Research Topics
| W JiangSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Publications
Prevalence and clinical characteristics of mental stress-induced myocardial ischemia in patients with coronary heart diseaseWei Jiang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina Department of Medicine, Duke University Medical Center, Durham, North Carolina Electronic address
J Am Coll Cardiol 61:714-22. 2013..The goal of this study was to evaluate the prevalence and clinical characteristics of mental stress-induced myocardial ischemia...
Plasma omega-3 polyunsaturated fatty acids and survival in patients with chronic heart failure and major depressive disorderWei Jiang
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
J Cardiovasc Transl Res 5:92-9. 2012..1 unit) (HR 0.73, 95% CI 0.56-0.96) were significantly associated with survival of patients with HF and co-morbid MDD. The results suggest that low plasma omega-3 FA is a significant factor for reduced survival in HF patients with MDD...
Acute psychotic disorder after gastric bypass surgery: differential diagnosis and treatmentWei Jiang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Am J Psychiatry 163:15-9. 2006
Prognostic value of anxiety and depression in patients with chronic heart failureWei Jiang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Circulation 110:3452-6. 2004..In a secondary analysis of data collected for a published study of depression and prognosis in patients with CHF, we examined the relations among anxiety, depression, and prognosis...
Relationship between depressive symptoms and long-term mortality in patients with heart failureWei Jiang
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 154:102-8. 2007..The study sought to assess the association of depressive symptoms and long-term mortality of patients with HF and to explore the prognostic predictability of the Beck Depression Inventory (BDI) scale for patients with HF...
Impacts of depression and emotional distress on cardiac diseaseWei Jiang
Duke University Medical Center, Durham, NC 27710, USA
Cleve Clin J Med 75:S20-5. 2008..Early evidence suggests that antidepressant therapy with SSRIs may be associated with improved cardiac outcomes in depressed cardiac patients, but further study is needed...
Should selective serotonin reuptake inhibitors be prescribed to all patients with ischemic heart disease?Wei Jiang
Department of Psychiatry and Behavioral Sciences, Department of Medicine, Duke University Medical Center, PO Box 3366, Durham, NC 27710, USA
Curr Psychiatry Rep 6:202-9. 2004....
Safety and efficacy of sertraline for depression in patients with CHF (SADHART-CHF): a randomized, double-blind, placebo-controlled trial of sertraline for major depression with congestive heart failureWei Jiang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 156:437-44. 2008..The impact of sertraline on the prognosis and depression of patients with chronic heart failure (HF) and comorbid major depressive disorder (MDD) is unknown...
Depression and increased myocardial ischemic activity in patients with ischemic heart diseaseWei Jiang
Departments of Department ofPsychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 146:55-61. 2003..The observed inverse association between higher level of depressive symptoms and ischemic activity needs to be further assessed in large samples...
Depression and ischemic heart disease: overview of the evidence and treatment implicationsWei Jiang
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Box 3366, Durham, NC 27710, USA
Curr Psychiatry Rep 5:47-54. 2003..In this article, the authors review the evidence that depression is a risk factor for ischemic heart disease and examine the efficacy and safety of depression treatments in patients with ischemic heart disease...
Characteristics of depression remission and its relation with cardiovascular outcome among patients with chronic heart failure (from the SADHART-CHF Study)Wei Jiang
Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
Am J Cardiol 107:545-51. 2011..5, Beck Depression Inventory scale 17.9 ± 6.5 vs 20.3 ± 7.2, p <0.001 for the 2 comparisons). In conclusion, this study indicates that remission from depression may improve the cardiovascular outcome of patients with heart failure...
Effects of pregabalin on heart rate variability in patients with painful diabetic neuropathyWei Jiang
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychopharmacol 31:207-13. 2011..In conclusion, 4-week pregabalin treatment improved HRV in patients with painful diabetic peripheral neuropathy. Trial Registration: NCT00573261 (clinicaltrials.gov)...
Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failureW Jiang
Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
Arch Intern Med 161:1849-56. 2001..Patients with congestive heart failure (CHF) may have a high prevalence of depression, which may increase the risk of adverse outcomes...
Responses of mental stress-induced myocardial ischemia to escitalopram treatment: background, design, and method for the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment trialWei Jiang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
Am Heart J 163:20-6. 2012..Depression is a risk factor of MSIMI. The REMIT trial investigates whether selective serotonin reuptake inhibitor (SSRI) treatment can improve MSIMI. The rationale and outline of the study are described...
Antidepressant therapy in patients with ischemic heart diseaseWei Jiang
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 150:871-81. 2005....
Effects of mental stress on myocardial ischemia during daily lifeE C Gullette
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
JAMA 277:1521-6. 1997..To determine the relative risk of myocardial ischemia triggered by specific emotions during daily life...
Emotional responsivity and transient myocardial ischemiaR A Carels
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
J Consult Clin Psychol 67:605-10. 1999..These results suggest that emotional responsivity may represent an individual difference characteristic that is associated with an increased likelihood of exhibiting myocardial ischemia in both the laboratory and the real-world setting...
Depression and ischemic heart disease: what have we learned so far and what must we do in the future?Wei Jiang
Department of Internal Medicine and Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 150:54-78. 2005
Antidepressant use, depression, and survival in patients with heart failureCHRISTOPHER M O'CONNOR
Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, 2400 N Pratt St, Box 3356, Durham, NC 27705, USA
Arch Intern Med 168:2232-7. 2008..Because depression has also been shown to be associated with increased mortality in these patients, it remains unclear if this association is attributable to the use of antidepressants or to depression...
Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trialCHRISTOPHER M O'CONNOR
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
J Am Coll Cardiol 56:692-9. 2010..The objective was to test the hypothesis that heart failure (HF) patients treated with sertraline will have lower depression scores and fewer cardiovascular events compared with placebo...
The association between depression and chronic kidney disease and mortality among patients hospitalized with congestive heart failureS Susan Hedayati
Department of Medicine, Division of Nephrology, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
Am J Kidney Dis 44:207-15. 2004..The point prevalence of depression and its relationship to poor outcomes among patients with chronic kidney disease (CKD) has not been fully characterized...
A randomized, controlled, trial of controlled release paroxetine in fibromyalgiaAshwin A Patkar
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27704, USA
Am J Med 120:448-54. 2007..We investigated the efficacy and tolerability of paroxetine controlled release, a selective serotonin reuptake inhibitor in fibromyalgia...
Depression and ischemic heart disease: what have we learned from clinical trials?Sarah Rivelli
Department of Internal Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Curr Opin Cardiol 22:286-91. 2007..Discuss the interplay of depression and ischemic heart disease. Studies demonstrate high prevalence of depression and its negative impact among patients with ischemic heart disease...
Prognosis of patients taking selective serotonin reuptake inhibitors before coronary artery bypass graftingGlen L Xiong
Department of Internal Medicine, Duke University Medical Center, Durham, North Carolina, USA
Am J Cardiol 98:42-7. 2006..26 to 1.70, p <0.0001, respectively). In conclusion, SSRI use before CABG was associated with a higher risk of long-term post-CABG mortality and rehospitalization. The explanation behind these findings requires further research...
Safety of selective serotonin reuptake inhibitor use prior to coronary artery bypass graftingGlen L Xiong
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina, USA
Clin Cardiol 33:E94-8. 2010..Selective serotonin reuptake inhibitors (SSRIs) have been shown to increase bleeding risks. This study examined the association of perioperative coronary artery bypass grafting (CABG) bleeding risks and SSRI use prior to CABG...
Depression and heart disease: evidence of a link, and its therapeutic implicationsWei Jiang
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27707, USA
CNS Drugs 16:111-27. 2002..In addition, no research has addressed whether the treatment of depression in patients with heart disease will improve their prognosis...
The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher diseaseCherie M Southwood
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA
Neuron 36:585-96. 2002..Thus, PMD represents the first member of a novel class of disparate degenerative diseases for which UPR activation and signaling is the common pathogenic mechanism...
[Clinical observation on quality of life in coronary artery bypass grafting patients treated according to syndrome differentiation of TCM]Xin min Ruan
Heart Center, Guangdong Provincial Hospital of TCM, Guangzhou 510105
Zhongguo Zhong Xi Yi Jie He Za Zhi 23:804-7. 2003..To evaluate the clinical effect and quality of life (QOL) in coronary artery bypass grafting (CABG) patients treated according to syndrome differentiation of TCM...
Patients with CHF and depression have greater risk of mortality and morbidity than patients without depressionWei Jiang
J Am Coll Cardiol 39:919-21. 2002
Activation of platelet-activating factor receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancerMargarita Aponte
Laboratory of Gynecologic Oncology and Epidemiology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women s Hospital, Dana Farber Cancer Center, Harvard Medical School, Boston, Massachusetts 02115, USA
Cancer Res 68:5839-48. 2008..We suggest that PAFR is an essential upstream target of Src and other signal pathways to control the PAF-mediated cancer progression...
TTX-R Na+ current-reduction by celecoxib correlates with changes in PGE(2) and CGRP within rat DRG neurons during acute incisional painKe Ma
The Anesthesiology Department of Shanghai Sixth People s Hospital, Shanghai Jiaotong University, 600 Yi Shan Road, Shanghai 200233, People s Republic of China
Brain Res 1209:57-64. 2008..05). This study indicates that: 1) celecoxib can inhibit TTX-R sodium channel current density in rat DRG neurons; 2) PGE2 and CGRP participate in celecoxib's analgesic effect on acute incisional pain...
Inhibition of MPEP on the development of morphine antinociceptive tolerance and the biosynthesis of neuronal nitric oxide synthase in rat spinal cordTao Xu
Department of Anesthesiology, The Sixth Affiliated People s Hospital, Shanghai Jiaotong University, 600 Yi Shan Road, Shanghai 200233, China
Neurosci Lett 436:214-8. 2008..The synergistic effect which seems to exist between mGluRs and iGluRs may also contribute to this phenomenon...
Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injuryWei Jiang
Department of Physiology, 433 Botterell Hall, Stuart St, Queen s University, Kingston, ON K7L 3N6 Canada
Am J Pathol 172:592-602. 2008....
In vitro permeability of round window membrane to transforming dexamethasone with delivery vehicles--a dosage estimationJian Jun Sun
Center of Otolaryngology of PLA, Naval General Hospital, Beijing 100037, China
Chin Med J (Engl) 120:2284-9. 2007..The aim of this study was to use biodegradable vehicles to release dexamethasone in the round window membrane application...
Block-based neural networks for personalized ECG signal classificationWei Jiang
Department of Electrical and Computer Engineering, The University of Tennessee, Knoxville, TN 37996 2100, USA
IEEE Trans Neural Netw 18:1750-61. 2007..1%) and supraventricular ectopic beats (96.6%) patterns for heartbeat monitoring, being a significant improvement over previously reported electrocardiogram (ECG) classification results...
Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosteroneWei Jiang
Institute of Cardiovascular Disease, Peking University First Hospital, Beijing 100034, China
J Hypertens 22:1953-61. 2004..CONCLUSION: Aldosterone stimulates adventitia to produce and secrete ADM, which in turn, antagonizes the aldosterone-induced proliferation in adventitia...
Mild hypothermia protects against sodium taurocholate (NaTc)-induced acute pancreatitis in rats with adverse effects on serum cytokinesXuemin Wang
Department of Intensive Care Unit, Shanghai 6th Municipal Hospital, Medical College of Shanghai Jiao Tong University, Shanghai, China
Pancreas 30:e80-6. 2005..To test the effect of mild hypothermia in reducing pancreatic damage and improving the survival of acute hemorrhagic and necrotic pancreatitis (AHNP) in rats...
[Clinical efficacy of treatment for regulating Pi and protecting Xin in treating patients after coronary artery bypass grafting and its effect on patients' quality of life]Xin min Ruan
Heart Center, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou
Zhongguo Zhong Xi Yi Jie He Za Zhi 26:28-32. 2006..To evaluate the clinical efficacy of treatment for regulating Pi and protecting Xin (abbr. as CHM) and its effect on quality of life (QOL) in patients after coronary artery bypass grafting (CABG)...
[Study on TCM syndrome differentiation rules in coronary artery bypass grafting patients during peri-operation period]Wei Jiang
Heart Center, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120
Zhongguo Zhong Xi Yi Jie He Za Zhi 26:597-9. 2006..For patients after CABG, both deficiency and excess is the pathological characteristic, the Xin-qi and Xin-yang deficiency syndrome the commonest type, and with phlegm as the main pathologic factor...
