Lee W Jones

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Exercise behavior, functional capacity, and survival in adults with malignant recurrent glioma
    Emily Ruden
    Duke University Medical Center, Durham, NC 27710, USA
    J Clin Oncol 29:2918-23. 2011
  2. pmc The lung cancer exercise training study: a randomized trial of aerobic training, resistance training, or both in postsurgical lung cancer patients: rationale and design
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA
    BMC Cancer 10:155. 2010
  3. doi request reprint Effects of presurgical exercise training on systemic inflammatory markers among patients with malignant lung lesions
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Appl Physiol Nutr Metab 34:197-202. 2009
  4. doi request reprint Safety and feasibility of aerobic training on cardiopulmonary function and quality of life in postsurgical nonsmall cell lung cancer patients: a pilot study
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Cancer 113:3430-9. 2008
  5. ncbi request reprint Cardiovascular reserve and risk profile of postmenopausal women after chemoendocrine therapy for hormone receptor--positive operable breast cancer
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Oncologist 12:1156-64. 2007
  6. pmc Quantitative assessment of cardiorespiratory fitness, skeletal muscle function, and body composition in adults with primary malignant glioma
    Lee W Jones
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Cancer 116:695-704. 2010
  7. pmc Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA
    J Clin Oncol 30:2530-7. 2012
  8. ncbi request reprint Early breast cancer therapy and cardiovascular injury
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 50:1435-41. 2007
  9. pmc Rationale and design of the Exercise Intensity Trial (EXCITE): A randomized trial comparing the effects of moderate versus moderate to high-intensity aerobic training in women with operable breast cancer
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA
    BMC Cancer 10:531. 2010
  10. pmc Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy
    Lee W Jones
    Duke Cancer Institute, Duke University Medical Center, Box 3085, Durham, NC 27710, USA
    Cancer Prev Res (Phila) 6:925-37. 2013

Detail Information

Publications43

  1. pmc Exercise behavior, functional capacity, and survival in adults with malignant recurrent glioma
    Emily Ruden
    Duke University Medical Center, Durham, NC 27710, USA
    J Clin Oncol 29:2918-23. 2011
    ..We investigated the prognostic significance of exercise behavior and functional capacity in this population...
  2. pmc The lung cancer exercise training study: a randomized trial of aerobic training, resistance training, or both in postsurgical lung cancer patients: rationale and design
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA
    BMC Cancer 10:155. 2010
    ....
  3. doi request reprint Effects of presurgical exercise training on systemic inflammatory markers among patients with malignant lung lesions
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Appl Physiol Nutr Metab 34:197-202. 2009
    ....
  4. doi request reprint Safety and feasibility of aerobic training on cardiopulmonary function and quality of life in postsurgical nonsmall cell lung cancer patients: a pilot study
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Cancer 113:3430-9. 2008
    ..A feasibility study examining the effects of supervised aerobic exercise training on cardiopulmonary and quality of life (QOL) endpoints among postsurgical nonsmall cell lung cancer (NSCLC) patients was conducted...
  5. ncbi request reprint Cardiovascular reserve and risk profile of postmenopausal women after chemoendocrine therapy for hormone receptor--positive operable breast cancer
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Oncologist 12:1156-64. 2007
    ..AI therapy may be associated with a more unfavorable cardiovascular risk profile than TAM. Prospective studies are required to further investigate the clinical value of these findings...
  6. pmc Quantitative assessment of cardiorespiratory fitness, skeletal muscle function, and body composition in adults with primary malignant glioma
    Lee W Jones
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Cancer 116:695-704. 2010
    ..The study was undertaken to evaluate cardiorespiratory fitness, skeletal muscle function, and body composition of patients with newly diagnosed and untreated, postsurgical primary malignant glioma...
  7. pmc Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA
    J Clin Oncol 30:2530-7. 2012
    ..To evaluate cardiopulmonary function (as measured by peak oxygen consumption [VO(2peak)]) across the breast cancer continuum and its prognostic significance in women with metastatic disease...
  8. ncbi request reprint Early breast cancer therapy and cardiovascular injury
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 50:1435-41. 2007
    ....
  9. pmc Rationale and design of the Exercise Intensity Trial (EXCITE): A randomized trial comparing the effects of moderate versus moderate to high-intensity aerobic training in women with operable breast cancer
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA
    BMC Cancer 10:531. 2010
    ....
  10. pmc Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy
    Lee W Jones
    Duke Cancer Institute, Duke University Medical Center, Box 3085, Durham, NC 27710, USA
    Cancer Prev Res (Phila) 6:925-37. 2013
    ..Data from this exploratory study provide initial evidence that AET can modulate several host- and tumor-related pathways during standard chemotherapy. The biologic and clinical implications remain to be determined...
  11. pmc Changes in functional performance measures in adults undergoing chemoradiation for primary malignant glioma: a feasibility study
    Lee W Jones
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Oncologist 15:636-47. 2010
    ..To investigate the feasibility of longitudinal assessment of functional performance measures in newly diagnosed postsurgical malignant glioma patients...
  12. ncbi request reprint Effects of presurgical exercise training on cardiorespiratory fitness among patients undergoing thoracic surgery for malignant lung lesions
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Cancer 110:590-8. 2007
    ..To determine the effects of preoperative exercise training on cardiorespiratory fitness in patients undergoing thoracic surgery for malignant lung lesions...
  13. ncbi request reprint Cardiovascular risk profile of patients with HER2/neu-positive breast cancer treated with anthracycline-taxane-containing adjuvant chemotherapy and/or trastuzumab
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Box 3624, Durham, NC 27710, USA
    Cancer Epidemiol Biomarkers Prev 16:1026-31. 2007
    ..We measured 14 metabolic and vascular established cardiovascular disease (CVD) risk factors, body mass index, cardiorespiratory fitness, and left ventricular systolic function. All assessments were done within a 14-day period...
  14. pmc A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma
    David A Reardon
    Department of Surgery, The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, NC 27710, USA
    J Natl Compr Canc Netw 9:414-27. 2011
    ..Better understanding of resistance mechanisms to VEGF inhibitors and identification of effective therapy after bevacizumab progression are currently a critical need for patients with glioblastoma...
  15. ncbi request reprint Exercise therapy across the lung cancer continuum
    Lee W Jones
    Duke University Medical Center, Durham, NC 27710, USA
    Curr Oncol Rep 11:255-62. 2009
    ..Preliminary evidence in this area suggests that exercise therapy may be an important consideration in multidisciplinary management of patients diagnosed with lung cancer...
  16. pmc Prognostic significance of functional capacity and exercise behavior in patients with metastatic non-small cell lung cancer
    Lee W Jones
    Duke Cancer Institute, Durham, NC 27710, USA
    Lung Cancer 76:248-52. 2012
    ..To investigate the prognostic importance of functional capacity and exercise behavior in patients with metastatic non-small cell lung cancer (NSCLC)...
  17. pmc Effect of exercise training on peak oxygen consumption in patients with cancer: a meta-analysis
    Lee W Jones
    Box 3085, Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Oncologist 16:112-20. 2011
    ..We conducted a meta-analysis to determine the effects of supervised exercise training on peak oxygen consumption (VO(2peak)) in adults with cancer...
  18. doi request reprint Peak oxygen consumption and long-term all-cause mortality in nonsmall cell lung cancer
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Cancer 116:4825-32. 2010
    ..The authors investigated the prognostic significance of preoperative cardiorespiratory fitness (peak oxygen consumption [VO(2peak)]) among operable candidates with NSCLC...
  19. doi request reprint Cardiorespiratory exercise testing in clinical oncology research: systematic review and practice recommendations
    Lee W Jones
    Duke University Medical Centre, Durham, NC 27710, USA
    Lancet Oncol 9:757-65. 2008
    ..Overall, we present information for clinicians and exercise-oncology researchers who assess and care for patients with cancer...
  20. ncbi request reprint Relationship between exercise behavior, cardiorespiratory fitness, and cognitive function in early breast cancer patients treated with doxorubicin-containing chemotherapy: a pilot study
    Theresa Crowgey
    a Duke University Medical Center, Durham, NC 27710, USA
    Appl Physiol Nutr Metab 39:724-9. 2014
    ....
  21. doi request reprint Effects of nonlinear aerobic training on erectile dysfunction and cardiovascular function following radical prostatectomy for clinically localized prostate cancer
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA Electronic address
    Eur Urol 65:852-5. 2014
    ..There were no group differences in other markers of CV risk profile or PROs. In summary, nonlinear AT does not improve ED in men with localized prostate cancer in the acute period following RP...
  22. doi request reprint Association between exercise and primary incidence of prostate cancer: does race matter?
    Abhay A Singh
    Duke Prostate Center, Duke University Medical Center, Durham, NC 27705, USA
    Cancer 119:1338-43. 2013
    ..However, whether this association is different as a function of race is unclear. In the current study, the authors attempted to characterize the link between exercise and prostate cancer (CaP) in white and black American men...
  23. doi request reprint Exercise intolerance in cancer and the role of exercise therapy to reverse dysfunction
    Lee W Jones
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Lancet Oncol 10:598-605. 2009
    ..A better understanding of these issues might lead to more effective integration of exercise therapy to optimise the treatment and management of patients with cancer...
  24. pmc Effects of aerobic training on oxidative status in postsurgical non-small cell lung cancer patients: a pilot study
    Lee W Jones
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Lung Cancer 72:45-51. 2011
    ..We investigated the effects of supervised, moderate-intensity aerobic training on urinary markers of oxidative status in patients with postsurgical NSCLC...
  25. doi request reprint Evidence-based risk assessment and recommendations for physical activity clearance: cancer
    Lee W Jones
    Duke Cancer Institute, Durham, NC 27710, USA
    Appl Physiol Nutr Metab 36:S101-12. 2011
    ....
  26. pmc Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer
    Lee W Jones
    Duke University Medical Center, Durham, NC 27710, USA
    J Appl Physiol (1985) 113:263-72. 2012
    ..Exercise-induced stabilization of HIF-1α and subsequent upregulation of VEGF was associated with "productive" tumor vascularization with a shift toward suppressed metastasis in an orthotopic model of prostate cancer...
  27. doi request reprint Childhood cancer survivors' perceived barriers to improving exercise and dietary behaviors
    Whitney D Arroyave
    School of Nursing, Duke University, Durham, NC, USA
    Oncol Nurs Forum 35:121-30. 2008
    ..To determine childhood cancer survivors' barriers to increasing exercise and consuming less fat and more fruits and vegetables, whole grains, and calcium-rich foods...
  28. pmc Association between body mass index and mortality in patients with glioblastoma mutliforme
    Lee W Jones
    Department of Radiation Oncology, Duke University Medical Center, Box 3085, Durham, NC 27710, USA
    Cancer Causes Control 21:2195-201. 2010
    ..5-24.9 kg/m(2); overweight, 25.0-29.9 kg/m(2); obese, ≥ 30.0 kg/m(2))...
  29. pmc Effects and potential mechanisms of exercise training on cancer progression: a translational perspective
    Allison S Betof
    Duke Cancer Institute, Durham, NC 27710, USA
    Brain Behav Immun 30:S75-87. 2013
    ..Current gaps in knowledge are also discussed...
  30. doi request reprint Exercise-oncology research: past, present, and future
    Lee W Jones
    Duke Cancer Institute, Durham, NC 27710, USA
    Acta Oncol 52:195-215. 2013
    ..Against this background, we overview the extant literature base together with ongoing/planned studies examining the role of exercise therapy following a cancer diagnosis with a view towards identifying major gaps in the knowledge...
  31. doi request reprint Physical activity and lung cancer survivorship
    Lee W Jones
    Department of Surgery, Duke University Medical Center, 3085, Durham, NC 27710, USA
    Recent Results Cancer Res 186:255-74. 2011
    ..Preliminary evidence in this area supports that exercise therapy may be an important consideration in multidisciplinary management of patients diagnosed with lung cancer...
  32. pmc Effect of aerobic exercise on tumor physiology in an animal model of human breast cancer
    Lee W Jones
    Duke Univ Medical Center, Durham, NC 27710, USA
    J Appl Physiol (1985) 108:343-8. 2010
    ..Such findings may have important implications for inhibiting tumor metastasis and improving the efficacy of conventional cancer therapies...
  33. doi request reprint Erratum to: Exercise therapy in the management of solid tumors
    Lee W Jones
    Duke University Medical Center, Box 3085, Durham, NC 27710, USA
    Curr Treat Options Oncol 11:73-86. 2010
    ..Preliminary evidence in this area supports that exercise therapy may be an important consideration in multidisciplinary management of patients following a cancer diagnosis...
  34. doi request reprint Utility of 3-dimensional echocardiography, global longitudinal strain, and exercise stress echocardiography to detect cardiac dysfunction in breast cancer patients treated with doxorubicin-containing adjuvant therapy
    Michel G Khouri
    Duke Cancer Institute, Duke University Medical Center, Box 3085, Durham, NC, 27710, USA
    Breast Cancer Res Treat 143:531-9. 2014
    ..Post-exercise increase in cardiac index predicted VO2peak (r = 0.429, p = 0.001). Resting 3DE, GLS, and exercise stress 2DE detect subclinical cardiac dysfunction not apparent with resting 2DE in post-DOX breast cancer patients...
  35. doi request reprint Safety and efficacy of aerobic training in operable breast cancer patients receiving neoadjuvant chemotherapy: a phase II randomized trial
    Whitney E Hornsby
    Duke University Medical Center, Durham, North Carolina, USA
    Acta Oncol 53:65-74. 2014
    ..To evaluate the safety and efficacy of moderate-to-high intensity aerobic training in breast cancer patients receiving neoadjuvant chemotherapy...
  36. ncbi request reprint Safety and feasibility of cardiopulmonary exercise testing in patients with advanced cancer
    Lee W Jones
    Duke University Medical Center, Durham, NC, USA
    Lung Cancer 55:225-32. 2007
    ..Accordingly, we conducted a pilot study to comprehensively evaluate the safety and feasibility of CPET in 85 patients diagnosed with inoperable non-small cell lung cancer (NSCLC) or metastatic breast cancer (MBC)...
  37. pmc Exercise therapy in the management of solid tumors
    Lee W Jones
    Duke University Medical Center, Box 3085, Durham, NC 27710, USA
    Curr Treat Options Oncol 11:45-58. 2010
    ..Preliminary evidence in this area supports that exercise therapy may be an important consideration in multidisciplinary management of patients following a cancer diagnosis...
  38. ncbi request reprint Assessment of physical functioning in recurrent glioma: preliminary comparison of performance status to functional capacity testing
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Box 3624, Durham, NC 27710, USA
    J Neurooncol 94:79-85. 2009
    ..We conducted a pilot study to explore the feasibility and clinical utility of functional capacity testing to assess physical functioning in recurrent primary malignant glioma patients...
  39. pmc Recreational physical activity and ovarian cancer risk and survival
    Patricia G Moorman
    Cancer Prevention, Detection and Control Research Program, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27705, USA
    Ann Epidemiol 21:178-87. 2011
    ..We examined associations between self-reported physical activity and ovarian cancer risk and survival in a population-based, case-control study in North Carolina...
  40. pmc Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation
    Sarah J E Wong-Goodrich
    Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708, USA
    Cancer Res 70:9329-38. 2010
    ..Our findings show that running can abrogate this memory decline and aid recovery of adult hippocampal plasticity, thus highlighting exercise as a potential therapeutic intervention...
  41. ncbi request reprint Overweight and obese perimenopausal and postmenopausal women exhibit increased abnormal mammary epithelial cytology
    Victoria L Seewaldt
    Department of Medicine, Duke University Medical Center, Box 2628, Durham, NC 27710, USA
    Cancer Epidemiol Biomarkers Prev 16:613-6. 2007
    ..Further research is needed to confirm these findings and to determine if this potential biomarker is responsive to changes in body weight resulting from diet and/or exercise interventions...
  42. ncbi request reprint Exercise and prostate cancer risk in a cohort of veterans undergoing prostate needle biopsy
    Jodi A Antonelli
    Duke Prostate Center, Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 182:2226-31. 2009
    ..We further characterized this relationship by examining exercise and cancer risk among men undergoing prostate needle biopsy...
  43. ncbi request reprint Diet, exercise, and complementary therapies after primary treatment for cancer
    Lee W Jones
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Lancet Oncol 7:1017-26. 2006
    ..Overall, this review provides important information to oncology care providers who counsel their patients on preventive lifestyle practices to maximise health and longevity after a diagnosis of cancer...