Stanislav G Kozmin

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Genetic characterization of moaB mutants of Escherichia coli
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Res Microbiol 164:689-94. 2013
  2. pmc The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells
    Stanislav G Kozmin
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA
    Genetics 193:803-17. 2013
  3. pmc TusA (YhhP) and IscS are required for molybdenum cofactor-dependent base-analog detoxification
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709
    Microbiologyopen 2:743-55. 2013
  4. pmc Role for CysJ flavin reductase in molybdenum cofactor-dependent resistance of Escherichia coli to 6-N-hydroxylaminopurine
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, MD E3 01, National Institute of Environmental Health Sciences, 111 TW Alexander Drive, Research Triangle Park, NC 27709, USA
    J Bacteriol 192:2026-33. 2010
  5. pmc YcbX and yiiM, two novel determinants for resistance of Escherichia coli to N-hydroxylated base analogues
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Mol Microbiol 68:51-65. 2008
  6. pmc Molybdenum cofactor-dependent resistance to N-hydroxylated base analogs in Escherichia coli is independent of MobA function
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Mutat Res 619:9-15. 2007
  7. pmc A critical role for the putative NCS2 nucleobase permease YjcD in the sensitivity of Escherichia coli to cytotoxic and mutagenic purine analogs
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    MBio 4:e00661-13. 2013

Detail Information

Publications7

  1. pmc Genetic characterization of moaB mutants of Escherichia coli
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Res Microbiol 164:689-94. 2013
    ..On the other hand, in-frame deletions of moaB, or moaB overexpression, had no effect on either phenotype. Our combined data are consistent with the lack of any role for MoaB in Moco biosynthesis in E. coli. ..
  2. pmc The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells
    Stanislav G Kozmin
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA
    Genetics 193:803-17. 2013
    ..The requirement for specific DNA-damage checkpoint proteins suggests roles in recruiting and/or activating factors required to fill such gaps...
  3. pmc TusA (YhhP) and IscS are required for molybdenum cofactor-dependent base-analog detoxification
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709
    Microbiologyopen 2:743-55. 2013
    ..Overall, our data imply a novel and indispensable role of the IscS/TusA complex in the activity of several molybdoenzymes...
  4. pmc Role for CysJ flavin reductase in molybdenum cofactor-dependent resistance of Escherichia coli to 6-N-hydroxylaminopurine
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, MD E3 01, National Institute of Environmental Health Sciences, 111 TW Alexander Drive, Research Triangle Park, NC 27709, USA
    J Bacteriol 192:2026-33. 2010
    ..In support of the proposed interaction of the CysJ and YcbX proteins, we show that an apparent CysJ-YcbX "hybrid" protein from two Vibrio species is capable of compensating for a double cysJ ycbX defect in E. coli...
  5. pmc YcbX and yiiM, two novel determinants for resistance of Escherichia coli to N-hydroxylated base analogues
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Mol Microbiol 68:51-65. 2008
    ..Instead, YcbX and YiiM may represent novel MoCo-dependent enzymatic activities. We also demonstrate that the MoCo/YcbX/YiiM-dependent detoxification of HAP proceeds by reduction to adenine...
  6. pmc Molybdenum cofactor-dependent resistance to N-hydroxylated base analogs in Escherichia coli is independent of MobA function
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Mutat Res 619:9-15. 2007
    ..Further, we establish that protection against the analogs does not require the common molybdopterin guanine-dinucleotide (MGD) form of the cofactor, but instead the guanosine monophosphate (GMP)-free version of MoCo (MPT) is sufficient...
  7. pmc A critical role for the putative NCS2 nucleobase permease YjcD in the sensitivity of Escherichia coli to cytotoxic and mutagenic purine analogs
    Stanislav G Kozmin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    MBio 4:e00661-13. 2013
    ..We also present data showing that this protein may, in fact, also be a principal permease involved in transport of the normal purines guanine, hypoxanthine, and/or xanthine...