Ivan O Medvedev

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice
    Ivan O Medvedev
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Psychopharmacology (Berl) 180:408-13. 2005
  2. doi request reprint Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine
    Amy J Ramsey
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 33:2701-14. 2008
  3. pmc Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 105:4405-10. 2008
  4. doi request reprint A beta-arrestin 2 signaling complex mediates lithium action on behavior
    Jean Martin Beaulieu
    Department of Cell Biology, Duke University Medical Center, Durham, NC, USA
    Cell 132:125-36. 2008
  5. ncbi request reprint Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Psychiatry 61:65-9. 2007
  6. pmc The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse
    Jacob P R Jacobsen
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Philos Trans R Soc Lond B Biol Sci 367:2444-59. 2012
  7. ncbi request reprint Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice
    Laura M Bohn
    Department of Pharmacology, The Ohio State University College of Medicine and Public Health, Columbus, Ohio 43210, USA
    J Neurosci 23:10265-73. 2003

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice
    Ivan O Medvedev
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Psychopharmacology (Berl) 180:408-13. 2005
    ..The dopamine transporter (DAT) is thought to play a major role in the rewarding effects of cocaine. Therefore, it is surprising that cocaine reveals conditioned effects in DAT knockout (DAT-KO) mice...
  2. doi request reprint Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine
    Amy J Ramsey
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 33:2701-14. 2008
    ....
  3. pmc Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 105:4405-10. 2008
    ..2 and 0.5 mg/kg) than WT mice (2 mg/kg). These results suggest that overexpression of DAT leads to a marked increase in sensitivity to psychomotor and rewarding properties of amphetamine...
  4. doi request reprint A beta-arrestin 2 signaling complex mediates lithium action on behavior
    Jean Martin Beaulieu
    Department of Cell Biology, Duke University Medical Center, Durham, NC, USA
    Cell 132:125-36. 2008
    ..These results point toward a pharmacological approach to modulating GPCR function that affects the formation of beta-arrestin-mediated signaling complexes...
  5. ncbi request reprint Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals
    Ali Salahpour
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Psychiatry 61:65-9. 2007
    ..This study sought to determine the efficiency of local small interfering RNA (siRNA) injections, comparing this approach with animals generated through classical gene targeting...
  6. pmc The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse
    Jacob P R Jacobsen
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Philos Trans R Soc Lond B Biol Sci 367:2444-59. 2012
    ....
  7. ncbi request reprint Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice
    Laura M Bohn
    Department of Pharmacology, The Ohio State University College of Medicine and Public Health, Columbus, Ohio 43210, USA
    J Neurosci 23:10265-73. 2003
    ..Thus, beta(arr2) appears to play a more important role in the dopaminergic effects mediated by morphine than those induced by cocaine...