Tong Liu

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?
    Tong Liu
    Pain Signaling and Plasticity Laboratory, Department of Anesthesiology and Neurobiology, Duke University Medical Center, 595 LaSalle Street, GSRB I, Room 1027A, DUMC 3094, Durham, NC, 27710, USA
    Pflugers Arch 465:1671-85. 2013
  2. ncbi request reprint A Monoclonal Antibody that Targets a NaV1.7 Channel Voltage Sensor for Pain and Itch Relief
    Jun Ho Lee
    Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA
    Cell 157:1393-404. 2014
  3. pmc Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels
    Promila Pagadala
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 33:13425-30. 2013

Collaborators

  • Ru Rong Ji
  • Gang Chen
  • Jun Ho Lee
  • Rou Gang Xie
  • Chul Kyu Park
  • Promila Pagadala
  • Qingjian Han
  • Seok Yong Lee
  • Sangsu Bang
  • Fan Wang
  • Bao Xia Han
  • W Daniel Tracey
  • Zheng zhong Xu

Detail Information

Publications3

  1. pmc New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?
    Tong Liu
    Pain Signaling and Plasticity Laboratory, Department of Anesthesiology and Neurobiology, Duke University Medical Center, 595 LaSalle Street, GSRB I, Room 1027A, DUMC 3094, Durham, NC, 27710, USA
    Pflugers Arch 465:1671-85. 2013
    ..g., atopic dermatitis), and some drugs for treating chronic pain are also effective in chronic itch. Thus, itch and pain have more similarities in pathological and chronic conditions. ..
  2. ncbi request reprint A Monoclonal Antibody that Targets a NaV1.7 Channel Voltage Sensor for Pain and Itch Relief
    Jun Ho Lee
    Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA
    Cell 157:1393-404. 2014
    ..Our studies reveal that NaV1.7 is a target for itch management, and the antibody has therapeutic potential for suppressing pain and itch. Our antibody strategy may have broad applications for voltage-gated cation channels. ..
  3. pmc Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels
    Promila Pagadala
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosci 33:13425-30. 2013
    ..Our results also call attention to potential opposing effects of NMDAR antagonists as a treatment for pain and other neurological disorders. ..