D B Mark

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Exercise capacity: the prognostic variable that doesn't get enough respect
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 108:1534-6. 2003
  2. ncbi request reprint Medical economics and the assessment of value in cardiovascular medicine: Part I
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:516-20. 2002
  3. ncbi request reprint Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes
    D B Mark
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    Circulation 101:366-71. 2000
  4. ncbi request reprint Cardiovascular disease on a global scale: defining the path forward for research and practice
    Daniel B Mark
    Division of Cardiology, Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA
    Eur Heart J 28:2678-84. 2007
  5. doi request reprint Long-term economic outcomes associated with intensive versus moderate lipid-lowering therapy in coronary artery disease: results from the Treating to New Targets (TNT) Trial
    Daniel B Mark
    Outcomes Research Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 156:698-705. 2008
  6. ncbi request reprint Cost-effectiveness of defibrillator therapy or amiodarone in chronic stable heart failure: results from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    Daniel B Mark
    Outcomes Research Group, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Circulation 114:135-42. 2006
  7. pmc Quality of life and economic outcomes with surgical ventricular reconstruction in ischemic heart failure: results from the Surgical Treatment for Ischemic Heart Failure trial
    Daniel B Mark
    Outcomes Research Group, Duke University Medical Center, Durham, NC, USA
    Am Heart J 157:837-44, 844.e1-3. 2009
  8. ncbi request reprint Medical economics and the assessment of value in cardiovascular medicine: Part II
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:626-30. 2002
  9. pmc Quality of life effects of automatic external defibrillators in the home: results from the Home Automatic External Defibrillator Trial (HAT)
    Daniel B Mark
    Outcomes Research Group, Duke Clinical Research Institute PO Box 17969 Durham, NC 27715, USA
    Am Heart J 159:627-634.e7. 2010
  10. ncbi request reprint Cost effectiveness of early discharge after uncomplicated acute myocardial infarction
    L K Newby
    Duke Clinical Research Institute, Durham, NC 27715 7969, USA
    N Engl J Med 342:749-55. 2000

Detail Information

Publications111 found, 100 shown here

  1. ncbi request reprint Exercise capacity: the prognostic variable that doesn't get enough respect
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 108:1534-6. 2003
  2. ncbi request reprint Medical economics and the assessment of value in cardiovascular medicine: Part I
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:516-20. 2002
  3. ncbi request reprint Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes
    D B Mark
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    Circulation 101:366-71. 2000
    ..In the PURSUIT trial, eptifibatide significantly reduced the 30-day incidence of death and myocardial infarction relative to placebo in 9461 patients with an acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction)...
  4. ncbi request reprint Cardiovascular disease on a global scale: defining the path forward for research and practice
    Daniel B Mark
    Division of Cardiology, Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA
    Eur Heart J 28:2678-84. 2007
    ....
  5. doi request reprint Long-term economic outcomes associated with intensive versus moderate lipid-lowering therapy in coronary artery disease: results from the Treating to New Targets (TNT) Trial
    Daniel B Mark
    Outcomes Research Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 156:698-705. 2008
    ....
  6. ncbi request reprint Cost-effectiveness of defibrillator therapy or amiodarone in chronic stable heart failure: results from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    Daniel B Mark
    Outcomes Research Group, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Circulation 114:135-42. 2006
    ..We examined long-term economic implications of these results...
  7. pmc Quality of life and economic outcomes with surgical ventricular reconstruction in ischemic heart failure: results from the Surgical Treatment for Ischemic Heart Failure trial
    Daniel B Mark
    Outcomes Research Group, Duke University Medical Center, Durham, NC, USA
    Am Heart J 157:837-44, 844.e1-3. 2009
    ..The impact of SVR on quality of life (QOL) and medical costs is unknown...
  8. ncbi request reprint Medical economics and the assessment of value in cardiovascular medicine: Part II
    Daniel B Mark
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Circulation 106:626-30. 2002
  9. pmc Quality of life effects of automatic external defibrillators in the home: results from the Home Automatic External Defibrillator Trial (HAT)
    Daniel B Mark
    Outcomes Research Group, Duke Clinical Research Institute PO Box 17969 Durham, NC 27715, USA
    Am Heart J 159:627-634.e7. 2010
    ..Quality of life (QOL) outcomes for both the patient and spouse/companion were secondary end points...
  10. ncbi request reprint Cost effectiveness of early discharge after uncomplicated acute myocardial infarction
    L K Newby
    Duke Clinical Research Institute, Durham, NC 27715 7969, USA
    N Engl J Med 342:749-55. 2000
    ..Reducing the length of hospitalizations can reduce short-term costs, but there are few data on the long-term clinical and economic consequences of early discharge...
  11. ncbi request reprint Impact of early discharge after coronary artery bypass graft surgery on rates of hospital readmission and death. The Ischemic Heart Disease (IHD) Patient Outcomes Research Team (PORT) Investigators
    P A Cowper
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Cardiol 30:908-13. 1997
    ..This study examined the impact of early hospital discharge on short-term clinical outcomes of elderly patients treated with coronary artery bypass graft surgery (CABG) in the United States in 1992...
  12. ncbi request reprint Moderators of the effect of social support on depressive symptoms in cardiac patients
    J C Barefoot
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 86:438-42. 2000
    ..These findings also have implications for the design and interpretation of psychosocial interventions...
  13. ncbi request reprint Acute and long-term cost implications of coronary stenting
    E D Peterson
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 33:1610-8. 1999
    ..We compared the acute and one year medical costs and outcomes of coronary stenting with those for balloon angioplasty (percutaneous transluminal coronary angioplasty) in contemporary clinical practice...
  14. ncbi request reprint Social support and hostility as predictors of depressive symptoms in cardiac patients one month after hospitalization: a prospective study
    B H Brummett
    Behavioral Medicine Research Center and the Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
    Psychosom Med 60:707-13. 1998
    ....
  15. ncbi request reprint Use of a prognostic treadmill score in identifying diagnostic coronary disease subgroups
    L J Shaw
    Center For Cardiovascular Epidemiology, Division of Cardiology, Emory University, Atlanta, GA, USA
    Circulation 98:1622-30. 1998
    ..However, its usefulness for providing diagnostic estimates has yet to be determined...
  16. ncbi request reprint Assessing the clinical and economic burden of coronary artery disease: 1986-1998
    E L Eisenstein
    Outcomes Research and Assessment Group, The Duke Clincal Research Institute, Durham, NC, USA
    Med Care 39:824-35. 2001
    ..We compared the clinical and economic burden of CAD during the acute phase (first 30 days) with that in the postacute phase (31st day through 10 years)...
  17. ncbi request reprint Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery
    M F Newman
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    N Engl J Med 344:395-402. 2001
    ..We sought to determine the course of cognitive change during the five years after CABG and the effect of perioperative decline on long-term cognitive function...
  18. ncbi request reprint Relationship between diabetes mellitus and long-term survival after coronary bypass and angioplasty
    G W Barsness
    Duke Heart Center, Duke University Medical Center, Durham, NC, USA
    Circulation 96:2551-6. 1997
    ..We studied the relationship between diabetes and survival after revascularization in a large prospective cohort of patients with multivessel coronary artery disease...
  19. ncbi request reprint Economic analysis of the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT-3) study: costs of reperfusion strategies in acute myocardial infarction
    Padma Kaul
    Department of Medicine, Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 149:637-44. 2005
    ....
  20. ncbi request reprint Prospective study of perceived stress in cardiac patients
    Beverly H Brummett
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
    Ann Behav Med 27:22-30. 2004
    ..Although the study of stress CAD samples has received considerable attention, few studies have examined the effects of gender and age, had multiple follow-ups over an extended period, and had extensive baseline assessment batteries...
  21. ncbi request reprint Effects of stroke on medical resource use and costs in acute myocardial infarction. GUSTO I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries Study
    C Y Tung
    Duke Clinical Research Institute, Durham, NC, USA
    Circulation 99:370-6. 1999
    ..However, no data exist for the economic effect of stroke in the setting of acute MI (AMI). The purpose of this prospective study was to assess the effect of stroke on medical resource use and costs in AMI patients in the United States...
  22. ncbi request reprint Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery
    M F Newman
    Department of Anesthesiology, Division of Neurology, Duke University Medical Center, Durham, NC, USA
    Stroke 32:2874-81. 2001
    ..The purpose of our investigation was to determine the association between cognitive dysfunction and long-term quality of life after cardiac surgery...
  23. ncbi request reprint Using observational data to estimate prognosis: an example using a coronary artery disease registry
    E R DeLong
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Duke University, Department of Medicine, Biometry Division, Community and Family Medicine, 2400 Pratt Street, Durham, NC 27705, USA
    Stat Med 20:2505-32. 2001
    ..This paper discusses these issues and suggests strategies to deal with them. A proposed methodology is developed, applied and evaluated on a large observational database that has long-term follow-up on nearly 10 000 patients...
  24. ncbi request reprint Depressive symptoms and survival of patients with coronary artery disease
    J C Barefoot
    Behavioral Medicine Research Center, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
    Psychosom Med 62:790-5. 2000
    ..This investigation divided depressive symptoms into groups to assess their relative effectiveness in predicting survival...
  25. ncbi request reprint Value of exercise treadmill testing in women
    K P Alexander
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 32:1657-64. 1998
    ..We sought to determine the ability of a treadmill score to provide accurate diagnostic and prognostic risk estimates in women...
  26. ncbi request reprint The effects of New York's bypass surgery provider profiling on access to care and patient outcomes in the elderly
    E D Peterson
    Duke Clinical Research Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 32:993-9. 1998
    ..The aim of this study was to examine the effects of provider profiling on bypass surgery access and outcomes in elderly patients in New York...
  27. ncbi request reprint Economic assessment of low-molecular-weight heparin (enoxaparin) versus unfractionated heparin in acute coronary syndrome patients: results from the ESSENCE randomized trial. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q wave Coronary Events [un
    D B Mark
    Clinical Research Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Circulation 97:1702-7. 1998
    ..No increase in major bleeding was seen...
  28. ncbi request reprint The prognostic importance of comorbidity for mortality in patients with stable coronary artery disease
    Molly Sachdev
    Duke Clinical Research Institute, Duke University, Durham, North Carolina 27705, USA
    J Am Coll Cardiol 43:576-82. 2004
    ..To identify the prevalent and prognostically important coexisting illnesses among single coronary artery disease (CAD) patients...
  29. doi request reprint Evolution of the coronary care unit: clinical characteristics and temporal trends in healthcare delivery and outcomes
    Jason N Katz
    Department of Medicine, Division of Cardiology and Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    Crit Care Med 38:375-81. 2010
    ..To describe long-term temporal trends in patient characteristics, processes of care, and in-hospital outcomes among unselected admissions within the contemporary coronary care unit...
  30. ncbi request reprint Evaluating the potential 'economic attractiveness' of new therapies in patients with non-ST elevation acute coronary syndrome
    E L Eisenstein
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Pharmacoeconomics 17:263-72. 2000
    ..To evaluate the relationship between how much a new cardiovascular therapy improves clinical outcomes over current therapies and how much more it can cost while still remaining 'economically attractive'...
  31. ncbi request reprint Personality and coping with a common stressor: cardiac catheterization
    H B Bosworth
    Health Services Research and Development, Durham VAMC, Building 16, Room 70, 508 Fulton St, Durham, NC 27705, USA
    J Behav Med 24:17-31. 2001
    ....
  32. ncbi request reprint Perception of cognitive function in older adults following coronary artery bypass surgery
    P Khatri
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
    Health Psychol 18:301-6. 1999
    ..Interventions designed to reduce emotional distress could improve patient's perceived cognitive abilities following CABG...
  33. pmc Quality of life after late invasive therapy for occluded arteries
    Daniel B Mark
    Outcomes Research Group, Duke Clinical Research Institute, and the Department of Medicine, Duke University Medical Center, Durham, NC, USA
    N Engl J Med 360:774-83. 2009
    ..We evaluated the quality-of-life and economic outcomes associated with the use of this strategy...
  34. ncbi request reprint Risk of thromboembolism in heart failure: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    Ronald S Freudenberger
    Department of Medicine, Robert Wood Johnson Medical School, Suite 6100, 125 Paterson St, New Brunswick, NJ 08903, USA
    Circulation 115:2637-41. 2007
    ..In the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT), 2521 patients with moderate heart failure were randomized to receive amiodarone, implanted cardioverter-defibrillators (ICDs), or placebo...
  35. ncbi request reprint Clinical and economic implications of the Multicenter Automatic Defibrillator Implantation Trial-II
    Sana M Al-Khatib
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    Ann Intern Med 142:593-600. 2005
    ..3 or less...
  36. ncbi request reprint What is the economic value of digoxin therapy in congestive heart failure patients? Results from the DIG trial
    Eric L Eisenstein
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Card Fail 12:336-42. 2006
    ..At 37 months average follow-up, patients in both groups had similar mortality. We determined the incremental costs associated with the use of digoxin in this high-risk population...
  37. ncbi request reprint Impact of rate-modulated pacing on quality of life and exercise capacity--evidence from the Advanced Elements of Pacing Randomized Controlled Trial (ADEPT)
    Gervasio A Lamas
    Division of Cardiology, Mount Sinai Medical Center, Miami Beach, Florida 33140, USA
    Heart Rhythm 4:1125-32. 2007
    ..Ninety-nine percent of pacemakers implanted in the United States include an option for rate modulation...
  38. pmc Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, SC 29425 5920, USA
    Circulation 118:2022-8. 2008
    ....
  39. ncbi request reprint Advanced coronary artery disease: Appropriate end points for trials of novel therapies
    D E Kandzari
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 142:843-51. 2001
    ..Because the natural history of these patients is less defined, the appropriate end points for trials of novel revascularization therapies involving patients with advanced coronary artery disease are not certain...
  40. ncbi request reprint Social support and quality of life in patients with coronary artery disease
    H B Bosworth
    Health Services Research and Development, Durham VAMC, NC 27705, USA
    Qual Life Res 9:829-39. 2000
    ..These individuals may subsequently require the greatest degree of care and potentially benefit most from intervention...
  41. ncbi request reprint The association between self-rated health and mortality in a well-characterized sample of coronary artery disease patients
    H B Bosworth
    Health Services Research and Development, Durham Veterans Affairs Medical Center, North Carolina 27705, USA
    Med Care 37:1226-36. 1999
    ....
  42. ncbi request reprint The relationship between self-rated health and health status among coronary artery patients
    H B Bosworth
    Health Services Research and Development, Durham
    J Aging Health 11:565-84. 1999
    ..This study examined the descriptive relationship of self-rated health (SRH) with various psychosocial measures, sociodemographic variables, coronary artery disease (CAD) diagnostic/clinical measures, and medically abstracted comorbidities...
  43. ncbi request reprint Costs for heart failure with normal vs reduced ejection fraction
    Lawrence Liao
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    Arch Intern Med 166:112-8. 2006
    ..However, there are few data regarding the costs of HF with normal EF. In a prospective, population-based cohort of elderly participants, we compared the costs and resource use of patients with HF and normal and reduced EF...
  44. ncbi request reprint Central nervous system injury associated with cardiac surgery
    Mark F Newman
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 277110, USA
    Lancet 368:694-703. 2006
    ..We describe these issues and the controversies that merit continued investigation...
  45. ncbi request reprint Preventing tomorrow's sudden cardiac death today: part II: Translating sudden cardiac death risk assessment strategies into practice and policy
    Gillian D Sanders
    Duke Clinical Research Institute, Duke Medical Center, Durham, NC 27715, USA
    Am Heart J 153:951-9. 2007
    ....
  46. ncbi request reprint Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation
    Eric L Eisenstein
    Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    JAMA 297:159-68. 2007
    ..Recent studies of drug-eluting intracoronary stents suggest that current antiplatelet regimens may not be sufficient to prevent late stent thrombosis...
  47. ncbi request reprint Facets of openness predict mortality in patients with cardiac disease
    Charles R Jonassaint
    Department of Psychiatry, Duke University, Durham, North Carolina, USA
    Psychosom Med 69:319-22. 2007
    ..To examine the NEO Personality Inventory (NEO PI) Openness to Experience (O) domain and its facets as predictors of cardiac deaths and all-cause mortality...
  48. ncbi request reprint Long-term costs and resource use in elderly participants with congestive heart failure in the Cardiovascular Health Study
    Lawrence Liao
    Duke Clinical Research Institute, Durham, NC, USA
    Am Heart J 153:245-52. 2007
    ..In a prospective, longitudinal cohort of community-dwelling elderly from 4 regions, we examined the long-term costs and resource use of elderly patients with HF...
  49. ncbi request reprint Is early too early? Effect of shorter stays after bypass surgery
    Patricia A Cowper
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
    Ann Thorac Surg 83:100-7. 2007
    ..This study examined the effect of early discharge after CABG on readmission/death and cost within 60 days of discharge home. Variability in hospitals' tendencies for early discharge and adverse outcomes was also explored...
  50. ncbi request reprint Trends in postoperative length of stay after bypass surgery
    Patricia A Cowper
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 152:1194-200. 2006
    ..This study examined trends in postoperative LOS, associated rates of transfer at discharge and variation among hospitals in LOS at CABG hospitals in New York State...
  51. ncbi request reprint Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery
    Barbara Phillips-Bute
    Department of Anesthesiology, Box 3094, DUMC, Duke University Medical Center, Durham, North Carolina 27710, USA
    Psychosom Med 68:369-75. 2006
    ..We sought to determine the impact of this postoperative cognitive dysfunction on quality of life (QOL) and to characterize the dysfunction from the patient's perspective...
  52. pmc The rationale and design of the Surgical Treatment for Ischemic Heart Failure (STICH) trial
    Eric J Velazquez
    Division of Cardiovascular Medicine, Department of Medicine, Duke University Medical Center, Durham, NC Duke Clinical Research Institute, Durham, NC, USA
    J Thorac Cardiovasc Surg 134:1540-7. 2007
    ..Trial data reflect how these therapies were delivered more than 20 years ago and do not indicate the relative benefits of medical therapy versus coronary artery bypass grafting in contemporary practice...
  53. doi request reprint Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery
    Elliott Bennett-Guerrero
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    N Engl J Med 363:1038-49. 2010
    ..The gentamicin-collagen sponge, an implantable topical antibiotic agent, is approved for surgical implantation in 54 countries. Since 1985, more than 1 million patients have been treated with the sponges...
  54. doi request reprint Representation of women in randomized clinical trials of cardiovascular disease prevention
    Chiara Melloni
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Circ Cardiovasc Qual Outcomes 3:135-42. 2010
    ....
  55. doi request reprint Planning the Safety of Atrial Fibrillation Ablation Registry Initiative (SAFARI) as a Collaborative Pan-Stakeholder Critical Path Registry Model: a Cardiac Safety Research Consortium "Incubator" Think Tank
    Sana M Al-Khatib
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Am Heart J 159:17-24. 2010
    ..The meeting took place on April 27 to 28, 2009, at the US Food and Drug Administration headquarters in Silver Spring, MD. This article summarizes the issues and directions presented and discussed at the meeting...
  56. pmc Assessing the economic attractiveness of coronary artery revascularization in chronic kidney disease patients
    Eric L Eisenstein
    Duke University Medical Center, Durham, NC 27715, USA
    J Med Syst 33:287-97. 2009
    ..Medical therapy was an economically attractive strategy vs. CABG surgery or PCI for three-vessel CAD patients with CKD, two-vessel CAD patients without CKD, and all single-vessel CAD patients...
  57. pmc Prospective study of associations among positive emotion and functional status in older patients with coronary artery disease
    Beverly H Brummett
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 2969, Durham, NC 27710, USA
    J Gerontol B Psychol Sci Soc Sci 64:461-9. 2009
    ..Lower levels of PE during follow-up were also related to increasing decline in function but only in men. Thus, our findings indicate that PE is associated with less decline in functional status following hospitalization for CAD...
  58. doi request reprint Effect of an implantable gentamicin-collagen sponge on sternal wound infections following cardiac surgery: a randomized trial
    Elliott Bennett-Guerrero
    Division of Perioperative Clinical Research, Duke Clinical Research Institute, Duke University Medical Center, PO Box 3094, Durham, NC 27710, USA
    JAMA 304:755-62. 2010
    ..A large, 2-center, randomized trial in Sweden reported in 2005 that the sponge reduced surgical site infection by 50% in cardiac patients...
  59. doi request reprint Do income level and race influence survival in patients receiving hemodialysis?
    Eric L Eisenstein
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am J Med 122:170-80. 2009
    ..We sought to determine whether these differences persist and whether the effect of income-area on mortality is different for African Americans versus patients of other races...
  60. doi request reprint Empirical estimation of life expectancy from large clinical trials: use of left-truncated, right-censored survival analysis methodology
    Charlotte L Nelson
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Stat Med 27:5525-55. 2008
    ..The proposed methodology is developed, applied, and evaluated in both a large clinical trial cohort with 5-year follow-up on over 23,000 patients and a large observational database with long-term follow-up on over 4000 patients...
  61. ncbi request reprint The primary and secondary prevention of coronary artery disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    Richard C Becker
    Duke Cardiovascular Thrombosis Center, Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC 27705, USA
    Chest 133:776S-814S. 2008
    ..For primary prevention in patients with moderate risk for a coronary event, we recommend aspirin, 75-100 mg/d, over either no antithrombotic therapy or vitamin K antagonist (Grade 1A)...
  62. ncbi request reprint Strategies for incorporating resource allocation and economic considerations: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    David B Matchar
    Center for Clinical Health Policy, First Union Tower, 2200 W Main Street, Durham, NC 27705, USA
    Chest 133:132S-140S. 2008
    ....
  63. ncbi request reprint Re-evaluating the volume-outcome relationship in hemodialysis patients
    Eric L Eisenstein
    Duke Clinical Research Institute, 2400 Pratt Street, Room 0311, Durham, NC 27705, USA
    Health Policy 88:317-25. 2008
    ..We sought to determine whether dialysis patient mortality rates are associated with differences in dialysis facility size, and whether this relationship differs among higher risk diabetic and lower-risk non-diabetic patients...
  64. doi request reprint Long-term clinical outcomes following coronary stenting
    Kevin J Anstrom
    Department of Biostatistics, Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Intern Med 168:1647-55. 2008
    ..The objective of this study was to compare the long-term clinical outcomes of patients receiving DES vs BMS in a clinical practice setting...
  65. doi request reprint Implantable cardioverter defibrillator therapy in patients with prior coronary revascularization in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    Sana M Al-Khatib
    Duke Clinical Research Institute, Durham, North Carolina 27705, USA
    J Cardiovasc Electrophysiol 19:1059-65. 2008
    ....
  66. doi request reprint Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes
    Sunil V Rao
    The Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 155:369-74. 2008
    ..We sought to determine the relationship between bleeding, blood transfusion, and measures of costs among patients with non-ST-segment elevation ACS...
  67. pmc Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury
    David L McDonagh
    Department of Anesthesiology and Medicine, Division of Cardiothoracic Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 112:852-9. 2010
    ..Identified risk factors are largely limited to demographic characteristics. We hypothesized that POCD was associated with apolipoprotein E4 (APOE4) genotype and plasma biomarkers of brain injury and inflammation...
  68. ncbi request reprint A new anatomic score for prognosis after cardiac catheterization in patients with previous bypass surgery
    Lawrence Liao
    Duke Clinical Research Institute, USA
    J Am Coll Cardiol 46:1684-92. 2005
    ..The purpose of this study was to determine the value of a new anatomic score for prognosis after diagnostic catheterization in patients with previous coronary artery bypass grafting (CABG)...
  69. ncbi request reprint Hostility as a predictor of survival in patients with coronary artery disease
    Stephen H Boyle
    Department of Psychiatry, Duke University Medical Center, Box 2969, Durham, NC, USA
    Psychosom Med 66:629-32. 2004
    ..This study examined the ability of the total CMHS and an abbreviated form of the CMHS (ACM) to predict survival in a sample of patients with documented coronary artery disease (CAD) with increased statistical power...
  70. ncbi request reprint Depression as a risk factor for mortality after coronary artery bypass surgery
    James A Blumenthal
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Lancet 362:604-9. 2003
    ..We sought to assess whether depression is associated with an increased risk of mortality...
  71. ncbi request reprint Effect of smoking and sedentary behavior on the association between depressive symptoms and mortality from coronary heart disease
    Beverly H Brummett
    Department of Psychiatry and Behavioral Sciences, Durham, North Carolina 27710, USA
    Am J Cardiol 92:529-32. 2003
    ..Results indicated that smoking and/or sedentary behavior may partially mediate the relation between depressive symptoms and mortality. No evidence for moderation was found...
  72. ncbi request reprint Chronic kidney disease, mortality, and treatment strategies among patients with clinically significant coronary artery disease
    Donal N Reddan
    Duke Institute for Renal Outcomes Research and Health Policy, Division of Nephrology, Duke Clinical Research Institute, Duke University Medical Center, Duke University Medical Center, Durham, North Carolina, USA
    J Am Soc Nephrol 14:2373-80. 2003
    ..Among patients with severe CKD, PCI was not associated with improved survival. CABG is associated with greater mortality reduction than PCI in severe CKD...
  73. pmc Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery
    Joseph P Mathew
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Stroke 40:880-7. 2009
    ..Based on experimental and clinical evidence, this study assessed the potential of intravenously administered lidocaine to reduce postoperative cognitive dysfunction after cardiac surgery using cardiopulmonary bypass...
  74. ncbi request reprint Poverty, process of care, and outcome in acute coronary syndromes
    Sunil V Rao
    Duke Clinical Research Institute, dDuke University, PO Box 17969, Durham, NC 27715, USA
    J Am Coll Cardiol 41:1948-54. 2003
    ..We sought to determine whether income-based disparities in care processes and outcome exist in patients with acute coronary syndromes...
  75. ncbi request reprint A national survey of provisions in clinical-trial agreements between medical schools and industry sponsors
    Kevin A Schulman
    Center for Clinical and Genetic Economics, Duke University Medical Center, Durham, NC, USA
    N Engl J Med 347:1335-41. 2002
    ..It is unclear whether research conducted at academic institutions adheres to these new standards...
  76. ncbi request reprint Perceived social support as a predictor of mortality in coronary patients: effects of smoking, sedentary behavior, and depressive symptoms
    Beverly H Brummett
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 2969, Durham, NC 27710, USA
    Psychosom Med 67:40-5. 2005
    ....
  77. ncbi request reprint Ratings of positive and depressive emotion as predictors of mortality in coronary patients
    Beverly H Brummett
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    Int J Cardiol 100:213-6. 2005
    ..An extensive body of research has demonstrated an association between negative affective states and health outcomes. Positive emotions may also influence physical health, however, their examination has received far less attention...
  78. ncbi request reprint Obesity and long-term clinical and economic outcomes in coronary artery disease patients
    Eric L Eisenstein
    The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    Obes Res 10:83-91. 2002
    ..We assessed the impact of increasing body mass index (BMI) on 10-year outcomes for ACS patients...
  79. ncbi request reprint Vasopeptidase inhibitor reduces inhospital costs for patients with congestive heart failure: results from the IMPRESS trial. Inhibition of Metallo Protease by BMS-186716 in a Randomized Exercise and Symptoms Study in Subjects With Heart Failure
    Eric L Eisenstein
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 143:1112-7. 2002
    ..They also had significantly fewer serious cardiac adverse events...
  80. ncbi request reprint Hostility, age, and mortality in a sample of cardiac patients
    Stephen H Boyle
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 96:64-6. 2005
    ..After controlling for disease severity, there was a significant interaction between age and hostility. Hostility was significantly associated with poorer survival but only in younger (<61.2 years) patients...
  81. ncbi request reprint Implantable cardioverter defibrillators and cardiac resynchronization therapy in patients with left ventricular dysfunction: randomized trial evidence through 2004
    Sana M Al-Khatib
    The Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 149:1020-34. 2005
    ..This document summarizes the evidence reviewed at that meeting and the discussions of that evidence...
  82. ncbi request reprint Surgeons' economic profiles: can we get the "right" answers?
    Eric L Eisenstein
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, 27715 7969, USA
    J Med Syst 29:111-24. 2005
    ..Adjusting for patient-mix differences and treating surgeons as random effects was the preferred approach. These results demonstrate the need for hospitals to reexamine their economic profiling methods...
  83. ncbi request reprint Variability in cost of coronary bypass surgery in New York State: potential for cost savings
    Patricia A Cowper
    Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 143:130-9. 2002
    ....
  84. ncbi request reprint Conducting economic evaluations alongside multinational clinical trials: toward a research consensus
    Shelby D Reed
    Center for Clinical and Genetic Economics, Duke University Medical Centre, Durham, NC, USA
    Am Heart J 149:434-43. 2005
    ..Delineation of the various approaches to multinational economic evaluation may assist researchers, peer reviewers, journal editors, and decision makers in evaluating the strengths and limitations of particular studies...
  85. ncbi request reprint Economic impact of drug-eluting stents on hospital systems: a disease-state model
    David F Kong
    Duke Clinical Research Institute, DUMC, Durham, NC 27710, USA
    Am Heart J 147:449-56. 2004
    ..The US Department of Health and Human Services (HHS), recognizing the financial and clinical impact of this technology, recently proposed accelerated reimbursement to hospitals...
  86. ncbi request reprint Mortality benefits from implantable cardioverter-defibrillator therapy are not restricted to patients with remote myocardial infarction: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    Jonathan P Piccini
    Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Heart Rhythm 8:393-400. 2011
    ....
  87. ncbi request reprint Characteristics of socially isolated patients with coronary artery disease who are at elevated risk for mortality
    B H Brummett
    Behavioral Medicine Research Center, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
    Psychosom Med 63:267-72. 2001
    ..Social isolation has been linked to poor survival in patients with coronary artery disease (CAD). Few studies have closely examined the psychosocial characteristics of CAD patients who lack social contact...
  88. ncbi request reprint Impact of an interactive video on decision making of patients with ischemic heart disease
    L Liao
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Gen Intern Med 11:373-6. 1996
    ..0001). The greatest effects appeared to be concentrated in those patients with less education (p = .04), and the program appeared to increase anxiety in nonwhite patients compared with white patients (p = 0.07)...
  89. ncbi request reprint Time-based risk assessment after myocardial infarction. Implications for timing of discharge and applications to medical decision-making
    L K Newby
    The Duke Clinical Research Institute, Durham, NC 27715 7969, USA
    Eur Heart J 24:182-9. 2003
    ..We evaluated timing of adverse cardiac events after thrombolysis to guide length of stay after ST-segment elevation myocardial infarction...
  90. ncbi request reprint The value of estimated functional capacity in estimating outcome: results from the NHBLI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Am Coll Cardiol 47:S36-43. 2006
    ..Our objective was to determine the prognostic value of estimated metabolic equivalents (METs) based on self-reported functional capacity by the Duke Activity Status Index (DASI) in symptomatic women...
  91. ncbi request reprint Risk stratification in patients with chest pain
    D B Mark
    Duke University Medical Center, Outcomes Research and Assessment Group, Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC 27715, USA
    Prim Care 28:99-118 ,vii. 2001
    ..This review focuses on the standard treadmill exercise test...
  92. ncbi request reprint Prospective randomized trial of normothermic versus hypothermic cardiopulmonary bypass on cognitive function after coronary artery bypass graft surgery
    A M Grigore
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 95:1110-9. 2001
    ..CONCLUSIONS: Hypothermic CPB does not provide additional central nervous system protection in adult cardiac surgical patients who were maintained at either 30 or 35 degrees C during CPB...
  93. ncbi request reprint Impact of different patterns of invasive care on quality of life outcomes in patients with non-ST elevation acute coronary syndrome: results from the GUSTO-IIb Canada-United States substudy
    Padma Kaul
    University of Alberta, Edmonton
    Can J Cardiol 20:760-6. 2004
    ....
  94. ncbi request reprint Design and methodology of the Occluded Artery Trial (OAT)
    Judith S Hochman
    Am Heart J 150:627-42. 2005
    ..If not, this strategy should be avoided in this large subgroup of post-MI patients...
  95. ncbi request reprint Glycoprotein IIb-IIIa inhibition with abciximab and postprocedural risk assessment: lessons from the evaluation of platelet IIb/IIIa inhibitor for stenting trial and implication for ad hoc use of glycoprotein IIb-IIIa antagonists
    Wojciech Mazur
    Baylor College of Medicine and The Methodist Hospital, Houston, Tex, USA
    Am Heart J 143:594-601. 2002
    ..The purpose of this study was to compare the effects of abciximab in patients with and without high-risk postprocedure features...
  96. ncbi request reprint Conservative management of acute coronary syndrome: cheaper and better for you?
    Daniel B Mark
    Circulation 105:666-8. 2002
  97. ncbi request reprint Fixing the heart: must the brain pay the price?
    Mark F Newman
    Circulation 110:3402-3. 2004
  98. ncbi request reprint Clinical prediction models: are we building better mousetraps?
    Lawrence Liao
    J Am Coll Cardiol 42:851-3. 2003
  99. pmc Coronary intervention for persistent occlusion after myocardial infarction
    Judith S Hochman
    Cardiovascular Clinical Research Center, Leon Charney Division of Cardiology, New York University School of Medicine, New York 10016, USA
    N Engl J Med 355:2395-407. 2006
    ....
  100. ncbi request reprint ACC/AHA 2002 guideline update for exercise testing: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines)
    Raymond J Gibbons
    J Am Coll Cardiol 40:1531-40. 2002
  101. ncbi request reprint Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure
    Gust H Bardy
    Seattle Institute for Cardiac Research, Seattle, WA 98103, USA
    N Engl J Med 352:225-37. 2005
    ..Treatment with amiodarone or an implantable cardioverter-defibrillator (ICD) has been proposed to improve the prognosis in such patients...