Dagan A Loisel
Affiliation: Duke University Medical Center
- Ancient polymorphism and functional variation in the primate MHC-DQA1 5' cis-regulatory regionDagan A Loisel
Department of Biology, Duke University, Durham, NC 27705, USA
Proc Natl Acad Sci U S A 103:16331-6. 2006....
- Positive selection on MMP3 regulation has shaped heart disease riskMatthew V Rockman
Department of Biology, Duke University, Box 90338, Durham, NC 27708, USA
Curr Biol 14:1531-9. 2004..The polymorphism contributes to variation in arterial traits and to the risk of coronary heart disease and its progression...
- Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effectsKarlyne M Reilly
Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD 21702, USA
Proc Natl Acad Sci U S A 101:13008-13. 2004..Because analysis of gene function in the mouse is often performed on a mixed C57BL/6,129 strain background, these data also provide a powerful example of the potential of these strains to mask interesting gene functions...
- An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse modelKarlyne M Reilly
Mouse Cancer Genetics Program, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA
Cancer Res 66:62-8. 2006..This interaction of an imprinted locus and polymorphic susceptibility loci has profound implications for human mapping studies where the parental contribution of alleles is often unknown...