31. 2012
    ....
  6. doi request reprint Prognostic significance of postprocedural sustained ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention (from the HORIZONS-AMI Trial)
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 109:805-12. 2012
    ..Further studies are required to address the prognostic significance of VT/VF in patients with STEMI undergoing PPCI...
  7. ncbi request reprint Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 109:320-6. 2012
    ..These data highlight the importance of understanding factors associated with gender-related differences in bleeding and represent an opportunity for improving outcomes of women and men with fibrinolytic-treated STEMI...
  8. ncbi request reprint The impact of anthropomorphic indices on clinical outcomes in patients with acute ST-elevation myocardial infarction
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA, and Greenlane Cardiovascular Service, Auckland City Hospital, New Zealand
    Eur Heart J 28:415-24. 2007
    ..However, the relative prognostic importance of these measures over other baseline variables is less known...
  9. ncbi request reprint Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Arch Intern Med 166:2027-34. 2006
    ..We sought to determine recent trends in adherence to guideline-based therapies for NSTE ACS...
  10. ncbi request reprint The impact of emergency department structure and care processes in delivering care for non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 152:648-60. 2006
    ..We sought to assess the influence of emergency department (ED) structure and care processes on adherence to practice guidelines for the treatment of patients with non-ST-segment elevation acute coronary syndromes...
  11. ncbi request reprint Challenges in predicting the need for coronary artery bypass grafting at presentation in patients with non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 98:624-7. 2006
    ....
  12. doi request reprint Clinical significance of post-procedural TIMI flow in patients with cardiogenic shock undergoing primary percutaneous coronary intervention
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
    JACC Cardiovasc Interv 2:56-64. 2009
    ....
  13. ncbi request reprint Impact of internal mammary artery conduit on long-term outcomes after percutaneous intervention of saphenous vein graft
    Rajendra H Mehta
    Division of Cardiology, Department of Internal Medicine, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC, USA
    Circulation 114:I396-401. 2006
    ..The influence of an internal mammary artery (IMA) graft on long-term outcomes after percutaneous saphenous vein graft (SVG) intervention is currently unknown...
  14. ncbi request reprint Prediction of one-year mortality among 30-day survivors after primary percutaneous coronary interventions
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 97:817-22. 2006
    ....
  15. ncbi request reprint Differences in the clinical features and outcomes in African Americans and whites with myocardial infarction
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC, USA
    Am J Med 119:70.e1-8. 2006
    ..Accordingly, the current study examines the relationship of African American race to patient-related clinical factors, angiographic findings, and clinical events...
  16. ncbi request reprint Comparison of coronary stenting versus conventional balloon angioplasty on five-year mortality in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 96:901-6. 2005
    ..These data support the routine use of coronary stenting in most patients undergoing primary PCI, when feasible...
  17. ncbi request reprint The winter peak in the occurrence of acute aortic dissection is independent of climate
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC, USA
    Chronobiol Int 22:723-9. 2005
    ....
  18. ncbi request reprint Does circadian and seasonal variation in occurrence of acute aortic dissection influence in-hospital outcomes?
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Chronobiol Int 22:343-51. 2005
    ..While highest incidence of AAD occurred in the morning and winter, clinical events (including mortality) were similar during the four different periods of the 24 h (chi2 = 1.9, p = 0.60) and seasonal (chi2 = 1.2, p = 0.75) periods...
  19. ncbi request reprint Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgery
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 114:2208-16; quiz 2208. 2006
    ..Estimation of an individual patient's risk for postoperative dialysis can support informed clinical decision making and patient counseling...
  20. ncbi request reprint Characterizing young patients with diabetes and non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, P O Box 17969, Durham, NC 27715, USA
    Diabetes Care 30:731-3. 2007
  21. doi request reprint Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention
    Rajendra H Mehta
    Duke Clinical Research Institute, Box 17969, Durham, NC 27715, USA
    JAMA 301:1779-89. 2009
    ....
  22. ncbi request reprint Clinical characteristics associated with poor long-term survival among patients with diabetes mellitus undergoing saphenous vein graft interventions
    Rajendra H Mehta
    Duke University Medical Center, Durham, NC, USA
    Am Heart J 156:728-35. 2008
    ..Limited data exist on the long-term outcomes among diabetic patients undergoing saphenous vein graft (SVG) interventions. Thus, the baseline clinical factors associated with long-term adverse events in these patients are less known...
  23. doi request reprint Variation in the use of stress testing and outcomes in patients with non-ST-elevation acute coronary syndromes: insights from GUSTO IIb
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Box 17969, Durham, NC 27715, USA
    Eur Heart J 29:880-7. 2008
    ....
  24. doi request reprint Clinical characteristics and in-hospital outcomes of patients with cardiogenic shock undergoing coronary artery bypass surgery: insights from the Society of Thoracic Surgeons National Cardiac Database
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 117:876-85. 2008
    ..There exist few studies that characterize contemporary clinical features and outcomes or risk factors for operative mortality in cardiogenic shock (CS) patients undergoing coronary artery bypass grafting (CABG)...
  25. doi request reprint Body mass index and effectiveness of reperfusion strategies: implications for the management of patients with ST-elevation myocardial infarction
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Interv Cardiol 21:8-14. 2008
    ..Whether the relatively lower dose results in lower effectiveness of fibrinolytic agents versus primary percutaneous coronary interventions (PCI) in patients with higher body mass index (BMI) is not known...
  26. ncbi request reprint Clinical and angiographic correlates of short- and long-term mortality in patients undergoing coronary artery bypass grafting
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 100:1538-42. 2007
    ..These differences should be kept in context when counseling patients undergoing CABG and may help facilitate targeted strategies to improve short- and long-term mortality risks after CABG...
  27. ncbi request reprint Association of patient case-mix adjustment, hospital process performance rankings, and eligibility for financial incentives
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, Durham, North Carolina 27715, USA
    JAMA 300:1897-903. 2008
    ..While most comparisons of hospital outcomes adjust for patient characteristics, process performance comparisons typically do not...
  28. pmc Modifiable risk factors control and its relationship with 1 year outcomes after coronary artery bypass surgery: insights from the REACH registry
    Rajendra H Mehta
    Duke Clinical Research Institute, 2400 Pratt Street, PO Box 17969, Durham, NC, USA
    Eur Heart J 29:3052-60. 2008
    ..To evaluate the influence of achieving secondary prevention target treatment goals for cardiovascular (CV) risk factors on clinical outcomes in patients with prior coronary artery bypass surgery (CABG)...
  29. ncbi request reprint The relation between clinical features, angiographic findings, and the target lesion revascularization rate in patients receiving the endeavor zotarolimus-eluting stent for treatment of native coronary artery disease: an analysis of ENDEAVOR I, ENDEAVOR I
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 100:62M-70M. 2007
    ..These data provide insight into the clinical and angiographic factors that predict TLR at 9 months in ZES-treated patients, making possible the focused surveillance of selected ZES-treated patients who might be at greater risk of TLR...
  30. ncbi request reprint Timing of death and myocardial infarction in patients with non-ST elevation acute coronary syndromes: insights from randomized clinical trials
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    J Interv Cardiol 20:299-306. 2007
    ..Adverse events occur following non-ST elevation acute coronary syndromes (NSTE ACS). However, the timing of these events in relation to index event is less clear...
  31. doi request reprint Influence of preoperative renal dysfunction on one-year bypass graft patency and two-year outcomes in patients undergoing coronary artery bypass surgery
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, Durham, NC 27715, USA
    J Thorac Cardiovasc Surg 136:1149-55. 2008
    ..Limited information exists on the impact of preoperative renal dysfunction on internal thoracic artery and saphenous vein graft failure and 2-year clinical outcomes in patients undergoing coronary artery bypass surgery...
  32. ncbi request reprint Comparison of in-hospital outcomes of patients with versus without previous carotid endarterectomy undergoing carotid stenting (from the German ALKK CAS Registry)
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 99:1288-93. 2007
    ..This low risk along with the less invasive nature of the procedure should make CAS an attractive and perhaps preferred option for the treatment of these patients...
  33. doi request reprint Association of weight change with subsequent outcomes in patients hospitalized with acute decompensated heart failure
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 103:76-81. 2009
    ..e., death and/or rehospitalization) in patients with HF in the design of treatment strategies for novel therapeutic agents in randomized controlled clinical trials...
  34. ncbi request reprint Impact of initial heart rate and systolic blood pressure on relation of age and mortality among fibrinolytic-treated patients with acute ST-elevation myocardial infarction presenting with cardiogenic shock
    Rajendra H Mehta
    Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 99:793-6. 2007
    ..This information may help physicians in deciding treatment options for patients with cardiogenic shock and counseling them about their risks...
  35. ncbi request reprint Ischemia-driven target vessel revascularization after-primary percutaneous coronary intervention: patients at risk and their outcomes
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Interv Cardiol 18:149-54. 2005
    ..Importantly, our data suggest that no increase in mortality occur, if ITVR is promptly performed to treat recurrent ischemia after primary PCI...
  36. ncbi request reprint Acute clopidogrel use and outcomes in patients with non-ST-segment elevation acute coronary syndromes undergoing coronary artery bypass surgery
    Rajendra H Mehta
    Division of Cardiology and the Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 48:281-6. 2006
    ....
  37. doi request reprint Effectiveness and safety of carotid artery stenting for significant carotid stenosis in patients with contralateral occlusion (from the German ALKK-CAS Registry experience)
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 104:725-31. 2009
    ....
  38. doi request reprint Relationship of sustained ventricular tachyarrhythmias to outcomes in patients undergoing primary percutaneous coronary intervention with varying underlying baseline risk
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 161:782-9. 2011
    ....
  39. pmc Relationship of the time interval between cardiac catheterization and elective coronary artery bypass surgery with postprocedural acute kidney injury
    Rajendra H Mehta
    Duke Clinical Research Institute, Box 17969, Durham, NC 27715, USA
    Circulation 124:S149-55. 2011
    ..However, these studies, because of the small number of patients, were unable to adequately account for patient case-mix and included both those undergoing elective surgery and those undergoing urgent surgery...
  40. doi request reprint Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV trial
    Rajendra H Mehta
    Duke Clinical Research Institute, Box 17969, Durham, NC 27715, USA
    Circulation 124:280-8. 2011
    ....
  41. doi request reprint Association of mortality with years of education in patients with ST-segment elevation myocardial infarction treated with fibrinolysis
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 57:138-46. 2011
    ..The purpose of this study was to examine the association between lower socioeconomic status (SES), as ascertained by years of education, and outcomes in patients with acute ST-segment elevation myocardial infarction (STEMI)...
  42. doi request reprint Race, Bleeding, and Outcomes in STEMI Patients Treated with Fibrinolytic Therapy
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Am J Med 124:48-57. 2011
    ....
  43. doi request reprint Impact of recovery of renal function on long-term mortality after coronary artery bypass grafting
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 106:1728-34. 2010
    ..Thus, major emphasis should be on prevention of ARF in patients undergoing CABG...
  44. ncbi request reprint Influence of transfer-in rates on quality of care and outcomes at receiving hospitals in patients with non-ST-segment elevation myocardial infarction
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 160:405-11. 2010
    ....
  45. ncbi request reprint Percutaneous coronary intervention or coronary artery bypass surgery for cardiogenic shock and multivessel coronary artery disease?
    Rajendra H Mehta
    The Duke University Medical Center and Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 159:141-7. 2010
    ..Although both percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are used in patients with CS with multivessel coronary disease, the optimal revascularization strategy in this setting remains unknown...
  46. doi request reprint Reoperation for bleeding in patients undergoing coronary artery bypass surgery: incidence, risk factors, time trends, and outcomes
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Circ Cardiovasc Qual Outcomes 2:583-90. 2009
    ..Reoperation for bleeding represents an important complication in patients undergoing coronary artery bypass surgery (CABG). Yet, few studies have characterized risk factors and patient outcomes of this event...
  47. ncbi request reprint Association of height with outcomes in patients with acute myocardial infarction receiving reperfusion therapy
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 95:1371-5. 2005
    ..962 (95% CI 0.896 to 1.033). These data indicate that height-related differences in 30-day mortality are explained in large part by height-related differences in patients' clinical characteristics...
  48. doi request reprint Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI) trial
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 163:797-803. 2012
    ..Information on practice patterns and outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary interventions (PCIs) in Canada vs United States is limited...
  49. doi request reprint Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    N Engl J Med 361:235-44. 2009
    ....
  50. pmc Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, DUMC Box 3850, Durham, NC 27705, USA
    Circulation 125:749-56. 2012
    ..In this retrospective analysis, we examined the relationship between VGF, assessed by coronary angiography 12 to 18 months after coronary artery bypass graft surgery, and subsequent clinical outcomes...
  51. ncbi request reprint A rapid-cycle collaborative model to promote guidelines for acute myocardial infarction
    Cecelia K Montoye
    Division of Cardiology, University of Michigan UM, Ann Arbor, Michigan, USA
    Jt Comm J Qual Saf 29:468-78. 2003
    ..The GAP Pilot Project formed the basis for this project, which supported caregivers' efforts to improve their processes and consistently apply the evidence-based guidelines for AMI care...
  52. ncbi request reprint Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting
    Judson B Williams
    Duke Clinical Research Institute, Durham, NC, USA
    J Thromb Thrombolysis 36:384-93. 2013
    ..There may be better outcomes with clopidogrel among patients having off-pump surgery. Adequately powered randomized clinical trials are needed to determine the role of dual antiplatelet therapy after CABG...
  53. ncbi request reprint Influence of concurrent renal dysfunction on outcomes of patients with acute coronary syndromes and implications of the use of glycoprotein IIb/IIIa inhibitors
    Rosario V Freeman
    Division of Cardiology, University of Washington, Seattle, Washington 98195, USA
    J Am Coll Cardiol 41:718-24. 2003
    ..The purpose of this study was to examine the in-hospital outcome and influence of glycoprotein (GP) IIb/IIIa antagonists on patients with acute coronary syndromes (ACS) across a range of renal function...
  54. pmc Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction
    Jonathan P Piccini
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Crit Care Med 39:78-83. 2011
    ..The objective of this analysis was to describe the survival of patients with sustained ventricular tachycardia/ventricular fibrillation after myocardial infarction according to antiarrhythmic drug treatment...
  55. pmc Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results
    Renato D Lopes
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 164:379-386.e1. 2012
    ..We compared the 5-year clinical outcomes of patients in PREVENT IV treated with edifoligide and placebo to identify predictors of long-term clinical outcomes...
  56. ncbi request reprint Effects of age on the quality of care provided to older patients with acute myocardial infarction
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med 114:307-15. 2003
    ..Furthermore, it is unclear whether age-associated variations in care are similar or vary among treatments...
  57. doi request reprint N-terminal pro-brain natriuretic peptide and outcomes in patients undergoing surgical ventricular restoration
    Andrea Ballotta
    Department of Cardiothoracic Anesthesia and Intensive Care Unit, 20097 San Donato Milanese, Milan, Italy
    Am J Cardiol 105:640-4. 2010
    ..In conclusion, preoperative NT-pro-BNP determination may be of value in stratifying the risk for major morbidity after SVR...
  58. ncbi request reprint Prognostic significance of an elevated creatine kinase in the absence of an elevated troponin I during an acute coronary syndrome
    Kimberly C Yee
    Division of Cardiology, Department of Internal Medicine, University of Michigan Health Systems, Ann Arbor, Michigan, USA
    Am J Cardiol 92:1442-4. 2003
    ..This risk is accentuated in troponin-negative, CK-MB positive patients who do not demonstrate ST elevation by electrocardiogram...
  59. ncbi request reprint Differences in quality of care among patients hospitalized with atrial fibrillation as primary or secondary cause for admission
    Michael J Lim
    The Duke Clinical Research Institute, Durham, NC, USA
    Int J Qual Health Care 17:255-8. 2005
    ..Accordingly, we sought to evaluate the differences in quality of care of Medicare patients admitted with primary diagnosis versus secondary diagnosis of AF...
  60. ncbi request reprint The new definition of myocardial infarction: diagnostic and prognostic implications in patients with acute coronary syndromes
    Mark A Meier
    Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48105, USA
    Arch Intern Med 162:1585-9. 2002
    ..The clinical implications of the recently revised criteria for diagnosis of acute myocardial infarction (AMI) in patients with suspected acute coronary syndromes are unknown...
  61. ncbi request reprint Impact of combined pharmacologic treatment with clopidogrel and a statin on outcomes of patients with non-ST-segment elevation acute coronary syndromes: perspectives from a large multinational registry
    Michael J Lim
    Division of Cardiology, School of Medicine, Saint Louis University, St Louis, MO, USA
    Eur Heart J 26:1063-9. 2005
    ..To evaluate clinical outcomes associated with the combined use of clopidogrel and statins vs. clopidogrel alone on a background of aspirin therapy in patients with the spectrum of acute coronary syndromes (ACS)...
  62. ncbi request reprint Outcomes associated with the use of secondary prevention medications after coronary artery bypass graft surgery
    Abhinav Goyal
    Duke Clinical Research Institute and Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 83:993-1001. 2007
    ..We investigated whether greater use of secondary prevention medications after coronary artery bypass graft surgery is associated with improved clinical outcomes...
  63. ncbi request reprint Relationship of incorrect dosing of fibrinolytic therapy and clinical outcomes
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, Durham, NC 27710, USA
    JAMA 293:1746-50. 2005
    ..Incorrect dosing of alteplase has been associated with worse clinical outcomes in patients. However, patients at high risk of adverse events are more prone to dosing errors, thus confounding this relationship...
  64. ncbi request reprint Influence of inpatient service specialty on care processes and outcomes for patients with non ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Duke University Medical Center and Duke Clinical Research Institute, 2400 Pratt St, Durham, NC 27705, USA
    Circulation 116:1153-61. 2007
    ..Since the broad dissemination of practice guidelines, the association of specialty care with the treatment of patients with acute coronary syndromes has not been studied...
  65. ncbi request reprint Reperfusion strategies for acute myocardial infarction in the elderly: benefits and risks
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 45:471-8. 2005
    ..Clearly targeted large-scale clinical trials are needed to evaluate the relative merits of available reperfusion strategies as well as newer antithrombotic adjunctive therapies in the elderly with STEMI...
  66. ncbi request reprint Warfarin use and outcomes in patients with atrial fibrillation complicating acute coronary syndromes
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am J Med 123:134-40. 2010
    ....
  67. pmc Cardiac catheterization within 1 to 3 days of proximal aortic surgery is not associated with increased postoperative acute kidney injury
    Nicholas D Andersen
    Division of Thoracic and Cardiovascular Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Thorac Cardiovasc Surg 143:1404-10. 2012
    ..The relationship between catheterization timing and acute kidney injury after proximal aortic surgery remains unknown...
  68. ncbi request reprint Documented traditional cardiovascular risk factors and mortality in non-ST-segment elevation myocardial infarction
    Matthew T Roe
    Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 153:507-14. 2007
    ....
  69. ncbi request reprint Influence of age on outcomes in patients undergoing mitral valve replacement
    Rajendra H Mehta
    Division of Cardiology, University of Michigan, Ann Arbor 48105, USA
    Ann Thorac Surg 74:1459-67. 2002
    ....
  70. doi request reprint Age and outcomes in ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: findings from the APEX-AMI trial
    S Michael Gharacholou
    Division of Cardiology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Arch Intern Med 171:559-67. 2011
    ....
  71. doi request reprint Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial
    John H Alexander
    Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    JAMA 299:1777-87. 2008
    ..Phase 2 trial data suggest that MC-1 may reduce death or MI in high-risk patients undergoing CABG surgery...
  72. doi request reprint International variation in and factors associated with hospital readmission after myocardial infarction
    Robb D Kociol
    Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA
    JAMA 307:66-74. 2012
    ..Recently, 30-day readmission rates have been proposed as a metric for care of patients with STEMI. However, international rates and predictors of 30-day readmission after STEMI have not been studied...
  73. doi request reprint A randomized, double-blind, placebo-controlled, multicenter study to evaluate the cardioprotective effects of MC-1 in patients undergoing high-risk coronary artery bypass graft surgery: MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft
    Rajendra H Mehta
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 155:600-8. 2008
    ....
  74. doi request reprint Achieving rapid reperfusion with primary percutaneous coronary intervention remains a challenge: insights from American Heart Association's Get With the Guidelines program
    Rajendra H Mehta
    Duke Clinical Research Institute and Duke University Medical Center, Durham, NC, USA
    Am Heart J 155:1059-67. 2008
    ..Although preferably D2B times should be <or=90 minutes, it is unclear how consistently this is achieved in community practice, particularly in women, elderly people, and minorities...
  75. pmc Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness) risk model and discharge score
    CHRISTOPHER M O'CONNOR
    Duke Clinical Research Institute, Duke University Medical Center, 2400 North Pratt Street, Box 3356, Durham, North Carolina 27705, USA
    J Am Coll Cardiol 55:872-8. 2010
    ..Identifying high-risk heart failure (HF) patients at hospital discharge may allow more effective triage to management strategies...
  76. ncbi request reprint Acute ST-segment elevation myocardial infarction: critical care perspective
    Amrita M Karve
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Crit Care Clin 23:685-707, v. 2007
    ..Despite its high mortality, prognosis can be improved with timely and effective use of evidence-based treatment in the acute setting. This review outlines the critical care management strategies for ST-segment MI (STEMI)...
  77. ncbi request reprint Taking the national guideline for care of acute myocardial infarction to the bedside: developing the guideline applied in practice (GAP) initiative in Southeast Michigan
    Kim A Eagle
    Division of Cardiology, University of Michigan Health System, Ann Arbor, Michigan, USA
    Jt Comm J Qual Improv 28:5-19. 2002
    ..Ten Michigan hospitals participated in implementing the project, which began in March 2000...
  78. ncbi request reprint Performance measures have a major effect on cardiovascular outcomes: a review
    Rajendra H Mehta
    The Duke Clinical Research Institute, Durham, NC Duke University Medical Center, Durham, NC 27715, USA
    Am J Med 120:398-402. 2007
    ..Higher quality of care, as documented by better performance based on measures derived from practice guidelines, is associated with improved outcomes in patients with cardiovascular disease...
  79. ncbi request reprint Improving quality of care for acute myocardial infarction: The Guidelines Applied in Practice (GAP) Initiative
    Rajendra H Mehta
    Division of Cardiology, University of Michigan Hospital, 1500 E Medical Center Dr, Ann Arbor, MI 48109, USA
    JAMA 287:1269-76. 2002
    ..However, it is unknown if a structured initiative for improving care of patients with AMI can be effectively implemented at a wide variety of hospitals...
  80. doi request reprint Diagnosing acute myocardial infarction in patients with left bundle branch block
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 108:782-8. 2011
    ....
  81. ncbi request reprint Clinical quality in non-ST-elevation acute coronary syndromes
    Robert M Califf
    The Duke University Medical Center and Duke Clinical Research Institute, Durham, NC 27710, USA
    Am J Med 120:930-5. 2007
    ....
  82. doi request reprint Evaluation of a new heparin agent in percutaneous coronary intervention: results of the phase 2 evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) Trial
    Sunil V Rao
    Duke Clinical Research Institute, Durham, NC, USA
    Circulation 121:1713-21. 2010
    ..We performed a phase 2 randomized trial to evaluate the safety and feasibility of M118 in the setting of elective percutaneous coronary intervention...
  83. pmc Antidepressant use, depression, and survival in patients with heart failure
    CHRISTOPHER M O'CONNOR
    Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, 2400 N Pratt St, Box 3356, Durham, NC 27705, USA
    Arch Intern Med 168:2232-7. 2008
    ..Because depression has also been shown to be associated with increased mortality in these patients, it remains unclear if this association is attributable to the use of antidepressants or to depression...
  84. doi request reprint Influence of the timing of cardiac catheterization and the amount of contrast media on acute renal failure after cardiac surgery
    Marco Ranucci
    Department of Cardiothoracic vascular Anesthesia and Intensive Care, Policlinico S Donato, Milan, Italy
    Am J Cardiol 101:1112-8. 2008
    ....
  85. ncbi request reprint Association of statin therapy with outcomes of acute coronary syndromes: the GRACE study
    Frederick A Spencer
    Department of Medicine Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Ann Intern Med 140:857-66. 2004
    ..Statins administered early in patients with acute coronary syndromes may lead to modest reductions in recurrent ischemic events...
  86. ncbi request reprint Assessing performance reports to individual providers in the care of acute coronary syndromes
    Obli Mani
    Hahnemann University, Philadelphia, USA
    Jt Comm J Qual Improv 28:220-32. 2002
    ....
  87. ncbi request reprint Effectiveness of primary percutaneous coronary intervention compared with that of thrombolytic therapy in elderly patients with acute myocardial infarction
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Mich, USA
    Am Heart J 147:253-9. 2004
    ....
  88. ncbi request reprint Acute ischemic stroke in hospitalized medicare patients: evaluation and treatment
    Canopy Roychoudhury
    Michigan Peer Review Organization, Plymouth, Mich 48170, USA
    Stroke 35:e22-3. 2004
    ..This study describes several quality indicators of care in hospitalized stroke patients in Michigan from 1998 to 1999...
  89. ncbi request reprint Comparison of patients with acute coronary syndrome with and without systemic hypertension
    Silja K Majahalme
    Tampere University Hospital, Tampere, Finland
    Am J Cardiol 92:258-63. 2003
    ....
  90. ncbi request reprint Acute type A aortic dissection in the elderly: clinical characteristics, management, and outcomes in the current era
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Michigan 48105, USA
    J Am Coll Cardiol 40:685-92. 2002
    ..We sought to evaluate the clinical characteristics, management, and outcomes of elderly patients with acute type A aortic dissection...
  91. ncbi request reprint Patient outcomes after fibrinolytic therapy for acute myocardial infarction at hospitals with and without coronary revascularization capability
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Michigan 48109, USA
    J Am Coll Cardiol 40:1034-40; discussion 1041-3. 2002
    ..This study evaluated clinical outcomes in patients with acute myocardial infarction (MI) treated with fibrinolytic therapy in hospitals with and without coronary revascularization capability...
  92. ncbi request reprint Syncope in acute aortic dissection: diagnostic, prognostic, and clinical implications
    Brahmajee K Nallamothu
    University of Michigan Medical School, Ann Arbor, Michigan, USA
    Am J Med 113:468-71. 2002
    ..Syncope is a well-recognized symptom of acute aortic dissection, often indicating the development of dangerous complications such as cardiac tamponade...
  93. ncbi request reprint Clinical and angiographic correlates and outcomes of suboptimal coronary flow inpatients with acute myocardial infarction undergoing primary percutaneous coronary intervention
    Rajendra H Mehta
    University of Michigan, Ann Arbor, Michigan, USA
    J Am Coll Cardiol 42:1739-46. 2003
    ..The purpose of this study was to determine the clinical and angiographic correlates and outcomes of patients with suboptimal coronary flow after primary percutaneous coronary interventions (PCI)...
  94. pmc Valve surgery in octogenarians: in-hospital and long-term outcomes
    Eduardo Bossone
    Institute of Clinical Physiology, National Research Council of Italy, Lecce Section
    Can J Cardiol 23:223-7. 2007
    ..However, their preoperative risk factors, and in-hospital and long-term outcomes have not been thoroughly investigated...
  95. ncbi request reprint Frequency and outcomes of acute renal failure following thoracic aortic stent-graft placement
    Holger Eggebrecht
    The Department of Cardiology, West German Heart Center Essen, Essen, Germany
    Am J Cardiol 98:458-63. 2006
    ..In addition, identification of an at-risk subset may allow modification of reversible periprocedural factors that may help decrease postprocedural ARF...
  96. ncbi request reprint Relation of timing of cardiac catheterization to outcomes in patients with non-ST-segment elevation myocardial infarction or unstable angina pectoris enrolled in the multinational global registry of acute coronary events
    Gilles Montalescot
    Institut de Cardiologie, Centre Hospitalier Universitaire, Pitié Salptrière, Paris, France
    Am J Cardiol 95:1397-403. 2005
    ....
  97. ncbi request reprint Improved quality of stroke care for hospitalized Medicare beneficiaries in Michigan
    Bradley S Jacobs
    Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA
    Stroke 36:1227-31. 2005
    ..We investigated whether these and other measures improved after a quality improvement initiative...
  98. ncbi request reprint Branch vessel complications are increased in aortic dissection patients with renal insufficiency
    Joshua A Beckman
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA, USA
    Vasc Med 9:267-70. 2004
    ..Upon recognition, renal impairment indicates a need for close monitoring, aggressive blood pressure control, and evaluation of aortic branch vessel circulations...
  99. ncbi request reprint Influence of circadian rhythm on mortality after myocardial infarction: data from a prospective cohort of emergency calls
    Roberto Manfredini
    Section of Internal Medicine, Department of Clinical and Experimental Medicine, University of Ferrara, Via Savonarola 9, I 14400 Ferrara, Italy
    Am J Emerg Med 22:555-9. 2004
    ..This could be of practical interest for emergency doctors and could have significant implications for acute treatment, because several studies have reported a lowered efficacy of thrombolytic drugs in the morning hours...
  100. ncbi request reprint Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE)
    Alvaro Avezum
    Dante Pazzanese Cardiology Institute, Research Division, Sao Paulo, Brazil
    Am Heart J 149:67-73. 2005
    ..Evidence-based cardiac therapies are underutilized in elderly patients. We assessed differences in practice patterns, comorbidities, and in-hospital event rates, by age and type of acute coronary syndrome (ACS)...
  101. ncbi request reprint Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience
    Santi Trimarchi
    Istituto Policlinico S Donato, Milanese, Italy
    J Thorac Cardiovasc Surg 129:112-22. 2005
    ....