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8 bromo cyclic adenosine monophosphate
cyclic gmp dependent protein kinases
Duke University Medical Center
Liu L, Simon S. Modulation of IA currents by capsaicin in rat trigeminal ganglion neurons. J Neurophysiol. 2003;89:1387-401
..That activation, partially through the activation of cGMP-PKG and calmodulin-dependent pathways should result in increased excitability of capsaicin-sensitive nociceptors. ..
Liu L, Yang T, Bruno M, Andersen O, Simon S. Voltage-gated ion channels in nociceptors: modulation by cGMP. J Neurophysiol. 2004;92:2323-32
..This pathway may be a target for efforts to produce selective analgesics. ..
Experts and Doctors on capsaicin in Durham, North Carolina, United States
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