Research Topics
| Ross McKinneySummaryAffiliation: Duke University Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021Ross E McKinney
Department of Pediatrics, Duke University Medical Center, Box 3461, Durham, NC 27710, USA
Pediatrics 120:e416-23. 2007..Compliance with complex antiretroviral therapy regimens is a problem for HIV-1-infected children and their families. Simple, safe, and effective regimens are important for long-term therapeutic success...
Should an institution that has commercial rights in a new drug or device be allowed to evaluate the technology?Ross McKinney
Duke University School of Medicine, Durham, North Carolina, USA
PLoS Med 2:e9. 2005..Although this financial incentive can stimulate academic researchers to discover new drugs and devices, there is concern that the possibility of monetary reward could distort investigators' objectivity...
Congress, the FDA, and the fair development of new medications for childrenRoss E McKinney
Department of Pediatrics, Division of Infectious Diseases, Duke University School of Medicine, Durham, NC 27710, USA
Pediatrics 112:669-70. 2003
Newer treatments for HIV in childrenRoss E McKinney
Departmentof Pedicatrics, Duke University Medical Center, Durham, North Carolina 27710, USA
Curr Opin Pediatr 16:76-9. 2004..Several new antiretroviral agents have been introduced into pediatric and adult use. This review will summarize information about these new agents and other recent advances in the care of HIV-infected children...
Growth as a part of the composite endpoint in paediatric antiretroviral clinical trialsDaniel K Benjamin
Department of Pediatrics, Duke University, Durham, NC, USA
J Antimicrob Chemother 54:701-3. 2004....
Growth, survival and viral load in symptomatic childhood human immunodeficiency virus infectionCaroline J Chantry
Department of Pediatrics, University of California Davis Medical Center, Sacramento 95817, USA
Pediatr Infect Dis J 22:1033-9. 2003..The relationships among weight and height growth, viral load and survival in HIV-infected children remain unclear...
Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infectionKumud K Singh
Department of Pediatrics, Division of Infectious Diseases, University of California, San Diego, La Jolla, California 92093 0672, USA
J Infect Dis 188:1461-72. 2003..These data suggest that, in children, host genetics plays an important role in HIV-1-related disease progression and neurological impairment...
A comparison of height and weight velocity as a part of the composite endpoint in pediatric HIVDaniel K Benjamin
Duke Clinical Research Institute and the Department of Pediatrics, Duke University, Durham, North Carolina, USA
AIDS 17:2331-6. 2003..Changes in WAZ were not associated with laboratory outcomes relevant to pediatric HIV infection. Height velocity should be considered as a component of a composite clinical endpoint in future PACTG trials...
Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United StatesKumud K Singh
Department of Pediatrics, Division of Infectious Diseases, University of California at San Diego, La Jolla 92093 0672, USA
J Acquir Immune Defic Syndr 35:309-13. 2004..These analyses show that the distribution of chemokine receptor and chemokine genetic polymorphisms varies significantly across race/ethnicity subgroups of HIV-1-infected children in the United States...
Population pharmacokinetics and pharmacodynamics of zidovudine in HIV-infected infants and childrenEdmund V Capparelli
University of California, San Diego, School of Medicine, La Jolla, California, USA
J Clin Pharmacol 43:133-40. 2003..It was concluded that ZDV oral clearance is reduced in infants compared to older children. This lower clearance leads to higher ZDV exposure in infants and contributes to increased hematologic toxicity...
Shooting at a moving target: natural history studies and the rapidly improving state of anti-HIV treatmentRoss E McKinney
J Pediatr 141:301-2. 2002
Research Grants
- North Carolina Collaborative PPRU NetworkRoss McKinney; Fiscal Year: 2004..6) To train physicians and pharmacologists in clinical and developmental pharmacology: the centerpiece will be a 3-year pediatric pharmacology fellowship. Drs. Brouwer and Lindley (UNC) will lead this program. ..
- Integrated Human Research Subjects Protection ProjectRoss McKinney; Fiscal Year: 2003..abstract_text> ..
