W H Meck

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint "Speed" warps time: methamphetamine's interactive roles in drug abuse, habit formation, and the biological clocks of circadian and interval timing
    Lauren L Williamson
    Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708, USA
    Curr Drug Abuse Rev 1:203-12. 2008
  2. ncbi request reprint Dissecting the brain's internal clock: how frontal-striatal circuitry keeps time and shifts attention
    Warren H Meck
    Department of Psychological and Brain Sciences, Duke University, Durham, NC 27708, USA
    Brain Cogn 48:195-211. 2002
  3. ncbi request reprint Not "just" a coincidence: frontal-striatal interactions in working memory and interval timing
    Cindy Lustig
    Washington University, St Louis, MO, USA
    Memory 13:441-8. 2005
  4. ncbi request reprint What makes us tick? Functional and neural mechanisms of interval timing
    Catalin V Buhusi
    Duke University, Department of Psychological and Brain Sciences, 103 Research Drive, GSRB 2 Building, Room 3010, Durham, North Carolina 27708, USA
    Nat Rev Neurosci 6:755-65. 2005
  5. ncbi request reprint Time sharing in rats: A peak-interval procedure with gaps and distracters
    Catalin V Buhusi
    Duke University, Department Psychological and Brain Sciences, Durham, NC 27708, USA
    Behav Processes 71:107-15. 2006
  6. pmc Acquisition of "Start" and "Stop" response thresholds in peak-interval timing is differentially sensitive to protein synthesis inhibition in the dorsal and ventral striatum
    Christopher J MacDonald
    Department of Psychology and Center for Memory and Brain, Boston University, Boston MA, USA
    Front Integr Neurosci 6:10. 2012
  7. pmc Unwinding the molecular basis of interval and circadian timing
    Patricia V Agostino
    Laboratorio de Cronobiologia, Departamento de Ciencia y Tecnologia, Universidad Nacional de Quilmes Buenos Aires, Argentina
    Front Integr Neurosci 5:64. 2011
  8. doi request reprint Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice
    Warren H Meck
    Department of Psychology and Neuroscience, Genome Sciences Research Building II 3rd Floor, 572 Research Drive Box 91050, Duke University, Durham, NC 27708, USA
    Neuropharmacology 62:1221-9. 2012
  9. ncbi request reprint Neuropsychology of timing and time perception
    Warren H Meck
    Department of Psychological and Brain Sciences, Genome Sciences Research Building II, 3rd Floor, 103 Research Drive, Box 91050, Duke University, Durham, NC 27708, United States
    Brain Cogn 58:1-8. 2005
  10. ncbi request reprint Neuropharmacology of timing and time perception
    W H Meck
    Department of Psychology Experimental, Duke University, Durham, NC 27708, USA
    Brain Res Cogn Brain Res 3:227-42. 1996

Detail Information

Publications57

  1. ncbi request reprint "Speed" warps time: methamphetamine's interactive roles in drug abuse, habit formation, and the biological clocks of circadian and interval timing
    Lauren L Williamson
    Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708, USA
    Curr Drug Abuse Rev 1:203-12. 2008
    ..The conclusion is that the psychostimulant properties of MAP are very much embedded within the context of temporal prediction and the anticipation of reward...
  2. ncbi request reprint Dissecting the brain's internal clock: how frontal-striatal circuitry keeps time and shifts attention
    Warren H Meck
    Department of Psychological and Brain Sciences, Duke University, Durham, NC 27708, USA
    Brain Cogn 48:195-211. 2002
    ....
  3. ncbi request reprint Not "just" a coincidence: frontal-striatal interactions in working memory and interval timing
    Cindy Lustig
    Washington University, St Louis, MO, USA
    Memory 13:441-8. 2005
    ..The principles derived from these biologically based models also fit well with a family of behaviourally based models that emphasise the importance of time in many working memory phenomena...
  4. ncbi request reprint What makes us tick? Functional and neural mechanisms of interval timing
    Catalin V Buhusi
    Duke University, Department of Psychological and Brain Sciences, 103 Research Drive, GSRB 2 Building, Room 3010, Durham, North Carolina 27708, USA
    Nat Rev Neurosci 6:755-65. 2005
    ..However, recent advances have challenged this traditional view. It is now proposed that the brain represents time in a distributed manner and tells the time by detecting the coincidental activation of different neural populations...
  5. ncbi request reprint Time sharing in rats: A peak-interval procedure with gaps and distracters
    Catalin V Buhusi
    Duke University, Department Psychological and Brain Sciences, Durham, NC 27708, USA
    Behav Processes 71:107-15. 2006
    ..Computer simulations show that when combined, the memory-decay and time-sharing hypotheses can mechanistically address present data, suggesting that these two hypotheses may reflect different levels of analysis of the same phenomenon...
  6. pmc Acquisition of "Start" and "Stop" response thresholds in peak-interval timing is differentially sensitive to protein synthesis inhibition in the dorsal and ventral striatum
    Christopher J MacDonald
    Department of Psychology and Center for Memory and Brain, Boston University, Boston MA, USA
    Front Integr Neurosci 6:10. 2012
    ..We hypothesize that the dorsal and ventral regions of the striatum function as a competitive neural network that encodes the temporal boundaries marking the beginning and end of a timed response sequence...
  7. pmc Unwinding the molecular basis of interval and circadian timing
    Patricia V Agostino
    Laboratorio de Cronobiologia, Departamento de Ciencia y Tecnologia, Universidad Nacional de Quilmes Buenos Aires, Argentina
    Front Integr Neurosci 5:64. 2011
    ..While there is currently no common neurochemical substrate for timing mechanisms in the brain, circadian modulation of interval timing suggests an interaction of different frequencies in cerebral temporal processes...
  8. doi request reprint Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice
    Warren H Meck
    Department of Psychology and Neuroscience, Genome Sciences Research Building II 3rd Floor, 572 Research Drive Box 91050, Duke University, Durham, NC 27708, USA
    Neuropharmacology 62:1221-9. 2012
    ..Taken together, these results demonstrate the importance of dopaminergic control of interval timing in cortico-striatal circuits and the potential link of timing dysfunctions to schizophrenia and drug abuse...
  9. ncbi request reprint Neuropsychology of timing and time perception
    Warren H Meck
    Department of Psychological and Brain Sciences, Genome Sciences Research Building II, 3rd Floor, 103 Research Drive, Box 91050, Duke University, Durham, NC 27708, United States
    Brain Cogn 58:1-8. 2005
    ..The conclusion is that the representation of time depends on the integration of multiple neural systems that can be fruitfully studied in selected patient populations...
  10. ncbi request reprint Neuropharmacology of timing and time perception
    W H Meck
    Department of Psychology Experimental, Duke University, Durham, NC 27708, USA
    Brain Res Cogn Brain Res 3:227-42. 1996
    ..These two systems are connected by frontal-striatal loops, thus allowing for the completion of the timing sequences involved in duration discrimination...
  11. ncbi request reprint Frontal cortex lesions eliminate the clock speed effect of dopaminergic drugs on interval timing
    Warren H Meck
    Department of Psychology and Neuroscience, Duke University, 572 Research Drive, Genome Sciences Research Building II Box 91050, Durham, NC 27708 0086, USA
    Brain Res 1108:157-67. 2006
    ....
  12. ncbi request reprint Amygdala inactivation reverses fear's ability to impair divided attention and make time stand still
    Warren H Meck
    Department of Psychology and Neuroscience, Duke University, 572 Research Drive, Durham, NC 27708, USA
    Behav Neurosci 121:707-20. 2007
    ....
  13. ncbi request reprint Neuroanatomical localization of an internal clock: a functional link between mesolimbic, nigrostriatal, and mesocortical dopaminergic systems
    Warren H Meck
    Department of Psychology and Neuroscience, Duke University, 572 Research Drive, Genome Sciences Research Building II Box 91050, Durham, NC 27708, USA
    Brain Res 1109:93-107. 2006
    ....
  14. doi request reprint Cortico-striatal representation of time in animals and humans
    Warren H Meck
    Department of Psychology and Neuroscience, Duke University, Durham, NC 27708 0086, USA
    Curr Opin Neurobiol 18:145-52. 2008
    ..The conclusion is that although the striatum serves as a 'core timer', it is part of a distributed timing system involving the coordination of large-scale oscillatory networks...
  15. ncbi request reprint Temporal memory in mature and aged rats is sensitive to choline acetyltransferase inhibition
    Warren H Meck
    Department of Psychology and Neuroscience, Duke University, 572 Research Drive, Genome Sciences Research Building II Box 91050, Durham, NC 27708, USA
    Brain Res 1108:168-75. 2006
    ..Taken together, these results demonstrate that both working and reference memory for temporal information are sensitive to choline acetyltransferase inhibition in rats...
  16. ncbi request reprint Acute ethanol potentiates the clock-speed enhancing effects of nicotine on timing and temporal memory
    Warren H Meck
    Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708, USA
    Alcohol Clin Exp Res 31:2106-13. 2007
    ..The present investigation assessed the ability of ethanol to potentiate nicotine's effect on the overestimation of multisecond durations as a result of an increase in the speed of an internal clock...
  17. ncbi request reprint Choline supplementation during prenatal development reduces proactive interference in spatial memory
    W H Meck
    Department of Psychology Experimental, Duke University, 9 Flowers Drive, Durham, NC 27708, USA
    Brain Res Dev Brain Res 118:51-9. 1999
    ....
  18. ncbi request reprint Metabolic imprinting of choline by its availability during gestation: implications for memory and attentional processing across the lifespan
    Warren H Meck
    Department of Psychological and Brain Sciences, Duke University, 9 Flowers Drive, Box 90086, Durham, NC 27708 0086, USA
    Neurosci Biobehav Rev 27:385-99. 2003
    ..We propose that this organizational effect of choline availability may be due to relatively permanent alterations in the functioning of the cholinergic synapse, which we have called 'metabolic imprinting'...
  19. doi request reprint Prenatal-choline supplementation differentially modulates timing of auditory and visual stimuli in aged rats
    Ruey Kuang Cheng
    Department of Psychology and Neuroscience, Duke University, 572 Research Drive, Durham, NC 27708, USA
    Brain Res 1237:167-75. 2008
    ..Overall, these results suggest that prenatal-choline supplementation impacts interval timing by enhancing the differences in temporal integration between auditory and visual stimuli in aged subjects...
  20. pmc Prenatal choline supplementation alters the timing, emotion, and memory performance (TEMP) of adult male and female rats as indexed by differential reinforcement of low-rate schedule behavior
    Ruey Kuang Cheng
    Department of Psychology and Neuroscience, Duke University, Genome Sciences Research Building II, Durham, North Carolina 27708, USA
    Learn Mem 15:153-62. 2008
    ....
  21. pmc alpha7 Nicotinic acetylcholine receptors and temporal memory: synergistic effects of combining prenatal choline and nicotine on reinforcement-induced resetting of an interval clock
    Ruey Kuang Cheng
    Department of Psychological and Brain Sciences, Duke University, Durham, North Carolina 27708, USA
    Learn Mem 13:127-34. 2006
    ..The synergistic effect of combining prenatal CHO and NIC treatments suggests an organizational change in alpha7 nAChR function that is dependent upon a combination of selective and nonselective nAChR stimulation during early development...
  22. ncbi request reprint Hypertrophy of basal forebrain neurons and enhanced visuospatial memory in perinatally choline-supplemented rats
    C L Williams
    Department of Psychology Experimental, Duke University, Box 90086, Durham, NC 27708, USA
    Brain Res 794:225-38. 1998
    ....
  23. pmc Prenatal choline supplementation increases sensitivity to time by reducing non-scalar sources of variance in adult temporal processing
    Ruey Kuang Cheng
    Department of Psychology and Neuroscience, 572 Research Drive, Duke University, Durham, NC 27708, USA
    Brain Res 1186:242-54. 2007
    ..Overall, these results suggest that prenatal choline supplementation facilitates timing by reducing impulsive responding early in the interval, thereby improving the superimposition of peak functions for different temporal criteria...
  24. ncbi request reprint Impairments in timing, temporal memory, and reversal learning linked to neurotoxic regimens of methamphetamine intoxication
    Ruey Kuang Cheng
    Department of Psychology and Neuroscience, 572 Research Drive, Duke University, Durham, NC 27708, USA
    Brain Res 1186:255-66. 2007
    ....
  25. doi request reprint Oscillatory bands, neuronal synchrony and hippocampal function: implications of the effects of prenatal choline supplementation for sleep-dependent memory consolidation
    Ruey Kuang Cheng
    Department of Psychology and Neuroscience, 572 Research Drive, Duke University, Durham, NC 27708, USA
    Brain Res 1237:176-94. 2008
    ..g., delta, theta, and gamma bands) and synchronization across multiple brain regions in relation to sleep-dependent memory consolidation in the hippocampus...
  26. ncbi request reprint Systems-level integration of interval timing and reaction time
    Christopher J MacDonald
    Department of Psychological and Brain Sciences, Genome Sciences Research Building II, 103 Research Drive Duke University, Box 91050, NC 27708, USA
    Neurosci Biobehav Rev 28:747-69. 2004
    ..Our conclusion is that interval timing and RT processes are in fact two sides of the same coin...
  27. ncbi request reprint Temporal integration as a function of signal and gap intensity in rats (Rattus norvegicus) and pigeons (Columba livia)
    Catalin V Buhusi
    Department of Psychological and Brain Sciences, Duke University, Durham, North Carolina 27708 0086, USA
    J Comp Psychol 116:381-90. 2002
    ..These results also suggest that both species use similar interval-timing mechanisms, influenced by nontemporal characteristics of the signal and gap...
  28. ncbi request reprint Ketamine "unlocks" the reduced clock-speed effects of cocaine following extended training: evidence for dopamine--glutamate interactions in timing and time perception
    Ruey Kuang Cheng
    Department of Psychology and Neuroscience, Duke University, 572 Research Drive, Genome Sciences Research Building II, Box 91050, Durham, NC 27708, USA
    Neurobiol Learn Mem 88:149-59. 2007
    ..A glutamate "lock/unlock" hypothesis is used to explain the observed dopamine-glutamate interactions as a function of timing behaviors becoming learned habits...
  29. ncbi request reprint Interaction of raclopride and preparatory interval effects on simple reaction time performance
    Christopher J MacDonald
    Department of Psychology and Neuroscience, Genome Sciences Research Building II, 3rd Floor, 572 Research Drive, Box 91050, Duke University, Durham, NC 27708, United States
    Behav Brain Res 175:62-74. 2006
    ..These results are discussed within the context of neuropsychological models of interval timing and support an underlying role for cortico-striatal dopaminergic function in temporal processing and simple RT measurements...
  30. pmc Electrophysiological measures of time processing in infant and adult brains: Weber's Law holds
    Elizabeth M Brannon
    Center for Cognitive Neuroscience, Duke University, Durham, NC 27708, USA
    J Cogn Neurosci 20:193-203. 2008
    ..Moreover, when absolute values were varied and ratio was held constant, the mismatch negativity did not vary...
  31. pmc Prenatal choline availability alters the context sensitivity of Pavlovian conditioning in adult rats
    Jeffrey A Lamoureux
    Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708, USA
    Learn Mem 15:866-75. 2008
    ..These data support the view that configural associations that rely on hippocampal function are selectively sensitive to prenatal manipulations of dietary choline during prenatal development...
  32. pmc Effect of clozapine on interval timing and working memory for time in the peak-interval procedure with gaps
    Catalin V Buhusi
    Duke University, Department of Psychology and Neuroscience, Durham, NC 27708, United States
    Behav Processes 74:159-67. 2007
    ..These results suggest that clozapine exerts effects in different brain areas in a manner that allows for the pharmacological separation of clock speed and working memory as a function of peak trials without and with gaps...
  33. ncbi request reprint Interval timing and the encoding of signal duration by ensembles of cortical and striatal neurons
    Matthew S Matell
    Department of Psychological and Brain Sciences, Duke University, USA
    Behav Neurosci 117:760-73. 2003
    ..Results suggest that striatal and cortical neurons encode specific durations in their firing rate and thereby serve as components of a neural circuit used to represent duration...
  34. ncbi request reprint Timing in the baby brain
    Elizabeth M Brannon
    Center for Cognitive Neuroscience, Duke University, Box 90999, Durham, NC 27708 0999, USA
    Brain Res Cogn Brain Res 21:227-33. 2004
    ..These results suggest that the 10-month-old infant brain has already developed some of the same mechanisms as adults for detecting deviations in the timing of stimulus events...
  35. ncbi request reprint Memory for timing visual and auditory signals in albino and pigmented rats
    Catalin V Buhusi
    Department of Psychological and Brain Sciences, Duke University, Durham, NC 27708, USA
    J Exp Psychol Anim Behav Process 31:18-30. 2005
    ....
  36. ncbi request reprint Differential effects of clozapine and haloperidol on interval timing in the supraseconds range
    Christopher J MacDonald
    Department of Psychological and Brain Sciences, Duke University, Genome Sciences Research Building II, 3rd Floor, P O Box 91050, Durham, NC 27708, USA
    Psychopharmacology (Berl) 182:232-44. 2005
    ....
  37. ncbi request reprint Interval timing with gaps and distracters: evaluation of the ambiguity, switch, and time-sharing hypotheses
    Catalin V Buhusi
    Department of Psychological and Brain Sciences, Duke University, Durham, NC 27708 91050, USA
    J Exp Psychol Anim Behav Process 32:329-38. 2006
    ..Computer simulations show that the time-sharing and memory-decay hypotheses can mechanistically address present data, and reflect different levels of the same model...
  38. ncbi request reprint Timing for the absence of a stimulus: the gap paradigm reversed
    C V Buhusi
    Department of Psychology, Experimental, Duke University, Durham, North Carolina 27708 0086, USA
    J Exp Psychol Anim Behav Process 26:305-22. 2000
    ..Results suggest that attentional mechanisms involving the salience or content of the gap might contribute to the response rule adopted in a gap procedure...
  39. pmc Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero
    Sarah J E Wong-Goodrich
    Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA
    Brain Res 1237:153-66. 2008
    ..Taken together, these findings suggest that the in utero availability of an essential nutrient, choline, causes differential behavioral and neuroplastic sensitivity to the adult choline supply...
  40. ncbi request reprint Transdermal nicotine effects on attention
    E D Levin
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Psychopharmacology (Berl) 140:135-41. 1998
    ..This study shows that, in addition to reducing attentional impairment, nicotine administered via transdermal patches can improve attentiveness in normal adult non-smokers...
  41. ncbi request reprint Combined organizational and activational effects of short and long photoperiods on spatial and temporal memory in rats
    Christopher J MacDonald
    Department of Psychology and Neuroscience, Genome Sciences Research Building II, 3rd Floor, 572 Research Drive, Box 91050, Duke University, Durham, NC 27708, USA
    Behav Processes 74:226-33. 2007
    ..The conclusion is that both spatial and temporal memory are sensitive to photoperiod variation in laboratory rats in a manner similar to that previously observed for reproductive behaviour...
  42. ncbi request reprint Habit formation and the loss of control of an internal clock: inverse relationship between the level of baseline training and the clock-speed enhancing effects of methamphetamine
    Ruey Kuang Cheng
    Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA
    Psychopharmacology (Berl) 193:351-62. 2007
    ..How this relationship changes as a function of repeated experience with the reinforcement contingencies and the gradual adaptation of the underlying neural circuits remains unclear...
  43. doi request reprint Quinpirole-induced sensitization to noisy/sparse periodic input: temporal synchronization as a component of obsessive-compulsive disorder
    B M Gu
    Department of Psychology and Neuroscience, Genome Sciences Research Building II, 572 Research Drive, Duke University, Durham, NC 27708, USA
    Neuroscience 179:143-50. 2011
    ..Parallels between quinpirole-induced rhythmical behavior and the repetitive motor habits frequently observed in obsessive-compulsive disorder are discussed...
  44. ncbi request reprint Differential effects of methamphetamine and haloperidol on the control of an internal clock
    Catalin V Buhusi
    Department of Psychological and Brain Sciences, Duke University Durham, North Carolina 27708 0086, USA
    Behav Neurosci 116:291-7. 2002
    ..This is the first report of both clock and attentional effects of dopaminergic drugs on interval timing in the same experimental setting...
  45. pmc Taste-guided decisions differentially engage neuronal ensembles across gustatory cortices
    Christopher J MacDonald
    Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708, USA
    J Neurosci 29:11271-82. 2009
    ..These results indicate that during a taste-guided decision task both primary and secondary gustatory cortices dynamically encode different types of information...
  46. ncbi request reprint Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation
    Tiffany J Mellott
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    FASEB J 18:545-7. 2004
    ....
  47. ncbi request reprint Cortico-striatal circuits and interval timing: coincidence detection of oscillatory processes
    Matthew S Matell
    Department of Psychology, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, USA
    Brain Res Cogn Brain Res 21:139-70. 2004
    ....
  48. ncbi request reprint Frontal-striatal circuitry activated by human peak-interval timing in the supra-seconds range
    Sean C Hinton
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Brain Res Cogn Brain Res 21:171-82. 2004
    ....
  49. ncbi request reprint Auditory/visual duration bisection in patients with left or right medial-temporal lobe resection
    Manuela Melgire
    Unité de Neurosciences Cognitives et d Imagerie Cérébrale, CNRS, UPR 640, Paris, France
    Brain Cogn 58:119-24. 2005
    ..These findings suggest the involvement of the right temporal lobe at the level of the decision process in temporal discriminations...
  50. ncbi request reprint Interval-timing deficits in individuals at high risk for schizophrenia
    Trevor B Penney
    Department of Psychology, Chinese University of Hong Kong, Shatin, N T, Hong Kong, Hong Kong
    Brain Cogn 58:109-18. 2005
    ..This attentionally mediated clock rate difference was larger for the HrSz participants than for the NC participants, resulting in a larger auditory/visual difference for the HrSz group...
  51. ncbi request reprint How emotions colour our perception of time
    Sylvie Droit-Volet
    Laboratoire de Psychologie Sociale et Cognitive, CNRS UMR 6024, Universite Blaise Pascal, 34 Avenue Carnot, 63037, Clermont Ferrand, France
    Trends Cogn Sci 11:504-13. 2007
    ..The study of time and emotion is at a crossroads, and we outline possible examples for future directions...
  52. ncbi request reprint Chronic treatment with haloperidol induces deficits in working memory and feedback effects of interval timing
    Cindy Lustig
    Department of Psychology, University of Michigan, United States
    Brain Cogn 58:9-16. 2005
    ....
  53. ncbi request reprint Single-trials analyses demonstrate that increases in clock speed contribute to the methamphetamine-induced horizontal shifts in peak-interval timing functions
    Matthew S Matell
    Department of Psychology, Villanova University, 800 Lancaster Avenue, Villanova, PA, 19085, USA
    Psychopharmacology (Berl) 188:201-12. 2006
    ..However, the generality of these results has been inconsistent in the literature...
  54. ncbi request reprint Sensory modality and time perception in children and adults
    Sylvie Droit-Volet
    Laboratoire de Psychologie Sociale et Cognitive, CNRS, UMR 6024, Blaise Pascal University of Clermont FD, 34 Avenue Carnot, 63000, Clermont Ferrand, France
    Behav Processes 74:244-50. 2007
    ..Specifically, although timing is more automatic for auditory than visual signals in both children and young adults, children have greater difficulty in keeping the switch in the closed state during the timing of visual signals...
  55. ncbi request reprint Differential modulation of clock speed by the administration of intermittent versus continuous cocaine
    Matthew S Matell
    Department of Neurology, University of Michigan Medical School, MI, USA
    Behav Neurosci 118:150-6. 2004
    ..Continuous cocaine administration produced no reliable effects. These results suggest that the mechanisms of sensitization may play a considerable role in drug-induced alterations of the perception of time...
  56. ncbi request reprint Neuroimaging of interval timing
    Warren H Meck
    Brain Res Cogn Brain Res 21:133-7. 2004
    ....