Ivan O Medvedev

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice
    Ivan O Medvedev
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Psychopharmacology (Berl) 180:408-13. 2005
  2. doi request reprint Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine
    Amy J Ramsey
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 33:2701-14. 2008
  3. pmc Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 105:4405-10. 2008
  4. pmc D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice
    Ivan O Medvedev
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, 16163 Genova, Italy, Skolkovo Institute of Science and Technology, Skolkovo, Moscow Region, 143025, Russia, Faculty of Biology and Soil Science, St Petersburg State University, St Petersburg 199034, Russia, and Department of Psychiatry and Neuroscience, Faculty of Medicine, Laval University and Institut universitaire en santé mentale de Québec, Quebec City, Quebec G1J 2G3, Canada
    J Neurosci 33:18125-33. 2013
  5. doi request reprint A beta-arrestin 2 signaling complex mediates lithium action on behavior
    Jean Martin Beaulieu
    Department of Cell Biology, Duke University Medical Center, Durham, NC, USA
    Cell 132:125-36. 2008
  6. ncbi request reprint Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Psychiatry 61:65-9. 2007
  7. pmc The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse
    Jacob P R Jacobsen
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Philos Trans R Soc Lond B Biol Sci 367:2444-59. 2012
  8. ncbi request reprint Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice
    Laura M Bohn
    Department of Pharmacology, The Ohio State University College of Medicine and Public Health, Columbus, Ohio 43210, USA
    J Neurosci 23:10265-73. 2003

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice
    Ivan O Medvedev
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Psychopharmacology (Berl) 180:408-13. 2005
    ..The dopamine transporter (DAT) is thought to play a major role in the rewarding effects of cocaine. Therefore, it is surprising that cocaine reveals conditioned effects in DAT knockout (DAT-KO) mice...
  2. doi request reprint Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine
    Amy J Ramsey
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 33:2701-14. 2008
    ....
  3. pmc Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 105:4405-10. 2008
    ..2 and 0.5 mg/kg) than WT mice (2 mg/kg). These results suggest that overexpression of DAT leads to a marked increase in sensitivity to psychomotor and rewarding properties of amphetamine...
  4. pmc D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice
    Ivan O Medvedev
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, 16163 Genova, Italy, Skolkovo Institute of Science and Technology, Skolkovo, Moscow Region, 143025, Russia, Faculty of Biology and Soil Science, St Petersburg State University, St Petersburg 199034, Russia, and Department of Psychiatry and Neuroscience, Faculty of Medicine, Laval University and Institut universitaire en santé mentale de Québec, Quebec City, Quebec G1J 2G3, Canada
    J Neurosci 33:18125-33. 2013
    ....
  5. doi request reprint A beta-arrestin 2 signaling complex mediates lithium action on behavior
    Jean Martin Beaulieu
    Department of Cell Biology, Duke University Medical Center, Durham, NC, USA
    Cell 132:125-36. 2008
    ..These results point toward a pharmacological approach to modulating GPCR function that affects the formation of beta-arrestin-mediated signaling complexes...
  6. ncbi request reprint Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Psychiatry 61:65-9. 2007
    ..This study sought to determine the efficiency of local small interfering RNA (siRNA) injections, comparing this approach with animals generated through classical gene targeting...
  7. pmc The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse
    Jacob P R Jacobsen
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Philos Trans R Soc Lond B Biol Sci 367:2444-59. 2012
    ....
  8. ncbi request reprint Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice
    Laura M Bohn
    Department of Pharmacology, The Ohio State University College of Medicine and Public Health, Columbus, Ohio 43210, USA
    J Neurosci 23:10265-73. 2003
    ..Thus, beta(arr2) appears to play a more important role in the dopaminergic effects mediated by morphine than those induced by cocaine...