Research Topics
Genomes and Genes | Anand S LagooSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Publications
Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas?Anand S Lagoo
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Arch Pathol Lab Med 132:1405-16. 2008..Marginal zone lymphomas (MZLs) are the most common lymphomas encountered in the orbit and ocular adnexa. The accurate categorization of these lymphomas is critical to avoid undertreatment or overtreatment...
Morphologic examination of sequential bone marrow biopsies after nonmyeloablative stem cell transplantation complements molecular studies of donor engraftmentAnand S Lagoo
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Arch Pathol Lab Med 130:1479-88. 2006..Nonmyeloablative stem cell transplantation (NMSCT) is a mode of immunotherapy increasingly employed in treating hematologic, lymphoid, and solid tumors. Patients are monitored principally by molecular analysis of donor engraftment...- The value of fluorescence in situ hybridization and polymerase chain reaction in the diagnosis of B-cell non-Hodgkin lymphoma by fine-needle aspirationAnne M Safley
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Arch Pathol Lab Med 128:1395-403. 2004..By incorporating FISH and PCR methods, FNA may assume an expanded role for the primary diagnosis of B-cell non-Hodgkin lymphoma... - Feasibility of low-dose interleukin-2 therapy following T-cell-depleted nonmyeloablative allogeneic hematopoietic stem cell transplantation from HLA-matched or -mismatched family member donorsDavid A Rizzieri
Department of Medicine, Division of Cellular Therapy, Duke University Medical Center, Durham, North Carolina 27710, USA
Cancer Invest 29:56-61. 2011..The primary objective of this pilot study was to evaluate the feasibility of administering IL-2 following a T-cell-depleted nonmyeloablative hematopoietic stem cell transplant... - Posttransplant lymphoproliferative disorder following nonmyeloablative allogeneic stem cell transplantationMatthew J Snyder
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Am J Surg Pathol 28:794-800. 2004..All three PTLDs arose 6 to 7 months after NMST and were rapidly fatal. The pathology of the PTLD in all cases was donor origin, EBV positive, diffuse large B-cell lymphoma... 
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAsDereje D Jima
Duke Institute for Genome Sciences and Policy, Duke University, Durham, NC, USA
Blood 116:e118-27. 2010..Thus, our work suggests that more than a third of the miRNAs present in most cellular types are currently unknown and that these miRNAs may regulate important cellular functions...- Clinicopathologic findings in high-grade B-cell lymphomas with typical Burkitt morphologic features but lacking the MYC translocationDeborah W Sevilla
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Am J Clin Pathol 128:981-91. 2007..Provisional identification of MYC- lymphomas with typical Burkitt morphologic features as an entity separate from DLBCL will facilitate further studies and possible categorization as a separate entity... - A single tube, four-color flow cytometry assay for evaluation of ZAP-70 and CD38 expression in chronic lymphocytic leukemiaNagwa M Hassanein
Department of Pathology, Box 3712, Duke University Medical Center, Durham, NC 27710, USA
Am J Clin Pathol 133:708-17. 2010..It may be necessary to evaluate several prognostic markers simultaneously in CLL, and availability of convenient assays for ZAP-70 and CD38 is desirable for optimal clinical decision making... - Posttransplant lymphoproliferative disorder after umbilical cord blood transplantation in childrenJerald Z Gong
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Am J Surg Pathol 30:328-36. 2006..PTLD may be of donor or recipient origin depending on engraftment status. Both monomorphic and polymorphic histology may be seen, and monomorphic histology appears to predict an unfavorable prognosis... - A role for E2F activities in determining the fate of Myc-induced lymphomagenesisRachel E Rempel
Duke Institute for Genome Sciences and Policy, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
PLoS Genet 5:e1000640. 2009.... - The genetic landscape of mutations in Burkitt lymphomaCassandra Love
Duke Institute for Genome Sciences and Policy, Duke University, Durham, NC, USA
Nat Genet 44:1321-5. 2012..We show experimentally that ID3 mutations promote cell cycle progression and proliferation. Our work thus elucidates commonly occurring gene-coding mutations in Burkitt lymphoma and implicates ID3 as a new tumor suppressor gene... - Diagnostic impact of core-needle biopsy on fine-needle aspiration of non-Hodgkin lymphomaJerald Z Gong
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
Diagn Cytopathol 31:23-30. 2004..Cases insufficient for diagnosis may be seen in both core-needle biopsy and FNA. A combined approach reduces the number of insufficient cases and is recommended in routine FNA practice... - Patterns of microRNA expression characterize stages of human B-cell differentiationJenny Zhang
Duke Institute for Genome Sciences and Policy, Duke University, Durham, NC 27710, USA
Blood 113:4586-94. 2009..Thus, our data demonstrate that microRNAs may be important in maintaining the mature B-cell phenotype in normal and malignant B cells... - Re-induction therapy decisions based on day 14 bone marrow biopsy in acute myeloid leukemiaTod A Morris
Division of Medical Oncology, Duke University Health System, Durham, NC, USA
Leuk Res 37:28-31. 2013..The aim of our review was to evaluate the accuracy of a day 14 BM biopsy in determining the need for re-induction chemotherapy... - Burkitt lymphoma arising in organ transplant recipients: a clinicopathologic study of five casesJerald Z Gong
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Am J Surg Pathol 27:818-27. 2003..Genotypic and phenotypic aberrations are often present. Rituximab may be an effective alternative to conventional combination chemotherapy in the treatment of a posttransplant Burkitt lymphoma... - Lymphoma of the female genital tract: current statusAnand S Lagoo
Department of Pathology, Duke University Medical Center, Durham, NC 27110, USA
Int J Gynecol Pathol 25:1-21. 2006..Finally, the possible etiology of these conditions is discussed in light of the emerging paradigm of mucosa-associated lymphoid tissue lymphomas... - Distinct expression patterns of CD123 and CD34 on normal bone marrow B-cell precursors ("hematogones") and B lymphoblastic leukemia blastsNagwa M Hassanein
Department of Pathology, Duke University Medical Center, Durham, NC 22170, USA
Am J Clin Pathol 132:573-80. 2009.... - Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphomaSeiichi Mori
Department of Molecular Genetics and Microbiology, Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina 27708, USA
Cancer Res 68:8525-34. 2008..Taken together, these studies provide insight into the complexity of the oncogenic process and a novel strategy for dissecting the heterogeneity of B lymphoma... - SMAD4 is required for development of maximal endotoxin toleranceHongjie Pan
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Immunol 184:5502-9. 2010..We conclude that in THP-1 cells and primary murine cells, SMAD4 signaling is required for maximal induction of endotoxin tolerance via modulation of SHIP1 and IRAK-M... - Nodular lymphocyte predominant Hodgkin lymphoma at atypical locations may be associated with increased numbers of large cells and a diffuse histologic componentDavid T Yang
Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Am J Hematol 83:218-21. 2008..From 55 cases of NLPHL, we describe a possible subset of NLPHL occurring in older individuals at atypical sites, associated with increased numbers of large cells, a diffuse histologic component, and expression of Bcl-2...