Walter T Lee

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Utility of Intraoperative Frozen Sections during Thyroid Surgery
    Russel Kahmke
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Duke University Medical Center, Duke University, Durham, NC 27710, USA
    Int J Otolaryngol 2013:496138. 2013
  2. pmc Surgical Training and Education in Promoting Professionalism: a comparative assessment of virtue-based leadership development in otolaryngology-head and neck surgery residents
    Kristine Schulz
    Division of Otolaryngology, Head and Neck Surgery, Duke University Medical Center, Durham, NC, USA
    Med Educ Online 18:22440. 2013
  3. ncbi request reprint Dendritic cell vaccines targeting survivin in head and neck cancer
    Walter T Lee
    Section of Otolaryngology, Head and Neck Surgery, Veteran Affairs Medical Center, Durham, NC 27705, USA and Division of Otolaryngology, Head and Neck Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Immunotherapy 5:1169-71. 2013
  4. doi request reprint Treatment-induced changes in vocal cord mobility and subsequent local recurrence after organ preservation therapy for laryngeal carcinoma
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Head Neck 34:792-6. 2012
  5. ncbi request reprint Immunotherapy using allogeneic squamous cell tumor-dendritic cell fusion hybrids
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Head Neck 32:1209-16. 2010
  6. doi request reprint Impact of preepiglottic space tumor involvement on concurrent chemoradiation therapy
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Am J Otolaryngol 31:185-8. 2010
  7. doi request reprint Dendritic cell-tumor cell fusion vaccines
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Adv Exp Med Biol 713:177-86. 2011
  8. doi request reprint Use of in situ hybridization to detect human papillomavirus in head and neck squamous cell carcinoma patients without a history of alcohol or tobacco use
    Walter T Lee
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Arch Pathol Lab Med 132:1653-6. 2008
  9. ncbi request reprint Ansa cervicalis-to-recurrent laryngeal nerve anastomosis for unilateral vocal fold paralysis: experience of a single institution
    Robert R Lorenz
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Ann Otol Rhinol Laryngol 117:40-5. 2008
  10. doi request reprint Local secretion of IL-12 augments the therapeutic impact of dendritic cell-tumor cell fusion vaccination
    Chunrui Tan
    Division of Otolaryngology, Duke University Medical Center, Durham, North Carolina
    J Surg Res 185:904-11. 2013

Collaborators

Detail Information

Publications41

  1. pmc Utility of Intraoperative Frozen Sections during Thyroid Surgery
    Russel Kahmke
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Duke University Medical Center, Duke University, Durham, NC 27710, USA
    Int J Otolaryngol 2013:496138. 2013
    ....
  2. pmc Surgical Training and Education in Promoting Professionalism: a comparative assessment of virtue-based leadership development in otolaryngology-head and neck surgery residents
    Kristine Schulz
    Division of Otolaryngology, Head and Neck Surgery, Duke University Medical Center, Durham, NC, USA
    Med Educ Online 18:22440. 2013
    ..The purpose of this research was: (i) to compare the virtue profiles of our residents with that of the military cohort using a standardized virtue assessment tool; and (ii) to assess the value of virtue education on residents...
  3. ncbi request reprint Dendritic cell vaccines targeting survivin in head and neck cancer
    Walter T Lee
    Section of Otolaryngology, Head and Neck Surgery, Veteran Affairs Medical Center, Durham, NC 27705, USA and Division of Otolaryngology, Head and Neck Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Immunotherapy 5:1169-71. 2013
    ..The evaluated paper therefore concluded that strategies that rely on expansion and adoptive transfer of survivin-specific T cells would not be possible...
  4. doi request reprint Treatment-induced changes in vocal cord mobility and subsequent local recurrence after organ preservation therapy for laryngeal carcinoma
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Head Neck 34:792-6. 2012
    ..As multidisciplinary cancer treatment evolves, strategies to identify patients needing early resection/salvage are necessary. Some have suggested that vocal cord function after organ-preservation treatment may be an indicator...
  5. ncbi request reprint Immunotherapy using allogeneic squamous cell tumor-dendritic cell fusion hybrids
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Head Neck 32:1209-16. 2010
    ..Tumor-associated antigens (TAAs) are known to be immunotherapy targets; thus tumor-sharing TAA may be used as a fusion hybrid partner to confer protection against subsequent tumor challenge...
  6. doi request reprint Impact of preepiglottic space tumor involvement on concurrent chemoradiation therapy
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Am J Otolaryngol 31:185-8. 2010
    ..The aim of the study was to determine the prognostic impact of preepiglottic space (PES) involvement on local failure after concurrent chemoradiation therapy for squamous cell carcinoma...
  7. doi request reprint Dendritic cell-tumor cell fusion vaccines
    Walter T Lee
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Adv Exp Med Biol 713:177-86. 2011
    ..This will include basic principles of tumor fusion vaccines, summary of pre-clinical and clinical data, concluding with remaining challenges and directions...
  8. doi request reprint Use of in situ hybridization to detect human papillomavirus in head and neck squamous cell carcinoma patients without a history of alcohol or tobacco use
    Walter T Lee
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Arch Pathol Lab Med 132:1653-6. 2008
    ..There are, however, a group of patients without a significant history of tobacco or alcohol use, and the etiology of these tumors is incompletely understood...
  9. ncbi request reprint Ansa cervicalis-to-recurrent laryngeal nerve anastomosis for unilateral vocal fold paralysis: experience of a single institution
    Robert R Lorenz
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Ann Otol Rhinol Laryngol 117:40-5. 2008
    ..We present all patients who have undergone ansa-RLN anastomosis for UVFP at our institution...
  10. doi request reprint Local secretion of IL-12 augments the therapeutic impact of dendritic cell-tumor cell fusion vaccination
    Chunrui Tan
    Division of Otolaryngology, Duke University Medical Center, Durham, North Carolina
    J Surg Res 185:904-11. 2013
    ..To overcome this limitation, we developed a novel approach in which DC-tumor fusion cells locally secrete IL-12, then evaluated the effectiveness of this approach in a murine B16 melanoma model...
  11. ncbi request reprint Toll-like receptor agonists as third signals for dendritic cell-tumor fusion vaccines
    Edward I Cho
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Head Neck 32:700-7. 2010
    ..The aim of the present study was to evaluate the therapeutic efficacy of dendritic cell (DC)-tumor fusion hybrids with Toll-like receptor (TLR) agonists...
  12. ncbi request reprint Immunogenicity of dendritic-tumor fusion hybrids and their utility in cancer immunotherapy
    Suyu Shu
    Center for Surgery Research, NE6 307, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Crit Rev Immunol 27:463-83. 2007
    ....
  13. ncbi request reprint Immunotherapy of established murine squamous cell carcinoma using fused dendritic-tumor cell hybrids
    Walter T Lee
    Center for Surgery Research and Head and Neck Institute, Cleveland Clinic, Cleveland Ohio 44195, USA
    Arch Otolaryngol Head Neck Surg 134:608-13. 2008
    ..To investigate the therapeutic efficacy of fused dendritic-tumor cell hybrids against murine squamous cell carcinoma (SCC)...
  14. ncbi request reprint Laryngeal transplantation in the setting of cancer: a rat model
    Taha Z Shipchandler
    Head and Neck Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Laryngoscope 118:2166-71. 2008
    ..The purpose of this study was to examine the effects of everolimus alone and in combination with other immunosuppressants on tumor growth in a combined laryngeal transplantation and tumor model...
  15. ncbi request reprint Effect of physician perspective on allocation of medicare resources for patients with advanced cancer
    Daniel J Rocke
    Department of Surgery, Division of Otolaryngology, Head and Neck Surgery OHNS, Duke University Medical Center, Durham, North Carolina, USA
    Otolaryngol Head Neck Surg 150:792-800. 2014
    ....
  16. pmc Assessment of the sensitivity and specificity of tissue-specific-based and anatomical-based optical biomarkers for rapid detection of human head and neck squamous cell carcinoma
    Fangyao Hu
    Duke University, Biomedical Engineering Department, Durham, NC, USA
    Oral Oncol 50:848-56. 2014
    ..We propose the use of morphological optical biomarkers for rapid detection of human head and neck squamous cell carcinoma (HNSCC) by leveraging the underlying tissue characteristics in aerodigestive tracts...
  17. pmc Impact of anti-CD25 monoclonal antibody on dendritic cell-tumor fusion vaccine efficacy in a murine melanoma model
    Chunrui Tan
    Division of Otolaryngology, Duke University Medical Center, Durham, NC, USA
    J Transl Med 11:148. 2013
    ....
  18. ncbi request reprint Effectiveness of a postoperative disposition protocol for sleep apnea surgery
    Daniel Rocke
    Department of Surgery, Division of Otolaryngology, Head and Neck Surgery, USA
    Am J Otolaryngol 34:273-7. 2013
    ..2) Compare the cost-effectiveness of outpatient and overnight observational sleep apnea surgery versus surgical intensive care admission determined by preoperative screening criteria...
  19. doi request reprint Regional spread of cutaneous squamous cell carcinoma of the face via facial vein tumor thrombus: a case report
    Aysenur Meric Teker
    Cleveland Clinic Head and Neck Institute, Cleveland, OH 44195, USA
    Am J Otolaryngol 29:423-5. 2008
    ....
  20. ncbi request reprint Risk factors for hypopharyngeal/upper esophageal stricture formation after concurrent chemoradiation
    Walter T Lee
    Head and Neck Institute, Cleveland Clinic Foundation, Ohio Desk A71, 9500 Euclid Ave, Cleveland, Ohio 44195, USA
    Head Neck 28:808-12. 2006
    ..One side effect is the formation of upper esophageal strictures. As concurrent chemoradiation treatment is used more frequently, it is important to identify risk factors associated with stricture formation...
  21. ncbi request reprint Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy
    Rongxiu Zheng
    Center for Surgery Research, Cleveland Clinic, Cleveland, Ohio, USA
    Cancer Treat Res 135:223-37. 2007
  22. ncbi request reprint Patient reported outcomes in endoscopic and open transcervical treatment for Zenker's diverticulum
    Rahul Seth
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio
    Laryngoscope 124:119-25. 2014
    ..To compare long-term symptomatic outcomes between external transcervical (ET) and endoscopic stapling diverticulotomy (ESD) surgeries for Zenker's diverticulum...
  23. ncbi request reprint Tumor-dendritic cell fusion as a basis for cancer immunotherapy
    Walter T Lee
    Head and Neck Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Otolaryngol Head Neck Surg 132:755-64. 2005
    ..To establish the basis for use of allogeneic dendritic-tumor fusion cells...
  24. pmc Paired Toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12
    Rongxiu Zheng
    Center for Surgery Research, Department of Immunology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Cancer Res 68:4045-9. 2008
    ..These results show the profound functional consequences of TLR cooperativity and further highlight the critical role of IL-12 in antitumor immunity...
  25. ncbi request reprint Radiology quiz case 1. Tracheocele
    Aysenur Meric Teker
    Cleveland Clinic, Cleveland, OH, USA
    Arch Otolaryngol Head Neck Surg 133:940, 942-3. 2007
  26. doi request reprint Physician knowledge of and attitudes toward the Patient Protection and Affordable Care Act
    Daniel J Rocke
    Department of Surgery, Division of Otolaryngology, Head and Neck Surgery OHNS, Duke University Medical Center, Durham, North Carolina, USA
    Otolaryngol Head Neck Surg 150:229-34. 2014
    ..To assess otolaryngology physician knowledge of and attitudes toward the Patient Protection and Affordable Care Act (PPACA) and compare the association of bias toward the PPACA with knowledge of the provisions of the PPACA...
  27. doi request reprint Physician allocation of Medicare resources for patients with advanced cancer
    Daniel J Rocke
    Department of Surgery, Division of Otolaryngology, Head, and Neck Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Palliat Med 16:857-66. 2013
    ..Little is known about what patients and physicians value in end-of-life care, or how these groups would craft a health plan for those with advanced cancer...
  28. doi request reprint Qualities of residency applicants: comparison of otolaryngology program criteria with applicant expectations
    Liana Puscas
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Arch Otolaryngol Head Neck Surg 138:10-4. 2012
    ..To evaluate the criteria used by otolaryngology programs in ranking residency candidates and to compare residency candidate ranking criteria among otolaryngology programs and applicant expectations...
  29. ncbi request reprint Obstructing pyogenic granuloma as a result of blunt laryngeal trauma
    Matthew M Garrett
    Case Western Reserve University School of Medicine, Cleveland Clinic, Cleveland, OH 44118, USA
    Otolaryngol Head Neck Surg 136:489-90. 2007
  30. pmc Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function
    Jens Dannull
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Blood 119:3113-22. 2012
    ..Collectively, our data suggest that LTC(4) represents a promising candidate to replace PGE(2) in DC maturation protocols for cancer vaccination...
  31. ncbi request reprint Results of ansa to recurrent laryngeal nerve reinnervation
    Walter T Lee
    Department of Otolaryngology, Head and Neck Surgery, Cleveland Clinic, Cleveland, OH 44195, USA
    Otolaryngol Head Neck Surg 136:450-4. 2007
    ..We sought to describe the results of ansa cervicalis to recurrent laryngeal nerve (ansa-RLN) reinnervation for unilateral vocal fold paralysis...
  32. doi request reprint Comparison of applicant criteria and program expectations for choosing residency programs in the otolaryngology match
    Scott Sharp
    Division of Otolaryngology Head and Neck Surgery, Duke University, Durham, North Carolina 27710, USA
    Otolaryngol Head Neck Surg 144:174-9. 2011
    ..To evaluate criteria used by residency applicants in ranking otolaryngology residency programs and to compare applicant criteria with program expectations of ranking otolaryngology residency programs...
  33. pmc Rapid determination of oxygen saturation and vascularity for cancer detection
    Fangyao Hu
    Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America
    PLoS ONE 8:e82977. 2013
    ..In addition, the discriminatory power of the two analyses was similar. These results show the potential of such empirical tools to rapidly estimate tissue hemoglobin in real-time spectral imaging applications. ..
  34. doi request reprint Sentinel node biopsy for head and neck melanoma: a systematic review
    Nicole de Rosa
    Duke University, Durham, NC, USA
    Otolaryngol Head Neck Surg 145:375-82. 2011
    ..This systematic review was conducted to examine the test performance of sentinel node biopsy in head and neck melanoma, including the identification rate and false-negative rate...
  35. ncbi request reprint Evaluation of endoscopic harmonic diverticulostomy
    Chad Whited
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Duke University Hospital, Durham, North Carolina 27707, USA
    Laryngoscope 122:1297-300. 2012
    ....
  36. pmc Detection of squamous cell carcinoma and corresponding biomarkers using optical spectroscopy
    H Wolfgang Beumer
    Division of Otolaryngology Head and Neck Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Otolaryngol Head Neck Surg 144:390-4. 2011
    ..Investigate the use of optical reflectance spectroscopy to differentiate malignant and nonmalignant tissues in head and neck lesions and characterize corresponding oxygen tissue biomarkers that are associated with pathologic diagnosis...
  37. ncbi request reprint First case of laryngeal glomangiomyoma
    Walter T Lee
    Head and Neck Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Laryngoscope 115:2038-40. 2005
    ..We present the first case of a laryngeal glomangiomyoma. Furthermore, this lesion was successfully excised endoscopically with a CO2 laser...
  38. pmc An analysis of registered clinical trials in otolaryngology from 2007 to 2010: ClinicalTrials.gov
    David L Witsell
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA
    Otolaryngol Head Neck Surg 149:692-9. 2013
    ..gov database; compare this otolaryngology cohort of interventional studies to clinical visits in a health care system; and assess agreement between clinical trials and clinical activity...
  39. ncbi request reprint Acute external laryngotracheal trauma: diagnosis and management
    Walter T Lee
    Head and Neck Institute, The Cleveland Clinic, 9500 Euclid Ave, Desk A 71, Cleveland, OH 44195, USA
    Ear Nose Throat J 85:179-84. 2006
    ..Although there is some controversy regarding care, treatment in experienced hands will usually result in a favorable outcome. In this article, we review and update the diagnosis and management of acute external laryngotracheal trauma...
  40. doi request reprint Lateral lamella of the cribriform plate: software-enabled computed tomographic analysis and its clinical relevance in skull base surgery
    C Arturo Solares
    Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Arch Otolaryngol Head Neck Surg 134:285-9. 2008
    ..To describe a quantitative analysis of the lateral lamella of the cribriform plate (LLCP) height in computed tomographic (CT) images. The LLCP is the thinnest anatomic structure in the skull base...
  41. doi request reprint Bilateral renal cell carcinoma metastasis in the oral cavity
    Brian Schwab
    Duke University Medical Center, Durham, NC 27710, USA
    Am J Otolaryngol 33:154-5. 2012
    ..Appropriate follow-up and a high index of suspicion will remain necessary. Surgical excision is the treatment of choice...