Paul L Martin

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Cord-blood transplants from unrelated donors in patients with Hurler's syndrome
    Susan L Staba
    Pediatric Stem Cell Transplant Program, Duke University Medical Center, Durham, NC 27710, USA
    N Engl J Med 350:1960-9. 2004
  2. ncbi request reprint Umbilical cord blood: a guide for primary care physicians
    Paul L Martin
    Duke University Medical Center, Durham, NC 27710, USA
    Am Fam Physician 84:661-6. 2011
  3. ncbi request reprint To stop or not to stop: how much support should be provided to mechanically ventilated pediatric bone marrow and stem cell transplant patients?
    Paul L Martin
    Pediatric Blood and Marrow Transplant Division, Duke University Medical Center, 2400 Pratt Street, Suite 1400, Durham, NC 27705, USA
    Respir Care Clin N Am 12:403-19. 2006
  4. pmc Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease
    Priti Tewari
    Pediatric Blood and Marrow Transplantation Program, Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Blood Marrow Transplant 18:1368-77. 2012
  5. doi request reprint Unrelated donor umbilical cord blood transplantation in pediatric myelodysplastic syndrome: a single-center experience
    Suhag H Parikh
    Division of Pediatric Blood and Marrow Transplantation, Duke University Medical Center, Durham, North Carolina 27705, USA
    Biol Blood Marrow Transplant 15:948-55. 2009
  6. ncbi request reprint Outcomes of unrelated umbilical cord blood transplantation for X-linked adrenoleukodystrophy
    Donald Beam
    Department of Pediatrics, Division of Pediatric Blood and Marrow Transplantation, Duke University Medical Center, Durham, NC, USA
    Biol Blood Marrow Transplant 13:665-74. 2007
  7. pmc Posttransplant autoimmune hemolytic anemia and other autoimmune cytopenias are increased in very young infants undergoing unrelated donor umbilical cord blood transplantation
    Kristin M Page
    Department of Pediatrics, Division of Blood and Marrow Transplant, Duke University Medical Center, Durham, NC 27710, USA
    Biol Blood Marrow Transplant 14:1108-17. 2008
  8. pmc Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes
    Vinod K Prasad
    Pediatric Blood and Marrow Transplant Program, Duke University Medical Center, Durham, NC, USA
    Blood 112:2979-89. 2008
  9. ncbi request reprint Correction of chronic granulomatous disease after second unrelated-donor umbilical cord blood transplantation
    Suhag H Parikh
    Division of Pediatric Blood and Marrow Transplantation, Duke University Medical Center, Durham, North Carolina 27705, USA
    Pediatr Blood Cancer 49:982-4. 2007
  10. ncbi request reprint Results of the cord blood transplantation study (COBLT): outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with lysosomal and peroxisomal storage diseases
    Paul L Martin
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Blood Marrow Transplant 12:184-94. 2006

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Cord-blood transplants from unrelated donors in patients with Hurler's syndrome
    Susan L Staba
    Pediatric Stem Cell Transplant Program, Duke University Medical Center, Durham, NC 27710, USA
    N Engl J Med 350:1960-9. 2004
    ..We investigated the feasibility of using cord-blood transplants from unrelated donors and a myeloablative preparative regimen that did not involve total-body irradiation in young children with Hurler's syndrome...
  2. ncbi request reprint Umbilical cord blood: a guide for primary care physicians
    Paul L Martin
    Duke University Medical Center, Durham, NC 27710, USA
    Am Fam Physician 84:661-6. 2011
    ..Step-by-step guidance and electronic resources are available to physicians whose patients are considering saving or donating their infant's umbilical cord blood...
  3. ncbi request reprint To stop or not to stop: how much support should be provided to mechanically ventilated pediatric bone marrow and stem cell transplant patients?
    Paul L Martin
    Pediatric Blood and Marrow Transplant Division, Duke University Medical Center, 2400 Pratt Street, Suite 1400, Durham, NC 27705, USA
    Respir Care Clin N Am 12:403-19. 2006
    ..Of these potential therapies, the author is aware of only one multi-institutional study involving continuous venovenous hemodialysis at this time...
  4. pmc Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease
    Priti Tewari
    Pediatric Blood and Marrow Transplantation Program, Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Blood Marrow Transplant 18:1368-77. 2012
    ..Myeloablative hematopoietic stem cell transplantation led to correction of neutrophil dysfunction, durable donor chimerism, excellent survival, good quality of life, and low incidence of graft-vs-host disease regardless of graft source...
  5. doi request reprint Unrelated donor umbilical cord blood transplantation in pediatric myelodysplastic syndrome: a single-center experience
    Suhag H Parikh
    Division of Pediatric Blood and Marrow Transplantation, Duke University Medical Center, Durham, North Carolina 27705, USA
    Biol Blood Marrow Transplant 15:948-55. 2009
    ..UUCB should be actively considered for pediatric MDS patients lacking matched related or unrelated adult donors...
  6. ncbi request reprint Outcomes of unrelated umbilical cord blood transplantation for X-linked adrenoleukodystrophy
    Donald Beam
    Department of Pediatrics, Division of Pediatric Blood and Marrow Transplantation, Duke University Medical Center, Durham, NC, USA
    Biol Blood Marrow Transplant 13:665-74. 2007
    ..Superior outcomes were seen in neurologically asymptomatic boys less than 3.5 years of age at the time of transplantation. Baseline Loes scores were a strong predictor of cognitive and motor outcome...
  7. pmc Posttransplant autoimmune hemolytic anemia and other autoimmune cytopenias are increased in very young infants undergoing unrelated donor umbilical cord blood transplantation
    Kristin M Page
    Department of Pediatrics, Division of Blood and Marrow Transplant, Duke University Medical Center, Durham, NC 27710, USA
    Biol Blood Marrow Transplant 14:1108-17. 2008
    ..Alternative strategies to prevent GVHD should be considered for this unique patient population...
  8. pmc Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes
    Vinod K Prasad
    Pediatric Blood and Marrow Transplant Program, Duke University Medical Center, Durham, NC, USA
    Blood 112:2979-89. 2008
    ..1%-85.3%) in patients with high (80-100) performance score. In multivariate analysis, favorable factors for OS were high pretransplantation performance status, matched donor/recipient ethnicity, and higher infused colony forming units...
  9. ncbi request reprint Correction of chronic granulomatous disease after second unrelated-donor umbilical cord blood transplantation
    Suhag H Parikh
    Division of Pediatric Blood and Marrow Transplantation, Duke University Medical Center, Durham, North Carolina 27705, USA
    Pediatr Blood Cancer 49:982-4. 2007
    ..In conclusion, uUCBT is effective in children with CGD, but immunosuppression in the conditioning regimen may need to be increased to decrease the risk of graft rejection...
  10. ncbi request reprint Results of the cord blood transplantation study (COBLT): outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with lysosomal and peroxisomal storage diseases
    Paul L Martin
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Biol Blood Marrow Transplant 12:184-94. 2006
    ..Cord blood donors are readily available for rapid transplantation. Cord blood transplantation should be considered as frontline therapy for young patients with lysosomal and peroxisomal storage diseases...
  11. pmc A novel reduced-intensity conditioning regimen for unrelated umbilical cord blood transplantation in children with nonmalignant diseases
    Suhag H Parikh
    Pediatric Blood and Marrow Transplantation Program, Duke University Medical Center, Durham, North Carolina Electronic address
    Biol Blood Marrow Transplant 20:326-36. 2014
    ..This is the first RIC protocol demonstrating durable UCB engraftment in children with NMD. Future risk-based modifications of this regimen could decrease the incidence of viral infections. (www.clinicaltrials.gov/NCT00744692)...
  12. ncbi request reprint Mechanically ventilated pediatric stem cell transplant recipients: effect of cord blood transplant and organ dysfunction on outcome
    Scott A Hagen
    Division of Pediatric Critical Care Medicine, Duke University Medical Center, Durham, NC, USA
    Pediatr Crit Care Med 4:206-13. 2003
    ..To compare survival of pediatric umbilical cord blood and bone marrow transplant recipients requiring admission to a pediatric intensive care unit for mechanical ventilation and to determine the effect of organ dysfunction on outcome...
  13. ncbi request reprint Unrelated umbilical cord blood transplantation for an infant with beta-thalassemia major
    Jennifer G Hall
    Pediatric Bone Marrow and Stem Cell Transplant Program, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Pediatr Hematol Oncol 26:382-5. 2004
    ..This report describes the successful transplantation of a 2-month-old infant with beta-thalassemia major using partially HLA-matched unrelated umbilical cord blood...
  14. ncbi request reprint The incidence of testicular recurrence in boys with acute leukemia treated with total body and testicular irradiation and stem cell transplantation
    Brian P Quaranta
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Cancer 101:845-50. 2004
    ..The authors studied the incidence of testicular failure in a large series of male patients who underwent SCT using either TBI and a testicular irradiation boost or chemotherapy alone...
  15. ncbi request reprint High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas
    Sridharan Gururangan
    Brain Tumor Center at Duke and the Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Oncol 21:2187-91. 2003
    ..We evaluated the usefulness of a treatment regimen that included high-dose chemotherapy (HDC) with autologous stem-cell rescue (ASCR) in patients with newly diagnosed pineoblastoma (PBL)...
  16. ncbi request reprint Prospective Aspergillus galactomannan antigen testing in pediatric hematopoietic stem cell transplant recipients
    William J Steinbach
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Infect Dis J 26:558-64. 2007
    ..There have been few studies with this assay in pediatric patients, but early reports suggest that there may be differences in the performance such that false-positive GM tests in pediatric patients are more common than in adult patients...
  17. ncbi request reprint Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells: results of a phase 1 trial using the AastromReplicell System
    Jennifer Jaroscak
    Pediatric and Adult Bone Marrow Transplant Programs, Duke University Medical Center, Durham, NC 27710, USA
    Blood 101:5061-7. 2003
    ..A randomized phase 2 study will determine whether augmenting UCB transplants with ex vivo-expanded UCB cells is beneficial...
  18. ncbi request reprint Acute myelogenous leukemia associated with Ollier disease
    Matthew S White
    Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Pediatr Blood Cancer 50:645-6. 2008
    ..This report describes a patient with Ollier disease and AML and may offer a clue into the genetic pathogenesis of these disorders...
  19. pmc Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study
    Michael J Borowitz
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Blood 111:5477-85. 2008
    ..These studies are registered at www.clinicaltrials.gov as NCT00005585, NCT00005596, and NCT00005603...
  20. pmc Antimetabolite therapy for lesser-risk B-lineage acute lymphoblastic leukemia of childhood: a report from Children's Oncology Group Study P9201
    Allen R Chauvenet
    Department of Pediatrics, Wake Forest University Medical Center, Winston Salem, NC, USA
    Blood 110:1105-11. 2007
    ..Sex, ethnicity, CNS status, and WBC were not predictive. This indicates the great majority of children with lesser-risk B-lineage ALL are curable without agents with substantial late effects...
  21. ncbi request reprint Comparison of diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children's oncology group
    Michael J Borowitz
    Department of Pathology and Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cytometry B Clin Cytom 68:18-24. 2005
    ..However, little is known about how phenotypic shifts between diagnosis and relapse affect MRD detection in childhood acute lymphoid leukemia (ALL)...
  22. ncbi request reprint Marrow cell transplantation for infantile hypophosphatasia
    Michael P Whyte
    Center for Metabolic Bone Disease and Molecular Research, Shriners Hospitals for Children, St Louis, Missouri 63131 3597, USA
    J Bone Miner Res 18:624-36. 2003
    ....
  23. ncbi request reprint Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome
    Paul G Richardson
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Blood 100:4337-43. 2002
    ..Certain features associated with successful outcome may correlate with DF-related treatment effects, and prospective evaluation of DF therapy for severe VOD should allow better definition of predictors of response or failure...